bunazosin has been researched along with Intraocular Pressure in 20 studies
bunazosin: structure
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of bunazosin hydrochloride, a new highly selective alpha 1 adrenergic antagonist, on the intraocular pressure (IOP) and aqueous humor dynamics in healthy human volunteers were studied." | 9.07 | [The effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in human]. ( Kusunoki, T; Kuwayama, Y; Manabe, R; Shimizu, Y; Sun, N; Takagi, T; Tanaka, M; Yamamoto, R, 1991) |
| "We investigated the effects of topical administration of bunazosin hydrochloride, a new selective alpha 1-adrenergic antagonist, on intraocular pressure and aqueous humor dynamics in normal human eyes." | 9.07 | Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes. ( Araie, M; Azuma, I; Nakajima, M; Oshika, T; Sugiyama, T, 1991) |
| "To determine whether there is alpha 1-adrenergic receptor heterogeneity associated with the regulation of intraocular pressure (IOP) and mydriasis in rabbits, the authors tested the hypothesis by characterizing the ability of the selective alpha 1-adrenergic antagonist, bunazosin, to block the ocular hypertensive and mydriatic responses to alpha 1-adrenoceptor stimulation by either norepinephrine (NE) or phenylephrine (PE)." | 7.68 | Selective suppression by bunazosin of alpha-adrenergic agonist evoked elevation of intraocular pressure in sympathectomized rabbit eyes. ( Kuwayama, Y; Matsugi, T; Nishimura, K; Shirasawa, E; Sun, N, 1993) |
| "The effects of topically applied bunazosin hydrochloride, a selective alpha 1 blocker under development as a drug to treat glaucoma, were studied in regard to the choroidal capillary blood flow, intraocular pressure (IOP), and blood pressure in albino rabbit eyes in comparison with propranolol hydrochloride, a non-selective beta blocker." | 7.68 | [Effects of topically applied bunazosin hydrochloride on choroidal capillary blood flow and intraocular pressure of rabbit eye]. ( Sugiyama, T, 1991) |
| "The effects of topically applied bunazosin hydrochloride, a recently developed highly selective alpha 1-adrenergic antagonist, on intraocular pressure, pupillary diameter, aqueous protein concentration, anterior chamber volume, aqueous flow rate and tonographic outflow facility were investigated in eight normal human volunteers." | 7.68 | [Changes in intraocular pressure and aqueous humor dynamics of normal human eyes after topical application of bunazosin hydrochloride]. ( Araie, M; Oshika, T, 1990) |
| "01% may provide an additional intraocular pressure reduction in patients already receiving latanoprost or timolol." | 5.11 | Efficacy of bunazosin hydrochloride 0.01% as adjunctive therapy of latanoprost or timolol. ( Kobayashi, H; Kobayashi, K; Okinami, S, 2004) |
| "The effects of bunazosin hydrochloride, a new highly selective alpha 1 adrenergic antagonist, on the intraocular pressure (IOP) and aqueous humor dynamics in healthy human volunteers were studied." | 5.07 | [The effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in human]. ( Kusunoki, T; Kuwayama, Y; Manabe, R; Shimizu, Y; Sun, N; Takagi, T; Tanaka, M; Yamamoto, R, 1991) |
| "We investigated the effects of topical administration of bunazosin hydrochloride, a new selective alpha 1-adrenergic antagonist, on intraocular pressure and aqueous humor dynamics in normal human eyes." | 5.07 | Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes. ( Araie, M; Azuma, I; Nakajima, M; Oshika, T; Sugiyama, T, 1991) |
| "We have constructed a new ocular pharmacokinetic pharmacodynamic (PK/PD) model for anti-glaucoma drugs to describe ocular hypotensive effects on intraocular pressure (IOP) after instillation of a combination of an alpha(1)-adrenergic antagonist, bunazosin, and a beta-adrenergic antagonist, timolol, into rabbits." | 3.74 | Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs. ( Higuchi, S; Kawazu, K; Kitahara, T; Nakamura, J; Nakashima, M; Nishida, K; Sakanaka, K; Sasaki, H; Tomonari, M, 2008) |
