Page last updated: 2024-10-24

bupivacaine and Acute Hypercapnic Respiratory Failure

bupivacaine has been researched along with Acute Hypercapnic Respiratory Failure in 67 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"5% levobupivacaine would reduce occurrence of respiratory depression and hemidiaphragmatic paralysis."7.81[Levobupivacaine for Ultrasound-guided Interscalene Block: Block with 6 ml Leads to Less Occurrence of Respiratory Depression and Hemidiaphragmatic Paralysis]. ( Aishin, K; Hashimoto, M; Miyamoto, S; Nakamura, T, 2015)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."7.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
" Intrathecal morphine prolongs analgesia after surgery, but has been implicated in nausea and vomiting, pruritus, postoperative respiratory depression, or apneic episodes."5.51Comparison of low-dose morphine intrathecal analgesia and sufentanil PCIA in elderly patients with hip fracture undergoing single spinal anesthesia - a randomized clinical trial. ( Guo, K; Jin, F; Liang, D; Liu, Y; Tang, Z; Xu, Z; Yang, X; Yao, J, 2022)
"5% levobupivacaine would reduce occurrence of respiratory depression and hemidiaphragmatic paralysis."3.81[Levobupivacaine for Ultrasound-guided Interscalene Block: Block with 6 ml Leads to Less Occurrence of Respiratory Depression and Hemidiaphragmatic Paralysis]. ( Aishin, K; Hashimoto, M; Miyamoto, S; Nakamura, T, 2015)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."3.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
"5-year-old child with Cornelia de Lange syndrome presenting for orchidopexy and herniotomy received general anaesthesia which was supplemented by a caudal injection of bupivacaine."3.67Respiratory arrest after a caudal injection of bupivacaine. ( Carli, F; Lumb, AB, 1989)
"75% bupivacaine, and of 2% lidocaine and one ampule of hyaluronidase for cataract extraction, the patient sustained bilateral opthalmoplegia, blindness, central respiratory arrest, and loss of consciousness."3.67Life-threatening complication of retrobulbar block. A hypothesis. ( Brookshire, GL; Gleitsmann, KY; Schenk, EC, 1986)
"Moderate to severe respiratory depression was detected in 14 patients more than 2 h after operation."2.68Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain. ( Heinonen, J; Hirvisalo, EL; Kalso, E; Nilsson, E; Perttunen, K; Salo, JA, 1995)
"The overall incidence of respiratory depression was 17."1.39Transcutaneous carbon dioxide levels and oxygen saturation following caesarean section performed under spinal anaesthesia with intrathecal opioids. ( Binning, A; Dalchow, S; Duggan, T; Harvey, A; Lubeigt, O; Peters, G, 2013)
"Diastrophic dwarfism is a rare disease in which pregnancy is uncommon."1.34Anaesthesia for Caesarean section in a patient with diastrophic dwarfism. ( Mendonca, C; Porter, M, 2007)
"The first patient had a cardiac arrest whereas the second developed respiratory failure and altered neurological status."1.32Two cases of hemorrhage secondary to amniotic fluid embolus managed with uterine artery embolization. ( Davies, S; Goldszmidt, E, 2003)
"We present a patient with a large pulmonary hydatid cyst compressing underlying lung, with previous pulmonary tuberculosis, who presented in respiratory failure."1.31Excision of a giant hydatid cyst of the lung under thoracic epidural anaesthesia. ( De Groot, KM; Dyer, RA; Gordon, PC; James, MF; Walther, G, 2001)
"Case 1: A 72-year-old 84-kg white man with cancer of the bladder and bone metastases had intense back and leg pain that was treated with intrathecal morphine for 6 months at an increasing dosage up to 10 mg twice daily."1.30Respiratory depression following administration of intrathecal bupivacaine to an opioid-dependent patient. ( Barjhoux, CE; Danel, VC; Lemoigne, AH; Mallaret, MP; Piquet, CY; Vincent, FH, 1998)
"We prospectively studied surgical cancer patients who received epidural bupivacaine-morphine to determine perioperative morphine use, side effects, and complications."1.29Postoperative epidural bupivacaine-morphine therapy. Experience with 4,227 surgical cancer patients. ( de Leon-Casasola, OA; Harrison, P; Lema, MJ; Massey, J; Parker, B, 1994)
"Urinary retention was seen in 11% of patients and pruritus in 10%."1.29An audit of extradural infusion analgesia in children using bupivacaine and diamorphine. ( Lloyd-Thomas, AR; Wilson, PT, 1993)
" This work suggests that the lethal cardiorespiratory toxicity of lidocaine and bupivacaine associated with intravenous infusion is additively toxic in rats."1.28Lidocaine and bupivacaine cardiorespiratory toxicity is additive: a study in rats. ( Erskine, R; James, MF; Janicki, PK; Mets, B; Sasman, B, 1992)
"A case is reported of acute respiratory failure occurring during upper abdominal surgery in a patient not previously known to have chronic respiratory failure."1.28[Transient acute respiratory failure and thoracic epidural anesthesia]. ( Joyau, FH; Maries, H, 1989)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199023 (34.33)18.7374
1990's23 (34.33)18.2507
2000's13 (19.40)29.6817
2010's6 (8.96)24.3611
2020's2 (2.99)2.80

