Page last updated: 2024-10-23

bunazosin and Obesity

bunazosin has been researched along with Obesity in 5 studies

bunazosin: structure

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" We investigated the effect of a slow-release alpha1-receptor blocker, bunazosin hydrochloride, on leptin levels and insulin resistance in obese hypertensive patients with hyperleptinemia."9.12An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia. ( Ihara, S; Kawana, M; Sakai, R; Shimamoto, K; Watanabe, H, 2006)
"To investigate insulin insensitivity and its reversibility, we performed an insulin sensitivity test using the steady state plasma glucose (SSPG) method in 10 lean hypertensive subjects with normal glucose tolerance before and after treatment with alpha 1-blocker bunazosin, and 14 age body mass index-adjusted healthy control subjects."7.68Insulin insensitivity in nonobese, nondiabetic essential hypertension and its improvement by an alpha 1-blocker (bunazosin). ( Asakura, Y; Harano, Y; Hirose, J; Kageyama, A; Omae, T; Sato, A; Suzuki, M, 1992)
" We investigated the effect of a slow-release alpha1-receptor blocker, bunazosin hydrochloride, on leptin levels and insulin resistance in obese hypertensive patients with hyperleptinemia."5.12An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia. ( Ihara, S; Kawana, M; Sakai, R; Shimamoto, K; Watanabe, H, 2006)
"To investigate insulin insensitivity and its reversibility, we performed an insulin sensitivity test using the steady state plasma glucose (SSPG) method in 10 lean hypertensive subjects with normal glucose tolerance before and after treatment with alpha 1-blocker bunazosin, and 14 age body mass index-adjusted healthy control subjects."3.68Insulin insensitivity in nonobese, nondiabetic essential hypertension and its improvement by an alpha 1-blocker (bunazosin). ( Asakura, Y; Harano, Y; Hirose, J; Kageyama, A; Omae, T; Sato, A; Suzuki, M, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ihara, S1
Shimamoto, K1
Watanabe, H1
Sakai, R1
Kawana, M1
Bönner, G1
Schmieder, R1
Chrosch, R1
Weidinger, G1
Weichenhain, B1
Stemplinger, J1
Ziegler, AG1
Rabl, W1
Standl, E1
Stiegler, H1
Suzuki, M1
Hirose, J1
Asakura, Y1
Sato, A1
Kageyama, A1
Harano, Y1
Omae, T1
Kobatake, T1
Watanabe, Y1
Matsuzawa, Y1
Tokunaga, K1
Fujioka, S1
Kawamoto, T1
Keno, Y1
Tarui, S1
Yoshida, H1

Trials

2 trials available for bunazosin and Obesity

ArticleYear
An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure;

2006
Effect of bunazosin and atenolol on glucose metabolism in obese, nondiabetic patients with primary hypertension.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Blood

1997

Other Studies

3 other studies available for bunazosin and Obesity

ArticleYear
[Alström syndrome--a rare disease of diabetic association].
    Medizinische Klinik (Munich, Germany : 1983), 1997, Mar-15, Volume: 92, Issue:3

    Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diagnosis, Differential; DNA Mutational Analysi

1997
Insulin insensitivity in nonobese, nondiabetic essential hypertension and its improvement by an alpha 1-blocker (bunazosin).
    American journal of hypertension, 1992, Volume: 5, Issue:12 Pt 1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Apoproteins; Blood Glucose; Blood Pressure; Catecholamine

1992
Age-related changes in adrenergic alpha 1, alpha 2, and beta receptors of rat white fat cell membranes: an analysis using [3H]bunazosin as a novel ligand for the alpha 1 adrenoceptor.
    Journal of lipid research, 1991, Volume: 32, Issue:2

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Binding S

1991