bupivacaine has been researched along with Cerebral Palsy in 6 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 9.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| "To compare diazepam use, muscle spasm, analgesia, and side effects when clonidine or fentanyl are added to epidural bupivacaine in children with cerebral palsy after multilevel orthopaedic surgery." | 9.22 | Comparison of lumbar epidural bupivacaine with fentanyl or clonidine for postoperative analgesia in children with cerebral palsy after single-event multilevel surgery. ( Chalkiadis, GA; Dowden, SJ; Graham, HK; Low, J; Orsini, F; Penrose, S; Pirpiris, M; Sommerfield, D; Tay, M, 2016) |
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 5.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| "To compare diazepam use, muscle spasm, analgesia, and side effects when clonidine or fentanyl are added to epidural bupivacaine in children with cerebral palsy after multilevel orthopaedic surgery." | 5.22 | Comparison of lumbar epidural bupivacaine with fentanyl or clonidine for postoperative analgesia in children with cerebral palsy after single-event multilevel surgery. ( Chalkiadis, GA; Dowden, SJ; Graham, HK; Low, J; Orsini, F; Penrose, S; Pirpiris, M; Sommerfield, D; Tay, M, 2016) |
| "A child with cerebral palsy and carnitine deficiency developed ventricular arrhythmias with loss of cardiac output during elective surgery under general anaesthesia with concomitant epidural analgesia." | 3.76 | Lipid resuscitation in a carnitine deficient child following intravascular migration of an epidural catheter. ( Joo, DT; McDonnell, C; Wong, GK, 2010) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "Pruritus was observed in 29% of patients and was more common in diplegia than quadriplegia (48% vs 12." | 1.30 | Epidural analgesia in children with cerebral palsy. ( Brenn, BR; Brislin, RP; Rose, JB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chalkiadis, GA | 2 |
| Sommerfield, D | 1 |
| Low, J | 1 |
| Orsini, F | 1 |
| Dowden, SJ | 1 |
| Tay, M | 1 |
| Penrose, S | 1 |
| Pirpiris, M | 1 |
| Graham, HK | 1 |
| Ozkan, D | 1 |
| Gonen, E | 1 |
| Akkaya, T | 1 |
| Bakir, M | 1 |
| Wong, GK | 1 |
| Joo, DT | 1 |
| McDonnell, C | 1 |
| Skinner, AV | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Brenn, BR | 1 |
| Brislin, RP | 1 |
| Rose, JB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Postoperative Pain Management in Pediatric Patients With Cerebral Palsy - Comparative Observational Study"[NCT05252650] | 130 participants (Anticipated) | Observational | 2022-02-15 | Recruiting | |||
| Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy[NCT02507700] | 60 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for bupivacaine and Cerebral Palsy
4 other studies available for bupivacaine and Cerebral Palsy
| Article | Year |
|---|---|
Lipid resuscitation in a carnitine deficient child following intravascular migration of an epidural catheter.
Topics: Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Carnitine; Cerebral Palsy; Child; Fat Emulsion | 2010 |
Clinically unrecognized intravascular placement of epidural catheter in a child--an argument for the use of radio-opaque contrast?
Topics: Adrenergic Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Local; Blood Pressure; Bupivacain | 2007 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
Epidural analgesia in children with cerebral palsy.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cerebral Palsy; Child; Con | 1998 |