Authors

AuthorsStudies
Xu, Z1
Tang, Z1
Yao, J1
Liang, D1
Jin, F1
Liu, Y1
Guo, K1
Yang, X1
Rhyner, P1
Kirkham, K1
Hirotsu, C1
Farron, A1
Albrecht, E1
Dalchow, S1
Lubeigt, O1
Peters, G1
Harvey, A1
Duggan, T1
Binning, A1
Chiavaccini, L1
Claude, AK1
Meyer, RE1
Wan Mat, WR1
Yahya, N1
Izaham, A1
Abdul Rahman, R1
Abdul Manap, N1
Md Zain, J1
Busardò, FP1
Tritapepe, L1
Montana, A1
Indorato, F1
Zaami, S1
Romano, G1
Shaaban, M1
Esa, WA1
Maheshwari, K1
Elsharkawy, H1
Soliman, LM1
Nakamura, T1
Miyamoto, S1
Aishin, K1
Hashimoto, M1
Maman, AO1
Ahouangbévi, S2
Chobli, M2
Aouad, MT1
Moukaddem, FH1
Akel, SR1
Kanazi, GE1
Kuczkowski, KM1
Kehl, F1
Erfkamp, S1
Roewer, N1
Goldszmidt, E1
Davies, S1
Delcourt, J1
Barré, J1
Lelarge, C1
Payen, M1
Malinovsky, JM1
Biswas, BK1
Singh, SN1
Agarwal, B1
Sah, BP1
Chaturvedi, A1
Banerjee, B1
Ouro-Bang'na Maman, AF1
Maman, AF1
Porter, M1
Mendonca, C1
Smith, JL2
Beltranena, HP1
Vega, MJ1
Garcia, JJ1
Blankenship, G1
Burden, AL1
Hathaway, EG1
Davies, GK1
Tolhurst-Cleaver, CL1
James, TL1
Holmboe, J1
Kongsrud, F1
Reynolds, F1
Lauckner, ME1
Barratt, P1
Headland, RM1
Perttunen, K1
Nilsson, E1
Heinonen, J1
Hirvisalo, EL1
Salo, JA1
Kalso, E1
de Leon-Casasola, OA1
Parker, B1
Lema, MJ1
Harrison, P1
Massey, J1
Wilson, PT1
Lloyd-Thomas, AR1
Stienstra, R1
Pannekoek, BJ1
Mayer, AS1
O'Connor, RE1
Greenhalgh, CA1
Jerez, A1
Molina, JA1
Benito-León, J1
Kapral, S1
Krafft, P1
Gosch, M1
Fridrich, P1
Weinstabl, C1
Piquet, CY1
Mallaret, MP1
Lemoigne, AH1
Barjhoux, CE1
Danel, VC1
Vincent, FH1
Alsahaf, MH1
Stockwell, M1
Wigfull, J1
Welchew, E1
Dyer, RA1
Gordon, PC1
De Groot, KM1
Walther, G1
James, MF2
Ehikhametalor, KO1
Nelson, M1
Knoblanche, GE1
Maycock, E1
Koeberle, P1
Bourion, P1
Bettinger, G1
Barale, F1
Pedersen, T1
Viby-Mogensen, J1
Ringsted, C1
Mets, B1
Janicki, PK1
Erskine, R1
Sasman, B1
Hobbs, GJ1
Roberts, FL1
Cohen, SM1
Sousa, FJ1
Kelly, NE1
Wendel, RT1
Wolf, AR1
Walker, SM1
Smart, NG1
Gibson, P1
Murrell, D1
Weightman, WM1
Paech, M1
Dragich, DA1
Ross, AF1
Chestnut, DH1
Wenstrom, K1
Lee, E1
Collins, G1
Morishima, HO2
Finster, M2
Arthur, GR2
Covino, BG2
Lumb, AB1
Carli, F1
McClure, JH1
Jones, G1
Fortuna, A1
Maries, H1
Joyau, FH1
Koenig, SB1
Snyder, RW1
Kay, J1
Simonsen, L1
Nygård, E1
Kobet, KA1
Wittpenn, JR1
Rapoza, P1
