Page last updated: 2024-10-23

bupivacaine and Brain Neoplasms

bupivacaine has been researched along with Brain Neoplasms in 8 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"5% bupivacaine was associated with lower intraoperative and postoperative visual analog scale pain scores."4.31Wide Awake Local Anesthesia No Tourniquet Technique in Hand Surgery: The Patient Experience. ( Cusano, A; Ferreira, J; LeVasseur, MR; Olivieri-Ortiz, R; Parrino, A; Pina, M, 2023)
"Serial arterial plasma levobupivacaine concentrations following scalp blockade were measured to 2 h in 10 patients booked for awake craniotomy for epilepsy or tumour surgery."3.73Plasma levobupivacaine concentrations following scalp block in patients undergoing awake craniotomy. ( Cormack, JR; Costello, TG; Harris, K; LaFerlita, B; Mather, LE; Murphy, MA, 2005)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Pina, M1
Cusano, A1
LeVasseur, MR1
Olivieri-Ortiz, R1
Ferreira, J1
Parrino, A1
Shlobin, NA1
Rosenow, JM1
Singh, G1
Dash, HH1
Arora, D1
Costello, TG1
Cormack, JR1
Mather, LE1
LaFerlita, B1
Murphy, MA1
Harris, K1
Tobias, JD1
Jimenez, DF1
Bauman, GS1
Brett, CM1
Ciricillo, SF1
Larson, DA1
Sneed, P1
Staplers, LJ1
Edwards, M1
Wara, WM1
Schaffranietz, L1
Rüffert, H1
Trantakis, C1
Seifert, V1
Hartley, E1
Bissonnette, B1
St Louis, P1
Rybczynski, J1
McLeod, ME1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Scalp Block With Bupivacaine Versus Levobupivacaine on Haemodynamic Response to Head Pinning and Efficacy on Postoperative Analgesia[NCT02497040]Phase 490 participants (Actual)Interventional2008-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Mean Arterial Pressure

(NCT02497040)
Timeframe: 220+-70 minutes

InterventionmmHg (Mean)
Bupivacaine,Levobupivacaine110
Levobupivacaine105
Bupivacaine100

Reviews

1 review available for bupivacaine and Brain Neoplasms

ArticleYear
Nonopioid Postoperative Pain Management in Neurosurgery.
    Neurosurgery clinics of North America, 2022, Volume: 33, Issue:3

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Huma

2022

Trials

2 trials available for bupivacaine and Brain Neoplasms

ArticleYear
[Effect of local anesthetics on hemodynamic effects during Mayfield skull clamp fixation in neurosurgery using total intravenous anesthesia].
    Anaesthesiologie und Reanimation, 1999, Volume: 24, Issue:2

    Topics: Alfentanil; Anesthesia, Inhalation; Anesthesia, Local; Blood Pressure; Brain Neoplasms; Bupivacaine;

1999
Scalp infiltration with bupivacaine in paediatric brain surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2

    Topics: Anesthesia, Local; Brain Diseases; Brain Neoplasms; Bupivacaine; Child; Craniotomy; Dose-Response Re

1990

Other Studies

5 other studies available for bupivacaine and Brain Neoplasms

ArticleYear
Wide Awake Local Anesthesia No Tourniquet Technique in Hand Surgery: The Patient Experience.
    Hand (New York, N.Y.), 2023, Volume: 18, Issue:4

    Topics: Anesthesia, Local; Brain Neoplasms; Bupivacaine; Epinephrine; Hand; Humans; Lidocaine; Pain; Patient

2023
Inadvertent Neuraxial Anesthesia in a Patient With an Intracranial Space-occupying Lesion.
    Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:4

    Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Brain Neoplasms; Bu

2016
Plasma levobupivacaine concentrations following scalp block in patients undergoing awake craniotomy.
    British journal of anaesthesia, 2005, Volume: 94, Issue:6

    Topics: Adult; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Craniotomy; Epilepsy; Female; Humans; Levob

2005
Anaesthetic management during awake craniotomy in a 12-year-old boy.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:4

    Topics: Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Child

1997
Anesthesia for pediatric stereotactic radiosurgery.
    Anesthesiology, 1998, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Child

1998