bunazosin has been researched along with Prostatic Hyperplasia in 12 studies
bunazosin: structure
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-five patients with prostatic hyperplasia were entered into a randomized controlled study using bunazosin hydrochloride(alpha 1-adrenergic blocker)." | 9.07 | [The evaluation of the effects of bunazosin hydrochloride in the treatment of prostatic hyperplasia]. ( Asano, H; Fujita, T; Hirabayashi, S; Kato, N; Kinukawa, T; Ohshima, S; Ono, Y, 1992) |
| "Thirty-five patients with prostatic hyperplasia were entered into a randomized controlled study using bunazosin hydrochloride(alpha 1-adrenergic blocker)." | 5.07 | [The evaluation of the effects of bunazosin hydrochloride in the treatment of prostatic hyperplasia]. ( Asano, H; Fujita, T; Hirabayashi, S; Kato, N; Kinukawa, T; Ohshima, S; Ono, Y, 1992) |
| "The adrenergic alpha-1 and -2 adrenoceptors in six human hypertrophied prostatic adenomas were measured in the saturation experiment using 3H-prazosin and 3H-yohimbine." | 3.68 | [Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas]. ( Kondo, S; Morita, T, 1992) |
| " A dosage of 12 mg/day did not improve subjective symptoms more than did the 9 mg/day dose." | 2.66 | [Clinical study of bunazosin hydrochloride, an alpha 1-adrenergic blocker, in benign prostatic obstruction and neurogenic bladder dysfunction]. ( Kondo, A; Mitsuya, H; Otani, T; Takita, T, 1987) |
| " Bunazosin (10(-7) M) blocked norepinephrine-induced contraction with a parallel shift of the dose-response curve in both directions (pA2: 8." | 1.29 | Effect of bunazosin, alpha 1-adrenoceptor blocker, on multidirectional contractile response and localization of bunazosin binding sites in human hypertrophied prostate. ( Ishida, Y; Kawabe, K; Kurimoto, S; Moriyama, N; Nakamura, T; Orikasa, E, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oshika, T | 1 |
| Ohashi, Y | 1 |
| Inamura, M | 1 |
| Ohki, K | 1 |
| Okamoto, S | 1 |
| Koyama, T | 1 |
| Sakabe, I | 1 |
| Takahashi, K | 1 |
| Fujita, Y | 1 |
| Miyoshi, T | 1 |
| Yasuma, T | 1 |
| Moriyama, N | 1 |
| Orikasa, E | 1 |
| Nakamura, T | 1 |
| Kurimoto, S | 1 |
| Ishida, Y | 1 |
| Kawabe, K | 2 |
| Suzuki, H | 1 |
| Morita, T | 1 |
| Kondo, S | 1 |
| Fujita, T | 1 |
| Ohshima, S | 1 |
| Asano, H | 1 |
| Ono, Y | 1 |
| Kinukawa, T | 1 |
| Kato, N | 1 |
| Hirabayashi, S | 1 |
| Kumamoto, Y | 3 |
| Tsukamoto, T | 3 |
| Yachiku, S | 1 |
| Kaneko, S | 1 |
| Koyanagi, T | 1 |
| Togashi, M | 1 |
| Maru, A | 1 |
| Tsuchida, S | 2 |
| Nishizawa, O | 2 |
| Orikasa, S | 1 |
| Yamada, S | 1 |
| Suzuki, M | 1 |
| Matsuoka, Y | 1 |
| Kato, Y | 1 |
| Kimura, R | 1 |
| Maruyama, M | 1 |
| Kobayashi, S | 1 |
| Takita, T | 1 |
| Kondo, A | 1 |
| Mitsuya, H | 1 |
| Otani, T | 1 |
| Yokoyama, E | 2 |
| Koshiba, K | 1 |
| Ishibashi, A | 1 |
| Ogawa, A | 1 |
| Tomita, Y | 1 |
| Aso, Y | 1 |
| Takagi, Y | 1 |
| Furuya, S | 1 |
| Takatsuka, K | 1 |
| Tamiya, T | 1 |
| Miyamoto, S | 1 |
| Aoyama, T | 1 |
| Honma, A | 1 |
1 review available for bunazosin and Prostatic Hyperplasia
| Article | Year |
|---|---|
Treatment of benign prostatic hyperplasia and hypertension in elderly hypertensive patients.
Topics: Adrenergic alpha-Antagonists; Aged; Female; Humans; Hypertension; Male; Multicenter Studies as Topic | 1998 |
5 trials available for bunazosin and Prostatic Hyperplasia
| Article | Year |
|---|---|
[The evaluation of the effects of bunazosin hydrochloride in the treatment of prostatic hyperplasia].
Topics: Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Humans; Male; Middle Aged; Prostat | 1992 |
[A double-blind trial on the effect of bunazosin hydrochloride for the symptoms of benign prostatic hypertrophy].
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Alanine; Chi-Square Distribution; Double-Blin | 1990 |
[Clinical study of bunazosin hydrochloride, an alpha 1-adrenergic blocker, in benign prostatic obstruction and neurogenic bladder dysfunction].
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; | 1987 |
[A double-blind trial on the effect of alpha-adrenergic blocker (bunazosin hydrochloride) in the symptomatic treatment of prostatism].
Topics: Adrenergic alpha-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Mid | 1987 |
[Clinical efficacy of oxendolene (antiandrogen) and bunazosin hydrochloride (alpha-adrenergic blocker) in the treatment of prostatism--comparative study of oxendolone, bunazocin hydrochloride and their combination].
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Androgen Antagonists; Drug Evaluation; Drug T | 1987 |
6 other studies available for bunazosin and Prostatic Hyperplasia
| Article | Year |
|---|---|
Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha(1)-adrenoceptor antagonist.
Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Cata | 2007 |
Effect of bunazosin, alpha 1-adrenoceptor blocker, on multidirectional contractile response and localization of bunazosin binding sites in human hypertrophied prostate.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Auto | 1995 |
Bunazosin. Andante, Detantol, E 1015, E 643, EA 0643.
Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Area Under Curve; Clinical Trials as To | 1999 |
[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas].
Topics: Adenoma; Adrenergic alpha-Antagonists; Aged; Humans; Male; Piperazines; Prazosin; Prostatic Hyperpla | 1992 |
[3H]bunazosin, a novel selective radioligand of alpha 1 adrenoceptors in human prostates.
Topics: Adrenergic alpha-Antagonists; Cell Membrane; Humans; Male; Prazosin; Prostate; Prostatic Hyperplasia | 1991 |
[Characterization and localization of alpha 1-adrenoceptors in human prostate--with special reference to the zonal difference in receptor distribution].
Topics: Autoradiography; Binding Sites; Humans; Male; Prazosin; Prostate; Prostatic Hyperplasia; Quinazoline | 1991 |