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bunazosin and Heart Failure

bunazosin has been researched along with Heart Failure in 11 studies

bunazosin: structure

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
" Hemodynamic responses to Bunazosin (BZN) in congestive heart failure (CHF) were evaluated for 6 hours (hr) in 30 patients (A, normal cardiac function; B, mild cardiac dysfunction; C, severe cardiac dysfunction)."7.68Acute hemodynamic effects of bunazosin in congestive heart failure--differing responses according to degree of cardiac dysfunction. ( Kato, M; Kinugawa, T; Kitamura, H; Kotake, H; Mashiba, H; Matsumoto, T; Miyakoda, H; Noguchi, N; Ogino, K; Osaki, S, 1993)
"The purpose of this study was to investigate the therapeutic effect of an alpha 1-blocker, bunazosin, using an experimental murine model of congestive heart failure induced by viral myocarditis."7.68The effect of alpha 1-blocker, bunazosin on a murine model of congestive heart failure induced by viral myocarditis. ( Kawai, C; Matsumori, A; Okada, I; Tominaga, M; Yamada, T, 1992)
"To study the effect of bunazosin on exercise capacity in patients with congestive heart failure (NYHA II-III), anaerobic thresholds (AT, VO2, ml/min/kg) were measured before (control) and after initial 1 = 2mg administration of bunazosin (acute phase; N = 14) and after two weeks of bunazosin therapy (3mg/day, 1mg t."7.68[The acute and chronic effects of bunazosin on exercise capacity estimated by the anaerobic threshold in patients with chronic congestive heart failure]. ( Hosoda, S; Kaneko, N; Kawagoe, Y; Kimata, S; Kimura, H; Konno, K; Miki, N; Nagashima, H; Sumiyoshi, T, 1992)
"The acute hemodynamic effect (right atrial pressure, mean pulmonary artery pressure, pulmonary capillary wedge pressure, cardiac index, heart rate, blood pressure) and neurohumoral response (alpha-ANP, plasma renin activity, aldosterone, angiotensin II) of Bunazosin, oral alpha 1 blocker, was investigated in 28 patients with congestive heart failure at rest and immediately after exercise."7.67[Acute and chronic effects of bunazosin in patients with congestive heart failure]. ( Hasegawa, K; Inoue, S; Kawahara, Y; Nezuo, S; Sawayama, T; Tadaoka, S, 1989)
"The hemodynamic parameters (right atrial pressure, mean pulmonary artery pressure, pulmonary capillary wedge pressure, cardiac index, heart rate, blood pressure) and neurohumoral responses (alpha-ANP, plasma renin activity, aldosterone, angiotensin II) of Captopril, oral ACE inhibitor, and Bunazosin, oral alpha 1-blocker, were investigated in 28 patients with congestive heart failure at rest and after exercise."7.67[The effect of bunazosin vs captopril on hemodynamic and neurohumoral parameters in patients with congestive heart failure]. ( Hasegawa, K; Inoue, S; Kakumae, S; Kawahara, Y; Nakamura, T; Nakao, M; Nezuo, S; Sawayama, T; Tadaoka, S, 1989)
" Hemodynamic responses to Bunazosin (BZN) in congestive heart failure (CHF) were evaluated for 6 hours (hr) in 30 patients (A, normal cardiac function; B, mild cardiac dysfunction; C, severe cardiac dysfunction)."3.68Acute hemodynamic effects of bunazosin in congestive heart failure--differing responses according to degree of cardiac dysfunction. ( Kato, M; Kinugawa, T; Kitamura, H; Kotake, H; Mashiba, H; Matsumoto, T; Miyakoda, H; Noguchi, N; Ogino, K; Osaki, S, 1993)
"The purpose of this study was to investigate the therapeutic effect of an alpha 1-blocker, bunazosin, using an experimental murine model of congestive heart failure induced by viral myocarditis."3.68The effect of alpha 1-blocker, bunazosin on a murine model of congestive heart failure induced by viral myocarditis. ( Kawai, C; Matsumori, A; Okada, I; Tominaga, M; Yamada, T, 1992)
"To study the effect of bunazosin on exercise capacity in patients with congestive heart failure (NYHA II-III), anaerobic thresholds (AT, VO2, ml/min/kg) were measured before (control) and after initial 1 = 2mg administration of bunazosin (acute phase; N = 14) and after two weeks of bunazosin therapy (3mg/day, 1mg t."3.68[The acute and chronic effects of bunazosin on exercise capacity estimated by the anaerobic threshold in patients with chronic congestive heart failure]. ( Hosoda, S; Kaneko, N; Kawagoe, Y; Kimata, S; Kimura, H; Konno, K; Miki, N; Nagashima, H; Sumiyoshi, T, 1992)
"The acute hemodynamic effect (right atrial pressure, mean pulmonary artery pressure, pulmonary capillary wedge pressure, cardiac index, heart rate, blood pressure) and neurohumoral response (alpha-ANP, plasma renin activity, aldosterone, angiotensin II) of Bunazosin, oral alpha 1 blocker, was investigated in 28 patients with congestive heart failure at rest and immediately after exercise."3.67[Acute and chronic effects of bunazosin in patients with congestive heart failure]. ( Hasegawa, K; Inoue, S; Kawahara, Y; Nezuo, S; Sawayama, T; Tadaoka, S, 1989)
"The hemodynamic parameters (right atrial pressure, mean pulmonary artery pressure, pulmonary capillary wedge pressure, cardiac index, heart rate, blood pressure) and neurohumoral responses (alpha-ANP, plasma renin activity, aldosterone, angiotensin II) of Captopril, oral ACE inhibitor, and Bunazosin, oral alpha 1-blocker, were investigated in 28 patients with congestive heart failure at rest and after exercise."3.67[The effect of bunazosin vs captopril on hemodynamic and neurohumoral parameters in patients with congestive heart failure]. ( Hasegawa, K; Inoue, S; Kakumae, S; Kawahara, Y; Nakamura, T; Nakao, M; Nezuo, S; Sawayama, T; Tadaoka, S, 1989)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tamagawa, K1
Saito, T1
Oikawa, Y1
Maehara, K1
Yaoita, H1
Maruyama, Y1
Itoh, K1
Kohya, T1
Nishijima, H1
Yasuda, H1
Minami, S1
Tsujinaga, H1
Morimoto, Y2
Noda, E1
Yamamori, M1
Nakai, K1
Konishi, T2
Kawanami, C1
Hamada, M1
Nakano, T2
Takezawa, H2
Ogino, K1
Noguchi, N1
Osaki, S1
Kitamura, H1
Matsumoto, T1
Kato, M1
Kinugawa, T1
Miyakoda, H1
Kotake, H1
Mashiba, H1
Takahashi, M1
Shichiri, G1
Amano, M1
Kanamori, T1
Kinoshita, M1
Yamada, T1
Matsumori, A1
Okada, I1
Tominaga, M1
Kawai, C1
Kawagoe, Y1
Kimura, H1
Kaneko, N1
Sumiyoshi, T1
Nagashima, H1
Kimata, S1
Hosoda, S1
Konno, K1
Miki, N1
Kawahara, Y2
Hasegawa, K2
Sawayama, T2
Nezuo, S2
Inoue, S2
Tadaoka, S2
Okazaki, Y1
Mishima, M1
Hirayama, A1
Komamura, K1
Asada, S1
Ohara, T1
Lee, JM1
Matsumura, Y1
Yamamoto, K1
Nishida, K1
Nakamura, T1
Kakumae, S1
Nakao, M1
Kakuta, Y1
Makino, K1
Umino, M1
Nagano, K1
Koyama, T1
Kodera, T1

