Page last updated: 2024-10-24

bupivacaine and Alloxan Diabetes

bupivacaine has been researched along with Alloxan Diabetes in 8 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"Bupivacaine (Bup) has a certain research basis in pain-related diseases, but it has not been studied in painful diabetic neuropathy."1.62Low concentration of Bupivacaine ameliorates painful diabetic neuropathy by mediating miR-23a/PDE4B axis in microglia. ( Ju, F; Liao, O; Xia, L; Xie, A; Zhang, X; Zhou, Y, 2021)
"Subsequently, sufentanil induced hyperalgesia in diabetic and non-diabetic mice."1.42Beneficial effects of levobupivacaine regional anaesthesia on postoperative opioid induced hyperalgesia in diabetic mice. ( Blaes, N; Fourcade, O; Francès, B; Girolami, JP; Gomez-Brouchet, A; Minville, V; Mouledous, L; Tack, I, 2015)
"Levobupivacaine was more potent than lidocaine in all tests employed on diabetic rats."1.39Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy. ( Gunay, I; Gunes, Y; Mert, T, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Markova, L1
Umek, N1
Horvat, S1
Hadžić, A1
Kuroda, M1
Pintarič, TS1
Mrak, V1
Cvetko, E1
Zhang, X1
Xia, L1
Xie, A1
Liao, O1
Ju, F1
Zhou, Y1
Gomez-Brouchet, A1
Blaes, N1
Mouledous, L1
Fourcade, O1
Tack, I1
Francès, B1
Girolami, JP1
Minville, V1
Mert, T1
Gunes, Y1
Gunay, I1
Kroin, JS1
Buvanendran, A1
Tuman, KJ1
Kerns, JM1
Hung, CR1
Huang, EY1
Esmerino, LA1
Ranali, J1
Rodrigues, AL1
Imai, M1
Chang, KS1
Tanz, RD1
Stevens, WC1
Kemmotsu, O1

Other Studies

8 other studies available for bupivacaine and Alloxan Diabetes

ArticleYear
Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice.
    BMC veterinary research, 2020, Jul-17, Volume: 16, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fe

2020
Low concentration of Bupivacaine ameliorates painful diabetic neuropathy by mediating miR-23a/PDE4B axis in microglia.
    European journal of pharmacology, 2021, Jan-15, Volume: 891

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Blood Glucose; Bupivacaine; Cerebral Cortex; Cyclic N

2021
Beneficial effects of levobupivacaine regional anaesthesia on postoperative opioid induced hyperalgesia in diabetic mice.
    Journal of translational medicine, 2015, Jul-02, Volume: 13

    Topics: Analgesics, Opioid; Anesthesia, Conduction; Animals; Bupivacaine; Diabetes Mellitus, Experimental; H

2015
Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:2

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Disease Models, Animal; F

2013
Safety of local anesthetics administered intrathecally in diabetic rats.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:6

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Epinephrine; Injections,

2012
Role of acid back-diffusion in the formation of mucosal ulceration and its treatment with drugs in diabetic rats.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Atropine; Blood Glucose; Bupivacaine; Diabetes Mellitus, Experimental; D

1995
Blood glucose determination in normal and alloxan-diabetic rats after administration of local anesthetics containing vasoconstrictors.
    Brazilian dental journal, 1998, Volume: 9, Issue:1

    Topics: Alloxan; Analysis of Variance; Anesthetics, Local; Animals; Blood Glucose; Bupivacaine; Diabetes Mel

1998
[Enhanced myocardial depression from bupivacaine in diabetic rats].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:6

    Topics: Animals; Bupivacaine; Depression, Chemical; Diabetes Mellitus, Experimental; In Vitro Techniques; Ma

1991