bupivacaine and Chronic Illness studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

Excerpt	Relevance	Reference
" However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing."	9.14	[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010)
"Twelve patients with inadequate pain control already receiving intrathecal opioids and low dose bupivacaine."	9.14	Stability and tolerability of high concentrations of intrathecal bupivacaine and opioid mixtures in chronic noncancer pain: an open-label pilot study. ( Dusci, LJ; Fairclough, D; Goucke, CR; Ilett, KF; Van Leeuwen, S, 2010)
"A total of 15 patients suffering from chronic low back pain were treated with an intradiscal injection of either 1 ml of 50% glycerol or 2 ml of 0."	9.08	Intradiscal glycerol or bupivacaine in the treatment of low back pain. ( Kirvelä, O; Kotilainen, E; Muittari, P, 1997)
"The IT pain treatment with bupivacaine (with or without buprenorphine) alleviated the "refractory" pain, but affected neither the associated symptoms and signs of the CRPS-I, nor its natural evolution."	7.70	Clinical experience using intrathecal (IT) bupivacaine infusion in three patients with complex regional pain syndrome type I (CRPS-I). ( Appelgren, L; Curelaru, I; Dahm, P; Lundborg, C; Nitescu, P, 1999)
"A 75-year-old woman with chronic low back pain was given bupivacaine and methylprednisolone epidurally through a catheter in the L1-L2 interspace."	7.68	Exaggerated epidural blockade resulting from unusual spread of bupivacaine in a patient with low back pain. ( Glynn, CJ; Jadad, AR; Popat, MT, 1991)
"The purpose of this study was to investigate whether regression of sensory analgesia during constant epidural bupivacaine infusion was different in postoperative patients with acute pain than in patients with chronic nonsurgical pain."	7.67	The roles of acute and chronic pain in regression of sensory analgesia during continuous epidural bupivacaine infusion. ( Bigler, D; Hjortsø, NC; Kehlet, H; Lund, C; Mogensen, T; Scott, NB, 1988)
"A case of long-term relief of pain after interpleural blockade with bupivacaine in a patient suffering from severe chronic pancreatitis is reported."	7.67	[Interpleural bupivacaine (Marcain) in the treatment of pain in a patient with chronic pancreatitis]. ( Ahlburg, P; Mølgaard, J; Noreng, MF, 1989)
"Shoulder pain is common after laparoscopic cholecystectomy (60."	6.69	Bupivacaine instillation into gallbladder bed after laparoscopic cholecystectomy: does it decrease shoulder pain? ( Al-Jaberi, TM; Gharaibeh, KI, 2000)
"The paraplegia was permanent."	5.27	Paraplegia following epidural potassium chloride. ( Nishkala, R; Palkar, NV; Shanker, KB, 1985)
" However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing."	5.14	[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010)
"Twelve patients with inadequate pain control already receiving intrathecal opioids and low dose bupivacaine."	5.14	Stability and tolerability of high concentrations of intrathecal bupivacaine and opioid mixtures in chronic noncancer pain: an open-label pilot study. ( Dusci, LJ; Fairclough, D; Goucke, CR; Ilett, KF; Van Leeuwen, S, 2010)
"For this study, 60 patients with chronic cholecystitis were divided into four groups of 15 each: group A (bupivacaine-soaked Surgicel kept in gallbladder bed), group B (bupivacaine infiltrated at trocar sites), group C (bupivacaine infiltrated into the gallbladder bed and at trocar sites, and group D (normal saline in the gallbladder bed and at trocar sites)."	5.12	Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy. ( Bala, I; Kaman, L; Lyngdoh, TS; Verma, GR, 2006)
"Eligible patients with radicular pain who had unilateral symptoms who failed conservative management were randomized for a single injection with bupivacaine and methylprednisolone or bupivacaine only."	5.11	The efficacy of corticosteroids in periradicular infiltration for chronic radicular pain: a randomized, double-blind, controlled trial. ( Chaudhary, N; Ng, L; Sell, P, 2005)
"We have investigated correlation between postoperative pain and chest tube insertion after video-assisted thoracoscopic surgery (VATS) for patients with spontaneous pneumothorax, and have evaluated preemptive analgesia by intercostal nerve block (ICB) using bupivacaine."	5.11	[Evaluation of postoperative pain relief after video-assisted thoracoscopic surgery (VATS) for spontaneous pneumothorax]. ( Beppu, S; Hashimoto, S; Matsuo, T; Muzuta, M; Ohtsuka, S; Yoshioka, M, 2004)
"Factors affecting the spread of bupivacaine in the paravertebral space were investigated in patients undergoing paravertebral nerve blocks for the treatment of chronically painful conditions."	5.10	Factors affecting the spread of bupivacaine in the adult thoracic paravertebral space. ( Cheema, S; McGurgan, P; Richardson, J, 2003)
"A total of 15 patients suffering from chronic low back pain were treated with an intradiscal injection of either 1 ml of 50% glycerol or 2 ml of 0."	5.08	Intradiscal glycerol or bupivacaine in the treatment of low back pain. ( Kirvelä, O; Kotilainen, E; Muittari, P, 1997)
"Sixteen men and 25 women with pain in one or more cervical zygapophyseal joints after automobile accidents (mean age, 43 years; median duration of pain, 39 months) were randomly assigned to receive an intraarticular injection of either bupivacaine (0."	5.07	Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints. ( Barnsley, L; Bogduk, N; Lord, SM; Wallis, BJ, 1994)
"The study was conducted by retrospective investigation of the files of 92 patients experiencing chronic shoulder pain, and on whom a triple shoulder injection with 40 mg methylprednisolone and 25 mg bupivacaine accompanied by fluoroscopy was applied between January 01, 2011 and August 31, 2012."	3.80	[Effects of triple shoulder injection accompanied by fluoroscopy on pain experienced by patients with chronic shoulder pain]. ( Alagöl, A; Gümüş, F; Tuğ, A; Yektaş, A, 2014)
"Two patients with incapacitating symptoms from restless legs syndrome, not adequately responding to conventional treatment with dopaminergic drugs, were implanted with a pump device (Isomed) for intrathecal delivery of morphine and bupivacaine."	3.71	Successful treatment of restless legs syndrome with an implanted pump for intrathecal drug delivery. ( Jakobsson, B; Ruuth, K, 2002)
" Food and Drug Administration for chronic intrathecal infusion for the treatment of chronic pain is morphine sulfate."	3.71	Stability, compatibility, and safety of intrathecal bupivacaine administered chronically via an implantable delivery system. ( Deer, TR; Elsberry, DD; Hildebrand, KR, 2001)
"The IT pain treatment with bupivacaine (with or without buprenorphine) alleviated the "refractory" pain, but affected neither the associated symptoms and signs of the CRPS-I, nor its natural evolution."	3.70	Clinical experience using intrathecal (IT) bupivacaine infusion in three patients with complex regional pain syndrome type I (CRPS-I). ( Appelgren, L; Curelaru, I; Dahm, P; Lundborg, C; Nitescu, P, 1999)
" The current report details five children in whom a percutaneously placed lumbar intrathecal catheter was used: (i) to provide intraoperative surgical anaesthesia instead of general anaesthesia (ii); to deliver intrathecal fentanyl to provide postoperative analgesia (iii); to provide chronic pain control during the terminal stages of metastatic malignancy; (iv) to allow repeated doses of intrathecal chemotherapy; and (v) to allow CSF drainage and prevent CSF leakage following frontal encephalocele repair."	3.70	Applications of intrathecal catheters in children. ( Tobias, JD, 2000)
"A 75-year-old woman with chronic low back pain was given bupivacaine and methylprednisolone epidurally through a catheter in the L1-L2 interspace."	3.68	Exaggerated epidural blockade resulting from unusual spread of bupivacaine in a patient with low back pain. ( Glynn, CJ; Jadad, AR; Popat, MT, 1991)
"The purpose of this study was to investigate whether regression of sensory analgesia during constant epidural bupivacaine infusion was different in postoperative patients with acute pain than in patients with chronic nonsurgical pain."	3.67	The roles of acute and chronic pain in regression of sensory analgesia during continuous epidural bupivacaine infusion. ( Bigler, D; Hjortsø, NC; Kehlet, H; Lund, C; Mogensen, T; Scott, NB, 1988)
"A case of long-term relief of pain after interpleural blockade with bupivacaine in a patient suffering from severe chronic pancreatitis is reported."	3.67	[Interpleural bupivacaine (Marcain) in the treatment of pain in a patient with chronic pancreatitis]. ( Ahlburg, P; Mølgaard, J; Noreng, MF, 1989)
"In a double-blind study, 67 chronic low back pain patients received 4 lumbar sympathetic nerve blocks, two given with bupivacaine and two given with saline."	3.66	Learned helplessness and responses to nerve blocks in chronic low back pain patients. ( Brena, SF; Chapman, SL, 1982)
"The pharmacokinetic parameters for 50 patients undergoing continuous extravascular perineural bupivacaine infusions for the treatment of their chronic pain were studied."	3.66	Continuous perineural infusion of bupivacaine for prolonged analgesia: pharmacokinetic considerations. ( Denson, DD; Finnsson, RA; Joyce, TH; Raj, PP; Ritschel, WA; Saldahna, F; Turner, JL, 1983)
"The technique of large volume caudal extradural injection of a solution containing bupivacaine hydrochloride, hydrocortisone acetate and methylprednisolone acetate for low back pain is described."	3.66	Caudal extradural injection for the treatment of low back pain. ( Gordon, J, 1980)
"Bupivacaine help the lower pain values and less additional painkiller need after FESS."	2.82	Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? ( Arıkan, OK; Haytoğlu, S; Kuran, G; Muluk, NB, 2016)
"They were allowed a stable dose of migraine preventive medications that was maintained throughout the study."	2.80	A double-blind, placebo-controlled study of repetitive transnasal sphenopalatine ganglion blockade with tx360(®) as acute treatment for chronic migraine. ( Cady, R; Dexter, K; Manley, HR; Saper, J, 2015)
"Subjects were allowed a stable dose of migraine preventive medications that was maintained throughout the study."	2.80	Long-term efficacy of a double-blind, placebo-controlled, randomized study for repetitive sphenopalatine blockade with bupivacaine vs. saline with the Tx360 device for treatment of chronic migraine. ( Cady, RJ; Cady, RK; Dexter, K; Manley, HR; Saper, J, 2015)
"Significant improvement in plantar fasciitis symptoms was observed in patients receiving 0."	2.78	Prospective, randomized, blinded, comparative study of injectable micronized dehydrated amniotic/chorionic membrane allograft for plantar fasciitis--a feasibility study. ( Andrews, J; Poka, A; Zelen, CM, 2013)
"The operation time, postoperative pain, amount of intraoperative blood loss, postoperative hemorrhage and complications were assessed."	2.77	Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain. ( Kapusuz, Z; Ozkiriş, M; Saydam, L, 2012)
"The occurrence of chronic pain after inguinal hernia repair has been in focus of several clinical studies but the reduction of it has been rarely investigated."	2.73	Investigating the effect of intra-operative infiltration with local anaesthesia on the development of chronic postoperative pain after inguinal hernia repair. A randomized placebo controlled triple blinded and group sequential study design [NCT00484731]. ( Audigé, L; Fischer, H; Honigmann, P; Kurmann, A; Metzger, J; Schüpfer, G, 2007)
"Forty-two patients with chronic lower back pain who were undergoing facet joint blocks at one (n = 29) or two (n = 13) levels were analyzed."	2.72	Therapeutic efficacy of facet joint blocks. ( Boos, N; Elfering, A; Gorbach, C; Hodler, J; Schmid, MR, 2006)
"Different mechanisms underlie hyperalgesia localized at areas surrounding the site of pain and hyperalgesia generalized to distant body areas."	2.71	Modulation of central hypersensitivity by nociceptive input in chronic pain after whiplash injury. ( Arendt-Nielsen, L; Curatolo, M; Di Stefano, G; Herren-Gerber, R; Petersen-Felix, S; Radanov, BP; Weiss, S, 2004)
" Adverse events were uncommon, with no difference between groups."	2.71	Cost-effectiveness and safety of epidural steroids in the management of sciatica. ( Arden, N; Coglan, L; Price, C; Rogers, P, 2005)
"Shoulder pain is common after laparoscopic cholecystectomy (60."	2.69	Bupivacaine instillation into gallbladder bed after laparoscopic cholecystectomy: does it decrease shoulder pain? ( Al-Jaberi, TM; Gharaibeh, KI, 2000)
"Pain was scored on a visual analogue scale (0 to 100)."	2.68	Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder. ( Brox, JI; Røe, C; Saugen, E; Vøllestad, NK, 1997)
"No patient approached toxic plasma levels of bupivacaine."	2.68	Plasma concentrations of bupivacaine following single needle lumbar sympathectomy using two volumes of 0.25% bupivacaine plain solution. ( Dick, AM; Gabbott, DA; Hardy, PA, 1996)
"The incidence of new long term backache was not significantly increased in women who received epidural analgesia in labour."	2.68	Long term backache after childbirth: prospective search for causative factors. ( Dundas, R; Reynolds, F; Russell, R, 1996)
"Twenty-seven adults with cancer pain were prospectively selected according to their primary lesions and problems, but their allocation to study groups was randomized."	2.67	Prolongation of epidural bupivacaine analgesia with glycerin. ( King, H; Wooten, DJ; Xiao, CS, 1993)
"Chronic abdominal pain is a devastating problem for patients and providers, due to the difficulty of effectively treating the entity."	2.50	Celiac plexus block in the management of chronic abdominal pain. ( Candido, KD; Knezevic, NN; Raja, O; Rana, MV, 2014)
"In chronic migraine patients undergoing Greater occipital nerve (GON) block, mean number of days with pain per month before and after block, mean duration of pain in attacks (in hours), and mean Visual Analog Scale (VAS) in attack and pain severity were recorded from files."	1.46	Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients? ( Ataç-Uçar, C; İnan, LE; Ünal-Artık, HA; Yoldaş, TK, 2017)
"Hemiplegic shoulder pain is the most common pain condition after stroke."	1.46	Suprascapular nerve block for the treatment of hemiplegic shoulder pain in patients with long-term chronic stroke: a pilot study. ( Bonazza, S; Chemello, E; Gandolfi, M; Lobba, D; Martini, A; Parolini, M; Picelli, A; Polati, E; Schweiger, V; Smania, N, 2017)
"The pathophysiology of many types of chronic headaches is not well understood."	1.33	Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis? ( Cook, AJ; Hamill-Ruth, RJ; Rowlingson, JC; Yi, X, 2005)
"Chronic anal fissure is the main cause of anal pain and is very common."	1.31	Open lateral sphincterotomy is still the best treatment for chronic anal fissure. ( Argov, S; Levandovsky, O, 2000)
" Thus, epidural BUP-MS appears to provide adequate postoperative analgesia while preventing withdrawal in opioid-dependent patients, if three times the normal dosage and duration of therapy are employed."	1.29	A comparison of postoperative epidural analgesia between patients with chronic cancer taking high doses of oral opioids versus opioid-naive patients. ( Bacon, DR; de Leon-Casasola, OA; Donaparthi, S; Lema, MJ; Myers, DP; Peppriell, J; Rempel, J, 1993)
"This study evaluated 20 chronic cancer pain patients who underwent abdominal surgery for tumor resection."	1.29	Epidural bupivacaine/sufentanil therapy for postoperative pain control in patients tolerant to opioid and unresponsive to epidural bupivacaine/morphine. ( de Leon-Casasola, OA; Lema, MJ, 1994)
"The paraplegia was permanent."	1.27	Paraplegia following epidural potassium chloride. ( Nishkala, R; Palkar, NV; Shanker, KB, 1985)
"Immediate relief of pain is experienced after the solution of local anaesthetic and steroid has been deposited deep within the fleshy portion of the muscle."	1.26	Chronic pain syndromes and their treatment. III. The piriformis syndrome. ( Wyant, GM, 1979)

