bupivacaine and Cancer of Colon studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

Excerpt	Relevance	Reference
"Human colon cancer cells and human melanoma cells were cultured and then treated with 1 mM bupivacaine or levobupivacaine for up to 24 or 48 h."	7.91	Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. ( Chen, L; Han, C; Hirota, K; Li, T; Ma, D; Masters, J; Wu, L; Zhao, H, 2019)
"Human colon cancer cells and human melanoma cells were cultured and then treated with 1 mM bupivacaine or levobupivacaine for up to 24 or 48 h."	3.91	Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. ( Chen, L; Han, C; Hirota, K; Li, T; Ma, D; Masters, J; Wu, L; Zhao, H, 2019)
" Despite leptomeningeal infection during prolonged treatment, epidural analgesia at the lumbar level provided analgesia using very large doses of local anesthetics combined with clonidine and morphine."	3.72	Epidural analgesia at end of life: facing empirical contraindications. ( Eikermann, M; Exner, HJ; Peters, J, 2003)
"In a 32 years old patient with advanced gastric cancer epidural analgesia with local anaesthetic and morphine via a thoracic epidural catheter was required because of intractable pain and intolerable side effects of intravenous morphine."	3.69	[Conversion from peridural to transdermal opiate analgesia in abdominal tumor pain syndrome]. ( Fösel, T; Gaiser, H; Müller, R; Schuler, M, 1997)
"Postoperative pain was assessed by visual analogue scale and analgesic usage."	2.80	Infiltration of Local Anesthesia at Wound Site after Single-Incision Laparoscopic Colectomy Reduces Postoperative Pain and Analgesic Usage. ( Chang, CL; Chen, HH; Lee, KC; Lin, SE; Lu, CC, 2015)
"Mechanical hyperalgesia was measured by von Frey filaments."	2.71	The short-lasting analgesia and long-term antihyperalgesic effect of intrathecal clonidine in patients undergoing colonic surgery. ( De Kock, M; Lavand'homme, P; Waterloos, H, 2005)
"Mild hypothermia is accompanied by metabolic changes."	2.69	Metabolic changes during recovery in normothermic versus hypothermic patients undergoing surgery and receiving general anesthesia and epidural local anesthetic agents. ( Carli, F; Edwardes, M; Klubien, K; Mazza, L; Motamed, S, 1998)
"A 48-year-old woman, diagnosed as colon cancer with metastases in the liver, lung, bone and left rectus abdominis, developed refractory left abdominal pain in spite of escalating administration of opioids and nerve block therapy, and intrathecal analgesia was applied."	1.35	[Intrathecal segmental analgesia with a single dose of bupivacaine for cancer pain in the abdominal wall]. ( Chigusa, S; Ikegaki, J; Kaetsu, H; Kato, H; Kurihara, Y, 2008)

Research

Studies (15)

Authors

Clinical Trials (7)

Trial Overview

Trial Outcomes

Cost of Surgical Therapy

CRP

Length of Hospitalization Post-operation

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.67)	18.7374
1990's	5 (33.33)	18.2507
2000's	5 (33.33)	29.6817
2010's	4 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Urits, I	1
Petro, J	1
Viswanath, O	1
Aner, M	1
Li, T	1
Chen, L	1
Zhao, H	1
Wu, L	1
Masters, J	1
Han, C	1
Hirota, K	1
Ma, D	1
Lee, KC	1
Lu, CC	1
Lin, SE	1
Chang, CL	1
Chen, HH	1
Wolthuis, AM	1
Penninckx, F	1
Fieuws, S	1
D'Hoore, A	1
Exner, HJ	1
Peters, J	1
Eikermann, M	1
De Kock, M	1
Lavand'homme, P	1
Waterloos, H	1
Kurihara, Y	1
Ikegaki, J	1
Kato, H	1
Chigusa, S	1
Kaetsu, H	1
Bardram, L	1
Funch-Jensen, P	1
Jensen, P	1
Crawford, ME	1
Kehlet, H	1
Schuler, M	1
Gaiser, H	1
Müller, R	1
Fösel, T	1
Motamed, S	1
Klubien, K	1
Edwardes, M	1
Mazza, L	1
Carli, F	1
Furuya, R	1
Hirai, A	1
Andoh, T	1
Kudoh, I	1
Okumura, F	1
Lahav, M	1
Levite, M	1
Bassani, L	1
Lang, A	1
Fidder, H	1
Tal, R	1
Bar-Meir, S	1
Mayer, L	1
Chowers, Y	1
Henriksen, MG	1
Hansen, HV	1
Hessov, I	1
Kopacz, DJ	1
Ehring, E	1
Boekstegers, A	1

Trial	Enrollment	Study Type	Start Date	Status
Randomized Clinical Trial Comparing the Use of Perioperative Epidural Analgesia to Conventional Intravenous Narcotics and NSAIDS for Patients Undergoing Laparoscopic Colorectal Resection[NCT02086123]	87 participants (Actual)	Interventional	2012-05-31	Completed
Randomized Controlled Trial Assessing the Value of Prehabilitation in Patients Undergoing Colorectal Surgery According to the ERAS Protocol for the Improvement of Postoperative Outcomes[NCT02746731]	112 participants (Actual)	Interventional	2016-06-30	Completed
Clinical and Economical Evaluation of Colorectal Surgery in Ambulatory Care[NCT03760939]	140 participants (Anticipated)	Interventional	2019-01-03	Recruiting
ERAS Lazio Network Clinical Registry[NCT03353311]	1,000 participants (Actual)	Observational [Patient Registry]	2014-09-01	Completed
Fast-track Surgery After Gynaecological Oncological Surgery[NCT02687412]	107 participants (Actual)	Interventional	2016-11-21	Completed
Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy (iPEP Study) A Prospective Randomized-controlled Pilot Trial[NCT02478996]	80 participants (Anticipated)	Interventional	2015-08-31	Recruiting
Impact on the Hospital Stay, of an Early Oral Nutrition Protocol Applied to Gastric Cancer Patients After Total Gastrectomy: A Prospective Randomized Control Trial (DOPGT_2015)[NCT03257280]	84 participants (Anticipated)	Interventional	2017-10-20	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Intervention	RMB (Mean)
Fast-track Surgery	9703.22
Traditional Surgery	9538.47