Sternberg, P1
Kuwashima, L1
Saklad, J1
Patz, A1
Brookshire, GL1
Gleitsmann, KY1
Schenk, EC1
Pedersen, H1
Hiraoka, H1
Tsuji, A1
Feldman, HS1
Pflug, AE1
Murphy, TM1
Butler, SH1
Tucker, GT1
Nolte, H1
Meyer, J1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Ultrasound-Guided Quadratus Lumborum Block and Epidural Analgesia for Postoperative Pain Management After Renal Transplantation[NCT03771339]50 participants (Actual)Interventional2018-12-10Completed
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section[NCT03199170]90 participants (Actual)Interventional2017-09-01Completed
Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to Placebo[NCT04887649]Phase 3114 participants (Actual)Interventional2009-03-31Completed
The Comparison of the Analgesic Efficacy and Hemodynamic Effects of Paravertebral Block Compared With Paravertebral and Intercostal Nerve Block for Thoracotomy in Adults: A Randomized Controlled Trail[NCT04715880]70 participants (Actual)Interventional2021-02-15Completed
Comparison Of Ultrasound-Assisted Paravertebral Block And Traditional Paravertebral Block For Pain Control After Thoracic Surgery, A Prospective Randomized Trial[NCT01949480]45 participants (Actual)Interventional2013-07-01Completed
Assessment of Hemi-diaphragm Dysfunction After Upper Extremity Nerve Blocks Using Passive Oscillometry to Measure Lung Mechanics - A Pilot Study.[NCT04005235]19 participants (Actual)Observational2019-07-31Terminated (stopped due to Covid-19 pandemic, aerosol generating procedures)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Forced Expiratory Volume in 1 Sec (FEV1)

Forced expiratory volume in 1 sec (FEV1) preoperatively and at 24 - hour interval. Then the values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively

Interventionpercentage in change from per-surgery (Mean)
Traditional Approach Paravertebral Nerve Block0.561
Ultrasound Assisted Paravertebral Nerve Block0.571

Forced Vital Capacity (FVC)

Forced vital capacity (FVC) measured preoperatively and at 24 - hour interval. Then values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively

Interventionpercentage in change from per-surgery (Mean)
Traditional Approach Paravertebral Nerve Block0.551
Ultrasound Assisted Paravertebral Nerve Block0.504

