Page last updated: 2024-10-24

bupivacaine and Bladder Cancer

bupivacaine has been researched along with Bladder Cancer in 20 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
" Four years previously, he underwent TURBT twice under spinal anesthesia with dibucaine, which caused severe leg pain during anesthesia."7.71[Spinal anesthesia with bupivacaine for a patient with a history of severe leg pain after intrathecal dibucaine]. ( Koizumi, Y; Masuda, N; Miyazaki, T; Saeki, H; Tamura, T; Yonei, A, 2002)
" Four years previously, he underwent TURBT twice under spinal anesthesia with dibucaine, which caused severe leg pain during anesthesia."3.71[Spinal anesthesia with bupivacaine for a patient with a history of severe leg pain after intrathecal dibucaine]. ( Koizumi, Y; Masuda, N; Miyazaki, T; Saeki, H; Tamura, T; Yonei, A, 2002)
"Ondansetron is a potent antiemetic and a competitive antagonist at serotonin receptors, which are also involved in modulation of pain."2.76Effect of intravenous ondansetron on sensory and motor block after spinal anaesthesia with hyperbaric bupivacaine. ( Bala, I; Chopra, K; Podder, S; Samra, T, 2011)
"Twenty patients with recurrent solitary bladder tumors were randomly allocated in two groups."2.73Levobupivacaine intravesical injection for superficial bladder tumor resection--possible, effective, and durable. Preliminary clinical data. ( Kapetanakis, T; Lampadariou, A; Mitropoulos, D; Salvari, A; Stravodimos, KG; Zervas, A, 2008)
"Fentanyl has been used as an adjunct to racemic bupivacaine in spinal anaesthesia."2.71Levobupivacaine and fentanyl for spinal anaesthesia: a randomized trial. ( Chan, CK; Cheung, AS; Lee, YY; Muchhal, K, 2005)
"Urinary bladder cancer is more common in geriatric population."1.91Ultrasound versus Nerve Stimulator Guided Obturator Nerve Block in Patients Undergoing Transurethral Resection of Bladder Tumor. ( Baral, BK; Dhakal, GR; Karki, AJ; Poudel, PR; Rajbhandari, M, 2023)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's1 (5.00)18.2507
2000's9 (45.00)29.6817
2010's4 (20.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Hao, J1
Zhang, W1
Huang, Z1
Baral, BK1
Poudel, PR1
Rajbhandari, M1
Karki, AJ1
Dhakal, GR1
Dagli, R1
Dadali, M1
Emir, L1
Bagbanci, S1
Ates, H1
Wallace, E1
Twomey, M1
Victory, R1
O'Reilly, M1
Lee, SJ1
Bai, SJ1
Lee, JS1
Kim, WO1
Shin, YS1
Lee, KY1
Cuvas, O2
Er, AE1
Ongen, E1
Basar, H2
Yeygel, A1
Turkyilmaz, E1
Sunay, MM1
Samra, T1
Bala, I1
Chopra, K1
Podder, S1
Miyazaki, T1
Tamura, T1
Koizumi, Y1
Saeki, H1
Masuda, N1
Yonei, A1
Lee, YY2
Muchhal, K2
Chan, CK2
Allard, R1
Hatzakorzian, R1
Deschamps, A1
Backman, SB1
Roberts, SA1
Galvez, I1
Cheung, AS1
Stravodimos, KG1
Mitropoulos, D1
Salvari, A1
Lampadariou, A1
Kapetanakis, T1
Zervas, A1
Rupieper, N1
Behrendt, H1
Marggraf, G1
Ringert, RH1
Homann, W1
Bovianska, N1
Lattermann, R1
Schricker, T1
Wachter, U1
Goertz, A1
Georgieff, M1
Siegel, Y1
Ezra, S1
Eting, A1
Danielli, L1
Lindner, A1
Glashan, RW2
Brown, PR2
Arthurs, GJ1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration: Randomized Controlled Trial[NCT01675895]Phase 440 participants (Actual)Interventional2009-07-31Completed
A Comparison of the Recovery Profiles of Bupivacaine or Bupivacaine Mixed With Lidocaine Spinal Anesthesia and Local Infiltration Anesthesia for Outpatient Herniorrhaphy[NCT01548794]Phase 493 participants (Actual)Interventional2012-03-31Completed
Comparison of Intratechal Low-Dose Levobupivacaine With Levobupivacaine-Fentanyl and Levobupivacaine-Sufentanil Combinations for Cesarean Section[NCT02430090]Phase 245 participants (Actual)Interventional2006-11-30Completed
Transesophageal Echocardiography (TEE) to Guide and Confirm Epidural Catheters in Pediatric Patients[NCT02415998]25 participants (Actual)Observational2012-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Adverse Events as a Measure of Safety and Tolerability

The frequency and the severity (ex) of the side effects including nausea and vomiting, hypotension, pruritus, and bradycardia were recorded. (NCT02430090)
Timeframe: Up to 4 months

