Page last updated: 2024-10-24

bupivacaine and Ankle Fractures

bupivacaine has been researched along with Ankle Fractures in 3 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Ankle Fractures: Fractures of any of the bones of the ANKLE.

Research Excerpts

ExcerptRelevanceReference
"To determine the efficacy of liposomal bupivacaine compared to placebo for postoperative pain control in patients undergoing operative fixation of ankle fractures."9.24The Use of Liposomal Bupivacaine Administered With Standard Bupivacaine in Ankle Fractures Requiring Open Reduction Internal Fixation: A Single-Blinded Randomized Controlled Trial. ( Davidovitch, R; Driesman, A; Egol, K; Goch, A; Konda, S; Pean, C, 2017)
"To determine the efficacy of liposomal bupivacaine compared to placebo for postoperative pain control in patients undergoing operative fixation of ankle fractures."5.24The Use of Liposomal Bupivacaine Administered With Standard Bupivacaine in Ankle Fractures Requiring Open Reduction Internal Fixation: A Single-Blinded Randomized Controlled Trial. ( Davidovitch, R; Driesman, A; Egol, K; Goch, A; Konda, S; Pean, C, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davidovitch, R1
Goch, A1
Driesman, A1
Konda, S1
Pean, C1
Egol, K1
Sort, R1
Brorson, S1
Gögenur, I1
Møller, AM1
Herbst, SA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Continuous Nerve Catheters on Pain Control and Post-Operative Opioid Use in Receiving Popliteal Nerve Blocks for Below the Knee Amputation[NCT05140499]Phase 430 participants (Anticipated)Interventional2022-08-15Recruiting
Does the Use of Liposomal Bupivacaine Decrease Narcotic Requirements in Geriatric Hip Fractures? A Randomized, Double Blinded Control Trial[NCT03289858]Phase 455 participants (Actual)Interventional2017-09-01Completed
A Prospective, Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia, and Traditional Care for Pain Control of Operatively Treated Ankle Fractures[NCT03696199]Phase 470 participants (Anticipated)Interventional2020-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Opiate Requirements

Morphine meq given (NCT03289858)
Timeframe: 72 hours

InterventionMorphine mEq (Mean)
Exparel (Liposomal Bupivacaine)52.5
Saline Control65.39

Reviews

1 review available for bupivacaine and Ankle Fractures

ArticleYear
Local infiltration of liposome bupivacaine in foot and ankle surgery: case-based reviews.
    American journal of orthopedics (Belle Mead, N.J.), 2014, Volume: 43, Issue:10 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Ankle Fractures; Ankle Joint; Arthroplasty, Replacement, Ankl

2014
Local infiltration of liposome bupivacaine in foot and ankle surgery: case-based reviews.
    American journal of orthopedics (Belle Mead, N.J.), 2014, Volume: 43, Issue:10 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Ankle Fractures; Ankle Joint; Arthroplasty, Replacement, Ankl

2014
Local infiltration of liposome bupivacaine in foot and ankle surgery: case-based reviews.
    American journal of orthopedics (Belle Mead, N.J.), 2014, Volume: 43, Issue:10 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Ankle Fractures; Ankle Joint; Arthroplasty, Replacement, Ankl

2014
Local infiltration of liposome bupivacaine in foot and ankle surgery: case-based reviews.
    American journal of orthopedics (Belle Mead, N.J.), 2014, Volume: 43, Issue:10 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Ankle Fractures; Ankle Joint; Arthroplasty, Replacement, Ankl

2014

Trials

2 trials available for bupivacaine and Ankle Fractures

ArticleYear
The Use of Liposomal Bupivacaine Administered With Standard Bupivacaine in Ankle Fractures Requiring Open Reduction Internal Fixation: A Single-Blinded Randomized Controlled Trial.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:8

    Topics: Academic Medical Centers; Adult; Aged; Anesthetics, Local; Ankle Fractures; Bupivacaine; Female; Fol

2017
AnAnkle Trial study protocol: a randomised trial comparing pain profiles after peripheral nerve block or spinal anaesthesia for ankle fracture surgery.
    BMJ open, 2017, 06-02, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Ankle F

2017