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bupivacaine and Anoxemia

bupivacaine has been researched along with Anoxemia in 30 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"Interpleural blockade with bupivacaine has been used in operations and for the treatment of pain with promising results."9.08Does interpleural bupivacaine blockade reduce arterial hypoxemia and pain in endoscopic retrograde cholangiopancreatography? A prospective randomized trial. ( Andersen, N; Axelsson, CK; Romer, UD; Wamberg, PA, 1998)
"This study examined whether combining lipid emulsion and advanced cardiac life support (ACLS) improves survival in an unanesthetized swine model of bupivacaine- and hypoxia-induced cardiovascular collapse."7.77Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine. ( Auld, VH; Bushey, BA; Vacchiano, CA; Volk, JE, 2011)
"In this animal study pretreatment with bupivacaine attenuated the progression of myocardial acidosis during ventricular fibrillation."7.72The effect of bupivacaine on myocardial tissue hypoxia and acidosis during ventricular fibrillation. ( Feinstein, D; Hoffman, W; Paisanthasan, C; Weinberg, G, 2004)
"Chronic hypoxia impairs cardiac energy metabolism in left ventricles and enhances the depressant effects of bupivacaine on mitochondrial functions."7.71Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia. ( Forestier, F; Malgat, M; Marthan, R; Mazat, JP; Nouette-Gaulain, K; Sztark, F, 2002)
"Toxic systemic reactions to bupivacaine usually involve a number of factors, including hypoxia and acidosis."7.68Severe hypoxia enhances central nervous system and cardiovascular toxicity of bupivacaine in lightly anesthetized pigs. ( Badgwell, JM; Bessire, A; Dryden, CF; Heavner, JE; Huemer, G; Sanghani, V, 1992)
" The aim of this study was to compare the effects of lidocaine and bupivacaine on the intrinsic pacemaker activity of in vitro sinoatrial nodal cells of the adult and neonatal guinea pig in the presence and absence of hypoxia and acidosis."7.67Comparison of lidocaine and bupivacaine depression of sinoatrial nodal activity during hypoxia and acidosis in adult and neonatal guinea pigs. ( Bosnjak, ZJ; Kampine, JP; Stowe, DF, 1986)
" In this double-blinded pharmacodynamic study with a two-parallel-group design, we investigated, during a 24-h period, the effects of intrathecal sameridine and bupivacaine on ventilation at rest and at ventilatory challenges during hypercarbia and hypoxia."5.10Hypercarbic and hypoxic ventilatory responses after intrathecal administration of bupivacaine and sameridine. ( Arlander, E; Eriksson, LI; Lindahl, SG; Modalen, AO; Westman, L, 2003)
"Interpleural blockade with bupivacaine has been used in operations and for the treatment of pain with promising results."5.08Does interpleural bupivacaine blockade reduce arterial hypoxemia and pain in endoscopic retrograde cholangiopancreatography? A prospective randomized trial. ( Andersen, N; Axelsson, CK; Romer, UD; Wamberg, PA, 1998)
" In spinal anaesthesia hypotension of clinical importance was observed coincidentally with the use of methylmethacrylate, while the levels of plasma cortisol remained unchanged."5.06The effect of anaesthesia on changes in blood pressure and plasma cortisol levels induced by cementation with methylmethacrylate. ( Lehtinen, AM; Svartling, N; Tarkkanen, L, 1986)
" Methemoglobinemia was suspected and treated with ascorbine acid and methylene blue."3.77[Toxic methemoglobinemia]. ( Bender, P; Neuhaus, H, 2011)
"This study examined whether combining lipid emulsion and advanced cardiac life support (ACLS) improves survival in an unanesthetized swine model of bupivacaine- and hypoxia-induced cardiovascular collapse."3.77Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine. ( Auld, VH; Bushey, BA; Vacchiano, CA; Volk, JE, 2011)
"In this animal study pretreatment with bupivacaine attenuated the progression of myocardial acidosis during ventricular fibrillation."3.72The effect of bupivacaine on myocardial tissue hypoxia and acidosis during ventricular fibrillation. ( Feinstein, D; Hoffman, W; Paisanthasan, C; Weinberg, G, 2004)
