bupivacaine has been researched along with Acute Liver Injury, Drug-Induced in 11 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 7.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 3.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Bupivacaine is an established and efficacious anesthetic that has become increasingly popular in postoperative pain management." | 2.53 | Bupivacaine drug-induced liver injury: a case series and brief review of the literature. ( Chintamaneni, P; Malik, SM; Stevenson, HL, 2016) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Subirà González, A | 1 |
| Fernández Morales, M | 1 |
| Sánchez Royo, E | 1 |
| Boliart de San Félix, Y | 1 |
| Vila Lolo, C | 1 |
| Lee, JE | 1 |
| Kwak, KH | 1 |
| Chintamaneni, P | 1 |
| Stevenson, HL | 1 |
| Malik, SM | 1 |
| Wetmore, BA | 1 |
| Brees, DJ | 1 |
| Singh, R | 1 |
| Watkins, PB | 1 |
| Andersen, ME | 1 |
| Loy, J | 1 |
| Thomas, RS | 1 |
| Harper, MH | 1 |
| Johnson, BH | 1 |
| Eger, EI | 1 |
| Merin, RG | 1 |
| Brown, JL | 1 |
| Yokoyama, M | 1 |
| Ohashi, I | 1 |
| Nakatsuka, H | 1 |
| Mizobuchi, S | 1 |
| Toda, Y | 1 |
| Matsumi, M | 1 |
| Morita, K | 1 |
| Hirakawa, M | 1 |
1 review available for bupivacaine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Bupivacaine drug-induced liver injury: a case series and brief review of the literature.
Topics: Aged; Anesthetics, Local; Biopsy; Bupivacaine; Chemical and Drug Induced Liver Injury; Cholestasis; | 2016 |
10 other studies available for bupivacaine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Propofol infusion syndrome; are high doses always required?
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical | 2020 |
A liver transplant recipient with possible bupivacaine-induced liver injury caused by intra-articular injection after total knee arthroplasty: A case report.
Topics: Arthroplasty, Replacement, Knee; Bupivacaine; Chemical and Drug Induced Liver Injury; Humans; Inject | 2018 |
Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury.
Topics: Acetaminophen; Alanine Transaminase; Albumins; Analgesics, Non-Narcotic; Anesthetics, Local; Animals | 2010 |
Celiac plexus block does not alter hepatic injury in rats.
Topics: Anesthetics; Animals; Bupivacaine; Celiac Plexus; Chemical and Drug Induced Liver Injury; Drug Inter | 1984 |
Anesthesiology.
Topics: Anesthesiology; Anesthetics, Inhalation; Anesthetics, Local; Bupivacaine; Chemical and Drug Induced | 1998 |
Drug-induced liver disease during continuous epidural block with bupivacaine.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Chemical and Drug Ind | 2001 |