Research

Studies (113)

Authors

Clinical Trials (35)

Trial Overview

Trial Outcomes

Acute Medications Usage

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (13.27)	18.7374
1990's	37 (32.74)	18.2507
2000's	40 (35.40)	29.6817
2010's	21 (18.58)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Picelli, A	1
Bonazza, S	1
Lobba, D	1
Parolini, M	1
Martini, A	1
Chemello, E	1
Gandolfi, M	1
Polati, E	1
Smania, N	1
Schweiger, V	1
Zyluk, A	1
Puchalski, P	1
Zelen, CM	1
Poka, A	1
Andrews, J	1
Rana, MV	1
Candido, KD	1
Raja, O	1
Knezevic, NN	1
Guedes-Martins, L	1
Graça, H	1
Saraiva, JP	1
Guedes, L	1
Gaio, R	1
Cerdeira, AS	1
Macedo, F	1
Almeida, H	1
Cady, R	1
Saper, J	2
Dexter, K	2
Manley, HR	2
Yektaş, A	1
Tuğ, A	1
Gümüş, F	1
Alagöl, A	1
Cady, RK	1
Cady, RJ	1
Haytoğlu, S	1
Kuran, G	1
Muluk, NB	1
Arıkan, OK	1
Gul, HL	1
Ozon, AO	1
Karadas, O	1
Koc, G	1
Inan, LE	2
Persson, M	1
Sörensen, J	1
Gerdle, B	1
Ünal-Artık, HA	1
Ataç-Uçar, C	1
Yoldaş, TK	1
Chan, O	1
O'Dowd, D	1
Padhiar, N	2
Morrissey, D	2
King, J	2
Jalan, R	2
Maffulli, N	2
Crisp, T	2
Khan, F	1
Frcr, OC	1
Borowsky, CD	1
Fagen, G	1
LeBlanc, JK	1
DeWitt, J	1
Johnson, C	1
Okumu, W	1
McGreevy, K	1
Symms, M	1
McHenry, L	1
Sherman, S	3
Imperiale, T	1
Mounir, K	1
Bensghir, M	1
Elmoqaddem, A	1
Massou, S	1
Belyamani, L	1
Atmani, M	1
Azendour, H	1
Drissi Kamili, N	1
Osborn, I	1
Sebeo, J	1
De Oliveira, GS	1
Charchaflieh, J	1
Walega, D	1
Goucke, CR	2
Dusci, LJ	1
Van Leeuwen, S	1
Fairclough, D	1
Ilett, KF	1
Simpson, DM	1
Tyrrell, J	1
De Ruiter, J	1
Campbell, FA	1
Wylde, V	1
Gooberman-Hill, R	1
Horwood, J	1
Beswick, A	1
Noble, S	1
Brookes, S	1
Smith, AJ	1
Pyke, M	1
Dieppe, P	1
Blom, AW	1
McCahon, RA	1
Ravenscroft, A	1
Hodgkinson, V	1
Evley, R	1
Hardman, J	1
Cortijo, E	1
Guerrero-Peral, ÁL	1
Herrero-Velázquez, S	1
Mulero, P	1
Pedraza, M	1
Barón, J	1
de la Cruz, C	1
Ruiz, M	1
Campos-Blanco, DM	1
Marco-Llorente, J	1
Rojo-Martínez, E	1
Fernández, R	1
Ozkiriş, M	1
Kapusuz, Z	1
Saydam, L	1
Dunn, J	1
Chang, FL	1
Huang, GS	1
Cherng, CH	1
Ho, ST	1
Wong, CS	1
Shanahan, EM	2
Ahern, M	1
Smith, M	1
Wetherall, M	2
Bresnihan, B	1
FitzGerald, O	2
Hough, DM	1
Wittenberg, KH	1
Pawlina, W	1
Maus, TP	1
King, BF	1
Vrtiska, TJ	1
Farrell, MA	1
Antolak, SJ	1
Cheema, S	1
Richardson, J	2
McGurgan, P	1
Gruber, H	1
Bodner, G	1
Muzuta, M	1
Beppu, S	1
Hashimoto, S	1
Yoshioka, M	1
Matsuo, T	1
Ohtsuka, S	1
Manchikanti, L	1
Boswell, MV	1
Singh, V	1
Pampati, V	1
Damron, KS	1
Beyer, CD	1
Smith, MD	1
Lott, CW	1
Slavotinek, J	1
Ahern, MJ	1
Laslett, M	1
Oberg, B	1
Aprill, CN	1
McDonald, B	1
Herren-Gerber, R	1
Weiss, S	1
Arendt-Nielsen, L	1
Petersen-Felix, S	1
Di Stefano, G	1
Radanov, BP	1
Curatolo, M	1
Ng, L	1
Chaudhary, N	1
Sell, P	1
McAllister, RK	1
McDavid, AJ	1
Meyer, TA	1
Bittenbinder, TM	1
Price, C	1
Arden, N	1
Coglan, L	1
Rogers, P	1
Yi, X	1
Cook, AJ	1
Hamill-Ruth, RJ	1
Rowlingson, JC	1
Naja, MZ	1
Al-Tannir, M	1
Naja, H	1
Ziade, MF	1
Zeidan, A	1
Gorbach, C	1
Schmid, MR	1
Elfering, A	1
Hodler, J	1
Boos, N	1
Verma, GR	1
Lyngdoh, TS	1
Kaman, L	1
Bala, I	1
Iohom, G	1
Abdalla, H	1
O'Brien, J	1
Szarvas, S	1
Larney, V	1
Buckley, E	1
Butler, M	1
Shorten, GD	1
Langford, CF	1
Udvari Nagy, S	1
Ghoniem, GM	1
Giri, S	1
Nixdorf, D	1
Ju, H	1
Feng, Y	1
Yang, BX	1
Wang, J	1
Honigmann, P	1
Fischer, H	1
Kurmann, A	1
Audigé, L	1
Schüpfer, G	1
Metzger, J	1
Chapman, SL	2
Brena, SF	2
Dautenhahn, D	1
Reynolds, AF	1
Darby, R	1
Fagraeus, L	1
Slocumb, JC	1
Gordon, J	1
Alberico, JG	1
Denson, DD	1
Raj, PP	1
Saldahna, F	1
Finnsson, RA	1
Ritschel, WA	1
Joyce, TH	1
Turner, JL	1
Stoyanov, M	1
Müller, H	1
Hempelmann, G	1
Cheema, SP	1
Ilsley, D	1
Sabanathan, S	1
Khoury, GF	1
Garland, DE	1
Stein, C	1
el-Dawlatly, AA	1
al-Faqih, SR	1
Lafont, ND	1
Boogaerts, JG	1
Legros, FJ	1
Wulf, H	1
Gleim, M	1
Mignat, C	1
Barnsley, L	2
Lord, SM	1
Wallis, BJ	1
Bogduk, N	2
Lord, S	1
de Leon-Casasola, OA	2
Lema, MJ	2
Erickson, SJ	1
Hogan, QH	1
Myers, DP	1
Donaparthi, S	1
Bacon, DR	1
Peppriell, J	1
Rempel, J	1
Billström, R	1
Blomberg, HM	1
Gado, K	1
Emery, P	1
King, H	1
Xiao, CS	1
Wooten, DJ	1
Russell, R	1
Dundas, R	1
Reynolds, F	1
Chan, VW	1
Faigel, DO	1
Veloso, KM	1
Long, WB	1
Kochman, ML	1
Verheijen, R	1
Slappendel, R	1
Jansen, JB	1
Crul, BJ	2
van Dongen, RT	2
Dick, AM	1
Gabbott, DA	1
Hardy, PA	1
Cappellino, A	1
Jokl, P	1
Ruwe, PA	1
Kotilainen, E	1
Muittari, P	1
Kirvelä, O	2
Brox, JI	1
Røe, C	1
Saugen, E	1
Vøllestad, NK	1
Antila, H	1
Ozüer, MZ	1
Gress, F	2
Schmitt, C	2
Ikenberry, S	2
Lehman, G	2
Lundborg, C	1
Dahm, P	1
Nitescu, P	1
Appelgren, L	1
Curelaru, I	1
Saberski, LR	1
Ahmad, M	1
Munir, MA	1
Brull, SJ	1
Argov, S	1
Levandovsky, O	1
Ceballos, A	1
Cabezudo, L	1
Bovaira, M	1
Fenollosa, P	1
Moro, B	1
Chester, M	1
Hammond, C	1
Leach, A	1
Gharaibeh, KI	1
Al-Jaberi, TM	1
Tobias, JD	1
Hol, PK	1
Kvarstein, G	1
Viken, O	1
Smedby, O	1
Tønnessen, TI	1
Fu, KY	1
Light, AR	1
Maixner, W	1
Ciaccia, D	1
Kim, KM	1
Kim, HS	1
Choi, KH	1
Ahn, WS	1
Bleeker, CP	1
Bremer, RC	1
Dongelmans, DA	1
Hildebrand, KR	1
Elsberry, DD	1
Deer, TR	1
Peleg, R	1
Binyamin, L	1
Jakobsson, B	1
Ruuth, K	1
Wyant, GM	1
Shuman, RL	1
Peters, RM	1
Levine, CB	1
Levin, BH	1
Parris, WC	1
Klein, DS	2
Klein, PW	1
Sanders, SH	1
Schmidt, RE	1
Popat, MT	1
Jadad, AR	1
Glynn, CJ	1
Raja, SN	1
Treede, RD	1
Davis, KD	1
Campbell, JN	1
Hastings, RH	1
McKay, WR	1
Graziotti, P	1
Ahlburg, P	2
Noreng, M	1
Mølgaard, J	2
Egebo, K	1
Plancarte, R	1
Amescua, C	1
Patt, RB	1
Aldrete, JA	1
Lilius, G	1
Laasonen, EM	1
Myllynen, P	1
Harilainen, A	1
Salo, L	1
Noreng, MF	1
Shir, Y	1
Shapira, S	1
Magora, F	1
Sjaastad, O	1
Aasly, J	1
Fredriksen, T	1
Wysocka Bakowska, MM	1
Mogensen, T	1
Scott, NB	1
Lund, C	1
Bigler, D	1
Hjortsø, NC	1
Kehlet, H	1
Shanker, KB	1
Palkar, NV	1
Nishkala, R	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Cryoneurolysis as a Drug Free Novel Treatment for Knee and Shoulder Pain Impairing Inpatient Neurological Rehabilitation[NCT05674604]		25 participants (Anticipated)	Observational	2022-10-10	Recruiting
Amnion-Based Injections in the Shoulder for Adhesive Capsulitis and Osteoarthritis[NCT03770546]		0 participants (Actual)	Interventional	2021-10-30	Withdrawn (stopped due to Failure of institution to reach agreement with company supplying injections)
Efficacy and Safety of Paragastric Neural Block in Controlling Pain, Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy; Prospective Randomized Controlled Double-blind Study[NCT05984160]		90 participants (Actual)	Interventional	2023-05-09	Active, not recruiting
Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache[NCT05365880]	Phase 2	20 participants (Anticipated)	Interventional	2022-03-23	Recruiting
Use of the Tx360 Nasal Applicator for Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine: A Double-blind Placebo-controlled Study[NCT01709708]	Phase 4	41 participants (Actual)	Interventional	2012-09-30	Completed
