bupivacaine has been researched along with Adverse Drug Event in 10 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lipid emulsion (LE) has been used to treat children with cardiovascular collapse induced by toxic doses of nonlocal anesthetics with high lipid solubility." | 3.01 | Lipid Emulsion Treatment for Drug Toxicity Caused by Nonlocal Anesthetic Drugs in Pediatric Patients: A Narrative Review. ( Kim, S; Lee, SH; Sohn, JT, 2023) |
| " Further studies are needed to determine the optimal dosing schedule of LE treatment for non-local anesthetic drug toxicity." | 3.01 | Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review. ( Lee, SH; Sohn, JT, 2023) |
| "0." | 1.35 | [Effects of lipid emulsion on hemodynamics and pharmacokinetics of mongrel dogs with bupivacaine-induced cardiac depression]. ( Chen, LM; Chen, Y; Liu, L; Wang, QG; Wang, WT; Wu, H; Xu, XZ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 6 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sohn, JT | 3 |
| Lee, SH | 2 |
| Kim, S | 1 |
| Haque, MM | 1 |
| Banik, D | 1 |
| Akhtaruzzaman, AK | 1 |
| Bhowmick, DK | 1 |
| Kader, MA | 1 |
| Reza, R | 1 |
| Morshed, MM | 1 |
| Hasanuzzaman, M | 1 |
| Azad, AK | 1 |
| Mariom, ML | 1 |
| Hossain, MS | 1 |
| Masud, M | 1 |
| Sultana, N | 1 |
| Zengin, EN | 1 |
| Zengin, M | 1 |
| Yiğit, H | 1 |
| Sazak, H | 1 |
| Şekerci, S | 1 |
| Alagöz, A | 1 |
| Abdel-Wahab, AH | 1 |
| Abd Alla, ES | 1 |
| Abd El-Azeem, T | 1 |
| Farzanegan, B | 1 |
| Zangi, M | 1 |
| Saeedi, K | 1 |
| Khalili, A | 1 |
| Rajabi, M | 1 |
| Jahangirifard, A | 1 |
| Emami, H | 1 |
| Mahboobipour, AA | 1 |
| Baniasadi, S | 1 |
| Golembiewski, J | 1 |
| Dasta, J | 1 |
| Wang, QG | 1 |
| Liu, L | 1 |
| Xu, XZ | 1 |
| Chen, LM | 1 |
| Chen, Y | 1 |
| Wang, WT | 1 |
| Wu, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Para-cervical Block Prior to Laparoscopic Hysterectomy as an Adjuvant Treatment to Reduce Postoperative Pain.[NCT03027661] | Phase 3 | 41 participants (Actual) | Interventional | 2017-08-01 | Completed | ||
| Liposomal Bupivacaine Versus Bupivacaine for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery.[NCT03036085] | Phase 2/Phase 3 | 200 participants (Anticipated) | Interventional | 2017-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Scale used is the Visual analogue scale for pain. Scale ranges from 0 being no pain, to 10 being worse pain ever experienced. (NCT03027661)
Timeframe: 30 minutes post-operative stop time
| Intervention | VAS scale 0-10 (Mean) |
|---|---|
| Control Group | 5.7 |
| Study Group | 3.2 |
Postoperative pain score on the Visual analgoue scale at 60 minutes from surgical stop time. Scale ranges from 0 being no pain, to 10 being worse pain ever experienced. (NCT03027661)
Timeframe: 60 minutes
| Intervention | VAS scale 0-10 (Mean) |
|---|---|
| Control Group | 5.9 |
| Study Group | 2.3 |
3 reviews available for bupivacaine and Adverse Drug Event
| Article | Year |
|---|---|
Lipid Emulsion Treatment for Drug Toxicity Caused by Nonlocal Anesthetic Drugs in Pediatric Patients: A Narrative Review.
Topics: Anesthetics, Local; Bupivacaine; Child; Drug-Related Side Effects and Adverse Reactions; Fat Emulsio | 2023 |
Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review.
Topics: Anesthetics, Local; Bupivacaine; Drug-Related Side Effects and Adverse Reactions; Fat Emulsions, Int | 2023 |
Evolving Role of Local Anesthetics in Managing Postsurgical Analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug-Related Side Effect | 2015 |
Evolving Role of Local Anesthetics in Managing Postsurgical Analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug-Related Side Effect | 2015 |
Evolving Role of Local Anesthetics in Managing Postsurgical Analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug-Related Side Effect | 2015 |
Evolving Role of Local Anesthetics in Managing Postsurgical Analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug-Related Side Effect | 2015 |
4 trials available for bupivacaine and Adverse Drug Event
| Article | Year |
|---|---|
Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Analgesia in Children Undergoing Infra-Umbilical Surgery.
Topics: Analgesia; Bangladesh; Bupivacaine; Child; Child, Preschool; Dexmedetomidine; Drug-Related Side Effe | 2023 |
Comparison of the effects of one-level and bi-level pre-incisional erector spinae plane block on postoperative acute pain in video-assisted thoracoscopic surgery; a prospective, randomized, double-blind trial.
Topics: Acute Pain; Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Cough; Drug-Related Side | 2023 |
Effect of intravenous dexamethasone on the duration of hyperbaric bupivacaine spinal anesthesia in lower abdominal surgery, Randomized controlled trial.
Topics: Administration, Intravenous; Adolescent; Adult; Anesthesia, Spinal; Bupivacaine; Dexamethasone; Drug | 2023 |
Effect of Adding Magnesium Sulphate to Epidural Bupivacaine and Morphine on Post-Thoracotomy Pain Management: A Randomized, Double-Blind, Clinical Trial.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics; Bupivacaine; Double-Blind Method; Drug Monitor | 2018 |
3 other studies available for bupivacaine and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Lipid emulsion dosage used for resuscitation after drug toxicity.
Topics: Anesthetics, Local; Bupivacaine; Drug-Related Side Effects and Adverse Reactions; Fat Emulsions, Int | 2022 |
[Effects of lipid emulsion on hemodynamics and pharmacokinetics of mongrel dogs with bupivacaine-induced cardiac depression].
Topics: Anesthetics, Local; Animals; Bupivacaine; Depression, Chemical; Dogs; Drug-Related Side Effects and | 2009 |