Incentive Spirometry

Inspiratory Volume as measured by incentive spirometer preoperatively and at 24 hours post PCA initiation. The data is reported as a percentage in change from per-surgery measurements (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and Postoperatively

Interventionpercentage in change from per-surgery (Mean)
Traditional Approach Paravertebral Nerve Block0.658
Ultrasound Assisted Paravertebral Nerve Block0.716

Inspired Oxygen Concentration and Blood Oxygen Saturation (SpO2)

Inspired oxygen concentration and SpO2 preoperatively and at 24 - hour interval. Value reported is an average of the preoperative and the 24-hour postoperative SpO2 measurements. (NCT01949480)
Timeframe: Pre-operatively and at 24 hour post-operative

InterventionPercentage of SpO2 (Mean)
Traditional Approach Paravertebral Nerve Block95
Ultrasound Assisted Paravertebral Nerve Block94

Number of Local Anesthetic Boluses Requested by PCA

The number of local anesthetic boluses over 24- hour period post PCA initiation will also be recorded. (NCT01949480)
Timeframe: 24 hours postoperatively

InterventionNumber of boluses requested (Mean)
Traditional Approach Paravertebral Nerve Block27.5
Ultrasound Assisted Paravertebral Nerve Block48

Opioid Consumption at 24 Hours Postoperatively

Hydromorphone (Dilaudid) consumption or opiate equivalent at 24-hour interval post PCA initiation at the post-anesthesia care unit (PACU). (NCT01949480)
Timeframe: 24 hours after patient-controlled analgesia (PCA) was initiated

Interventionmg (Mean)
Traditional Approach Paravertebral Nerve Block5.75
Ultrasound Assisted Paravertebral Nerve Block6.38

Peak Expiratory Flow Rate(PEF)

Peak expiratory flow rate preoperatively (PEF) and at 24 - hour interval. Then values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively

Interventionpercentage in change from per-surgery (Mean)
Traditional Approach Paravertebral Nerve Block0.568
Ultrasound Assisted Paravertebral Nerve Block0.542

Respiratory Rate

Respiratory rate (RR) per minute after surgery. (NCT01949480)
Timeframe: 24 hours postoperatively

Interventionbreaths per one minute (Mean)
Traditional Approach Paravertebral Nerve Block17
Ultrasound Assisted Paravertebral Nerve Block17.7

Sensory Level

Sensory level as assessed by temperature and pin prick test assessed every 5 min for 30 min after nerve block as defined as the patient returning to their bed. Data below are in number of patients who didn't have any change during the ice and pin prik test. (NCT01949480)
Timeframe: 6 assessments starting 5 minutes after nerve block and ending 30 minutes after nerve block.

InterventionParticipants (Count of Participants)
Traditional Approach Paravertebral Nerve Block3
Ultrasound Assisted Paravertebral Nerve Block1

Total Local Anesthetic Infusions Over 24- Hour Period

The total local anesthetic infusions over 24- hour period. (NCT01949480)
Timeframe: 24 hours postoperatively

InterventionmL (Mean)
Traditional Approach Paravertebral Nerve Block173
Ultrasound Assisted Paravertebral Nerve Block186

Total Number of Local Anesthetic Boluses in 24 Hours

Total Number of Local Anesthetic bolus doses given within the 24-hours post-operatively. (NCT01949480)
Timeframe: postoperatively, up to 24 hours

Interventionnumber of boluses (Mean)
Traditional Approach Paravertebral Nerve Block1
Ultrasound Assisted Paravertebral Nerve Block2

Pain 11-point Numerical Rating Scale (NRS)at Rest and With Deep Breathing

The pain level assessed using an 11-point numerical rating scale (NRS) with 0 indicating no pain and 10 indicating the worst pain possible with deep breathing and rest at 24 hours post PCA initiation. (NCT01949480)
Timeframe: 24 hours post PCA initiation

