Page last updated: 2024-10-23

bumetanide and Spinal Cord Injuries

bumetanide has been researched along with Spinal Cord Injuries in 6 studies

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Bumetanide treatment significantly reduced average pain intensity according to the NRS and the short form of the McGill Pain Questionnaire scores."2.94Preliminary study of analgesic effect of bumetanide on neuropathic pain in patients with spinal cord injury. ( Behzad, E; Gharaylou, Z; Hadjighassem, M; Hosseindoost, S; Majedi, H; Nasirinezhad, F; Ramezani, F; Shafaghi, L; Zarepour, L, 2020)
"Current anti-spastic medication significantly compromises motor recovery after spinal cord injury (SCI), indicating a critical need for alternative interventions."1.91Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training. ( Bilchak, J; Caron, G; Côté, MP, 2023)
"Sprague Dawley rats received a spinal cord transection at T12 and were assigned to SCI-7d, SCI-14d, SCI-14d+exercise, SCI-28d, SCI-28d+exercise, or SCI-56d groups."1.40Exercise modulates chloride homeostasis after spinal cord injury. ( Côté, MP; Gandhi, S; Houlé, JD; Zambrotta, M, 2014)
"Neuropathic pain is a common problem following spinal cord injury (SCI)."1.36Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury. ( Ahmed, MM; Hasbargen, T; Kahle, KT; Li, L; Miranpuri, G; Resnick, D; Sun, D, 2010)
"The rats developed hyperalgesia between days 21 and 42 post-SCI."1.35The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury. ( Allcock, B; Baggott, C; Cain, J; Cramer, SW; Miranpuri, G; Rajpal, S; Resnick, D; Sun, D; Tilghman, J, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Caron, G1
Bilchak, J1
Côté, MP2
Zarepour, L1
Gharaylou, Z1
Hadjighassem, M1
Shafaghi, L1
Majedi, H1
Behzad, E1
Hosseindoost, S1
Ramezani, F1
Nasirinezhad, F1
Gandhi, S1
Zambrotta, M1
Houlé, JD1
Huang, YJ1
Lee, KH1
Murphy, L1
Garraway, SM1
Grau, JW1
Cramer, SW1
Baggott, C1
Cain, J1
Tilghman, J1
Allcock, B1
Miranpuri, G2
Rajpal, S1
Sun, D2
Resnick, D2
Hasbargen, T1
Ahmed, MM1
Li, L1
Kahle, KT1

Trials

1 trial available for bumetanide and Spinal Cord Injuries

ArticleYear
Preliminary study of analgesic effect of bumetanide on neuropathic pain in patients with spinal cord injury.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 81

    Topics: Adult; Bumetanide; Female; Humans; Male; Neuralgia; Pilot Projects; Quality of Life; Solute Carrier

2020

Other Studies

5 other studies available for bumetanide and Spinal Cord Injuries

ArticleYear
Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training.
    The Journal of physiology, 2023, Volume: 601, Issue:8

    Topics: Animals; Bumetanide; Chlorides; Motor Neurons; Muscle Spasticity; Rats; Spinal Cord; Spinal Cord Inj

2023
Exercise modulates chloride homeostasis after spinal cord injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jul-02, Volume: 34, Issue:27

    Topics: Acetates; Animals; Brain-Derived Neurotrophic Factor; Bumetanide; Chloride Channels; Chlorides; Cord

2014
Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization.
    Experimental neurology, 2016, Volume: 285, Issue:Pt A

    Topics: Acetates; Analysis of Variance; Animals; Bicuculline; Bumetanide; Capsaicin; Disease Models, Animal;

2016
The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury.
    Molecular pain, 2008, Sep-17, Volume: 4

    Topics: Animals; Bumetanide; Hyperalgesia; K Cl- Cotransporters; Male; Pain; Rats; Rats, Sprague-Dawley; Sod

2008
Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury.
    Annals of the New York Academy of Sciences, 2010, Volume: 1198

    Topics: Animals; Bumetanide; Chronic Disease; gamma-Aminobutyric Acid; Hyperalgesia; Inflammation; K Cl- Cot

2010