Page last updated: 2024-10-23

bumetanide and Neurodevelopmental Disorders

bumetanide has been researched along with Neurodevelopmental Disorders in 3 studies

Neurodevelopmental Disorders: These are a group of conditions with onset in the developmental period. The disorders typically manifest early in development, often before the child enters grade school, and are characterized by developmental deficits that produce impairments of personal, social, academic, or occupational functioning. (From DSM-5).

Research Excerpts

ExcerptRelevanceReference
"Bumetanide is a selective NKCC1 chloride importer antagonist which is being repurposed as a mechanism-based treatment for neurodevelopmental disorders (NDDs)."9.51Single-case experimental designs for bumetanide across neurodevelopmental disorders: BUDDI protocol. ( Bruining, H; Cristian, G; Geertjens, L; Haspels, E; Ramautar, J; van der Wilt, GJ; Verhage, M, 2022)
"Bumetanide treatment is a potential treatment to alleviate the behavioral burden and quality of life associated with TSC."6.94Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study. ( Bruining, H; Jansen, FE; Oranje, B; Scheepers, FE; Sprengers, JJ; van Andel, DM, 2020)
"Bumetanide is a selective NKCC1 chloride importer antagonist which is being repurposed as a mechanism-based treatment for neurodevelopmental disorders (NDDs)."5.51Single-case experimental designs for bumetanide across neurodevelopmental disorders: BUDDI protocol. ( Bruining, H; Cristian, G; Geertjens, L; Haspels, E; Ramautar, J; van der Wilt, GJ; Verhage, M, 2022)
"Before we elaborate on the postulated discrepancies between our trial and previous bumetanide in autism spectrum disorder (ASD) trials, we would like to acknowledge the crucial pioneering work on the γ-aminobutyric acid (GABA) developmental sequence by Dr."4.02Dr. Sprengers et al. Reply. ( Bruining, H; Sprengers, JJ; van Andel, DM, 2021)
"Bumetanide treatment is a potential treatment to alleviate the behavioral burden and quality of life associated with TSC."2.94Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study. ( Bruining, H; Jansen, FE; Oranje, B; Scheepers, FE; Sprengers, JJ; van Andel, DM, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Geertjens, L1
Cristian, G1
Haspels, E1
Ramautar, J1
van der Wilt, GJ1
Verhage, M1
Bruining, H3
van Andel, DM2
Sprengers, JJ2
Oranje, B1
Scheepers, FE1
Jansen, FE1

Trials

2 trials available for bumetanide and Neurodevelopmental Disorders

ArticleYear
Single-case experimental designs for bumetanide across neurodevelopmental disorders: BUDDI protocol.
    BMC psychiatry, 2022, 07-07, Volume: 22, Issue:1

    Topics: Bumetanide; Child; Cohort Studies; Humans; Neurodevelopmental Disorders; Research Design; Treatment

2022
Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study.
    Molecular autism, 2020, 05-07, Volume: 11, Issue:1

    Topics: Adolescent; Autism Spectrum Disorder; Bumetanide; Child; Disease Susceptibility; Duration of Therapy

2020

Other Studies

1 other study available for bumetanide and Neurodevelopmental Disorders

ArticleYear
Dr. Sprengers et al. Reply.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2021, Volume: 60, Issue:8

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Bumetanide; gamma-Aminobutyric Acid; Humans; N

2021