,
Interventionunits on a scale (Mean)
NRS at rest after 24 hrsNRS during deep inspiration at 24 hrs
Traditional Approach Paravertebral Nerve Block1.734
Ultrasound Assisted Paravertebral Nerve Block2.924.77

Trials

4 trials available for bupivacaine and Acute Hypercapnic Respiratory Failure

ArticleYear
Comparison of low-dose morphine intrathecal analgesia and sufentanil PCIA in elderly patients with hip fracture undergoing single spinal anesthesia - a randomized clinical trial.
    BMC anesthesiology, 2022, 04-27, Volume: 22, Issue:1

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Bupivacaine; Delirium;

2022
A randomised controlled trial of shoulder block vs. interscalene brachial plexus block for ventilatory function after shoulder arthroscopy.
    Anaesthesia, 2020, Volume: 75, Issue:4

    Topics: Adult; Anesthetics, Local; Arthroscopy; Brachial Plexus Block; Bupivacaine; Female; Humans; Male; Ne

2020
Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Drug Administration Sch

1995
Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Drug Administration Sch

1995
Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Drug Administration Sch

1995
Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Drug Administration Sch

1995
Intrathecal pethidine as sole anaesthetic agent for operative procedures of the lower limb, inguinal area and perineum.
    The West Indian medical journal, 2001, Volume: 50, Issue:4

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Lo

2001

Other Studies

63 other studies available for bupivacaine and Acute Hypercapnic Respiratory Failure

ArticleYear
Transcutaneous carbon dioxide levels and oxygen saturation following caesarean section performed under spinal anaesthesia with intrathecal opioids.
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivaca

2013
An anesthetic protocol for adult heartworms removal in two cases of canine caval syndrome.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:1

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Bupivacaine; Butorpha

2014
Near fatal error in management of postoperative epidural analgesia.
    The International journal of risk & safety in medicine, 2014, Volume: 26, Issue:2

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fentanyl; Hu

2014
A fatal accidental subarachnoid injection of lidocaine and levobupivacaine during a lumbar paravertebral block.
    Forensic science international, 2015, Volume: 256

    Topics: Anesthetics, Local; Bupivacaine; Fatal Outcome; Female; Heart Arrest; Humans; Injections; Levobupiva

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
[Levobupivacaine for Ultrasound-guided Interscalene Block: Block with 6 ml Leads to Less Occurrence of Respiratory Depression and Hemidiaphragmatic Paralysis].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:7

    Topics: Adult; Aged; Anesthetics, Local; Brachial Plexus; Bupivacaine; Female; Humans; Levobupivacaine; Male

2015
[Respiratory depression after intrathecal injection of tramadol with hyperbaric bupivacaine].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:11

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; Humans; Injections, Spinal

2006
Respiratory failure in a former preterm infant following high spinal anesthesia with bupivacaine and clonidine.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:10

    Topics: Adrenergic alpha-Agonists; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Clonidine; Humans; I

2008
Respiratory arrest in a parturient following intrathecal administration of fentanyl and bupivacaine as part of a combined spinal-epidural analgesia for labour.
    Anaesthesia, 2002, Volume: 57, Issue:9

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2002
Respiratory arrest during caesarean section after intrathecal administration of sufentanil in combination with 0.1% bupivacaine 10 ml.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Combined; Bupivacaine; Cesarean Section; Female; Humans

2002
Two cases of hemorrhage secondary to amniotic fluid embolus managed with uterine artery embolization.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:9

    Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics,

2003
Delayed respiratory depression after interscalene blockade for shoulder surgery in geriatric patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:1

    Topics: Aged; Aged, 80 and over; Amides; Anesthetics, Local; Brachial Plexus; Bupivacaine; Female; Humans; I

2006
Respiratory failure after lumbar epidural anesthesia in a patient with uncontrolled hyperthyroidism.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Abdomen; Aged; Anesthesia, Epidural; Bupivacaine; Female; Humans; Hyperthyroidism; Laparoscopy; Resp