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463]	Early Phase 1	60 participants (Anticipated)	Interventional	2020-09-30	Not yet recruiting
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?[NCT03266926]		140 participants (Actual)	Observational [Patient Registry]	2017-02-01	Completed
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia: A Randomized Controlled Pilot Study[NCT04051203]	Phase 1	35 participants (Anticipated)	Interventional	2019-02-01	Active, not recruiting
Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649]	Phase 4	62 participants (Actual)	Interventional	2020-02-10	Completed
A Pilot Study Comparing Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) as a Treatment for Cervical Facetogenic Pain[NCT04392999]	Phase 2/Phase 3	55 participants (Actual)	Interventional	2021-02-01	Active, not recruiting
Functional Improvement and Ultrasound Tissue Characterisation of the Achilles Tendon Following Sodium Hyaluronate Injection for Plantaris Friction Syndrome[NCT03077009]	Phase 4	33 participants (Anticipated)	Interventional	2017-03-20	Recruiting
Comparison Between Intra-articular Pulsed Radiofrequency With Steroids Injection Versus Intra-articular Steroids Injection in Chronic Sacroiliac Joint Arthritis[NCT03564106]	Phase 2/Phase 3	40 participants (Actual)	Interventional	2019-03-01	Completed
Randomized Controlled Trial Of Minimally Invasive Sacroiliac Joint Fusion Compared To Radiofrequency Ablation For Sacroiliac Joint Dysfunction[NCT03230279]		0 participants (Actual)	Interventional	2018-09-30	Withdrawn (stopped due to Was not financed, Sponsor withdrawn)
The Effect of Intravenous Single Dose of Magnesium Sulphate on Attenuation of Hemodynamic Pressor Response After Myfield's Clamp Application During Craniotomies[NCT03318471]	Phase 4	60 participants (Actual)	Interventional	2016-02-29	Completed
Effect of Regional Anesthesia With Lidocaine on Perioperative Levels of Interleukin-1β, Interleukin-6 and Tumor Necrosis Factor-α in Blood and Cerebrospinal Fluid in Cerebral Aneurysm Patients[NCT03823482]		40 participants (Anticipated)	Interventional	2019-03-01	Enrolling by invitation
Partial Scalp Block Versus Fentanyl Infusion in Patients Undergoing Posterior Fossa Surgery Under General Anesthesia. A Randomized Control Trial[NCT04955236]	Phase 1	40 participants (Actual)	Interventional	2021-07-14	Completed
Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain: A Randomized Double Blinded Control Trial[NCT04128605]		86 participants (Anticipated)	Interventional	2019-07-11	Recruiting
Comparison of Efficacy and Safety of Two Different Ultrasound-Guided Suprascapular Nerve Block Techniques in Chronic Shoulder Pain: A Prospective Double-Blinded Randomized Controlled Study[NCT04938037]		80 participants (Anticipated)	Interventional	2021-06-01	Recruiting
Randomized Prospective Study to Evaluate Efficacy and Safety of Single Versus Multiple Injection Ultrasound Guided Paravertebral Blocks for Breast Surgery[NCT02852421]		70 participants (Actual)	Interventional	2013-08-31	Completed
Comparison of Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia Alone in Acute Rib fracturEs[NCT03919916]		58 participants (Anticipated)	Interventional	2021-05-28	Recruiting
Effect of Dexamethasone Dose and Route on Duration of Interscalene Brachial Plexus Block for Outpatient Arthroscopic Shoulder Surgery - A Randomized Controlled Trial[NCT02426736]	Phase 4	280 participants (Actual)	Interventional	2015-06-25	Completed
Prospective Randomized Controlled Trial (PRCT) Comparing Standard Analgesia With Multi-modal Targeted Operative and Port-Site Local Anesthesia for Post-Operative Pain Management in Elective Laparoscopic Cholecystectomy (LapChole)[NCT01972620]		63 participants (Actual)	Interventional	2010-02-28	Completed
Effectiveness for Postoperative Pain After Laparoscopic Cholecystectomy of 0,5% Bupivacaine-Soaked Tabotamp Placed in the Gallbladder Bed[NCT00599144]		45 participants (Actual)	Interventional	2007-01-31	Completed
Assessment Of Pain Subsidence And Sexual Function Amelioration Using Either Pelvic Rehabilitation Or Trigger Point Injections[NCT02022722]	Phase 4	36 participants (Anticipated)	Interventional	2013-08-31	Recruiting
Pain Control After VATS Anatomical Pulmonary Resections: Randomized Comparison Between Cryoanalgesia, Erector Spinae Plane Block and Epidural Catheter[NCT05993273]		75 participants (Anticipated)	Interventional	2023-04-05	Recruiting
Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery[NCT05255146]		100 participants (Anticipated)	Interventional	2023-12-31	Not yet recruiting
The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial[NCT06088602]		44 participants (Anticipated)	Interventional	2023-11-30	Not yet recruiting
Investigating the Effect of Intra-operative Infiltration With Local Anaesthesia on the Development of Chronic Postoperative Pain After Inguinal Hernia Repair. A Randomized Placebo Controlled Triple Blinded and Group Sequential Study Design[NCT00484731]		404 participants (Actual)	Interventional	2006-07-31	Completed
Evaluation of the Efficacy of Adding Magnesium Sulfate as an Adjuvant to Bupivacaine in Bilateral Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy[NCT05099250]		50 participants (Actual)	Interventional	2019-07-15	Completed
Analgesic and Hemodynamic Effects of Continuous Epidural Analgesia Compared to Paravertebral Block in Liver Resection Patients[NCT02909322]	Phase 4	50 participants (Anticipated)	Interventional	2016-04-30	Recruiting
A Comparison of Ultrasound-assisted Paravertebral Block and General Anesthesia for Outpatient Breast Cancer Surgery, a Prospective Randomized Trial[NCT00645138]	Phase 3	40 participants (Anticipated)	Interventional	2008-04-30	Completed
Comparison of the Effects of Perioperative Anesthesia Consumption of Ultrasound Guided Subcostal Transversus Abdominis Plane and Paravertebral Block in Laparoscopic Cholecystectomy[NCT02379780]		50 participants (Actual)	Interventional	2014-09-30	Completed
Paragastric Lesser Omentum Neural Block to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial Protocol.[NCT05353426]		145 participants (Actual)	Interventional	2021-08-13	Completed
Prospective Randomized Trial of EUS Guided Celiac Plexus Block for Chronic Pancreatitis[NCT02399800]		1 participants (Actual)	Interventional	2014-12-31	Terminated (stopped due to Low enrollment)
Cardiac Rehabilitation for the Treatment of Refractory Angina[NCT00411359]	Phase 3	42 participants (Actual)	Interventional	2006-12-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Number of acute medications used during Treatment period (6 weeks) and Follow-Up (4 weeks) (Group A vs. Group B). (NCT01709708)
Timeframe: 10 Weeks

