Page last updated: 2024-10-23

bumetanide and Pregnancy

bumetanide has been researched along with Pregnancy in 23 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Bumetanide was suggested as an adjunct to phenobarbital for suppression of neonatal seizures."8.02A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia. ( Gailus, B; Gericke, B; Johne, M; Käufer, C; Löscher, W; Römermann, K, 2021)
"We report that the oxytocin-mediated neuroprotective γ-aminobutyric acid (GABA) excitatory-inhibitory shift during delivery is abolished in the valproate and fragile X rodent models of autism."7.80Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. ( Ben-Ari, Y; Brouchoud, C; Burnashev, N; Chazal, G; Eftekhari, S; Ferrari, DC; Khalilov, I; Lemonnier, E; Lozovaya, N; Nardou, R; Shahrokhi, A; Tsintsadze, T; Tsintsadze, V; Tyzio, R, 2014)
"Bumetanide was suggested as an adjunct to phenobarbital for suppression of neonatal seizures."4.02A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia. ( Gailus, B; Gericke, B; Johne, M; Käufer, C; Löscher, W; Römermann, K, 2021)
"We report that the oxytocin-mediated neuroprotective γ-aminobutyric acid (GABA) excitatory-inhibitory shift during delivery is abolished in the valproate and fragile X rodent models of autism."3.80Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. ( Ben-Ari, Y; Brouchoud, C; Burnashev, N; Chazal, G; Eftekhari, S; Ferrari, DC; Khalilov, I; Lemonnier, E; Lozovaya, N; Nardou, R; Shahrokhi, A; Tsintsadze, T; Tsintsadze, V; Tyzio, R, 2014)
"The corticosterone level was significantly increased immediately after repeated neonatal sevoflurane exposures."1.43Heightened stress response and cognitive impairment after repeated neonatal sevoflurane exposures might be linked to excessive GABAAR-mediated depolarization. ( Li, F; Liu, G; Qian, B; Qian, W; Zhang, A; Zhu, T, 2016)
"Gadolinium is a rare-earth lanthanide metal ion and is used as organic gadolinium complexes in magnetic resonance imaging (MRI)."1.35Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons. ( Hirao, K; Ishibashi, H; Nabekura, J; Yamaguchi, J, 2009)
"The Kmf of 36Cl- was not inhibited by anoxia and had a low temperature quotient (Q10 between 32 and 37 degrees C was 1."1.29Transfer of Cl- across placenta of anesthetized rat. ( Husain, S; Sibley, CP; Stulc, J; Stulcová, B, 1996)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's9 (39.13)18.2507
2000's7 (30.43)29.6817
2010's5 (21.74)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Skorput, AG1
Lee, SM1
Yeh, PW1
Yeh, HH1
Johne, M1
Käufer, C1
Römermann, K1
Gailus, B1
Gericke, B1
Löscher, W1
Cloarec, R1
Riffault, B1
Dufour, A1
Rabiei, H1
Gouty-Colomer, LA1
Dumon, C1
Guimond, D1
Bonifazi, P1
Eftekhari, S2
Lozovaya, N2
Ferrari, DC2
Ben-Ari, Y2
Tyzio, R1
Nardou, R1
Tsintsadze, T1
Shahrokhi, A1
Khalilov, I1
Tsintsadze, V1
Brouchoud, C1
Chazal, G1
Lemonnier, E1
Burnashev, N1
Liu, G1
Zhu, T1
Zhang, A1
Li, F1
Qian, W1
Qian, B1
Ishibashi, H1
Hirao, K1
Yamaguchi, J1
Nabekura, J1
Reid, AY1
Riazi, K1
Campbell Teskey, G1
Pittman, QJ1
Titz, S1
Hormuzdi, S1
Lewen, A1
Monyer, H1
Misgeld, U1
Dayioglu, E1
Buharalioglu, CK1
Saracoglu, F1
Akar, F1
Delpy, A1
Allain, AE1
Meyrand, P1
Branchereau, P1
Faller, DP2
Egan, DA1
Ryan, MP2
Johanson, CE1
Preston, JE1
O'Reilly, CM1
Souza, P1
O'Brodovich, H2
Post, M2
Stulc, J1
Stulcová, B1
Husain, S1
Sibley, CP1
Zhou, L1
Graeff, RW1
McCray, PB1
Simonet, WS1
Whitsett, JA1
Marunaka, Y1
Niisato, N1
Tanswell, AK1
Davis, JP1
Chien, PF1
Chipperfield, AR1
Gordon, A1
Harper, AA1
Gibson, JS1
Speake, PF1
Muzyamba, MC1
Husain, F1
Luckas, MC1
Ellory, JC1
Haines, PG1
Jarvis, HG1
King, S1
Noormohamed, FH1
Chetty, MC1
Fisher, J1
Hill, P1
Nicolaou, A1
Stewart, GW1
Carlton, DP1
Cummings, JJ1
Chapman, DL1
Poulain, FR1
Bland, RD1
Thom, J1
Perks, AM1
Andersen, JR1
Borggaard, B1
Olsen, EB1
Stimpel, H1
Nyholm, HC1
Schroeder, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures[NCT04368936]121 participants (Actual)Observational [Patient Registry]2015-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for bumetanide and Pregnancy

ArticleYear
Two further British families with the 'cryohydrocytosis' form of hereditary stomatocytosis.
    British journal of haematology, 2001, Volume: 113, Issue:4

    Topics: Anemia, Hemolytic, Congenital Nonspherocytic; Bumetanide; Cold Temperature; England; Erythrocytes; F

2001

Other Studies

22 other studies available for bumetanide and Pregnancy

ArticleYear
The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero.
    eLife, 2019, 09-23, Volume: 8

