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bumetanide and Edema

bumetanide has been researched along with Edema in 26 studies

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"A pharmacokinetic study was undertaken to determine the bioavailability of bumetanide in grossly oedematous patients."9.06Bioavailability of bumetanide in grossly oedematous patients. ( Bailie, GR; Grennan, A; Waldek, S, 1987)
"The efficacy and safety of oral bumetanide, a pharmacologically new diuretic was compared with that of furosemide in 30 patients suffering from congestive cardiac failure and other edema states."9.05A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states. ( Sagar, S; Sharma, BK; Sharma, PL; Wahi, PL, 1984)
"In a crossover study bumetanide, 2 to 6 mg/d, was compared with furosemide, 40 to 160 mg/d, in the treatment of 10 patients with the nephrotic syndrome and massive edema."9.05Treatment of nephrotic edema with bumetanide. ( Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P, 1981)
"The aim of this study was to investigate the effect of bumetanide on peri-tumor edema caused by photodynamic therapy (PDT) of intraparenchymal C6 glioma xenografts."7.80The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts. ( Chen, L; Cong, D; Gao, X; Hu, S; Shen, D; Zhang, X, 2014)
"Bumetanide (BU) has potential efficacy against cytotoxic oedema."5.91Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury. ( Chen, C; Fan, P; Gan, S; Hu, J; Huang, J; Lu, W; Qiu, G; Ran, J; Xu, J; Xu, S; Xue, K; Zhang, L, 2023)
"Cell edema was assessed in sections of rabbit esophageal epithelium by correlating morphological change with change in tissue wet weight after immersion in acidic solutions for up to 4 hours."5.29HCl-induced cell edema in rabbit esophageal epithelium: a bumetanide-sensitive process. ( Cragoe, EJ; Orlando, RC; Tobey, NA, 1995)
"Bumetanide2 is a new diuretic with a rapid onset and short duration of action."5.25Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema. ( Avery, GS; Brogden, RN; Speight, TM, 1975)
"This prospective, open-label, clinical trial was conducted to describe the pharmacology of bumetanide in pediatric patients with edema."5.08Pharmacokinetics and pharmacodynamics of bumetanide in critically ill pediatric patients. ( Kearns, GL; Letzig, L; Marshall, JD; Wells, TG, 1998)
"A pharmacokinetic study was undertaken to determine the bioavailability of bumetanide in grossly oedematous patients."5.06Bioavailability of bumetanide in grossly oedematous patients. ( Bailie, GR; Grennan, A; Waldek, S, 1987)
"The efficacy and safety of oral bumetanide, a pharmacologically new diuretic was compared with that of furosemide in 30 patients suffering from congestive cardiac failure and other edema states."5.05A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states. ( Sagar, S; Sharma, BK; Sharma, PL; Wahi, PL, 1984)
