Page last updated: 2024-10-24

bupivacaine and Chronic Pancreatitis

bupivacaine has been researched along with Chronic Pancreatitis in 6 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"Triamcinolone does not increase pain relief or lengthen the effects of EUS-CPB."9.16Adding triamcinolone to endoscopic ultrasound-guided celiac plexus blockade does not reduce pain in patients with chronic pancreatitis. ( Costanzo, A; Kapural, L; Lopez, R; Parsi, MA; Stevens, T; Vargo, JJ, 2012)
"Triamcinolone does not increase pain relief or lengthen the effects of EUS-CPB."5.16Adding triamcinolone to endoscopic ultrasound-guided celiac plexus blockade does not reduce pain in patients with chronic pancreatitis. ( Costanzo, A; Kapural, L; Lopez, R; Parsi, MA; Stevens, T; Vargo, JJ, 2012)
"Thirty-three patients underwent 36 direct celiac ganglia injections for unresectable pancreatic cancer (CGN N = 17, CGB N = 1) or chronic pancreatitis (CGN N = 5, CGB N = 13) with bupivacaine (0."3.74Initial evaluation of the efficacy and safety of endoscopic ultrasound-guided direct Ganglia neurolysis and block. ( Chari, ST; Clain, JE; de la Mora, JG; Gleeson, FC; Levy, MJ; Pearson, RK; Pelaez, MC; Petersen, BT; Rajan, E; Topazian, MD; Vege, SS; Wang, KK; Wiersema, MJ, 2008)
"Chronic abdominal pain is a devastating problem for patients and providers, due to the difficulty of effectively treating the entity."2.50Celiac plexus block in the management of chronic abdominal pain. ( Candido, KD; Knezevic, NN; Raja, O; Rana, MV, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rana, MV1
Candido, KD1
Raja, O1
Knezevic, NN1
Santosh, D1
Lakhtakia, S1
Gupta, R1
Reddy, DN1
Rao, GV1
Tandan, M1
Ramchandani, M1
Guda, NM1
Sahai, AV2
Wyse, J1
Stevens, T1
Costanzo, A1
Lopez, R1
Kapural, L1
Parsi, MA1
Vargo, JJ1
Gimeno-GarcĂ­a, AZ1
Elwassief, A1
Paquin, SC1
Levy, MJ1
Topazian, MD1
Wiersema, MJ1
Clain, JE1
Rajan, E1
Wang, KK1
de la Mora, JG1
Gleeson, FC1
Pearson, RK1
Pelaez, MC1
Petersen, BT1
Vege, SS1
Chari, ST1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Paragastric Neural Block in Controlling Pain, Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy; Prospective Randomized Controlled Double-blind Study[NCT05984160]90 participants (Actual)Interventional2023-05-09Active, not recruiting
A Randomized Controlled Trial on Endoscopic Ultrasound-guided Celiac Ganglion Neurolysis Versus Percutaneous Celiac Plexus Neurolysis in Patients With Inoperable Cancer[NCT02356640]Phase 2/Phase 33 participants (Actual)Interventional2014-08-31Terminated (stopped due to Poor recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for bupivacaine and Chronic Pancreatitis

ArticleYear
Celiac plexus block in the management of chronic abdominal pain.
    Current pain and headache reports, 2014, Volume: 18, Issue:2

    Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea

2014

Trials

2 trials available for bupivacaine and Chronic Pancreatitis

ArticleYear
Clinical trial: a randomized trial comparing fluoroscopy guided percutaneous technique vs. endoscopic ultrasound guided technique of coeliac plexus block for treatment of pain in chronic pancreatitis.
    Alimentary pharmacology & therapeutics, 2009, May-01, Volume: 29, Issue:9

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Autonomic Nerv

2009
Adding triamcinolone to endoscopic ultrasound-guided celiac plexus blockade does not reduce pain in patients with chronic pancreatitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2012, Volume: 10, Issue:2

    Topics: Adult; Anesthetics, Local; Bupivacaine; Celiac Plexus; Drug Therapy, Combination; Endoscopy; Female;

2012

Other Studies

3 other studies available for bupivacaine and Chronic Pancreatitis

ArticleYear
EUS-guided celiac plexus block for chronic pancreatitis: a placebo-controlled trial should be the first priority.
    Gastrointestinal endoscopy, 2010, Volume: 71, Issue:2

    Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Dose-Response Relationship, Drug;

2010
Fatal complication after endoscopic ultrasound-guided celiac plexus neurolysis.
    Endoscopy, 2012, Volume: 44 Suppl 2 UCTN

    Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Pain; Endosonography; Ethanol; Fatal Outc

2012
Initial evaluation of the efficacy and safety of endoscopic ultrasound-guided direct Ganglia neurolysis and block.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Ag

2008