bupivacaine has been researched along with Appendicitis in 13 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Appendicitis: Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No differences were noted in postoperative pain, the total number of analgesic doses per day, the quantity of narcotic medication administered, and the length of hospital stay." | 2.68 | Preemptive analgesia in patients undergoing appendectomy. ( Alcantara, A; Hiyama, D; Ko, CY; Thompson, JE, 1997) |
| "Assessment of postoperative pain using a numerical scoring system was made by the child, the recovery sister and the ward sister, and by measurement of the time between the end of the operation and the need for narcotic injection." | 2.67 | Controlled trial of wound infiltration with bupivacaine for postoperative pain relief after appendicectomy in children. ( Wright, JE, 1993) |
| "The patient reported mild postoperative pain scores, was able to ambulate comfortably on the day of surgery, and had early return of bowel function." | 1.42 | Multimodal analgesia in abdominal sepsis: a case report of liposome bupivacaine in ultrasound-guided rectus sheath blocks after unexpected open hemi-colectomy. ( Patzkowski, MS; Stevens, G, 2015) |
| "Morphine requirements were markedly less for CLAWI." | 1.42 | Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control. ( Albetyn, H; Cox, SG; Machoki, MS; Millar, AJ; Numanoglu, A; Thomas, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Waddimba, AC | 1 |
| Newman, P | 1 |
| Shelley, JK | 1 |
| McShan, EE | 1 |
| Cheung, ZO | 1 |
| Gibson, JN | 1 |
| Bennett, MM | 1 |
| Petrey, LB | 1 |
| Hernandez, MC | 1 |
| Finnesgard, EJ | 1 |
| Aho, JM | 1 |
| Zielinski, MD | 1 |
| Schiller, HJ | 1 |
| Hamill, JK | 2 |
| Liley, A | 2 |
| Hill, AG | 2 |
| Patzkowski, MS | 1 |
| Stevens, G | 1 |
| Machoki, MS | 1 |
| Millar, AJ | 1 |
| Albetyn, H | 1 |
| Cox, SG | 1 |
| Thomas, J | 1 |
| Numanoglu, A | 1 |
| Durai, R | 1 |
| Ng, PC | 1 |
| Delfosse, F | 1 |
| Pronnier, P | 1 |
| Levent, T | 1 |
| Coget, ML | 1 |
| Blanckaert, K | 1 |
| Wasiluk, I | 1 |
| Attali, A | 1 |
| Manimekalai, N | 1 |
| Panni, MK | 1 |
| Lohsiriwat, V | 1 |
| Lert-akyamanee, N | 1 |
| Rushatamukayanunt, W | 1 |
| Brimacombe, J | 1 |
| Newell, S | 1 |
| Wright, JE | 1 |
| Ko, CY | 1 |
| Thompson, JE | 1 |
| Alcantara, A | 1 |
| Hiyama, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ROPIVACAINE WITH CLONIDINE FOR PEDIATRIC RECTUS SHEATH BLOCKS- THE MAGIC COMBINATION? - A Double Blinded Prospective Study[NCT02439281] | 50 participants (Actual) | Interventional | 2015-05-31 | Terminated (stopped due to The patients were discharged on the day of the surgery.) | |||
| Laparoscopically Guided Rectus Sheath Block in Pediatric Appendicitis - a Randomized Control Trial[NCT04717193] | Phase 2 | 100 participants (Anticipated) | Interventional | 2021-05-28 | Recruiting | ||
| Liposomal Bupivacaine/Bupivacaine A Single-Dose Bilateral Rectus Sheath Blocks Vs. Ropivacaine in Bilateral RS Blocks And Catheters, Comparing Pain Scores And Opioid Use Following Open Abdominal Vascular Surgery[NCT05972018] | Phase 4 | 50 participants (Anticipated) | Interventional | 2023-10-18 | Recruiting | ||
| Evaluation of Aerosolized Bupivacaine Versus Pre-incision Lidocaine Versus Instilled Liquid Bupivacaine Versus Post-operative Bupivacaine Injection for Optimization of Post-operative Pain Control in Laparoscopic Bariatric Surgical Patients[NCT00508976] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| The Evaluation of Pre-incisional and Post-closure Local Anesthetic vs. Normal Saline on Postoperative Pain in Pediatric Appendectomies[NCT02483689] | 100 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Numeric Rating Pain Scores ( 0-10), will be obtained every 2 hours after PACU discharge up to 18 hours or until hospital discharge, whichever occurs first. The pain score of 0, means no pain, is a good outcome , and a pain score of 10 is excruciating pain, a very bad outcome. The average of these scores will be evaluated.The pain scores will not longer be documented after the numbness went away. (NCT02439281)
Timeframe: Logistic regression of the 4 th pain score assessment
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine Group | 2 |
| Ropivacaine/ Clonidine Group | 1.5 |
The investigators hypothesize that patient postoperative anxiety scores are lower in the Ropivacaine/Clonidine group and postoperative anxiety scores decrease more in Ropivacaine /Clonidine Group, than in Ropivacaine Group. (NCT02439281)
Timeframe: 6 hours after block placement
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine Group | 30 |
| Ropivacaine/ Clonidine Group | 29 |
The investigators expect no difference in incidence of complications (e.g. oversedation, hypotension, bradycardia episodes, etc.). (NCT02439281)
Timeframe: until study completion
| Intervention | Participants (Count of Participants) |
|---|---|
| Ropivacaine/ Clonidine Group | 1 |
| Ropivacaine Group | 1 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in longer duration of analgesia and decreased pain scores compared to ropivacaine alone. (NCT02439281)
Timeframe: indicated by the first request for pain medication at umbilicus site
| Intervention | minutes (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 230 |
| Ropivacaine Group | 240 |
The investigators hypothesize that rectus sheath injections with ropivacaine and clonidine result in longer duration of sensory block (paresthesia) compared to ropivacaine alone. (NCT02439281)
Timeframe: Indicated by return of normal sensation (expected average of 12 hours after block placement).