"In a crossover study bumetanide, 2 to 6 mg/d, was compared with furosemide, 40 to 160 mg/d, in the treatment of 10 patients with the nephrotic syndrome and massive edema."5.05Treatment of nephrotic edema with bumetanide. ( Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P, 1981)
"The aim of this study was to investigate the effect of bumetanide on peri-tumor edema caused by photodynamic therapy (PDT) of intraparenchymal C6 glioma xenografts."3.80The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts. ( Chen, L; Cong, D; Gao, X; Hu, S; Shen, D; Zhang, X, 2014)
"Bumetanide and frusemide were compared in a crossover study of 10 patients with cirrhosis and fluid overload."2.64Treatment of fluid retention in cirrhosis: a comparison of bumetanide and frusemide. ( Nicholson, G, 1977)
"Bumetanide (BU) has potential efficacy against cytotoxic oedema."1.91Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury. ( Chen, C; Fan, P; Gan, S; Hu, J; Huang, J; Lu, W; Qiu, G; Ran, J; Xu, J; Xu, S; Xue, K; Zhang, L, 2023)
"Cell edema was assessed in sections of rabbit esophageal epithelium by correlating morphological change with change in tissue wet weight after immersion in acidic solutions for up to 4 hours."1.29HCl-induced cell edema in rabbit esophageal epithelium: a bumetanide-sensitive process. ( Cragoe, EJ; Orlando, RC; Tobey, NA, 1995)
"Forty patients with generalized cancer complicated by water and electrolyte retention were treated with "medium" and "large" doses of furosemide and bumetanide with 35% and 40% objective positive response, respectively."1.26Diuretics in malignant effusions and edemas of generalized cancer. ( Athanasiou, A; Dadiotis, L; Razis, DV, 1976)
"Bumetanide2 is a new diuretic with a rapid onset and short duration of action."1.25Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema. ( Avery, GS; Brogden, RN; Speight, TM, 1975)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199021 (80.77)18.7374
1990's2 (7.69)18.2507
2000's0 (0.00)29.6817
2010's1 (3.85)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Chen, C2
Fan, P2
Zhang, L2
Xue, K2
Hu, J2
Huang, J2
Lu, W2
Xu, J2
Xu, S2
Qiu, G2
Ran, J2
Gan, S2
Ibrahim, TS1
Salem, IM1
Mostafa, SM1
El-Sabbagh, OI1
ElKhamisi, MKM1
Hegazy, L1
Elgendy, B1
Zhang, X1
Cong, D1
Shen, D1
Gao, X1
Chen, L1
Hu, S1
Sagar, S1
Sharma, BK1
Sharma, PL1
Wahi, PL1
Gulati, PD1
Sood, KC1
Singh, G1
Dass, R1
Razvi, SN1
Davies, IB1
Lightman, SL1
Lemieux, G1
Beauchemin, M1
Gougoux, A1
Vinay, P1
Pellerito, R1
Bertola, D1
Soragna, A1
Tobey, NA1
Cragoe, EJ1
Orlando, RC1
Marshall, JD1
Wells, TG1
Letzig, L1
Kearns, GL1
Bourke, E1
Nicholson, G1
Santi, PA1
Duvall, AJ1
Sugino, N1
Kym, V1
Binswanger, U1
Hofstetter, A1
Kelly, TW1
Alton, BG1
Razis, DV1
Athanasiou, A1
Dadiotis, L1
Murdoch, WR1
Auld, WH1
Brogden, RN1
Speight, TM1
Avery, GS1
Johnson, CA1
Grant, KL1
Madalon, MG1
Bailie, GR1
Grennan, A1
Waldek, S1
Darlington, LG1
Pines, A1
Sreedharan, KS1
Nandi, AR1
Marsh, BT1