    Topics: Alcohol Drinking; Animals; Bumetanide; Cerebral Cortex; Disease Models, Animal; Female; Fetal Alcoho

2019
A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia.
    Epilepsia, 2021, Volume: 62, Issue:6

    Topics: Animals; Animals, Newborn; Anticonvulsants; Asphyxia Neonatorum; Benzylamines; Brain; Bumetanide; Do

2021
Pyramidal neuron growth and increased hippocampal volume during labor and birth in autism.
    Science advances, 2019, Volume: 5, Issue:1

    Topics: Animals; Animals, Newborn; Autism Spectrum Disorder; Bumetanide; Dendrites; Disease Models, Animal;

2019
Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring.
    Science (New York, N.Y.), 2014, Feb-07, Volume: 343, Issue:6171

    Topics: Animals; Autistic Disorder; Behavior, Animal; Bumetanide; Chlorides; Cytoprotection; Disease Models,

2014
Heightened stress response and cognitive impairment after repeated neonatal sevoflurane exposures might be linked to excessive GABAAR-mediated depolarization.
    Journal of anesthesia, 2016, Volume: 30, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Bumetanide; Cognitive Dysfunction; Corticosteron

2016
Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons.
    Neurotoxicology, 2009, Volume: 30, Issue:1

    Topics: Animals; Bumetanide; Cells, Cultured; Chlorides; Female; Furosemide; GABA-A Receptor Agonists; Gadol

2009
Increased excitability and molecular changes in adult rats after a febrile seizure.
    Epilepsia, 2013, Volume: 54, Issue:4

    Topics: Animals; Blotting, Western; Bumetanide; Diuretics; Excitatory Amino Acid Agonists; Female; Hippocamp

2013
Intracellular acidification in neurons induced by ammonium depends on KCC2 function.
    The European journal of neuroscience, 2006, Volume: 23, Issue:2

    Topics: Animals; Bumetanide; Calcium; Calcium Channel Agonists; Cells, Cultured; Diagnostic Imaging; Dose-Re

2006
The effects of bumetanide on human umbilical artery contractions.
    Reproductive sciences (Thousand Oaks, Calif.), 2007, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Bumetanide; Female; Histamine; Humans; Muscle Contraction; Muscle, Smooth, Vascul

2007
NKCC1 cotransporter inactivation underlies embryonic development of chloride-mediated inhibition in mouse spinal motoneuron.
    The Journal of physiology, 2008, Feb-15, Volume: 586, Issue:4

    Topics: Action Potentials; Animals; Biophysical Phenomena; Biophysics; Bumetanide; Chlorides; Female; Furose

2008
Evidence for location of the CFTR in human placental apical membrane vesicles.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Anions; Bumetanide; Cell M

1995
Potassium efflux from infant and adult rat choroid plexuses: effects of CSF anion substitution, N-ethylmaleimide and Cl transport inhibitors.
    Neuroscience letters, 1994, Mar-14, Volume: 169, Issue:1-2

    Topics: Aging; Animals; Anions; Benzoates; Bumetanide; Chlorides; Choroid Plexus; Ethylmaleimide; Female; Fu

1994
Amiloride-sensitive sodium uptake into human placental brush border membrane vesicles.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Amiloride; Biological Transport, Active; Bumetanide; Cystic Fibrosis; Female; Humans; In Vitro Techn

1994
Lung fluid restriction affects growth but not airway branching of embryonic rat lung.
    The International journal of developmental biology, 1995, Volume: 39, Issue:4

    Topics: Aerobiosis; Animals; Body Fluids; Bumetanide; Culture Media, Serum-Free; DNA; Embryonic and Fetal De

1995
Transfer of Cl- across placenta of anesthetized rat.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Animals; Biological Transport; Bume

1996
Keratinocyte growth factor stimulates CFTR-independent fluid secretion in the fetal lung in vitro.
    The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Bumetanide; Carrier Proteins; Chlorides; Culture Techniques;

1996
Roles of Ca2+ and protein tyrosine kinase in insulin action on cell volume via Na+ and K+ channels and Na+/K+/2Cl- cotransporter in fetal rat alveolar type II pneumocyte.
    The Journal of membrane biology, 1999, Mar-01, Volume: 168, Issue:1

    Topics: Amiloride; Animals; Bumetanide; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Cell Size;

1999
The three mechanisms of intracellular chloride accumulation in vascular smooth muscle of human umbilical and placental arteries.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 441, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Antiporters; Arteries; Biological T

2000
K(+) transport in red blood cells from human umbilical cord.
    Biochimica et biophysica acta, 2001, Jun-06, Volume: 1512, Issue:2

    Topics: Acetates; Biological Transport; Bumetanide; Carrier Proteins; Chlorides; Erythrocyte Membrane; Eryth

2001
Ion transport regulation of lung liquid secretion in foetal lambs.
    Journal of developmental physiology, 1992, Volume: 17, Issue:2

    Topics: Amiloride; Animals; Biological Transport; Blood Pressure; Bumetanide; Chlorides; Epithelium; Exudate

1992
The effects of furosemide and bumetanide on lung liquid production by in vitro lungs from fetal guinea pigs.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:8

    Topics: Animals; Body Fluids; Bumetanide; Diuretics; Female; Fetus; Furosemide; Guinea Pigs; Lung; Pregnancy

1990
Effect of ouabain and bumetanide on the basal and the osmolality-affected prolactin secretion from human decidual cells in vitro.
    European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 23, Issue:3-4

    Topics: Bumetanide; Decidua; Diuretics; Female; Humans; In Vitro Techniques; Mannitol; Osmolar Concentration

1986