2006
[Respiratory depression after intrathecal injection of tramadol with hyperbaric bupivacaine].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:11

    Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Calcinosis; Female; Humans; Injections, Spinal;

2006
Anaesthesia for Caesarean section in a patient with diastrophic dwarfism.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:2

    Topics: Adult; Airway Obstruction; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Intravenous;

2007
Retrobulbar marcaine can cause respiratory arrest.
    Journal of clinical neuro-ophthalmology, 1981, Volume: 1, Issue:3

    Topics: Bupivacaine; Eye; Humans; Injections; Respiratory Insufficiency

1981
Complications of retrobulbar marcaine injection.
    Journal of clinical neuro-ophthalmology, 1982, Volume: 2, Issue:3

    Topics: Adult; Aged; Bupivacaine; Cataract Extraction; Diabetic Retinopathy; Female; Humans; Injections; Mal

1982
Respiratory arrest after retrobulbar bupivicaine.
    Annals of ophthalmology, 1983, Volume: 15, Issue:12

    Topics: Bupivacaine; Female; Humans; Nerve Block; Respiratory Insufficiency

1983
Respiratory arrest following bupivicaine retrobulbar block.
    Annals of ophthalmology, 1983, Volume: 15, Issue:12

    Topics: Aged; Bupivacaine; Cataract Extraction; Cheyne-Stokes Respiration; Humans; Male; Nerve Block; Respir

1983
Respiratory depression after intrathecal narcotics.
    Anaesthesia, 1980, Volume: 35, Issue:11

    Topics: Adult; Aged; Analgesia; Anesthesia, Spinal; Bupivacaine; Female; Humans; Injections, Spinal; Male; M

1980
Delayed respiratory arrest after bupivacaine.
    Anaesthesia, 1982, Volume: 37, Issue:1

    Topics: Anesthesia, Epidural; Bupivacaine; Hernia, Inguinal; Humans; Male; Middle Aged; Muscular Diseases; P

1982
Delayed respiratory arrest after epidural bupivacaine.
    Anaesthesia, 1982, Volume: 37, Issue:5

    Topics: Anesthesia, Epidural; Bupivacaine; Humans; Respiratory Insufficiency

1982
Delayed respiratory arrest after bupivacaine.
    Anaesthesia, 1982, Volume: 37, Issue:6

    Topics: Bupivacaine; Humans; Intraoperative Complications; Male; Middle Aged; Nerve Block; Respiratory Insuf

1982
Retrobulbar bupivacaine can cause respiratory arrest.
    Annals of ophthalmology, 1982, Volume: 14, Issue:11

    Topics: Anesthesia; Bupivacaine; Humans; Respiration, Artificial; Respiratory Insufficiency

1982
Respiratory depression associated with spinal narcotic anaesthesia.
    The Medical journal of Australia, 1995, Oct-02, Volume: 163, Issue:7

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Humans;

1995
Postoperative epidural bupivacaine-morphine therapy. Experience with 4,227 surgical cancer patients.
    Anesthesiology, 1994, Volume: 81, Issue:2

    Topics: Adult; Aged; Analgesia, Epidural; Bupivacaine; Catheters, Indwelling; Drug Combinations; Female; Hum

1994
An audit of extradural infusion analgesia in children using bupivacaine and diamorphine.
    Anaesthesia, 1993, Volume: 48, Issue:8

    Topics: Adolescent; Analgesia, Epidural; Bupivacaine; Child; Child, Preschool; Heroin; Humans; Infant; Infan

1993
Respiratory arrest following extradural sufentanil.
    Anaesthesia, 1993, Volume: 48, Issue:12

    Topics: Adult; Anesthesia, Epidural; Bupivacaine; Humans; Male; Postoperative Complications; Respiratory Ins

1993
Respiratory arrest after local anesthesia for outpatient cataract surgery: a dramatic but transient complication.
    Annals of emergency medicine, 1993, Volume: 22, Issue:8

