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bumetanide and Ischemia

bumetanide has been researched along with Ischemia in 4 studies

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" We hypothesized that NKCC1 is highly expressed on oligodendrocytes (OLs) and increases vulnerability to hypoxia-ischemia (HI) mediated white matter injury, and that the NKCC1 inhibitor bumetanide would be protective in a rodent PVL model."3.81Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia. ( Hu, MY; Jackson, MC; Jantzie, LL; Jensen, FE; Maxwell, JR; Park, HK; Yu, J, 2015)
" Therefore, the objective of the present study was to directly investigate the role of ClC-2 in mucosal repair by evaluating mucosal recovery in ischemia-injured intestinal mucosa treated with the selective ClC-2 agonist lubiprostone."3.74Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. ( Blikslager, AT; Engelke, KJ; Moeser, AJ; Nighot, PK; Ueno, R, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Machado, DN1
DurĂ¡n-Carabali, LE1
Odorcyk, FK1
Carvalho, AVS1
Martini, APR1
Schlemmer, LM1
de Mattos, MM1
Bernd, GP1
Dalmaz, C1
Netto, CA1
Jantzie, LL1
Hu, MY1
Park, HK1
Jackson, MC1
Yu, J1
Maxwell, JR1
Jensen, FE1
Moeser, AJ1
Nighot, PK1
Engelke, KJ1
Ueno, R1
Blikslager, AT1
Fiegen, RJ1
Rauen, U1
Hartmann, M1
Decking, UK1
de Groot, H1

Other Studies

4 other studies available for bumetanide and Ischemia

ArticleYear
Bumetanide Attenuates Cognitive Deficits and Brain Damage in Rats Subjected to Hypoxia-Ischemia at Two Time Points of the Early Postnatal Period.
    Neurotoxicity research, 2023, Volume: 41, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Bumetanide; Cognition; Hypoxia; Hypoxia-Ischemia, Brain; Ischemia;

2023
Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia.
    Pediatric research, 2015, Volume: 77, Issue:4

    Topics: Animals; Bumetanide; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Hypoxia; I

2015
Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2

    Topics: Alprostadil; Animals; Bumetanide; Chloride Channel Agonists; Chloride Channels; Chlorides; CLC-2 Chl

2007
Decrease of ischemic injury to the isolated perfused rat liver by loop diuretics.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Bile; Bumetanide; Carrier Proteins; Diuretics; Furosemide; Glu

1997