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bunazosin and Renal Insufficiency

bunazosin has been researched along with Renal Insufficiency in 2 studies

bunazosin: structure

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetics and pharmacodynamics of the alpha ( 1 ) -blocker bunazosin were studied in 9 patients with renal insufficiency and 11 healthy control subjects after a single oral administration of 3 mg."9.09Pharmacokinetics and pharmacodynamics of bunazosin in patients with renal insufficiency. ( Koike, Y; Mineshita, S; Mizoguchi, H; Nomura, Y, 1999)
"The pharmacokinetics and pharmacodynamics of the alpha ( 1 ) -blocker bunazosin were studied in 9 patients with renal insufficiency and 11 healthy control subjects after a single oral administration of 3 mg."5.09Pharmacokinetics and pharmacodynamics of bunazosin in patients with renal insufficiency. ( Koike, Y; Mineshita, S; Mizoguchi, H; Nomura, Y, 1999)
"Bunazosin Retard was associated with increases in GFR and ERPF in both normal and renally impaired groups; the increases were statistically significant in the renally impaired group (n = 14)."2.67Renal haemodynamic effects of bunazosin retard and prazosin in mild to moderately hypertensive patients with normal or moderately impaired renal function. ( Anderton, JL; Gill, M; Notghi, A, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderton, JL1
Gill, M1
Notghi, A1
Koike, Y1
Mineshita, S1
Mizoguchi, H1
Nomura, Y1

Trials

2 trials available for bunazosin and Renal Insufficiency

ArticleYear
Renal haemodynamic effects of bunazosin retard and prazosin in mild to moderately hypertensive patients with normal or moderately impaired renal function.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:6

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Female; Glomerular Filtration

1994
Pharmacokinetics and pharmacodynamics of bunazosin in patients with renal insufficiency.
    American journal of therapeutics, 1999, Volume: 6, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Area Under Curve; Dose-Response Relationship, Drug; Femal

1999