Page last updated: 2024-10-23

bupivacaine and Anxiety

bupivacaine has been researched along with Anxiety in 14 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block."9.08Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998)
"To investigate the efficacy of bupivacaine-soaked spongostan in cesarean section wound for postoperative anxiety level, satisfaction and early postpartum depression rate."5.19Effect of bupivacaine-soaked spongostan in cesarean section wound on postoperative maternal health. ( Kafali, H; Kaygusuz, I; Simavli, S, 2014)
"Effective labour analgesia lasting up to 120 minutes was observed in the fentanyl-bupivacaine group but with high incidence of breakthrough pain."5.17A COMPARATIVE STUDY ON THE EFFICACY OF TWO REGIMENS OF SINGLE- SHOT SPINAL BLOCK FOR PAIN RELIEF IN WOMEN PRESENTING IN ESTABLISHED LABOUR. ( Chokwe, TM; Ogutu, O; Olang, PO; Tshibuyl, PN, 2013)
"To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block."5.08Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998)
" Hypotension was treated by standardized protocol (fluid bolus and ephedrine or phenylephrine depending on maternal heart rate)."3.78Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery. ( Abu-Lil, M; Eidelman, LA; Elliston, J; Fadon, C; Ginosar, Y; Goshen-Gottstein, Y; Orbach-Zinger, S; Raz, A, 2012)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's2 (14.29)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Bahar-Ozdemir, Y1
Sencan, S1
Ercalik, T1
Kokar, S1
Gunduz, OH1
Rezniczek, GA1
Hecken, JM1
Rehman, S1
Dogan, A1
Tempfer, CB1
Hilal, Z1
Ueshima, H1
Shimazaki, A1
Otake, H1
Tomaszek, L1
Cepuch, G1
Fenikowski, D1
Simavli, S1
Kaygusuz, I1
Kafali, H1
Tshibuyl, PN1
Olang, PO1
Ogutu, O1
Chokwe, TM1
Sahin, T1
Gulec, E1
Sarac Ahrazoglu, M1
Tetiker, S1
Orbach-Zinger, S1
Ginosar, Y1
Elliston, J1
Fadon, C1
Abu-Lil, M1
Raz, A1
Goshen-Gottstein, Y1
Eidelman, LA1
Marucci, M1
Diele, C1
Bruno, F1
Fiore, T1
Iohom, G1
Abdalla, H1
O'Brien, J1
Szarvas, S1
Larney, V1
Buckley, E1
Butler, M1
Shorten, GD1
Davies, SJ1
Paech, MJ1
Welch, H1
Evans, SF1
Pavy, TJ1
Boezaart, AP1
Berry, RA1
Laubscher, JJ1
Nell, ML1
Aono, J1
Mamiya, K1
Manabe, M1
Rundshagen, I1
Schnabel, K1
Standl, T1
Schulte am Esch, J1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial[NCT05132114]216 participants (Anticipated)Interventional2022-01-17Recruiting
Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.[NCT03494686]229 participants (Actual)Interventional2018-04-03Completed
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia in Children and Adolescents After Thoracic Surgeries: a Randomized Double Blind Study[NCT03488459]112 participants (Actual)Interventional2012-03-01Completed
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension in Preoperatively Anxious Parturients Undergoing Urgent Category-1 Cesarean Section: A Historical Cohort Study[NCT02732197]102 participants (Actual)Observational2014-08-31Completed
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non-elective Caesarean Section: A Prospective Observational Study[NCT04692870]337 participants (Actual)Observational2021-01-06Completed
The Effect of Preoperative Anxiety on Phenylephrine Dosage During Cesarean Delivery Under Spinal Anesthesia, A Prospective Observational Study.[NCT03696732]100 participants (Anticipated)Observational2018-10-20Recruiting
A Randomized Prospective Placebo-Controlled Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients[NCT01837966]93 participants (Actual)Interventional2013-01-31Completed
Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674]200 participants (Actual)Interventional2014-11-30Completed
Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954]54 participants (Actual)Interventional2018-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anxiety Reduction

We hoped to show that lavender aroma therapy reduces preoperative anxiety in patients undergoing breast. The Trait subscale (STAI-TRAID) of the Spielberger State-Trait Anxiety Inventory was administered before and after 10 minutes of aromatherapy treatment pre-surgery. The TRAIT subscale contains 20 questions scored on a Likert scale from 1-4; item scores are summed for a total score ranging from 20 to 80, with higher scores indicating higher anxiety. Change in anxiety was calculated as the score pre-aromatherapy minus the score post-aromatherapy. Higher positive change scores indicate greater reductions in anxiety. (NCT01837966)
Timeframe: 20 minutes before surgery (pre aromatherapy) and 10 minutes before surgery (post aromatherapy)

Interventionunits on a scale (Mean)
Lavender Oil0.89
Placebo.74

Trials

9 trials available for bupivacaine and Anxiety

ArticleYear
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Influence of preoperative information support on anxiety, pain and satisfaction with postoperative analgesia in children and adolescents after thoracic surgery: A randomized double blind study.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2019, Volume: 163, Issue:2

    Topics: Adolescent; Analgesics; Anxiety; Bupivacaine; Child; Double-Blind Method; Female; Fentanyl; Humans;

2019
Effect of bupivacaine-soaked spongostan in cesarean section wound on postoperative maternal health.
    Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:2

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Anxiety; Bupivacaine

2014
A COMPARATIVE STUDY ON THE EFFICACY OF TWO REGIMENS OF SINGLE- SHOT SPINAL BLOCK FOR PAIN RELIEF IN WOMEN PRESENTING IN ESTABLISHED LABOUR.
    East African medical journal, 2013, Volume: 90, Issue:1

    Topics: Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Combined; Anesthetics,

2013
Subarachnoid anaesthesia in caesarean delivery: effects on alertness.
    Minerva anestesiologica, 2003, Volume: 69, Issue:11

    Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Anxiety;

2003
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Di

2006
Maternal experience during epidural or combined spinal-epidural anesthesia for cesarean section: a prospective, randomized trial.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesth

1997
Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:3

    Topics: Aged; Alprazolam; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Bromazepam; B

1998
Patients' vs nurses' assessments of postoperative pain and anxiety during patient- or nurse-controlled analgesia.
    British journal of anaesthesia, 1999, Volume: 82, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesia, Patient-Controlled; Analgesics, Op

1999

Other Studies

5 other studies available for bupivacaine and Anxiety

ArticleYear
The Effect of Pre-Treatment Depression, Anxiety and Somatization Levels on Transforaminal Epidural Steroid Injection: A Prospective Observational Study.
    Pain physician, 2020, Volume: 23, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anxiety; Bupivacaine; Depression; Female;

2020
RETRACTED: Cervical plexus block for perioperative analgesia during otoplasty.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Analgesia; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Loca

2017
Association between preoperative maternal anxiety and neonatal outcomes: a prospective observational study.
    Journal of clinical anesthesia, 2016, Volume: 33

    Topics: Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Anxiety; Apgar S

2016
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Influence of preoperative anxiety on hypotension after spinal anaesthesia in women undergoing Caesarean delivery.
    British journal of anaesthesia, 2012, Volume: 109, Issue:6

    Topics: Adult; Amylases; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Int

2012
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999