"Chronic hypoxia impairs cardiac energy metabolism in left ventricles and enhances the depressant effects of bupivacaine on mitochondrial functions."3.71Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia. ( Forestier, F; Malgat, M; Marthan, R; Mazat, JP; Nouette-Gaulain, K; Sztark, F, 2002)
"Toxic systemic reactions to bupivacaine usually involve a number of factors, including hypoxia and acidosis."3.68Severe hypoxia enhances central nervous system and cardiovascular toxicity of bupivacaine in lightly anesthetized pigs. ( Badgwell, JM; Bessire, A; Dryden, CF; Heavner, JE; Huemer, G; Sanghani, V, 1992)
" The aim of this study was to compare the effects of lidocaine and bupivacaine on the intrinsic pacemaker activity of in vitro sinoatrial nodal cells of the adult and neonatal guinea pig in the presence and absence of hypoxia and acidosis."3.67Comparison of lidocaine and bupivacaine depression of sinoatrial nodal activity during hypoxia and acidosis in adult and neonatal guinea pigs. ( Bosnjak, ZJ; Kampine, JP; Stowe, DF, 1986)
"The overall incidence of episodic hypoxemia was 56% (28 of 50 patients) on the second postoperative night and 89% (41 of 46 patients) on the third postoperative night."2.71The effect of thoracic epidural analgesia on the occurrence of late postoperative hypoxemia in patients undergoing elective coronary bypass surgery: a randomized controlled trial. ( Aldershvile, J; Hviid, LB; Lundstrøm, LH; Nygård, E; Pedersen, FM; Ravn, J; Rosenberg, J, 2005)
"The two groups were compared for postoperative pain scores, satisfaction, sedation and oxygen saturation."2.69Postoperative hypoxaemia: continuous extradural infusion of bupivacaine and morphine vs patient-controlled analgesia with intravenous morphine. ( Bourgain, JL; Farhat, F; Jayr, C; Lasser, P; Motamed, C; Spencer, A, 1998)
"We have examined postoperative pain in patients allocated randomly to receive extradural bolus diamorphine 3."2.67Hypoxaemia and pain relief after lower abdominal surgery: comparison of extradural and patient-controlled analgesia. ( Hunter, D; Jackson, IJ; Madej, TH; Wheatley, RG, 1992)
"Pruritus was observed in 29% of patients and was more common in diplegia than quadriplegia (48% vs 12."1.30Epidural analgesia in children with cerebral palsy. ( Brenn, BR; Brislin, RP; Rose, JB, 1998)
"During hypoxemia vasopressin concentrations increased 35-fold to 64 pg/ml +/- 38 (P less than 0."1.28Sympathetic blockade by epidural anesthesia attenuates the cardiovascular response to severe hypoxemia. ( Arndt, JO; Kutkuhn, B; Medert, HA; Peters, J; Schlaghecke, R; Schüttler, J, 1990)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's10 (33.33)18.2507
2000's4 (13.33)29.6817
2010's6 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakanishi, M1
Okura, N1
Kashii, T1
Matsushita, M1
Mori, M1
Yoshida, M1
Tsujimura, S1
Heinonen, JA1
Skrifvars, MB1
Haasio, J1
Backman, JT1
Rosenberg, PH1
Litonius, E1
Elhakim, M1
Abdelhamid, D1
Abdelfattach, H1
Magdy, H1
Elsayed, A1
Elshafei, M1
Bender, P1
Neuhaus, H1
Bushey, BA1
Auld, VH1
Volk, JE1
Vacchiano, CA1
Zider, B1
Nouette-Gaulain, K1
Forestier, F1
Malgat, M1
Marthan, R1
Mazat, JP1
Sztark, F1
Modalen, AO1
Westman, L1
Arlander, E1
Eriksson, LI1
Lindahl, SG1
Weinberg, G1
Paisanthasan, C1
Feinstein, D1
Hoffman, W1
Lundstrøm, LH1
Nygård, E1
Hviid, LB1
Pedersen, FM1
Ravn, J1
Aldershvile, J1
Rosenberg, J1
Sage, DJ1
Feldman, HS1
Arthur, GR1
Datta, S1
Ferretti, AM1
Norway, SB1
Covino, BG2
Moore, DC2
Crawford, RD2
Scurlock, JE1
Thompson, GE1
Griffin, RP1
Reynolds, F1
Moritz, JD1
Layer, G1
Träber, F1
Kuhl, C1
Schüller, H1
Reiser, M1
Sjöberg, F1
Bengtsson, M1
Axelsson, CK1
Wamberg, PA1
Andersen, N1
Romer, UD1
Motamed, C1
Spencer, A1
Farhat, F1
Bourgain, JL1
Lasser, P1
Jayr, C1
Brenn, BR1
Brislin, RP1
Rose, JB1
Spence, AA1
Logan, DA1
Madej, TH1
Wheatley, RG1
Jackson, IJ1
Hunter, D1
Heavner, JE1
Dryden, CF1
Sanghani, V1
Huemer, G1
Bessire, A1
Badgwell, JM1
Entwistle, MD1
Roe, PG1
Sapsford, DJ1
Berrisford, RG1
Jones, JG1
Peters, J1
Kutkuhn, B1
Medert, HA1
Schlaghecke, R1
Schüttler, J1
Arndt, JO1
Kato, H1
Menon, AS1
Chen, FJ1
Slutsky, AS1
Svartling, N1
Lehtinen, AM1
Tarkkanen, L1
Bosnjak, ZJ1
Stowe, DF1
Kampine, JP1
Rosen, MA1
Thigpen, JW1
Shnider, SM1
Foutz, SE1
Levinson, G1
Koike, M1
Thiery, M1
De Clercq, A1
Rolly, G1
Derom, R1
Vroman, S1
Diesbecq, W1

