bupivacaine has been researched along with Cartilage Diseases in 18 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Cartilage Diseases: Pathological processes involving the chondral tissue (CARTILAGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postoperative knee chondrolysis caused by continuous intra-articular pain pumps infusing bupivacaine with epinephrine is a rare but serious complication." | 7.81 | Knee chondrolysis by infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter after arthroscopic ACL reconstruction. ( Buchko, JZ; Gurney-Dunlop, T; Shin, JJ, 2015) |
| "Postoperative knee chondrolysis caused by continuous intra-articular pain pumps infusing bupivacaine with epinephrine is a rare but serious complication." | 3.81 | Knee chondrolysis by infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter after arthroscopic ACL reconstruction. ( Buchko, JZ; Gurney-Dunlop, T; Shin, JJ, 2015) |
| " The effects of local anaesthetics on equine chondrocytes are mixed with some studies reporting chondrodestruction and others no adverse effects." | 2.90 | Plasma and synovial fluid concentrations and cartilage toxicity of bupivacaine following intra-articular administration of a liposomal formulation to horses. ( Hill, AE; Knych, HK; Mama, KR; McKEMIE, DS; Moore, CE, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knych, HK | 1 |
| Mama, KR | 1 |
| Moore, CE | 1 |
| Hill, AE | 1 |
| McKEMIE, DS | 1 |
| Matsen, FA | 2 |
| Papadonikolakis, A | 1 |
| Hasan, SS | 3 |
| Fleckenstein, CM | 3 |
| Buchko, JZ | 2 |
| Gurney-Dunlop, T | 1 |
| Shin, JJ | 1 |
| Webb, ST | 1 |
| Ghosh, S | 1 |
| Busfield, BT | 1 |
| Romero, DM | 1 |
| White, SM | 1 |
| Turner, R | 1 |
| McNaught, AF | 1 |
| McCartney, C | 1 |
| Anakwenze, OA | 1 |
| Hosalkar, H | 1 |
| Huffman, GR | 1 |
| Anderson, SL | 1 |
| Taillon, MR | 1 |
| Ernst, MA | 1 |
| Levy, M | 1 |
| Noyes, FR | 2 |
| Moller, SA | 1 |
| Zambelli-Weiner, A | 1 |
| Beck, CL | 1 |
| Townsley, R | 1 |
| Beck, EP | 1 |
| Hansen, B | 1 |
| Levine, WN | 1 |
| Wiater, BP | 1 |
| Neradilek, MB | 1 |
| Polissar, NL | 1 |
| Serrato, JA | 1 |
| Piper, SL | 1 |
| Kim, HT | 1 |
| Barber-Westin, SD | 1 |
| Burks, RT | 1 |
| Gomoll, AH | 1 |
| Kang, RW | 1 |
| Williams, JM | 1 |
| Bach, BR | 1 |
| Cole, BJ | 1 |
2 reviews available for bupivacaine and Cartilage Diseases
| Article | Year |
|---|---|
Published evidence demonstrating the causation of glenohumeral chondrolysis by postoperative infusion of local anesthetic via a pain pump.
Topics: Adult; Anesthetics, Local; Arthroplasty, Replacement; Bupivacaine; Cartilage Diseases; Cartilage, Ar | 2013 |
Pain pump use after shoulder arthroscopy as a cause of glenohumeral chondrolysis.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Analgesia, Patient-Controlled; Anesthetics, Local; Animals | 2009 |
1 trial available for bupivacaine and Cartilage Diseases
| Article | Year |
|---|---|
Plasma and synovial fluid concentrations and cartilage toxicity of bupivacaine following intra-articular administration of a liposomal formulation to horses.
Topics: Animals; Area Under Curve; Bupivacaine; Cartilage Diseases; Drug Compounding; Half-Life; Horse Disea | 2019 |
15 other studies available for bupivacaine and Cartilage Diseases
| Article | Year |
|---|---|
Glenohumeral chondrolysis: part I--clinical presentation and predictors of disease progression.
Topics: Adolescent; Adult; Anesthetics, Local; Arthralgia; Arthroscopy; Bupivacaine; Cartilage Diseases; Car | 2013 |
Knee chondrolysis by infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter after arthroscopic ACL reconstruction.
Topics: Adolescent; Adult; Anesthetics, Local; Anterior Cruciate Ligament Reconstruction; Arthralgia; Arthro | 2015 |
Intra-articular bupivacaine: potentially chondrotoxic?
Topics: Anesthetics, Local; Arthroscopy; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Humans; Inje | 2009 |
Bupivacaine chondrotoxicity.
Topics: Anesthetics, Local; Bupivacaine; Cartilage Diseases; Humans; Injections, Intra-Articular; Pain, Post | 2009 |
Bupivacaine chondrotoxicity.
Topics: Anesthetics, Local; Bupivacaine; Cartilage Diseases; Humans; Injections, Intra-Articular; Pain, Post | 2009 |
Case reports: two cases of glenohumeral chondrolysis after intraarticular pain pumps.
Topics: Adult; Analgesia; Anesthetics, Local; Arthroscopy; Bupivacaine; Cartilage Diseases; Cartilage, Artic | 2010 |
Chondrolysis of the glenohumeral joint after infusion of bupivacaine through an intra-articular pain pump catheter: a report of 18 cases.
Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Cathet | 2010 |
Letter to the editor.
Topics: Anesthetics, Local; Arthroscopy; Bupivacaine; Cartilage Diseases; Chondrocytes; Cohort Studies; Epin | 2010 |
Commentary on an article by Brett P. Wiater, MD, et al.: "Risk factors for chondrolysis of the glenohumeral joint. A study of three hundred and seventy-five shoulder arthroscopic procedures in the practice of an individual community surgeon".
Topics: Arthroscopy; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Cohort Studies; Databases, Factu | 2011 |
Risk factors for chondrolysis of the glenohumeral joint: a study of three hundred and seventy-five shoulder arthroscopic procedures in the practice of an individual community surgeon.
Topics: Adult; Age Distribution; Aged; Arthroscopy; Bupivacaine; Cartilage Diseases; Cartilage, Articular; C | 2011 |
Glenohumeral chondrolysis associated with use of an intra-articular pain pump delivering local anesthetics following manipulation under anesthesia: a report of four cases.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Combin | 2011 |
Thermal stress potentiates bupivacaine chondrotoxicity.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Cattle; Cell Sur | 2012 |
The development of postoperative knee chondrolysis after intra-articular pain pump infusion of an anesthetic medication: a series of twenty-one cases.
Topics: Adolescent; Adult; Arthralgia; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Drug Combinati | 2012 |
Chondrolysis is not just a shoulder problem anymore: commentary on an article by Frank R. Noyes, MD, et al.: “The development of postoperative knee chondrolysis after intra-articular pain pump infusion of an anesthetic medication. A series of twenty-one c
Topics: Bupivacaine; Cartilage Diseases; Female; Humans; Injections, Intra-Articular; Knee Injuries; Male; P | 2012 |
Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Animals; Bupivacaine; Cartilage Diseases; Cartila | 2006 |