bupivacaine has been researched along with Acidosis, Respiratory in 6 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Acidosis, Respiratory: Respiratory retention of carbon dioxide. It may be chronic or acute.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that acidosis can increase the toxicity of bupivacaine more than that of lidocaine by increasing the distribution into the brain, myocardium, or both, studies were performed to measure the in vivo tissue:blood partition coefficients during continuous steady state intravenous infusions of these agents in anesthetized sheep during normal acid-base status and during combined respiratory-metabolic acidosis." | 7.67 | The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep. ( Mather, LE; Nancarrow, C; Plummer, JL; Runciman, WB; Upton, RN, 1987) |
| "To test the hypothesis that acidosis can increase the toxicity of bupivacaine more than that of lidocaine by increasing the distribution into the brain, myocardium, or both, studies were performed to measure the in vivo tissue:blood partition coefficients during continuous steady state intravenous infusions of these agents in anesthetized sheep during normal acid-base status and during combined respiratory-metabolic acidosis." | 3.67 | The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep. ( Mather, LE; Nancarrow, C; Plummer, JL; Runciman, WB; Upton, RN, 1987) |
| "Acute respiratory acidosis (pHa 7." | 1.30 | The effects of bupivacaine and ropivacaine on baroreflex sensitivity with or without respiratory acidosis and alkalosis in rats. ( Dohi, S; Iida, H; Ishiyama, T; Watanabe, Y, 1997) |
| "Serious arrhythmias (ventricular or supraventricular tachycardia) were noted in all groups, but the incidence was significantly higher in the group of rats given diazepam pretreatment than in the other three groups." | 1.27 | Does diazepam really reduce the cardiotoxic effects of intravenous bupivacaine? ( Denson, DD; Forsberg, T; Gregg, RV; Sehlhorst, CS; Stuebing, RC; Turner, PA, 1988) |
| "The conclusion of this study was that a respiratory acidosis increased the central nervous system toxicity of local anaesthetics and that the underlying metabolic conditions modified this increase." | 1.25 | Central nervous system effects of local anaesthetic agents. ( Englesson, S; Matousek, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biscoping, J | 1 |
| Salomon, F | 1 |
| Hempelmann, G | 1 |
| Watanabe, Y | 1 |
| Dohi, S | 1 |
| Iida, H | 1 |
| Ishiyama, T | 1 |
| Englesson, S | 1 |
| Matousek, M | 1 |
| Gregg, RV | 1 |
| Turner, PA | 1 |
| Denson, DD | 1 |
| Stuebing, RC | 1 |
| Sehlhorst, CS | 1 |
| Forsberg, T | 1 |
| Nancarrow, C | 1 |
| Runciman, WB | 1 |
| Mather, LE | 1 |
| Upton, RN | 1 |
| Plummer, JL | 1 |
| Rosen, MA | 1 |
| Thigpen, JW | 1 |
| Shnider, SM | 1 |
| Foutz, SE | 1 |
| Levinson, G | 1 |
| Koike, M | 1 |
6 other studies available for bupivacaine and Acidosis, Respiratory
| Article | Year |
|---|---|
[Plasma levels following lumbar epidural anesthesia with 0.75% bupivacaine].
Topics: Acidosis, Respiratory; Aged; Anesthesia, Epidural; Bupivacaine; Hip Prosthesis; Humans; Lumbosacral | 1984 |
The effects of bupivacaine and ropivacaine on baroreflex sensitivity with or without respiratory acidosis and alkalosis in rats.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Amides; Anesthetics, Local; Animals; Baroreflex; Bloo | 1997 |
Central nervous system effects of local anaesthetic agents.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Allyl Compounds; Amines; Anesthetics, Local; Anilides; | 1975 |
Does diazepam really reduce the cardiotoxic effects of intravenous bupivacaine?
Topics: Acidosis, Respiratory; Animals; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Bupivacain | 1988 |
The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep.
Topics: Acidosis; Acidosis, Respiratory; Animals; Brain; Bupivacaine; Female; Hydrogen-Ion Concentration; Li | 1987 |
Bupivacaine-induced cardiotoxicity in hypoxic and acidotic sheep.
Topics: Acidosis, Respiratory; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Dose-Response Rel | 1985 |