Reviews

1 review available for bupivacaine and Anoxemia

ArticleYear
Recent advances in local anaesthesia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2

    Topics: Acidosis; Anesthesia, Local; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Cardiov

1986

Trials

9 trials available for bupivacaine and Anoxemia

ArticleYear
Effect of epidural dexmedetomidine on intraoperative awareness and post-operative pain after one-lung ventilation.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthesia, Genera

2010
Hypercarbic and hypoxic ventilatory responses after intrathecal administration of bupivacaine and sameridine.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: Adult; Algorithms; Anesthetics, Local; Bupivacaine; Carbon Dioxide; Conscious Sedation; Double-Blind

2003
The effect of thoracic epidural analgesia on the occurrence of late postoperative hypoxemia in patients undergoing elective coronary bypass surgery: a randomized controlled trial.
    Chest, 2005, Volume: 128, Issue:3

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Coronary Artery Bypa

2005
Maternal hypoxaemia during labour and delivery: the influence of analgesia and effect on neonatal outcome.
    Anaesthesia, 1995, Volume: 50, Issue:2

    Topics: Adult; Analgesia, Obstetrical; Analgesics; Anesthetics; Bupivacaine; Cardiotocography; Drug Combinat

1995
Does interpleural bupivacaine blockade reduce arterial hypoxemia and pain in endoscopic retrograde cholangiopancreatography? A prospective randomized trial.
    Endoscopy, 1998, Volume: 30, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Bupivacaine; Cholangiopancreatography, Endoscopic Retrograde; Female

1998
Postoperative hypoxaemia: continuous extradural infusion of bupivacaine and morphine vs patient-controlled analgesia with intravenous morphine.
    British journal of anaesthesia, 1998, Volume: 80, Issue:6

    Topics: Abdominal Neoplasms; Adolescent; Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; An

1998
Hypoxaemia and pain relief after lower abdominal surgery: comparison of extradural and patient-controlled analgesia.
    British journal of anaesthesia, 1992, Volume: 69, Issue:6

    Topics: Abdomen; Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Female; Heroi

1992
Patterns of oxygenation after thoracotomy.
    British journal of anaesthesia, 1991, Volume: 67, Issue:6

    Topics: Adult; Aged; Bupivacaine; Female; Humans; Hypoxia; Male; Middle Aged; Opium; Oxygen; Oxygen Inhalati

1991
The effect of anaesthesia on changes in blood pressure and plasma cortisol levels induced by cementation with methylmethacrylate.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:3

    Topics: Aged; Anesthesia, Endotracheal; Anesthesia, Spinal; Bupivacaine; Female; Femoral Neck Fractures; Hip

1986

Other Studies

20 other studies available for bupivacaine and Anoxemia

ArticleYear
[Case of lymphangioleiomyomatosis (LAM) discovered during cesarean section under spinal anesthesia].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:2

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Cesarean Section; Female; Humans; H

