Page last updated: 2024-10-23

bumetanide and Glioma

bumetanide has been researched along with Glioma in 15 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to investigate the effect of bumetanide on peri-tumor edema caused by photodynamic therapy (PDT) of intraparenchymal C6 glioma xenografts."7.80The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts. ( Chen, L; Cong, D; Gao, X; Hu, S; Shen, D; Zhang, X, 2014)
"A perifusion technique for microscopy with computerized detection of early changes in cell morphology during continuous perifusion was used to show that the geometry of cultured glioma cells (MG-251) changes rapidly when they are exposed to estramustine phosphate (EMP)."7.69Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion. ( Behnam-Motlagh, P; Engström, KG; Grankvist, K; Henriksson, R; Jonsson, O, 1997)
"The aim of this study was to investigate the effect of bumetanide on peri-tumor edema caused by photodynamic therapy (PDT) of intraparenchymal C6 glioma xenografts."3.80The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts. ( Chen, L; Cong, D; Gao, X; Hu, S; Shen, D; Zhang, X, 2014)
"Swelling of C6 glioma cells in hypotonic medium (180 mOsm) results in two- to three-fold activation of K+ (86Rb+) influx suppressed by 10 microM bumetanide."3.69Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms. ( Aksentsev, SL; Fedulov, AS; Konev, SV; Kvacheva, ZB; Mezen, NI; Mongin, AA; Orlov, SN, 1996)
"A perifusion technique for microscopy with computerized detection of early changes in cell morphology during continuous perifusion was used to show that the geometry of cultured glioma cells (MG-251) changes rapidly when they are exposed to estramustine phosphate (EMP)."3.69Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion. ( Behnam-Motlagh, P; Engström, KG; Grankvist, K; Henriksson, R; Jonsson, O, 1997)
"Among the most prevalent and deadly primary brain tumors, high-grade gliomas evade complete surgical resection by diffuse invasion into surrounding brain parenchyma."1.37With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. ( Cuddapah, VA; Dy, TE; Haas, BR; Rohn, KJ; Sontheimer, H; Watkins, S, 2011)
"Amiloride and mannitol were found effective in reducing the lactic acidosis-induced cellular swelling."1.29Mechanism of cellular swelling induced by extracellular lactic acidosis in neuroblastoma-glioma hybrid (NG108-15) cells. ( Alojado, ME; Kemmotsu, O; Morimoto, Y, 1996)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's8 (53.33)18.2507
2000's1 (6.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, X1
Cong, D1
Shen, D1
Gao, X1
Chen, L1
Hu, S1
MacKenzie, G1
O'Toole, KK1
Moss, SJ1
Maguire, J1
Haas, BR2
Sontheimer, H2
Cuddapah, VA1
Watkins, S1
Rohn, KJ1
Dy, TE1
Garzon-Muvdi, T1
Schiapparelli, P1
ap Rhys, C1
Guerrero-Cazares, H1
Smith, C1
Kim, DH1
Kone, L1
Farber, H1
Lee, DY1
An, SS1
Levchenko, A1
Quiñones-Hinojosa, A1
Brismar, T1
Anderson, S1
Collins, VP1
Sandström, PE1
Jonsson, O2
Grankvist, K2
Henriksson, R2
O'Donnell, ME1
Martinez, A1
Sun, D1
McManus, ML1
Strange, K1
Alojado, ME1
Morimoto, Y2
Kemmotsu, O1
Mongin, AA1
Aksentsev, SL1
Orlov, SN1
Kvacheva, ZB1
Mezen, NI1
Fedulov, AS1
Konev, SV1
Mountian, I1
Van Driessche, W1
Behnam-Motlagh, P1
Engström, KG1
Ringel, F1
Chang, RC1
Staub, F1
Baethmann, A1
Plesnila, N1
Chassande, O1
Frelin, C1
Farahifar, D1
Jean, T1
Lazdunski, M1

Other Studies

15 other studies available for bumetanide and Glioma

ArticleYear
The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts.
    Lasers in surgery and medicine, 2014, Volume: 46, Issue:5

    Topics: Animals; Biomarkers; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Diuretics; Edema; Glioma; Hemato

2014
Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
    Epilepsy research, 2016, Volume: 126

    Topics: Animals; Brain; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Disease Models, Animal; Epilepsy; gam

2016
Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 reduces glioma invasion.
    Cancer research, 2010, Jul-01, Volume: 70, Issue:13

    Topics: Animals; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Cell Movement; Female; Gene Knockdown Techni

2010
With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:5

    Topics: Brain Neoplasms; Bumetanide; Cell Line, Tumor; Cell Size; Glioma; Humans; Intracellular Signaling Pe

2011
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation.
    PLoS biology, 2012, Volume: 10, Issue:5

    Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Bumetanide; Cell Movement; Cell Size; Cloning, Molecu

2012
Mechanism of high K+ and Tl+ uptake in cultured human glioma cells.
    Cellular and molecular neurobiology, 1995, Volume: 15, Issue:3

    Topics: Barium; Biological Transport; Bumetanide; Bupivacaine; Cell Line; Cesium; Dinitrophenols; Glioma; Hu

1995
Identification of potassium flux pathways and their role in the cytotoxicity of estramustine in human malignant glioma, prostatic carcinoma and pulmonary carcinoma cell lines.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:12

    Topics: Bumetanide; Cell Division; Estramustine; Furosemide; Glioma; Humans; Ion Transport; Lung Neoplasms;

1994
Cerebral microvascular endothelial cell Na-K-Cl cotransport: regulation by astrocyte-conditioned medium.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 1

    Topics: Animals; Aorta; Astrocytes; Brain; Bumetanide; Calcimycin; Carrier Proteins; Cattle; Culture Media,

1995
Acute volume regulation of brain cells in response to hypertonic challenge.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Animals; Brain Neoplasms; Bumetanide; Cell Size; Chlorides; Glioma; Hypertonic Solutions; In Vitro T

1993
Mechanism of cellular swelling induced by extracellular lactic acidosis in neuroblastoma-glioma hybrid (NG108-15) cells.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Acidosis, Lactic; Amiloride; Animals; Bumetanide; Cell Size; Cytological Techniques; Diuretics; Diur

1996
Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms.
    Biochimica et biophysica acta, 1996, Dec-04, Volume: 1285, Issue:2

    Topics: Bumetanide; Carrier Proteins; Cell Size; Chlorides; Diuretics; Glioma; Hypotonic Solutions; Ion Exch

1996
Isovolumetric regulation of C6 rat glioma cells in hyperosmotic media.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: Acids; Amiloride; Animals; Bumetanide; Carrier Proteins; Culture Media; Enzyme Inhibitors; Extracell

1997
Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion.
    British journal of cancer, 1997, Volume: 76, Issue:3

    Topics: Bumetanide; Cell Size; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estramustine; Furosemide

1997
Contribution of anion transporters to the acidosis-induced swelling and intracellular acidification of glial cells.
    Journal of neurochemistry, 2000, Volume: 75, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Antiporters; Bicarbonates; Bumeta

2000
The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.
    European journal of biochemistry, 1988, Feb-01, Volume: 171, Issue:3

    Topics: Biological Transport; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Flow Cytometry; Furo

1988