Adverse Events

Intervention	Number of medications used (Mean)
Marcaine	29.3
Saline	47.4

Number of adverse events over the entire length of study (Group A vs. Group B). (NCT01709708)
Timeframe: 34 weeks

Change in Numeric Rating Scale (NRS)

Intervention	Number of Adverse Events (Mean)
Marcaine	7.67
Saline	5.29

Compare percentage change in Numeric Rating Scale (NRS) score from Before Procedure to 15-Minutes, Before Procedure to 30-Minutes, Before Procedure to 24-Hours After Procedure for all 12 treatments (Mean of all 12 treatments for each timepoint, comparing Group A to Group B). NRS is a likert scale ranging from 0-10 with 0 being no pain and 10 being worst possible pain. (NCT01709708)
Timeframe: 15 Minutes Post Treatment, 30 minutes Post Treatment and 24 hours Post Treatment, assessed up to 6 weeks

Headache Impact Test (HIT-6)

Intervention	percentage of change (Mean)
	15 Minutes Post Treatment	30 Minutes Post Treatment	24 Hours Post Treatment
Marcaine	-23.3	-27.7	-15.5
Saline	-4.31	-5.41	13.5

"Total Headache Impact Test (HIT-6) scores Pre-Treatment at Visit 2 vs. Post-Treatment (following final treatment), and at 1-Month Post-Treatment (Group A vs. Group B). HIT-6 is a series of 6 likert scale questions ranging from 1 to 5 with 1 being never and 5 being always. The HIT-6 answer options are weighted as follows: Never (1) = 6 points each, Rarely (2) = 9 points each, Sometimes (3) = 10 points each, Very often (4) = 11 points each, Always (5) = 13 points each. The total score for the HIT-6 ranges from 36 (subject answers all 6 questions as Never) to 78 subject answers all 6 questions as Always), with higher total scores indicating more impact than lower scores, i.e., headaches cause greater impact on the subject's life." (NCT01709708)
Timeframe: 10 Weeks

Migraine Headache Days

Intervention	units on a scale (Mean)
	Pre-Treatment	Post-Treatment	1-Month Post-Treatment
Marcaine	64.36	59.85	59.23
Saline	64	62.5	61.92

Compare change in the number of migraine headache days per month reported in Baseline Period Diary vs. Treatment Period Diary vs. Post-Treatment Period Diary. (NCT01709708)
Timeframe: 12 Weeks

Modified Pain Characteristic Questionnaire

Intervention	Migraine headache days per month (Mean)
	Baseline	Treatment	Post Treatment
Marcaine	15.0	12.3	10.8
Saline	15.8	12.2	11.3

Compare Modified Pain Characteristic Questionnaire scores Before Procedure vs. 24-Hour After Procedure, Before Procedure vs. 1-Month Follow Up, and Before Procedure vs. 6-Month Follow Up (Mean of all 12 treatments for each timepoint, comparing Group A to Group B). The modified pain characteristic questionnaire is a series of 11 questions on a likert scale ranging from 0 to 10 with 0 being no pain or does not interfere and 10 being worst pain or completely interferes. Percentage questions range from 0 to 100. (NCT01709708)
Timeframe: Before Treatment, 24 Hours After Treatment, 1 Month Post Treatment, and 6 Months Post Treatment

Numeric Rating Scale (NRS)