Interventionparticipants (Number)
Levobupivacaine5
Levobupivacaine + Fentanyl10
Levobupivacaine + Sufentanil9

Number of Participants With Successful Epidural Catheter Placement

The success rate achieved using TEE guidance to thread an epidural catheter to within one targeted thoracic spinal level. Post-operative radiograph will be used to confirm catheter position. (NCT02415998)
Timeframe: within one day

InterventionParticipants (Count of Participants)
Successful placementUnsuccessful placement
TEE Guided Epidural Catheter Placement173

Trials

9 trials available for bupivacaine and Bladder Cancer

ArticleYear
Comparison of Classic and Inguinal Obturator Nerve Blocks Applied for Preventing Adductor Muscle Contractions in Bladder Tumor Surgeries: A Prospective Randomized Trial.
    Urology journal, 2019, 02-21, Volume: 16, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Groin; Humans; Male; Midd

2019
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
Spinal anesthesia for transurethral resection operations: bupivacaine versus levobupivacaine.
    Minerva anestesiologica, 2008, Volume: 74, Issue:12

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; Humans; Levobupivaca

2008
Spinal anesthesia for transurethral resection operations: levobupivacaine with or without fentanyl.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method;

2010
Effect of intravenous ondansetron on sensory and motor block after spinal anaesthesia with hyperbaric bupivacaine.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Bupivacaine; Double-Blind Method; Female; Human

2011
Levobupivacaine versus racemic bupivacaine in spinal anaesthesia for urological surgery.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:6

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Double-Blind Method; Fema

2003
Levobupivacaine and fentanyl for spinal anaesthesia: a randomized trial.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:12

    Topics: Adjuvants, Anesthesia; Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Combined; Anesthet

2005
Levobupivacaine intravesical injection for superficial bladder tumor resection--possible, effective, and durable. Preliminary clinical data.
    International urology and nephrology, 2008, Volume: 40, Issue:3

    Topics: Anesthetics, Local; Bupivacaine; Female; Humans; Levobupivacaine; Male; Middle Aged; Neoplasm Recurr

2008
Intraoperative epidural blockade prevents the increase in protein breakdown after abdominal surgery.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:9

    Topics: Abdomen; Aged; Amino Acids; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cystectomy; Femal

2001

Other Studies

11 other studies available for bupivacaine and Bladder Cancer

ArticleYear
Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Apoptosis; Bupivacaine; Cell Survival; Ferroptosis; Humans; Phosphatidylinositol 3-Kinase; Phosphati

2022
Ultrasound versus Nerve Stimulator Guided Obturator Nerve Block in Patients Undergoing Transurethral Resection of Bladder Tumor.
    Journal of Nepal Health Research Council, 2023, Jul-20, Volume: 20, Issue:4

    Topics: Aged; Bupivacaine; Humans; Nepal; Obturator Nerve; Prospective Studies; Transurethral Resection of B

2023
Intravesical baclofen, bupivacaine, and oxycodone for the relief of bladder spasm.
    Journal of palliative care, 2013,Spring, Volume: 29, Issue:1

    Topics: Administration, Intravesical; Aged; Analgesics, Opioid; Anesthetics, Local; Baclofen; Bupivacaine; D

2013
[Spinal anesthesia with bupivacaine for a patient with a history of severe leg pain after intrathecal dibucaine].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:11

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dibucaine; Humans; Leg

2002
Decreased heart rate and blood pressure in a recent cardiac transplant patient after spinal anesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure; Bupivacaine;

2004
Ultrasound assessment of caudal catheter position in infants.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:5

    Topics: Adenoma; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Ductus Arteriosus, Patent; Epidural Sp

2005
[Effect of spinal anesthesia on the function of the lower urinary tract].
    Intensivmedizinische Praxis, 1983, Volume: 6

    Topics: Aged; Anesthesia, Spinal; Bupivacaine; Humans; Male; Prostatic Hyperplasia; Urinary Bladder Neoplasm

1983
[Combined spinal and epidural analgesia in urology].
    Khirurgiia, 1995, Volume: 48, Issue:5

    Topics: Adult; Aged; Analgesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Carcinoma; Fe

1995
[Transurethral procedures with sacral anesthesia].
    Harefuah, 1989, Jun-01, Volume: 116, Issue:11

    Topics: Aged; Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Female; Humans; Male; Prostatectomy; Pr

1989
Initial experience with Helmstein's treatment by a hydrostatic pressure technique in carcinoma of the bladder.
    The British journal of surgery, 1974, Volume: 61, Issue:6

    Topics: Aged; Biopsy; Bupivacaine; Cystoscopy; Female; Follow-Up Studies; Humans; Hypotension, Controlled; M

1974
Epidural analgesia in the treatment of bladder carcinoma. A technique using two catheters.
    Anaesthesia, 1974, Volume: 29, Issue:4

    Topics: Aged; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Diazepam; Female; Humans;

1974