| "To determine whether there is alpha 1-adrenergic receptor heterogeneity associated with the regulation of intraocular pressure (IOP) and mydriasis in rabbits, the authors tested the hypothesis by characterizing the ability of the selective alpha 1-adrenergic antagonist, bunazosin, to block the ocular hypertensive and mydriatic responses to alpha 1-adrenoceptor stimulation by either norepinephrine (NE) or phenylephrine (PE)." | 3.68 | Selective suppression by bunazosin of alpha-adrenergic agonist evoked elevation of intraocular pressure in sympathectomized rabbit eyes. ( Kuwayama, Y; Matsugi, T; Nishimura, K; Shirasawa, E; Sun, N, 1993) |
| "The effects of topically applied bunazosin hydrochloride, a selective alpha 1 blocker under development as a drug to treat glaucoma, were studied in regard to the choroidal capillary blood flow, intraocular pressure (IOP), and blood pressure in albino rabbit eyes in comparison with propranolol hydrochloride, a non-selective beta blocker." | 3.68 | [Effects of topically applied bunazosin hydrochloride on choroidal capillary blood flow and intraocular pressure of rabbit eye]. ( Sugiyama, T, 1991) |
| "Effects of topically applied bunazosin, an alpha 1-adrenoceptor blocker, on intraocular pressure (IOP) and pupillary diameter were investigated in normotensive rabbits and cats, in addition to experimentally hypertensive rabbits." | 3.68 | [Ocular hypotensive effects of topically applied bunazosin, an alpha 1-adrenoceptor blocker, in rabbits and cats]. ( Hikida, M; Kinoshita, M; Kuwayama, Y; Nishimura, K; Shirasawa, E, 1991) |
| "The effects of topically applied bunazosin hydrochloride, a recently developed highly selective alpha 1-adrenergic antagonist, on intraocular pressure, pupillary diameter, aqueous protein concentration, anterior chamber volume, aqueous flow rate and tonographic outflow facility were investigated in eight normal human volunteers." | 3.68 | [Changes in intraocular pressure and aqueous humor dynamics of normal human eyes after topical application of bunazosin hydrochloride]. ( Araie, M; Oshika, T, 1990) |
| "In an attempt to study the effect of change in the intraocular pressure (IOP) on the status of the vitreous-aqueous interface, the effect of topical bunazosin was studied in the rabbit eye using the new Johnson-Maurice method." | 3.67 | Effects of intraocular pressure change on movement of FITC-dextran across vitreous-aqueous interface. ( Araie, M; Sugiura, Y, 1989) |
| "Historically, treatment for glaucoma has been based on lowering intraocular pressure." | 2.38 | [Progress in medical treatment for glaucoma]. ( Azuma, I, 1993) |
| "To report a case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy." | 1.34 | [Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy]. ( Higashide, T; Sugiyama, K; Wakabayashi, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 11 (55.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakanaka, K | 2 |
| Kawazu, K | 2 |
| Tomonari, M | 2 |
| Kitahara, T | 2 |
| Nakashima, M | 2 |
| Nishida, K | 2 |
| Nakamura, J | 2 |
| Sasaki, H | 2 |
| Higuchi, S | 1 |
| Akaishi, T | 2 |
| Shimazaki, A | 1 |
| Matsugi, T | 3 |
| Miyawaki, N | 1 |
| Hara, H | 2 |
| Kuwayama, Y | 4 |
| Kobayashi, H | 1 |
| Kobayashi, K | 1 |
| Okinami, S | 1 |
| Kawakami, S | 1 |
| Takagi, Y | 1 |
| Ishida, N | 1 |
| Kashiwagi, K | 1 |
| Goto, W | 1 |
| Oku, H | 1 |
| Okuno, T | 1 |
| Sugiyama, T | 3 |
| Ikeda, T | 1 |
| Wakabayashi, T | 1 |
| Higashide, T | 1 |
| Sugiyama, K | 1 |
| Azuma, I | 2 |
| Aihara, M | 1 |
| Araie, M | 6 |
| Kaburaki, T | 1 |
| Shirato, S | 1 |
| Nishimura, K | 2 |
| Sun, N | 2 |
| Shirasawa, E | 2 |
| Tamaki, Y | 1 |
| Tomita, K | 1 |
| Tomidokoro, A | 1 |
| Nagahara, M | 1 |
| Zhan, GL | 1 |
| Toris, CB | 1 |
| Camras, CB | 1 |
| Wang, YL | 1 |
| Yablonski, ME | 1 |
| Trew, DR | 1 |
| Wright, LA | 1 |
| Smith, SE | 1 |
| Takagi, T | 1 |
| Yamamoto, R | 1 |
| Tanaka, M | 1 |
| Kusunoki, T | 1 |
| Shimizu, Y | 1 |
| Manabe, R | 1 |
| Kinoshita, M | 1 |
| Hikida, M | 1 |
| Oshika, T | 2 |
| Nakajima, M | 1 |
| Sugiura, Y | 2 |
1 review available for bunazosin and Intraocular Pressure
| Article | Year |
|---|---|
[Progress in medical treatment for glaucoma].