Intervention	units on a scale (Mean)
	Worst Pain Question: Before Treatment	Worst Pain Question: 24 Hours After Treatment	Worst Pain Question: 1 Month Post Treatment	Worst Pain Question: 6 Months Post Treatment	Least Pain Question: Before Treatment	Least Pain Question: 24 Hours After Treatment	Least Pain Question: 1 Month Post Treatment	Least Pain Question: 6 Months Post Treatment	Average Pain Question: Before Treatment	Average Pain Question: 24 Hours After Treatment	Average Pain Question: 1 Month Post Treatment	Average Pain Question: 6 Months Post Treatment	Percent Relief Question: Before Treatment	Percent Relief Question: 24 Hours After Treatment	Percent Relief Question: 1 Month Post Treatment	Percent Relief Question: 6 Months Post Treatment	General Activity Question: Before Treatment	General Activity Question: 24 Hours After Treatmen	General Activity Question: 1 Month Post Treatment	General Activity Question: 6 Months Post Treatment	Mood Interference Question: Before Treatment	Mood Interference Question: 24 Hours After Treatme	Mood Interference Question: 1 Month Post Treatment	Mood Interference Question: 6 Months Post Treatmen	Walking Ability Question: Before Treatment	Walking Ability Question: 24 Hours After Treatment	Walking Ability Question: 1 Month Post Treatment	Walking Ability Question: 6 Months Post Treatment	Normal Work Question: Before Treatment	Normal Work Question: 24 Hours After Treatment	Normal Work Question: 1 Month Post Treatment	Normal Work Question: 6 Months Post Treatment	Relationships Question: Before Treatment	Relationships Question: 24 Hours After Treatment	Relationships Question: 1 Month Post Treatment	Relationships Question: 6 Months Post Treatment	Sleep Interference Question: Before Treatment	Sleep Interfere Question: 24 Hours After Treatment	Sleep Interferenc Question: 1 Month Post Treatment	Sleep Interference Question: 6 Months Post Treatme	Enjoyment Question: Before Treatment	Enjoyment Question: 24 Hours After Treatment	Enjoyment Question: 1 Month Post Treatment	Enjoyment Question: 6 Months Post Treatment
Marcaine	4.75	4.36	4.56	4.27	2.01	1.77	1.88	1.68	3.39	3.07	3.36	2.86	41.3	46.0	46.3	34.7	2.49	2.31	2.64	2.68	2.57	2.42	2.96	3.18	0.63	0.54	0.80	0.45	2.53	2.21	2.52	2.59	2.00	1.96	2.36	2.05	2.29	1.89	1.92	1.55	2.81	2.58	2.64	3.18
Saline	6.15	6.16	5.64	5.88	2.50	2.43	2.64	2.88	4.33	4.27	3.91	4.00	29.2	29.8	21.0	18.6	3.50	3.64	3.91	4.00	3.78	4.19	3.82	5.71	1.27	1.24	0.55	0.43	3.49	3.63	3.45	3.71	3.47	3.90	3.09	3.86	2.68	2.85	2.55	3.14	3.12	3.34	3.09	4.00

Compare Numeric Rating Scale (NRS) scores Before Procedure,15-Minute Post Treatment, 30-Minutes Post Treatment, 24-Hour Post Treatment for all 12 treatments (Marcaine vs. Saline). NRS is a likert scale ranging from 0-10 with 0 being no pain and 10 being worst possible pain. For each individual time point, all 12 treatments were averaged for that time point and a single value was used for comparison between the two groups. (NCT01709708)
Timeframe: 6 Weeks

Overall Satisfaction

Intervention	units on a scale (Mean)
	Before Procedure	15 Minutes Post Treatment	30 Minutes Post Treatment	24 Hours Post Treatment
Marcaine	3.18	2.53	2.41	2.85
Saline	3.78	3.51	3.45	4.20

Satisfaction scores Visit 2 vs. following treatment (Treatment 12) and at 1-Month Post-Treatment (Group A vs. Group B). Satisfaction scores are a likert scale ranging from 1 to 5 with 1 being complete dissatisfaction and 5 being complete satisfaction. (NCT01709708)
Timeframe: 10 Weeks

Patient's Global Impression of Change (PGIC)

Intervention	units on a scale (Mean)
	Visit 2	Following treatment (Treatment 12)	1-Month Post-Treatment
Marcaine	3.52	3.55	3.57
Saline	3.00	2.50	2.64

Compare 24-Hour After Procedure Patient's Global Impression of Change (PGIC) score for 12 treatments (Mean of all 12 treatments for each timepoint, comparing Group A to Group B). PGIC is a likert scale ranging from 1 to 7 with 1 being very much improved and 7 being very much worse. (NCT01709708)
Timeframe: 30 minutes Post Treatment and 24 hours Post Treatment, assessed up to 6 weeks

Duration of Headache Free Period at 7 Days

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 28 Days

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 7 Days

Number of Participants With Injection Site Complication (Infection, Hematoma, and Ecchymosis)

Number of Participants With Need for Admission for Treatment of Headache

Number of Participants With Need for Crossover Treatment

Number of Participants With Need for Neurology Consult

Number of Participants With Need for Representation for Treatment of Headache With 28 Days

Intervention	units on a scale (Mean)
	30 Minutes Post Treatment	24 Hours Post Treatment
Marcaine	3.00	3.08
Saline	3.72	3.88

Intervention	days (Median)
Occipital Nerve Block	6
Oral Acetaminophen/Caffeine Group	1

Intervention	Participants (Count of Participants)
Occipital Nerve Block	9
Oral Acetaminophen/Caffeine Group	4

Intervention	Participants (Count of Participants)
Occipital Nerve Block	7
Oral Acetaminophen/Caffeine Group	2

Intervention	Participants (Count of Participants)
Occipital Nerve Block	0
Oral Acetaminophen/Caffeine Group	2

Intervention	Participants (Count of Participants)
Occipital Nerve Block	0
Oral Acetaminophen/Caffeine Group	0

Intervention	Participants (Count of Participants)
Occipital Nerve Block	9
Oral Acetaminophen/Caffeine Group	14

Intervention	Participants (Count of Participants)
Occipital Nerve Block	4
Oral Acetaminophen/Caffeine Group	2

Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days

Number of Participants With Need for Second Line Treatment

Number of Participants With Response to Occipital Nerve Block in Pregnancy

Intervention	Participants (Count of Participants)
Occipital Nerve Block	5
Oral Acetaminophen/Caffeine Group	1

Intervention	Participants (Count of Participants)
Occipital Nerve Block	5
Oral Acetaminophen/Caffeine Group	5

Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min

Response to Cross Over Treatment at 60 Min

Intervention	Participants (Count of Participants)
Occipital Nerve Block	20
Oral Acetaminophen/Caffeine Group	16

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min

Response to Second Line Treatment at 60 Min

Intervention	score on a scale (Median)
Occipital Nerve Block	6
Oral Acetaminophen/Caffeine Group	3

Response to Treatment Within 2 Hours

Article	Year
Celiac plexus block in the management of chronic abdominal pain. Current pain and headache reports, 2014, Volume: 18, Issue:2 Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea	2014
The needle and the brain: psychophysiological factors involved in nerve blocking for chronic pain. The Clinical journal of pain, 1991, Volume: 7, Issue:3 Topics: Autonomic Nerve Block; Bupivacaine; Chronic Disease; Humans; Nerve Block; Pain; Pain Management	1991
[Lumbar facet joint syndrome. Significance of non-organic signs. A randomized placebo-controlled clinical study]. Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1989, Volume: 75, Issue:7 Topics: Adult; Back Pain; Bupivacaine; Chronic Disease; Female; Follow-Up Studies; Humans; Injections; Injec	1989