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Bupivacaine; Female; Humans; Hyaluronogluco

1993
Respiratory arrest in a parturient following intrathecal injection of sufentanil and bupivacaine.
    Anaesthesia, 1996, Volume: 51, Issue:2

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

1996
Epidural anesthesia.
    Neurology, 1997, Volume: 48, Issue:1

    Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Coma; Embolism, Air; Female; Heart Arre

1997
[Subdural, extra-arachnoid block as a complication of stellate ganglion block: documentation with ultrasound].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1997, Volume: 32, Issue:10

    Topics: Adult; Anesthetics, Local; Arm Injuries; Autonomic Nerve Block; Blast Injuries; Bupivacaine; Humans;

1997
Respiratory depression following administration of intrathecal bupivacaine to an opioid-dependent patient.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug Interactions; Fat

1998
Respiratory failure due to the combined effects of transdermal fentanyl and epidural bupivacaine/diamorphine following radical nephrectomy.
    Journal of pain and symptom management, 2000, Volume: 20, Issue:3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Fentanyl; Hero

2000
Survey of 1057 patients receiving postoperative patient-controlled epidural analgesia.
    Anaesthesia, 2001, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Anal

2001
Excision of a giant hydatid cyst of the lung under thoracic epidural anaesthesia.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:2

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Echinococcosis,

2001
The incidence and aetiology of phrenic nerve blockade associated with supraclavicular brachial plexus block.
    Anaesthesia and intensive care, 1979, Volume: 7, Issue:4

    Topics: Adult; Aged; Anesthesia, Local; Brachial Plexus; Bupivacaine; Diaphragm; Female; Humans; Male; Middl

1979
An epidural anaesthetic with unusual complications.
    Anaesthesia and intensive care, 1978, Volume: 6, Issue:3

    Topics: Anesthesia, Epidural; Bupivacaine; Female; Humans; Respiratory Insufficiency; Time Factors

1978
[Postoperative analgesia by intrathecal morphine and respiratory depression: value of low doses (apropos of 285 cases)].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1992, Volume: 33 Spec No 1

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Spinal; Bupivacaine; Dose-Response Relationsh

1992
Anaesthetic practice and postoperative pulmonary complications.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:8

    Topics: Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthesia, Conduction; Anesthesia, General; A

1992
Lidocaine and bupivacaine cardiorespiratory toxicity is additive: a study in rats.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:4

    Topics: Animals; Bupivacaine; Drug Synergism; Heart Arrest; Infusions, Intravenous; Lidocaine; Male; Rats; R

1992
Epidural infusion of bupivacaine and diamorphine for postoperative analgesia. Use on general surgical wards.
    Anaesthesia, 1992, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Female; Heroin; Humans

1992
Respiratory arrest and new retinal hemorrhages after retrobulbar anesthesia.
    American journal of ophthalmology, 1992, Feb-15, Volume: 113, Issue:2

    Topics: Adult; Anesthesia, Local; Bupivacaine; Humans; Lidocaine; Male; Middle Aged; Needles; Orbit; Respira

1992
Development of a high block in an infant during an epidural bupivacaine infusion.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Analgesia, Epidural; Anesthesia, Epidural; Bradycardia; Bupivacaine; Humans; Infant; Kidney; Male; R

1991
Epidural LA/opioid.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Analgesia, Epidural; Apnea; Bupivacaine; Fentanyl; Humans; Lumbar Vertebrae; Respiratory Insufficien

1991
Complications of epidural analgesia.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Adult; Analgesia, Epidural; Apnea; Bupivacaine; Child; Fentanyl; Humans; Infant; Respiratory Insuffi

1991
Respiratory arrest during epidural infusion of bupivacaine and fentanyl.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:2

    Topics: Aged; Analgesia, Epidural; Bupivacaine; Female; Fentanyl; Humans; Male; Middle Aged; Pain, Postopera

