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bunazosin and Muscle Contraction

bunazosin has been researched along with Muscle Contraction in 9 studies

bunazosin: structure

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Bunazosin (10(-7) M) blocked norepinephrine-induced contraction with a parallel shift of the dose-response curve in both directions (pA2: 8."1.29Effect of bunazosin, alpha 1-adrenoceptor blocker, on multidirectional contractile response and localization of bunazosin binding sites in human hypertrophied prostate. ( Ishida, Y; Kawabe, K; Kurimoto, S; Moriyama, N; Nakamura, T; Orikasa, E, 1995)
"Moxisylyte has a relaxant action on the urethra that is probably ascribable to its alpha 1-adrenoceptor antagonist and Ca++ antagonist actions."1.28[Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder]. ( Hayashi, Y; Ikeda, K; Ohnishi, H; Watanabe, K, 1991)
"Bunazosin has an antagonistic action on this receptor."1.27Actions of the alpha-1 adrenoceptor blocker bunazosin on the norepinephrine-induced contraction of smooth muscles in the rabbit proximal urethra. ( Itoh, T; Kimoto, Y; Nozaki, M, 1987)
" The order of affinity (pA2) for presynaptic alpha-receptors, as assessed from parallel shift of the dose-response curve to clonidine, was: phentolamine greater than yohimbine greater than tolazoline greater than E-643 greater than or equal to prazosin."1.26Comparison of pre- and postsynaptic alpha-adrenoceptor blocking effects of E-643 in the isolated vas deferens of the rat. ( Shoji, T, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's5 (55.56)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoshi, K1
Fujino, S1
Shoji, T1
Vizi, ES1
Ludvig, N1
Moriyama, N1
Orikasa, E1
Nakamura, T1
Kurimoto, S1
Ishida, Y1
Kawabe, K1
Nasa, Y1
Ichihara, K1
Yoshida, R1
Abiko, Y1
Shinozuka, K1
Kobayashi, Y1
Shimoura, K1
Hattori, K1
Watanabe, K2
Hayashi, Y2
Ikeda, K2
Ohnishi, H2
Kimoto, Y1
Nozaki, M1
Itoh, T1

Other Studies

9 other studies available for bunazosin and Muscle Contraction

ArticleYear
Effects of alpha blockers on blood pressure and on the Ca-contracture of cat aortic strips.
    Japanese journal of pharmacology, 1980, Volume: 30, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Calcium; Cats; Female; In Vitro Techni

1980
Comparison of pre- and postsynaptic alpha-adrenoceptor blocking effects of E-643 in the isolated vas deferens of the rat.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniq

1981
(-)-Amidephrine, a selective agonist for alpha 1-adrenoceptors.
    European journal of pharmacology, 1983, Aug-05, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Electric Stimulation; Ethanolamines; In Vitro Techniques; Kineti

1983
Effect of bunazosin, alpha 1-adrenoceptor blocker, on multidirectional contractile response and localization of bunazosin binding sites in human hypertrophied prostate.
    General pharmacology, 1995, Volume: 26, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Auto

1995
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Role of nitric oxide from the endothelium on the neurogenic contractile responses of rabbit pulmonary artery.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; End

1992
[Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; I

1991
[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Femal

1991
Actions of the alpha-1 adrenoceptor blocker bunazosin on the norepinephrine-induced contraction of smooth muscles in the rabbit proximal urethra.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Calcium; Dose-Response Relationship, Drug; Gua

1987