Article	Year
Prospective, randomized, blinded, comparative study of injectable micronized dehydrated amniotic/chorionic membrane allograft for plantar fasciitis--a feasibility study. Foot & ankle international, 2013, Volume: 34, Issue:10 Topics: Allografts; Anesthetics, Local; Biological Dressings; Bupivacaine; Chronic Disease; Fasciitis, Plant	2013
A double-blind, placebo-controlled study of repetitive transnasal sphenopalatine ganglion blockade with tx360(®) as acute treatment for chronic migraine. Headache, 2015, Volume: 55, Issue:1 Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesth	2015
A double-blind, placebo-controlled study of repetitive transnasal sphenopalatine ganglion blockade with tx360(®) as acute treatment for chronic migraine. Headache, 2015, Volume: 55, Issue:1 Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesth	2015
A double-blind, placebo-controlled study of repetitive transnasal sphenopalatine ganglion blockade with tx360(®) as acute treatment for chronic migraine. Headache, 2015, Volume: 55, Issue:1 Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesth	2015
A double-blind, placebo-controlled study of repetitive transnasal sphenopalatine ganglion blockade with tx360(®) as acute treatment for chronic migraine. Headache, 2015, Volume: 55, Issue:1 Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesth	2015
Long-term efficacy of a double-blind, placebo-controlled, randomized study for repetitive sphenopalatine blockade with bupivacaine vs. saline with the Tx360 device for treatment of chronic migraine. Headache, 2015, Volume: 55, Issue:4 Topics: Adolescent; Adult; Aged; Anesthetics, Local; Bupivacaine; Catheterization; Chronic Disease; Double-B	2015
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7 Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe	2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7 Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe	2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7 Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe	2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7 Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe	2016
The efficacy of greater occipital nerve blockade in chronic migraine: A placebo-controlled study. Acta neurologica Scandinavica, 2017, Volume: 136, Issue:2 Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Double-Blind Method;	2017
The efficacy of greater occipital nerve blockade in chronic migraine: A placebo-controlled study. Acta neurologica Scandinavica, 2017, Volume: 136, Issue:2 Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Double-Blind Method;	2017
The efficacy of greater occipital nerve blockade in chronic migraine: A placebo-controlled study. Acta neurologica Scandinavica, 2017, Volume: 136, Issue:2 Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Double-Blind Method;	2017
The efficacy of greater occipital nerve blockade in chronic migraine: A placebo-controlled study. Acta neurologica Scandinavica, 2017, Volume: 136, Issue:2 Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Double-Blind Method;	2017
Chronic Whiplash Associated Disorders (WAD): Responses to Nerve Blocks of Cervical Zygapophyseal Joints. Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:12 Topics: Adult; Anesthetics, Local; Bupivacaine; Cervical Vertebrae; Chronic Disease; Double-Blind Method; Fe	2016
A prospective randomized trial of 1 versus 2 injections during EUS-guided celiac plexus block for chronic pancreatitis pain. Gastrointestinal endoscopy, 2009, Volume: 69, Issue:4 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Celiac Plexus; Chronic Disease; Endosonography; Female	2009
[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. Annales francaises d'anesthesie et de reanimation, 2010, Volume: 29, Issue:4 Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Body Temperature; Bupivacaine; Chronic Disease; Cough	2010
Stability and tolerability of high concentrations of intrathecal bupivacaine and opioid mixtures in chronic noncancer pain: an open-label pilot study. Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chromatography,	2010
The effect of local anaesthetic wound infiltration on chronic pain after lower limb joint replacement: a protocol for a double-blind randomised controlled trial. BMC musculoskeletal disorders, 2011, Feb-26, Volume: 12 Topics: Anesthetics, Local; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bupivacaine; Ch	2011
A pilot study of the dose-response of caudal methylprednisolone with levobupivacaine in chronic lower back pain. Anaesthesia, 2011, Volume: 66, Issue:7 Topics: Activities of Daily Living; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic	2011
Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain. International journal of pediatric otorhinolaryngology, 2012, Volume: 76, Issue:12 Topics: Adenoidectomy; Administration, Topical; Adolescent; Age Factors; Amides; Anesthetics, Local; Blood L	2012
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain. Annals of the rheumatic diseases, 2003, Volume: 62, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid;	2003
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain. Annals of the rheumatic diseases, 2003, Volume: 62, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid;	2003
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain. Annals of the rheumatic diseases, 2003, Volume: 62, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid;	2003
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain. Annals of the rheumatic diseases, 2003, Volume: 62, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid;	2003
Factors affecting the spread of bupivacaine in the adult thoracic paravertebral space. Anaesthesia, 2003, Volume: 58, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Administratio	2003
Factors affecting the spread of bupivacaine in the adult thoracic paravertebral space. Anaesthesia, 2003, Volume: 58, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Administratio	2003
Factors affecting the spread of bupivacaine in the adult thoracic paravertebral space. Anaesthesia, 2003, Volume: 58, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Administratio	2003
Factors affecting the spread of bupivacaine in the adult thoracic paravertebral space. Anaesthesia, 2003, Volume: 58, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Administratio	2003
[Evaluation of postoperative pain relief after video-assisted thoracoscopic surgery (VATS) for spontaneous pneumothorax]. Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:3 Topics: Adolescent; Adult; Bupivacaine; Chest Tubes; Chronic Disease; Female; Humans; Intercostal Nerves; Ma	2004
Suprascapular nerve block in chronic shoulder pain: are the radiologists better? Annals of the rheumatic diseases, 2004, Volume: 63, Issue:9 Topics: Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic Disease;	2004
Zygapophysial joint blocks in chronic low back pain: a test of Revel's model as a screening test. BMC musculoskeletal disorders, 2004, Nov-16, Volume: 5 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Humans; Injections, Intra-Art	2004
Modulation of central hypersensitivity by nociceptive input in chronic pain after whiplash injury. Pain medicine (Malden, Mass.), 2004, Volume: 5, Issue:4 Topics: Adult; Bupivacaine; Chronic Disease; Female; Humans; Hyperalgesia; Male; Middle Aged; Neck Muscles;	2004
The efficacy of corticosteroids in periradicular infiltration for chronic radicular pain: a randomized, double-blind, controlled trial. Spine, 2005, Apr-15, Volume: 30, Issue:8 Topics: Adult; Anesthetics, Local; Back Pain; Bupivacaine; Chronic Disease; Disability Evaluation; Double-Bl	2005
Cost-effectiveness and safety of epidural steroids in the management of sciatica. Health technology assessment (Winchester, England), 2005, Volume: 9, Issue:33 Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; C	2005
Therapeutic efficacy of facet joint blocks. AJR. American journal of roentgenology, 2006, Volume: 186, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Glucocorti	2006
Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy. Surgical endoscopy, 2006, Volume: 20, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cellulose, Oxidized; Cholecystectomy, Laparoscopic; Ch	2006
Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy. Surgical endoscopy, 2006, Volume: 20, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cellulose, Oxidized; Cholecystectomy, Laparoscopic; Ch	2006
Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy. Surgical endoscopy, 2006, Volume: 20, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cellulose, Oxidized; Cholecystectomy, Laparoscopic; Ch	2006
Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy. Surgical endoscopy, 2006, Volume: 20, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cellulose, Oxidized; Cholecystectomy, Laparoscopic; Ch	2006
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery. Anesthesia and analgesia, 2006, Volume: 103, Issue:4 Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Di	2006
Levator ani trigger point injections: An underutilized treatment for chronic pelvic pain. Neurourology and urodynamics, 2007, Volume: 26, Issue:1 Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anus Diseases; Bupivacaine; Chronic Disea	2007
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;	2008
Investigating the effect of intra-operative infiltration with local anaesthesia on the development of chronic postoperative pain after inguinal hernia repair. A randomized placebo controlled triple blinded and group sequential study design [NCT00484731]. BMC surgery, 2007, Nov-06, Volume: 7 Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Cross-Over Studies; Double-Blin	2007
Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints. The New England journal of medicine, 1994, Apr-14, Volume: 330, Issue:15 Topics: Adult; Anesthetics, Local; Betamethasone; Bupivacaine; Cervical Vertebrae; Chronic Disease; Double-B	1994
Comparative local anaesthetic blocks in the diagnosis of cervical zygapophysial joint pain. Pain, 1993, Volume: 55, Issue:1 Topics: Adult; Aged; Anesthetics, Local; Arthrography; Bupivacaine; Cervical Vertebrae; Chronic Disease; Dou	1993
Modified suprascapular nerve block with bupivacaine alone effectively controls chronic shoulder pain in patients with rheumatoid arthritis. Annals of the rheumatic diseases, 1993, Volume: 52, Issue:3 Topics: Adult; Aged; Arthritis, Rheumatoid; Bupivacaine; Chronic Disease; Double-Blind Method; Female; Human	1993
Prolongation of epidural bupivacaine analgesia with glycerin. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:5 Pt 1 Topics: Aged; Analgesia, Epidural; Bupivacaine; Chronic Disease; Delayed-Action Preparations; Female; Glycer	1993
Long term backache after childbirth: prospective search for causative factors. BMJ (Clinical research ed.), 1996, Jun-01, Volume: 312, Issue:7043 Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Back Pain; Bupivacaine; Chro	1996
Plasma concentrations of bupivacaine following single needle lumbar sympathectomy using two volumes of 0.25% bupivacaine plain solution. Anaesthesia, 1996, Volume: 51, Issue:8 Topics: Adult; Aged; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Female; Ganglia, Autonomic; Humans	1996
Intradiscal glycerol or bupivacaine in the treatment of low back pain. Acta neurochirurgica, 1997, Volume: 139, Issue:6 Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Cryoprotective Agents; Female; Glycerol; Hu	1997
Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder. Archives of physical medicine and rehabilitation, 1997, Volume: 78, Issue:11 Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Electromyography; Female; Humans; Isometric	1997
A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. The American journal of gastroenterology, 1999, Volume: 94, Issue:4 Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea	1999
A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. The American journal of gastroenterology, 1999, Volume: 94, Issue:4 Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea	1999
A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. The American journal of gastroenterology, 1999, Volume: 94, Issue:4 Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea	1999
A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. The American journal of gastroenterology, 1999, Volume: 94, Issue:4 Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea	1999
Bupivacaine instillation into gallbladder bed after laparoscopic cholecystectomy: does it decrease shoulder pain? Journal of laparoendoscopic & advanced surgical techniques. Part A, 2000, Volume: 10, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cholecystitis; Chronic Diseas	2000
Systemic alpha-adrenergic blockade with phentolamine: a diagnostic test for sympathetically maintained pain. Anesthesiology, 1991, Volume: 74, Issue:4 Topics: Adult; Bupivacaine; Chronic Disease; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Hemodyn	1991
[Lumbar facet joint syndrome. Significance of non-organic signs. A randomized placebo-controlled clinical study]. Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1989, Volume: 75, Issue:7 Topics: Adult; Back Pain; Bupivacaine; Chronic Disease; Female; Follow-Up Studies; Humans; Injections; Injec	1989