1991
Epidural bupivacaine-fentanyl infusions.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Analgesia, Epidural; Apnea; Bupivacaine; Fentanyl; Humans; Respiratory Insufficiency

1991
Respiratory failure associated with amnioinfusion during labor.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:4

    Topics: Adult; Amnion; Analgesia, Obstetrical; Bupivacaine; Female; Humans; Infusions, Intravenous; Labor, I

1991
Respiratory arrest after caudal bupivacaine.
    Anaesthesia, 1990, Volume: 45, Issue:1

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Child, Preschool; Humans; Male; Respiratory I

1990
Pregnancy does not alter lidocaine toxicity.
    American journal of obstetrics and gynecology, 1990, Volume: 162, Issue:5

    Topics: Animals; Blood Pressure; Bupivacaine; Female; Heart Rate; Hypotension; Lidocaine; Mepivacaine; Pregn

1990
Respiratory arrest after a caudal injection of bupivacaine.
    Anaesthesia, 1989, Volume: 44, Issue:4

    Topics: Anesthesia, Epidural; Bupivacaine; Child, Preschool; Cryptorchidism; De Lange Syndrome; Hernia, Ingu

1989
Comparison of bupivacaine and bupivacaine with fentanyl in continuous extradural analgesia during labour.
    British journal of anaesthesia, 1989, Volume: 63, Issue:5

    Topics: Analgesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Female; Fentanyl; Humans; Pregnancy; Resp

1989
Respiratory arrest after a caudal injection of bupivacaine.
    Anaesthesia, 1989, Volume: 44, Issue:12

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Child; Humans; Respiratory Insufficiency

1989
[Transient acute respiratory failure and thoracic epidural anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:2

    Topics: Acute Disease; Anesthesia, Epidural; Bupivacaine; Female; Fentanyl; Horner Syndrome; Humans; Intraop

1989
Respiratory distress after a Nadbath block.
    Ophthalmology, 1988, Volume: 95, Issue:9

    Topics: Aged; Bupivacaine; Cough; Deglutition Disorders; Facial Nerve; Female; Hoarseness; Humans; Lidocaine

1988
[Cardiovascular collapse following intercostal blockade with bupivacaine].
    Ugeskrift for laeger, 1987, Oct-26, Volume: 149, Issue:44

    Topics: Bupivacaine; Humans; Hypersensitivity, Immediate; Hypotension; Intercostal Nerves; Male; Middle Aged

1987
Cerebral spinal fluid recovery of lidocaine and bupivacaine following respiratory arrest subsequent to retrobulbar block.
    Ophthalmic surgery, 1987, Volume: 18, Issue:1

    Topics: Aged; Anesthesia, Local; Bupivacaine; Eye; Humans; Injections; Kinetics; Lidocaine; Male; Respirator

1987
Respiratory arrest following retrobulbar anesthesia.
    Ophthalmology, 1986, Volume: 93, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Bupivacaine; Female; Humans; Injections; Lidocain

1986
Life-threatening complication of retrobulbar block. A hypothesis.
    Ophthalmology, 1986, Volume: 93, Issue:11

    Topics: Blindness; Bupivacaine; Cataract Extraction; Eye; Humans; Male; Middle Aged; Nerve Block; Ophthalmop

1986
Bupivacaine toxicity in pregnant and nonpregnant ewes.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Animals; Blood Pressure; Bupivacaine; Dose-Response Relationship, Drug; Etidocaine; Female; Fetus; H

1985
The effects of postoperative peridural analgesia on pulmonary therapy and pulmonary complications.
    Anesthesiology, 1974, Volume: 41, Issue:1

    Topics: Analgesia; Breathing Exercises; Bupivacaine; Convalescence; Female; Humans; Male; Nerve Block; Pain,

1974
[The possibilities of indications for regional anaesthesia].
    Der Anaesthesist, 1972, Volume: 21, Issue:3

    Topics: Ambulatory Care; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Local; Angiography; B

1972