Page last updated: 2024-10-24

bupivacaine and Cancer of Endometrium

bupivacaine has been researched along with Cancer of Endometrium in 2 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"We enrolled endometrial cancer patients undergoing open abdominal hysterectomy with lymphadenectomy by the same surgeon."1.40Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy. ( Jennings, PW; Santoso, JT; Ulm, MA; Wan, JY, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santoso, JT1
Ulm, MA1
Jennings, PW1
Wan, JY1
Mercadante, S1
Villari, P1
Ferrera, P1
Arcuri, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multimodal Pain Management for Cesarean Delivery: A Randomized Control Trial[NCT02922985]Phase 4120 participants (Actual)Interventional2016-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Apgar Score at 5 Minutes

This is the Apgar score of the newborn collected at 5 minutes. Range is from 0-10, with the higher scores meaning a better outcome. (NCT02922985)
Timeframe: 5 minutes after birth

Interventionscore on a scale (Median)
Placebo Control Group9
Multimodal Pain Regimen Group9

Hospital Length of Stay

Time to discharge from hospital, measured in hours (NCT02922985)
Timeframe: From time of hospital admission to time of discharge home up to 168 hours.

Interventionhours (Median)
Placebo Control Group50.2
Multimodal Pain Regimen Group50

Need for Respiratory Support

neonate receipt of oxygen by nasal cannula or mechanical ventilation (NCT02922985)
Timeframe: after birth and before hospital discharge

InterventionParticipants (Count of Participants)
Placebo Control Group0
Multimodal Pain Regimen Group4

NICU Admission

Rate of admission to the neonatal intensive care unit (NCT02922985)
Timeframe: after birth and before hospital discharge

InterventionParticipants (Count of Participants)
Placebo Control Group2
Multimodal Pain Regimen Group6

Number of Opioid Pain Tablets Remaining on Post-operative Day #7 From the Discharge Prescription.

Number of opioid pain tablets remaining on post-operative day #7 from hospital discharge as reported by patients (NCT02922985)
Timeframe: 7 days post delivery

InterventionTablets (Median)
Placebo Control Group18
Multimodal Pain Regimen Group19

Pain Score at 24 Hours Post-operatively

Pain Score at 24 Hours Post Operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 24 hours post-operatively

Interventionscore on a scale (Median)
Placebo Control Group5
Multimodal Pain Regimen Group6

Pain Score at 48 Hours Post-operatively

Pain Score at 48 Hours Post-operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 48 hours post-operatively

Interventionscore on a scale (Median)
Placebo Control Group4
Multimodal Pain Regimen Group3

Pain Score at 6-12 Hours Post Operatively

Pain score at 6-12 hours post-operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 6-12 hours post-operatively

Interventionscore on a scale (Median)
Placebo Control Group6
Multimodal Pain Regimen Group6

Time to First Administration of Opioid Pain Medication Post Operatively

Time, in hours, to first administration of opioid pain medication post operatively (NCT02922985)
Timeframe: 48 hours post cesarean delivery

Interventionhours (Median)
Placebo Control Group6.05
Multimodal Pain Regimen Group6.35

Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD)

Every opioid intake by the patient in the first 48 hours after CD will be recorded and quantified in morphine milligram equivalents (NCT02922985)
Timeframe: 48 hours post cesarean delivery

Interventionmorphine milligram equivalents (Median)
Placebo Control Group42
Multimodal Pain Regimen Group49.5

Other Studies

2 other studies available for bupivacaine and Cancer of Endometrium

ArticleYear
Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 183

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Bupivacaine; Cohort S

2014
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans

2003