Article	Year
Suprascapular nerve block for the treatment of hemiplegic shoulder pain in patients with long-term chronic stroke: a pilot study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:9 Topics: Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Chronic Pain; Female; Functional Laterality;	2017
Successful treatment of paediatric lower limb CRPS by continuous epidural anaesthesia: a report of 2 cases. Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2018, Volume: 50, Issue:5 Topics: Adolescent; Adult; Analgesia, Epidural; Anesthesia, Epidural; Bupivacaine; Child; Chronic Disease; C	2018
The effects of spinal anaesthesia for elective caesarean section on uterine and umbilical arterial pulsatility indexes in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study. BMC pregnancy and childbirth, 2014, Aug-28, Volume: 14 Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Arterial Pressure; Blood Flow Velocity; Bupivacaine;	2014
[Effects of triple shoulder injection accompanied by fluoroscopy on pain experienced by patients with chronic shoulder pain]. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2014, Volume: 26, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic D	2014
Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients? Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:6 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Comorbidity; Female; Functional Later	2017
High volume image guided injections in chronic Achilles tendinopathy. Disability and rehabilitation, 2008, Volume: 30, Issue:20-22 Topics: Achilles Tendon; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic Disease;	2008
High volume ultrasound guided injections at the interface between the patellar tendon and Hoffa's body are effective in chronic patellar tendinopathy: A pilot study. Disability and rehabilitation, 2008, Volume: 30, Issue:20-22 Topics: Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic Disease; Follo	2008
Sources of sacroiliac region pain: insights gained from a study comparing standard intra-articular injection with a technique combining intra- and peri-articular injection. Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:11 Topics: Activities of Daily Living; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Therapy, Combinat	2008
Sources of sacroiliac region pain: insights gained from a study comparing standard intra-articular injection with a technique combining intra- and peri-articular injection. Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:11 Topics: Activities of Daily Living; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Therapy, Combinat	2008
Sources of sacroiliac region pain: insights gained from a study comparing standard intra-articular injection with a technique combining intra- and peri-articular injection. Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:11 Topics: Activities of Daily Living; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Therapy, Combinat	2008
Sources of sacroiliac region pain: insights gained from a study comparing standard intra-articular injection with a technique combining intra- and peri-articular injection. Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:11 Topics: Activities of Daily Living; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Therapy, Combinat	2008
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
"Scalp block" during craniotomy: a classic technique revisited. Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:3 Topics: Adult; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Contraindications; Craniotomy; Foreh	2010
Pneumorrhachis mimicking meningitis after a paramedian lumbar interlaminar injection. The Clinical journal of pain, 2011, Volume: 27, Issue:4 Topics: Aged; Back Pain; Bupivacaine; Chronic Disease; Female; Humans; Injections, Spinal; Intervertebral Di	2011
Use of ultrasound-guided subcostal transversus abdominis plane blocks in a pediatric patient with chronic abdominal wall pain. Paediatric anaesthesia, 2011, Volume: 21, Issue:1 Topics: Abdominal Cavity; Abdominal Pain; Adolescent; Anesthetics, Local; Bupivacaine; Chronic Disease; Fema	2011
[Hemicrania continua: characteristics and therapeutic experience in a series of 36 patients]. Revista de neurologia, 2012, Sep-01, Volume: 55, Issue:5 Topics: Adolescent; Adult; Age of Onset; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal;	2012
Percutaneous vertebroplasty in the management of a patient with malignant pain and associated osteolytic compression fractures. Current pain and headache reports, 2002, Volume: 6, Issue:6 Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Combined Modality Therapy; Female; Humans;	2002
Repeated peripheral nerve blocks by the co-administration of ketamine, morphine, and bupivacaine attenuate trigeminal neuralgia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2 Topics: Analgesics, Opioid; Anesthesia, Local; Anesthetics, Dissociative; Bupivacaine; Chronic Disease; Huma	2003
Chronic perineal pain caused by pudendal nerve entrapment: anatomy and CT-guided perineural injection technique. AJR. American journal of roentgenology, 2003, Volume: 181, Issue:2 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Glucocorticoids; Humans; Injections;	2003
Why CT-guided? AJR. American journal of roentgenology, 2004, Volume: 182, Issue:3 Topics: Anesthetics, Local; Bupivacaine; Chronic Disease; Glucocorticoids; Humans; Injections; Methylprednis	2004
Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions. BMC musculoskeletal disorders, 2004, May-28, Volume: 5 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Bupivacaine; Cervical Vertebrae; Chro	2004
Recurrent persistent hiccups after epidural steroid injection and analgesia with bupivacaine. Anesthesia and analgesia, 2005, Volume: 100, Issue:6 Topics: Aged; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Chronic	2005
Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis? The journal of pain, 2005, Volume: 6, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Plexus; Cervical Vertebrae; Chronic Disease;	2005
Repeated nerve blocks with clonidine, fentanyl and bupivacaine for trigeminal neuralgia. Anaesthesia, 2006, Volume: 61, Issue:1 Topics: Anesthetics; Bupivacaine; Chronic Disease; Clonidine; Electric Stimulation; Fentanyl; Humans; Nerve	2006
Sympathetically maintained pain presenting first as temporomandibular disorder, then as parotid dysfunction. Journal (Canadian Dental Association), 2007, Volume: 73, Issue:2 Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Autonomic Nervous System Diseases; Bupivacaine	2007
Learned helplessness and responses to nerve blocks in chronic low back pain patients. Pain, 1982, Volume: 14, Issue:4 Topics: Activities of Daily Living; Adult; Analgesics, Opioid; Autonomic Nerve Block; Back Pain; Bupivacaine	1982
Thoracic epidural analgesia for open cordotomy. Anesthesia and analgesia, 1984, Volume: 63, Issue:11 Topics: Aged; Anesthesia, Epidural; Bupivacaine; Chronic Disease; Cordotomy; Female; Humans; Pain Management	1984
Neurological factors in chronic pelvic pain: trigger points and the abdominal pelvic pain syndrome. American journal of obstetrics and gynecology, 1984, Jul-01, Volume: 149, Issue:5 Topics: Abdomen; Abdominal Muscles; Adolescent; Adult; Aged; Anesthesia, Local; Bupivacaine; Chronic Disease	1984
Caudal extradural injection for the treatment of low back pain. Anaesthesia, 1980, Volume: 35, Issue:5 Topics: Anesthesia, Caudal; Anesthesia, Epidural; Back Pain; Bupivacaine; Chronic Disease; Humans; Hydrocort	1980
Breaking the chronic pain cycle. The American journal of nursing, 1984, Volume: 84, Issue:10 Topics: Adult; Aged; Anesthesia, Local; Bupivacaine; Catheters, Indwelling; Child; Chronic Disease; Female;	1984
Continuous perineural infusion of bupivacaine for prolonged analgesia: pharmacokinetic considerations. International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:12 Topics: Brachial Plexus; Bupivacaine; Chronic Disease; Epidural Space; Humans; Injections; Kinetics; Lumbosa	1983
[Epidural opiates for relief of chronic pain (author's transl)]. Anesthesie, analgesie, reanimation, 1981, Volume: 38, Issue:7-8 Topics: Abdominal Neoplasms; Anesthesia, Epidural; Bupivacaine; Chronic Disease; Humans; Morphine; Narcotics	1981
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
A thermographic study of paravertebral analgesia. Anaesthesia, 1995, Volume: 50, Issue:2 Topics: Adult; Aged; Autonomic Nerve Block; Blood Pressure; Body Temperature; Bupivacaine; Chronic Disease;	1995
Intraarticular opioid-local anesthetic combinations for chronic joint pain. Middle East journal of anaesthesiology, 1994, Volume: 12, Issue:6 Topics: Adult; Aged; Analgesia; Arthralgia; Bupivacaine; Chronic Disease; Female; Humans; Injections, Intra-	1994
Interpleural catheter analgesia for chronic pain treatment--a case report. Middle East journal of anaesthesiology, 1994, Volume: 12, Issue:5 Topics: Abdominal Pain; Adenocarcinoma; Adult; Analgesia; Bupivacaine; Catheterization; Chronic Disease; Hum	1994
Use of liposome-associated bupivacaine for the management of a chronic pain syndrome. Anesthesia and analgesia, 1994, Volume: 79, Issue:4 Topics: Adult; Bupivacaine; Chronic Disease; Drug Carriers; Humans; Liposomes; Pain; Syndrome	1994
The stability of mixtures of morphine hydrochloride, bupivacaine hydrochloride, and clonidine hydrochloride in portable pump reservoirs for the management of chronic pain syndromes. Journal of pain and symptom management, 1994, Volume: 9, Issue:5 Topics: Bupivacaine; Chronic Disease; Clonidine; Drug Combinations; Drug Stability; Humans; Infusion Pumps;	1994
Epidural bupivacaine/sufentanil therapy for postoperative pain control in patients tolerant to opioid and unresponsive to epidural bupivacaine/morphine. Anesthesiology, 1994, Volume: 80, Issue:2 Topics: Abdomen; Adult; Analgesia, Epidural; Bupivacaine; Chronic Disease; Drug Tolerance; Female; Humans; M	1994