| Intervention | minutes (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 823.5 |
| Ropivacaine Group | 540 |
Total intravenous morphine equivalents mg/kg (NCT02439281)
Timeframe: 18 hours after surgery
| Intervention | mg/kg (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 0.20 |
| Ropivacaine Group | 0.22 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in better satisfaction with pain control. (NCT02439281)
Timeframe: Prior to hospital discharge (up to 24 hours after surgery)
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 9 |
| Ropivacaine Group | 9 |
5 trials available for bupivacaine and Appendicitis
| Article | Year |
|---|---|
Rectus sheath block for laparoscopic appendicectomy: a randomized clinical trial.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Child; | 2015 |
Rectus sheath block for laparoscopic appendicectomy: a randomized clinical trial.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Child; | 2015 |
Rectus sheath block for laparoscopic appendicectomy: a randomized clinical trial.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Child; | 2015 |
Rectus sheath block for laparoscopic appendicectomy: a randomized clinical trial.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Child; | 2015 |
Intraperitoneal Local Anesthetic for Laparoscopic Appendectomy in Children: A Randomized Controlled Trial.
Topics: Acute Disease; Adolescent; Anesthesia, Local; Anesthetics, Local; Appendectomy; Appendicitis; Bupiva | 2017 |
Efficacy of pre-incisional bupivacaine infiltration on postoperative pain relief after appendectomy: prospective double-blind randomized trial.
Topics: Adolescent; Adult; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Double-Blind Method; | 2004 |
Controlled trial of wound infiltration with bupivacaine for postoperative pain relief after appendicectomy in children.
Topics: Adolescent; Appendectomy; Appendicitis; Bupivacaine; Child; Double-Blind Method; Female; Humans; Mal | 1993 |
Preemptive analgesia in patients undergoing appendectomy.
Topics: Acute Disease; Adolescent; Adult; Analgesia; Anesthetics, Local; Appendicitis; Bupivacaine; Double-B | 1997 |
8 other studies available for bupivacaine and Appendicitis
| Article | Year |
|---|---|
Pain management after laparoscopic appendectomy: Comparative effectiveness of innovative pre-emptive analgesia using liposomal bupivacaine.
Topics: Adult; Analgesia; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; H | 2022 |
Reduced Opioid Prescription Practices and Duration of Stay after TAP Block for Laparoscopic Appendectomy.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacaine; Drug Toleran | 2020 |
Multimodal analgesia in abdominal sepsis: a case report of liposome bupivacaine in ultrasound-guided rectus sheath blocks after unexpected open hemi-colectomy.
Topics: Abdominal Muscles; Administration, Intravenous; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesi | 2015 |
Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2015 |
Mittelschmerz mimicking appendicitis.
Topics: Adult; Analgesics; Appendicitis; Bupivacaine; Diagnosis, Differential; Female; Humans; Menstruation | 2009 |
[Infections complicating femoral nerve catheter for postoperative analgesia: about two cases].
Topics: Anesthetics, Local; Appendectomy; Appendicitis; Arthroplasty, Replacement, Knee; Bupivacaine; Cathet | 2011 |
Novel use of a continuous intrathecal catheter for appendectomy following cesarean section.
Topics: Acute Disease; Adult; Anesthesia, Spinal; Anesthetics, Local; Appendectomy; Appendicitis; Bupivacain | 2012 |
Successful anaesthetic management of a patient with thyrotoxic hypokalaemic periodic paralysis for coincidental appendicitis.
Topics: Adult; Anesthesia, Spinal; Appendicitis; Bupivacaine; Carbimazole; Humans; Hypokalemia; Male; Paraly | 1995 |