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bunazosin and Cardiac Hypertrophy

bunazosin has been researched along with Cardiac Hypertrophy in 3 studies

bunazosin: structure

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"To assess the protective effect of an alpha 1-blocker on the development of cardiac hypertrophy, the selective alpha 1-receptor antagonist bunazosin (2 mg/kg/d, by oral gavage and in drinking water) was given to male Dahl salt-sensitive rats fed a 4% NaCl diet for 7 weeks."7.69Prevention of cardiac hypertrophy by a sub-antihypertensive dose of the alpha 1-adrenergic antagonist bunazosin in Dahl salt-sensitive rats. ( Fukuda, N; Izumi, Y; Kanmatsuse, K; Kubo, A; Matsuoka, M; Nakayama, T; Soma, M; Watanabe, Y, 1996)
"To assess the protective effect of an alpha 1-blocker on the development of cardiac hypertrophy, the selective alpha 1-receptor antagonist bunazosin (2 mg/kg/d, by oral gavage and in drinking water) was given to male Dahl salt-sensitive rats fed a 4% NaCl diet for 7 weeks."3.69Prevention of cardiac hypertrophy by a sub-antihypertensive dose of the alpha 1-adrenergic antagonist bunazosin in Dahl salt-sensitive rats. ( Fukuda, N; Izumi, Y; Kanmatsuse, K; Kubo, A; Matsuoka, M; Nakayama, T; Soma, M; Watanabe, Y, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Izumi, Y1
Matsuoka, M1
Kubo, A1
Nakayama, T1
Fukuda, N1
Watanabe, Y2
Soma, M1
Kanmatsuse, K1
Kagiya, T1
Hori, M1
Iwakura, K1
Iwai, K1
Uchida, S1
Yoshida, H1
Kitabatake, A1
Inoue, M1
Kamada, T1
Tanaka, H1
Obata, H1
Haneda, T1

Other Studies

3 other studies available for bunazosin and Cardiac Hypertrophy

ArticleYear
Prevention of cardiac hypertrophy by a sub-antihypertensive dose of the alpha 1-adrenergic antagonist bunazosin in Dahl salt-sensitive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardiomegaly; Hypertension; Male; Quinazoline

1996
Role of increased alpha 1-adrenergic activity in cardiomyopathic Syrian hamster.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 2

    Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channels; Cardiomegaly; Cardiomyopathies; Cricetinae;

1991
Effects of regression of left ventricular hypertrophy following atenolol or bunazosin therapy on ischemic cardiac function and myocardial metabolism in spontaneously hypertensive rats.
    Japanese circulation journal, 1991, Volume: 55, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atenolol; Blood Pre

1991