Other Studies

11 other studies available for bunazosin and Heart Failure

ArticleYear
Alterations of alpha-adrenergic modulations of coronary microvascular tone in dogs with heart failure.
    Journal of cardiac failure, 2005, Volume: 11, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood

2005
[Acute effect of a new alpha 1-receptor blocking drug, E-643, on severe congestive heart failure--pharmacokinetic and hemodynamic studies].
    Kokyu to junkan. Respiration & circulation, 1983, Volume: 31, Issue:10

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Drug Evaluation; Female; Heart Failure; Hemod

1983
[Acute effects of a new antihypertensive quinazoline derivative, E-643 in severe heart failure--hemodynamics, plasma catecholamine levels and blood gas data (author's transl)].
    Kokyu to junkan. Respiration & circulation, 1981, Volume: 29, Issue:7

    Topics: Adult; Aged; Catecholamines; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Quinazo

1981
Acute hemodynamic effects of bunazosin in congestive heart failure--differing responses according to degree of cardiac dysfunction.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Female; Heart; Heart Failure; Heart Rate;

1993
Increased uncoupling of beta-, beta 1- and beta 2-adrenoceptor to myocardial contraction in failing human myocardium.
    Japanese circulation journal, 1992, Volume: 56, Issue:7

    Topics: Adult; Aged; Binding, Competitive; Dobutamine; Down-Regulation; Female; Heart Failure; Humans; Iodoc

1992
The effect of alpha 1-blocker, bunazosin on a murine model of congestive heart failure induced by viral myocarditis.
    Japanese circulation journal, 1992, Volume: 56, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Encephalomyocarditis virus; Enterovir

1992
[The acute and chronic effects of bunazosin on exercise capacity estimated by the anaerobic threshold in patients with chronic congestive heart failure].
    Kokyu to junkan. Respiration & circulation, 1992, Volume: 40, Issue:11

    Topics: Adult; Aged; Anaerobic Threshold; Chronic Disease; Exercise Test; Exercise Tolerance; Female; Heart

1992
[Acute and chronic effects of bunazosin in patients with congestive heart failure].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:5

    Topics: Adrenergic alpha-Antagonists; Atrial Natriuretic Factor; Chronic Disease; Exercise Test; Female; Hea

1989
[Acute effects of oral bunazosin-hydrochloride in acute heart failure].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:11

    Topics: Acute Disease; Administration, Oral; Adrenergic alpha-Antagonists; Aged; Female; Heart Failure; Hemo

1989
[The effect of bunazosin vs captopril on hemodynamic and neurohumoral parameters in patients with congestive heart failure].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:12

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors;

1989
[Effects of oral bunazosin hydrochloride on hemodynamic and metabolic responses to exercise (ergometer, 25W, 5 min) in patients with severe congestive heart failure].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:2

    Topics: Aged; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Male; Metabolism; Middle Aged; Qui

1987