2014
Intravenous lipid emulsion for levobupivacaine intoxication in acidotic and hypoxaemic pigs.
    Anaesthesia and intensive care, 2016, Volume: 44, Issue:2

    Topics: Acidosis; Anesthetics, Local; Animals; Bupivacaine; Carbon Dioxide; Electrocardiography; Fat Emulsio

2016
[Toxic methemoglobinemia].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:15

    Topics: Ambulatory Surgical Procedures; Anesthetics, Local; Bupivacaine; Critical Care; Diagnosis, Different

2011
Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine.
    AANA journal, 2011, Volume: 79, Issue:2

    Topics: Advanced Cardiac Life Support; Anesthetics, Local; Animals; Bupivacaine; Combined Modality Therapy;

2011
Are pigs the right model for lipid resuscitation?
    AANA journal, 2011, Volume: 79, Issue:6

    Topics: Advanced Cardiac Life Support; Animals; Bupivacaine; Fat Emulsions, Intravenous; Hypoxia; Male; Shoc

2011
Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Anesthetics, Local; Animals; Bupivacaine; Energy Metabolism; Hypoxia; Male; Mitochondria, Heart; Oxi

2002
The effect of bupivacaine on myocardial tissue hypoxia and acidosis during ventricular fibrillation.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Acidosis; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Bupivacaine; Carbon Dioxi

2004
Influence of lidocaine and bupivacaine on isolated guinea pig atria in the presence of acidosis and hypoxia.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:1

    Topics: Acidosis; Animals; Bupivacaine; Guinea Pigs; Heart Atria; Heart Rate; Hypoxia; In Vitro Techniques;

1984
Severe hypoxia and acidosis following local anesthetic-induced convulsions.
    Anesthesiology, 1980, Volume: 53, Issue:3

    Topics: Acidosis; Adolescent; Adult; Anesthesia, Local; Blood; Bupivacaine; Carbon Dioxide; Female; Humans;

1980
Long-acting local anesthetic drugs and convulsions with hypoxia and acidosis.
    Anesthesiology, 1982, Volume: 56, Issue:3

    Topics: Acidosis; Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Hypoxia; Middle Aged; Seizures

1982
[Metabolic studies of the calf musculature with 31P-MR spectroscopy in arterial obstructive disease before and after lumbar sympatholysis].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1993, Volume: 159, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arterial Occlusive Diseases; Bupivacaine; Energy

1993
Is epidural morphine and bupivacaine safe on surgical wards?
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:5

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Gene

1998
Epidural analgesia in children with cerebral palsy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cerebral Palsy; Child; Con

1998
Respiratory effects of extradural nerve block in the postoperative period.
    British journal of anaesthesia, 1975, Volume: 47 suppl

    Topics: Anesthesia, Epidural; Bupivacaine; Epinephrine; Functional Residual Capacity; Humans; Hypoxia; Morph

1975
Severe hypoxia enhances central nervous system and cardiovascular toxicity of bupivacaine in lightly anesthetized pigs.
    Anesthesiology, 1992, Volume: 77, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Electroencephalo

1992
Sympathetic blockade by epidural anesthesia attenuates the cardiovascular response to severe hypoxemia.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Anesthesia, Epidural; Animals; Bupivacaine; Dogs; Epinephrine; Hemodynamics; Hypoxia; Norepinephrine

1990
Contribution of pulmonary receptors to the heart rate response to acute hypoxemia in rabbits.
    Circulation, 1988, Volume: 78, Issue:5 Pt 1

    Topics: Acute Disease; Afferent Pathways; Animals; Bupivacaine; Cough; Female; Heart Rate; Hypoxia; Lung; Ma

1988
Comparison of lidocaine and bupivacaine depression of sinoatrial nodal activity during hypoxia and acidosis in adult and neonatal guinea pigs.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:9

    Topics: Acidosis; Action Potentials; Age Factors; Animals; Animals, Newborn; Bupivacaine; Depression, Chemic

1986
Bupivacaine-induced cardiotoxicity in hypoxic and acidotic sheep.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:11

    Topics: Acidosis, Respiratory; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Dose-Response Rel

1985
The fetal influence of continuous lumbar epidural analgesia in labor.
    Acta anaesthesiologica Belgica, 1974, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Female; Fetal Disease

1974