CT-guided injection of the stellate ganglion: description of technique and efficacy of sympathetic blockade. Radiology, 1993, Volume: 188, Issue:3 Topics: Adult; Autonomic Nerve Block; Bupivacaine; Buprenorphine; Chronic Disease; Female; Humans; Injection	1993
A comparison of postoperative epidural analgesia between patients with chronic cancer taking high doses of oral opioids versus opioid-naive patients. Anesthesia and analgesia, 1993, Volume: 76, Issue:2 Topics: Administration, Oral; Adult; Aged; Analgesia, Epidural; Bupivacaine; Chronic Disease; Female; Humans	1993
Cholestasis after interpleural bupivacaine for chronic upper limb pain. Anesthesia and analgesia, 1993, Volume: 76, Issue:5 Topics: Adult; Arm; Bupivacaine; Cholestasis; Chronic Disease; Female; Humans; Middle Aged; Pain; Pleura	1993
Chronic diarrhea: an uncommon side effect of celiac plexus block. Anesthesia and analgesia, 1996, Volume: 82, Issue:1 Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disease; Diarrhea; Ethanol; Female; Human	1996
Endosonography-guided celiac plexus injection for abdominal pain due to chronic pancreatitis. The American journal of gastroenterology, 1996, Volume: 91, Issue:8 Topics: Abdominal Pain; Adult; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chroni	1996
[Intrathecal administration of morphine and bupivacaine in the treatment of severe pain in chronic pancreatitis]. Nederlands tijdschrift voor geneeskunde, 1996, Jul-06, Volume: 140, Issue:27 Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chronic Disease; Humans; Infusion Pumps;	1996
Regional anesthesia in knee arthroscopy: a new technique involving femoral and sciatic nerve blocks in knee arthroscopy. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 1996, Volume: 12, Issue:1 Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Anterior Cruciate Ligament; Anterior Cruciate Lig	1996
Neurolytic thoracic paravertebral block in cancer pain. A clinical report. Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:5 Topics: Acute Disease; Adult; Aged; Analgesics; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Fo	1998
Local nerve blockade by bupivacaine reduced short- and long-term pain in children undergoing tonsillectomy and adenoidectomy. The Annals of otology, rhinology, and laryngology, 1998, Volume: 107, Issue:11 Pt 1 Topics: Acute Disease; Adenoidectomy; Anesthetics, Local; Bupivacaine; Child; Chronic Disease; Humans; Nerve	1998
Clinical experience using intrathecal (IT) bupivacaine infusion in three patients with complex regional pain syndrome type I (CRPS-I). Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:6 Topics: Adult; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Humans; Inject	1999
Identification of a new therapeutic approach for iliac crest donor site chronic pain: a case report. Anesthesia and analgesia, 1999, Volume: 89, Issue:6 Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bone Transplantation; Bupivacaine; Chro	1999
Open lateral sphincterotomy is still the best treatment for chronic anal fissure. American journal of surgery, 2000, Volume: 179, Issue:3 Topics: Ambulatory Surgical Procedures; Anal Canal; Anesthetics, Local; Bupivacaine; Chronic Disease; Fissur	2000
Spinal cord stimulation: a possible therapeutic alternative for chronic mesenteric ischaemia. Pain, 2000, Volume: 87, Issue:1 Topics: Abdominal Pain; Aged; Analgesics, Opioid; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Ce	2000
Long-term benefits of stellate ganglion block in severe chronic refractory angina. Pain, 2000, Volume: 87, Issue:1 Topics: Anesthetics, Local; Angina Pectoris; Autonomic Nerve Block; Bupivacaine; Chronic Disease; Humans; Ma	2000
Applications of intrathecal catheters in children. Paediatric anaesthesia, 2000, Volume: 10, Issue:4 Topics: Adenocarcinoma; Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics	2000
MRI-guided celiac plexus block. Journal of magnetic resonance imaging : JMRI, 2000, Volume: 12, Issue:4 Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disease; Female; Humans;	2000
Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin. Neuroscience, 2000, Volume: 101, Issue:4 Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Chronic Disease; Dose-Response Relations	2000
Endoscopic ultrasound-guided celiac plexus block for managing abdominal pain associated with chronic pancreatitis: a prospective single center experience. The American journal of gastroenterology, 2001, Volume: 96, Issue:2 Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disease; Costs and Cost A	2001
Cephalic spreading levels after volumetric caudal epidural injections in chronic low back pain. Journal of Korean medical science, 2001, Volume: 16, Issue:2 Topics: Adult; Aged; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Fluoros	2001
Inefficacy of high-dose transdermal fentanyl in a patient with neuropathic pain, a case report. European journal of pain (London, England), 2001, Volume: 5, Issue:3 Topics: Administration, Cutaneous; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Breast Neopl	2001
Stability, compatibility, and safety of intrathecal bupivacaine administered chronically via an implantable delivery system. The Clinical journal of pain, 2001, Volume: 17, Issue:3 Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Chronic Disease; Drug Deliv	2001
Practice tips. Treating persistent cough. Try a nebulized mixture of lidocaine and bupivacaine. Canadian family physician Medecin de famille canadien, 2002, Volume: 48 Topics: Administration, Inhalation; Anesthetics, Local; Bupivacaine; Chronic Disease; Cough; Humans; Lidocai	2002
Successful treatment of restless legs syndrome with an implanted pump for intrathecal drug delivery. Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:1 Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chronic Disease; Fem	2002
Chronic pain syndromes and their treatment. III. The piriformis syndrome. Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4 Topics: Adult; Anesthetics, Local; Back Pain; Bupivacaine; Chronic Disease; Diagnosis, Differential; Female;	1979
Epidural anesthesia following thoracotomy in patients with chronic obstructive airway disease. The Journal of thoracic and cardiovascular surgery, 1976, Volume: 71, Issue:1 Topics: Aged; Anesthesia, Epidural; Bupivacaine; Chronic Disease; Epinephrine; Humans; Lung Diseases, Obstru	1976
Long-term interpleural analgesia using a subcutaneous implantable infusion system. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:4 Topics: Analgesia; Bupivacaine; Chest Pain; Chronic Disease; Humans; Infusion Pumps, Implantable; Male; Midd	1992
Chronic headache resulting from postoperative supraorbital neuralgia. Anesthesia and analgesia, 1992, Volume: 74, Issue:6 Topics: Bupivacaine; Chronic Disease; Headache; Humans; Nerve Block; Neuralgia; Orbit; Postoperative Complic	1992
Intermittent interpleural injection of bupivacaine and methylprednisolone for analgesia in metastatic thoracic neoplasm. The Clinical journal of pain, 1991, Volume: 7, Issue:3 Topics: Breast Neoplasms; Bupivacaine; Carcinoma, Small Cell; Chronic Disease; Female; Humans; Lung Neoplasm	1991
Chronic headache resulting from postoperative supraorbital neuralgia. Anesthesia and analgesia, 1991, Volume: 73, Issue:4 Topics: Bupivacaine; Chronic Disease; Clonazepam; Female; Headache; Humans; Middle Aged; Nerve Block; Neural	1991
Exaggerated epidural blockade resulting from unusual spread of bupivacaine in a patient with low back pain. Anaesthesia, 1991, Volume: 46, Issue:10 Topics: Aged; Anesthesia, Epidural; Back Pain; Bupivacaine; Chronic Disease; Contrast Media; Female; Humans;	1991
Treatment of benign chronic abdominal pain with neurolytic celiac plexus block. Anesthesiology, 1991, Volume: 75, Issue:1 Topics: Abdominal Pain; Adult; Bupivacaine; Celiac Plexus; Chronic Disease; Female; Humans; Lidocaine; Nerve	1991
Extradural abscess following local anaesthetic and steroid injection for chronic low back pain. British journal of anaesthesia, 1990, Volume: 65, Issue:3 Topics: Abscess; Aged; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Bupivacaine; Chronic Disease; Di	1990
Treatment of pancreatic pain with interpleural bupivacaine: an open trial. Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:2 Topics: Adult; Bupivacaine; Catheters, Indwelling; Chronic Disease; Female; Humans; Male; Middle Aged; Pain;	1990
Superior hypogastric plexus block for pelvic cancer pain. Anesthesiology, 1990, Volume: 73, Issue:2 Topics: Abdominal Pain; Adult; Analgesia, Epidural; Bupivacaine; Chronic Disease; Female; Fluoroscopy; Human	1990
[Interpleural bupivacaine (Marcain) in the treatment of pain in a patient with chronic pancreatitis]. Ugeskrift for laeger, 1989, Nov-20, Volume: 151, Issue:47 Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Humans; Male; Nerve Block; Pancreatitis; Pl	1989
[Continuous intercostal nerve block for chronic pain]. Harefuah, 1989, May-01, Volume: 116, Issue:9 Topics: Acute Disease; Adult; Aged; Bupivacaine; Chest Pain; Chronic Disease; Female; Follow-Up Studies; Hum	1989
Chronic paroxysmal hemicrania. X. On the autonomic involvement. Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:2 Topics: Atropine; Autonomic Nerve Block; Autonomic Nervous System; Bupivacaine; Chronic Disease; Cornea; Fem	1986
The roles of acute and chronic pain in regression of sensory analgesia during continuous epidural bupivacaine infusion. Anesthesia and analgesia, 1988, Volume: 67, Issue:8 Topics: Aged; Analgesia; Bupivacaine; Chronic Disease; Epidural Space; Female; Humans; Male; Middle Aged; Pa	1988
Paraplegia following epidural potassium chloride. Anaesthesia, 1985, Volume: 40, Issue:1 Topics: Adult; Anesthesia, Epidural; Bupivacaine; Chronic Disease; Female; Humans; Medication Errors; Morphi	1985

bupivacaine and Chronic Illness