Topics: Adrenergic alpha-Antagonists; Choroid; Dinoprost; Endothelins; Glaucoma; Humans; Intraocular Pressur | 1993 |
5 trials available for bunazosin and Intraocular Pressure
| Article | Year |
|---|---|
Efficacy of bunazosin hydrochloride 0.01% as adjunctive therapy of latanoprost or timolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Drug Administration Schedule; Drug | 2004 |
Effects of topical adrenergic agents on tissue circulation in rabbit and human optic nerve head evaluated with laser speckle tissue circulation analyzer.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Animals; | 1997 |
Ocular responses in healthy subjects to topical bunazosin 0.3%--an alpha 1-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Adult; Double-Blind Method; Eye; Eyelids; Female; Humans; Intraocular | 1991 |
[The effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in human].
Topics: Adrenergic alpha-Antagonists; Adult; Aqueous Humor; Female; Humans; Intraocular Pressure; Male; Quin | 1991 |
Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adult; Aqueous Humor; Capillary Permeability; | 1991 |
14 other studies available for bunazosin and Intraocular Pressure
| Article | Year |
|---|---|
Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Algorithms; Animals; Aqueous Humor; Drug | 2008 |
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry].
Topics: Animals; Circadian Rhythm; Intraocular Pressure; Male; Quinazolines; Rabbits; Sulfonamides; Telemetr | 2003 |
Ocular pharmacokinetic/ pharmacodynamic modeling for bunazosin after instillation into rabbits.
Topics: Adrenergic alpha-Antagonists; Algorithms; Animals; Aqueous Humor; Eye; Injections; Intraocular Press | 2004 |
Effects of bunazosin hydrochloride on ciliary muscle constriction and matrix metalloproteinase activities.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Cattle; Cells, Cultur | 2004 |
Amelioration of endothelin-1-induced optic nerve head ischemia by topical bunazosin.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Endothelin-1; Evoked | 2005 |
[Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy].
Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Argon; Glaucoma, Open-Angle; Humans; I | 2007 |
[Effects of long-term application of bunazosin hydrochloride eye drops on the aqueous flow rate and blood-aqueous barrier permiability in rabbit eyes].
Topics: Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Blood; Intraocular Pressure; Ophthalmic Soluti | 1994 |
Selective suppression by bunazosin of alpha-adrenergic agonist evoked elevation of intraocular pressure in sympathectomized rabbit eyes.
Topics: Adrenergic alpha-Antagonists; Animals; Ganglia, Sympathetic; Ganglionectomy; Intraocular Pressure; M | 1993 |
Bunazosin reduces intraocular pressure in rabbits by increasing uveoscleral outflow.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aqueous Humor; | 1998 |
[Effects of topically applied bunazosin hydrochloride on choroidal capillary blood flow and intraocular pressure of rabbit eye].
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Capillaries; Choroid; Intraocular Pr | 1991 |
[Ocular hypotensive effects of topically applied bunazosin, an alpha 1-adrenoceptor blocker, in rabbits and cats].
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Cats; Intraocular Pressure; Male; Qu | 1991 |
[Changes in intraocular pressure and aqueous humor dynamics of normal human eyes after topical application of bunazosin hydrochloride].
Topics: Adrenergic alpha-Antagonists; Adult; Aqueous Humor; Depression, Chemical; Eye Proteins; Humans; Intr | 1990 |
Effects of intraocular pressure change on movement of FITC-dextran across vitreous-aqueous interface.
Topics: Adrenergic alpha-Antagonists; Animals; Anterior Chamber; Aqueous Humor; Dextrans; Female; Fluorescei | 1989 |
[The effect of bunazosin hydrochloride on the intraocular pressure and the aqueous humor dynamics of the rabbit eye].
Topics: Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Female; Intraocular Pressure; Quinazolines; Ra | 1988 |