bumetanide has been researched along with Tuberous Sclerosis in 1 studies
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bumetanide treatment is a potential treatment to alleviate the behavioral burden and quality of life associated with TSC." | 6.94 | Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study. ( Bruining, H; Jansen, FE; Oranje, B; Scheepers, FE; Sprengers, JJ; van Andel, DM, 2020) |
| "Bumetanide treatment is a potential treatment to alleviate the behavioral burden and quality of life associated with TSC." | 2.94 | Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study. ( Bruining, H; Jansen, FE; Oranje, B; Scheepers, FE; Sprengers, JJ; van Andel, DM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Andel, DM | 1 |
| Sprengers, JJ | 1 |
| Oranje, B | 1 |
| Scheepers, FE | 1 |
| Jansen, FE | 1 |
| Bruining, H | 1 |
1 trial available for bumetanide and Tuberous Sclerosis
| Article | Year |
|---|---|
Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study.
Topics: Adolescent; Autism Spectrum Disorder; Bumetanide; Child; Disease Susceptibility; Duration of Therapy | 2020 |