Intervention	mg/L (Mean)
Fast-track Surgery	42.125
Traditional Surgery	62.499

days from operation date to discharge date (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Complications

Intervention	days (Mean)
Fast-track Surgery	8.92
Traditional Surgery	9.67

Count of patients with complications in both groups are assessed during the first 21 days postoperatively. Including infection(wound infection, lung infection, intraperitoneal infection, operation space infection), postoperative nausea and vomiting (PONV) , ileus, postoperative hemorrhage, postoperative thrombosis. (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Ileus

Intervention	Participants (Count of Participants)
Fast-track Surgery	3
Traditional Surgery	13

is a disruption of the normal propulsive ability of the gastrointestinal tract (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Infection,

Intervention	Participants (Count of Participants)
Fast-track Surgery	1
Traditional Surgery	1

infection(wound infection, lung infection, intraperitoneal infection, operation space infection) (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Postoperative Haemorrhage

Intervention	Participants (Count of Participants)
Fast-track Surgery	2
Traditional Surgery	12

Evidence of blood loss from drains or based on ultrasonography (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Postoperative Nausea and Vomiting (PONV)

Intervention	Participants (Count of Participants)
Fast-track Surgery	0
Traditional Surgery	0

it was recognized that nausea and vomiting are common side effects of surgical recovery (NCT02687412)
Timeframe: up to 12 months

Number of Participants With Postoperative Thrombosis

Intervention	Participants (Count of Participants)
Fast-track Surgery	0
Traditional Surgery	0

Evidence of blood thrombosis of participants after surgery (NCT02687412)
Timeframe: up to 12 months

Article	Year
Infiltration of Local Anesthesia at Wound Site after Single-Incision Laparoscopic Colectomy Reduces Postoperative Pain and Analgesic Usage. Hepato-gastroenterology, 2015, Volume: 62, Issue:140 Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Colectomy; Colonic Neoplasms; Fema	2015
The short-lasting analgesia and long-term antihyperalgesic effect of intrathecal clonidine in patients undergoing colonic surgery. Anesthesia and analgesia, 2005, Volume: 101, Issue:2 Topics: Adrenergic alpha-Agonists; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anest	2005
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Metabolic changes during recovery in normothermic versus hypothermic patients undergoing surgery and receiving general anesthesia and epidural local anesthetic agents. Anesthesiology, 1998, Volume: 88, Issue:5 Topics: Aged; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Blo	1998

Article	Year
Retrograde placement of an intrathecal catheter for chronic low pelvic cancer pain. Journal of clinical anesthesia, 2019, Volume: 54 Topics: Bupivacaine; Cancer Pain; Catheterization; Chronic Pain; Colonic Neoplasms; Fluoroscopy; Humans; Hyd	2019
Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. Journal of anesthesia, 2019, Volume: 33, Issue:1 Topics: Anesthetics, Local; Apoptosis; Bupivacaine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms;	2019
Outcomes for case-matched single-port colectomy are comparable with conventional laparoscopic colectomy. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012, Volume: 14, Issue:5 Topics: Adenoma; Adult; Aged; Analgesics; Blood Loss, Surgical; Bupivacaine; C-Reactive Protein; Colectomy;	2012
Epidural analgesia at end of life: facing empirical contraindications. Anesthesia and analgesia, 2003, Volume: 97, Issue:6 Topics: Abdominal Pain; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Analgesics, Opioid; Anestheti	2003
[Intrathecal segmental analgesia with a single dose of bupivacaine for cancer pain in the abdominal wall]. Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:2 Topics: Abdominal Neoplasms; Abdominal Pain; Abdominal Wall; Analgesia, Epidural; Bupivacaine; Colonic Neopl	2008
[Conversion from peridural to transdermal opiate analgesia in abdominal tumor pain syndrome]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1997, Volume: 32, Issue:5 Topics: Adult; Analgesia, Epidural; Bupivacaine; Carcinoma, Signet Ring Cell; Colonic Neoplasms; Combined Mo	1997
Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia. Anesthesiology, 1998, Volume: 89, Issue:1 Topics: Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiparkinson Agents; Bupivacaine; Colonic Neopl	1998
Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells. Clinical and experimental immunology, 2002, Volume: 127, Issue:2 Topics: Adenocarcinoma; Anesthetics, Local; Bupivacaine; Colitis, Ulcerative; Colonic Neoplasms; Epithelial	2002
Early oral nutrition after elective colorectal surgery: influence of balanced analgesia and enforced mobilization. Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:3 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Colonic Neoplasms; Co	2002
Continuous spinal anaesthesia for abdominal surgery in a patient receiving amiodarone. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:3 Topics: Adenocarcinoma; Amiodarone; Anesthesia, Spinal; Arrhythmias, Cardiac; Bupivacaine; Colon; Colonic Ne	1991
[Morphologic and histologic changes caused by continuous peridural analgesia in a cancer patient]. Regional-Anaesthesie, 1986, Volume: 9, Issue:2 Topics: Adenocarcinoma; Anesthesia, Epidural; Bupivacaine; Catheters, Indwelling; Colonic Neoplasms; Fentany	1986

bupivacaine and Cancer of Colon