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bunazosin and Myocardial Ischemia

bunazosin has been researched along with Myocardial Ischemia in 6 studies

bunazosin: structure

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Treatment with bunazosin ameliorated this ischemia-related shortening of refractory periods at both the endo- and epicardial sites, with a greater effect seen epicardially (p < 0."5.30Differences in refractory-period response of canine subendocardium and subepicardium to bunazosin, an alpha1-adrenoceptor antagonist, and propranolol during myocardial ischemia. ( Handa, S; Iwamoto, T; Kusuzaki, S; Takigawa, O; Tanabe, T; Usui, K; Yoshitake, M, 1997)
"Treatment with bunazosin ameliorated this ischemia-related shortening of refractory periods at both the endo- and epicardial sites, with a greater effect seen epicardially (p < 0."1.30Differences in refractory-period response of canine subendocardium and subepicardium to bunazosin, an alpha1-adrenoceptor antagonist, and propranolol during myocardial ischemia. ( Handa, S; Iwamoto, T; Kusuzaki, S; Takigawa, O; Tanabe, T; Usui, K; Yoshitake, M, 1997)
"Prazosin and yohimbine were found to produce a significant increase in plasma norepinephrine levels in contrast to bunazosin, which had no significant effect."1.29Effects of alpha-adrenergic blockade on regional myocardial function in canine ischemic myocardium during beta-adrenergic blockade. ( Kono, M; Morita, S; Rubsamen, R, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tanabe, T4
Takahashi, K2
Usui, K3
Kitada, M2
Mori, H3
Yoshioka, K1
Handa, S3
Kono, M1
Morita, S1
Rubsamen, R1
Nasa, Y1
Yabe, K1
Takeo, S1
Kusuzaki, S1
Yoshitake, M1
Takigawa, O1
Iwamoto, T1
Shinozaki, Y1

Other Studies

6 other studies available for bunazosin and Myocardial Ischemia

ArticleYear
Effects of bunazosin, a selective alpha 1-blocking agent, and propranolol used alone and in combination on canine ventricular refractoriness and its dispersion during myocardial ischemia.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Coronary Circulation; Dogs; Drug Therapy, Combination; Electr

1993
Effects of sympathetic stimulation, with and without previous alpha 1 and beta adrenoceptor blockade, on refractoriness dispersion in canine heart.
    Cardiovascular research, 1994, Volume: 28, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Electrophysiology; Heart; Myocardial Ischemia; Proprano

1994
Effects of alpha-adrenergic blockade on regional myocardial function in canine ischemic myocardium during beta-adrenergic blockade.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Coronary Circulation; Dogs; Fema

1995
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A

1997
Differences in refractory-period response of canine subendocardium and subepicardium to bunazosin, an alpha1-adrenoceptor antagonist, and propranolol during myocardial ischemia.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists;

1997
Disproportional response between refractory period and blood flow to alpha 1- and beta-adrenoceptor blockade in canine ischemic myocardium.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists;

1998