Reviews

1 review available for bumetanide and Edema

ArticleYear
Refractory oedema.
    British journal of hospital medicine, 1980, Volume: 23, Issue:3

    Topics: Aminophylline; Bumetanide; Diuretics; Drug Therapy, Combination; Edema; Edema, Cardiac; Ethacrynic A

1980

Trials

8 trials available for bumetanide and Edema

ArticleYear
A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Bumetanide; Clinical Trials as Topic; Diuretics; Doub

1984
Evaluation of bumetanide--a new diuretic in oedematous states.
    The Journal of the Association of Physicians of India, 1981, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Bumetanide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Edema; Fema

1981
Treatment of nephrotic edema with bumetanide.
    Canadian Medical Association journal, 1981, Nov-15, Volume: 125, Issue:10

    Topics: Adolescent; Adult; Aged; Body Weight; Bumetanide; Clinical Trials as Topic; Diuretics; Edema; Female

1981
Pharmacokinetics and pharmacodynamics of bumetanide in critically ill pediatric patients.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:11

    Topics: Adult; Alkalosis; Area Under Curve; Bumetanide; Child; Child, Preschool; Chlorides; Creatine; Critic

1998
Treatment of fluid retention in cirrhosis: a comparison of bumetanide and frusemide.
    Current medical research and opinion, 1977, Volume: 4, Issue:9

    Topics: Adult; Aged; Ascites; Bumetanide; Clinical Trials as Topic; Diuretics; Edema; Female; Furosemide; Hu

1977
Bumetanide--acute and long-term studies of a new high potency diuretic.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 6

    Topics: Adult; Aged; Bumetanide; Clinical Trials as Topic; Diuretics; Drug Evaluation; Edema; Female; Furose

1975
Bioavailability of bumetanide in grossly oedematous patients.
    Clinical pharmacokinetics, 1987, Volume: 12, Issue:6

    Topics: Aged; Biological Availability; Bumetanide; Diuretics; Edema; Female; Half-Life; Humans; Male; Middle

1987
New diuretics - bumetanide and metolazone.
    Drug and therapeutics bulletin, 1974, Jun-21, Volume: 12, Issue:13

    Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Edema; Humans; Metolazone

1974

Other Studies

17 other studies available for bumetanide and Edema

ArticleYear
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
    Neuroscience, 2023, 02-01, Volume: 510

    Topics: Animals; Aquaporin 4; Bumetanide; Dystroglycans; Edema; Matrix Metalloproteinase 9; Neuroprotection;

2023
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
    Neuroscience, 2023, 02-01, Volume: 510

    Topics: Animals; Aquaporin 4; Bumetanide; Dystroglycans; Edema; Matrix Metalloproteinase 9; Neuroprotection;

2023
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
    Neuroscience, 2023, 02-01, Volume: 510

    Topics: Animals; Aquaporin 4; Bumetanide; Dystroglycans; Edema; Matrix Metalloproteinase 9; Neuroprotection;

2023
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
    Neuroscience, 2023, 02-01, Volume: 510

    Topics: Animals; Aquaporin 4; Bumetanide; Dystroglycans; Edema; Matrix Metalloproteinase 9; Neuroprotection;

2023
Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Animals; Anti-Inflammatory Agents; Benzenesulfonamides; Bumetanide; Catalytic Domain; Cyclooxygenase

2020
The effect of bumetanide on photodynamic therapy-induced peri-tumor edema of C6 glioma xenografts.
    Lasers in surgery and medicine, 2014, Volume: 46, Issue:5

    Topics: Animals; Biomarkers; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Diuretics; Edema; Glioma; Hemato

2014
Drugs and dosages: Bumex.
    Occupational health nursing, 1983, Volume: 31, Issue:8

    Topics: Bumetanide; Diuretics; Edema; Humans

1983
[Clinical use of bumetanide].
    La Clinica terapeutica, 1981, Sep-30, Volume: 98, Issue:6

    Topics: Blood Pressure; Bumetanide; Diuresis; Diuretics; Edema; Electrolytes; Female; Heart Failure; Humans;

1981
HCl-induced cell edema in rabbit esophageal epithelium: a bumetanide-sensitive process.
    Gastroenterology, 1995, Volume: 109, Issue:2

    Topics: Animals; Body Water; Bumetanide; Chlorides; Edema; Esophagus; Hydrochloric Acid; Ion Transport; Osmo

1995
Letter: Frusemide, bumetanide, and ototoxicity.
    Lancet (London, England), 1976, Apr-24, Volume: 1, Issue:7965

    Topics: Bumetanide; Deafness; Diuretics; Edema; Female; Furosemide; Humans; Hyperparathyroidism; Male; Middl

1976
Morphological alteration of the stria vascularis after administration of the diuretic bumetanide.
    Acta oto-laryngologica, 1979, Volume: 88, Issue:1-2

    Topics: Animals; Bumetanide; Capillaries; Cell Membrane; Chinchilla; Cochlea; Diuretics; Edema; Stria Vascul

1979
[Symposium on edema. (2) Clinics of edema. VI) Treatment--diuretics and refractory edema (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Nov-10, Volume: 67, Issue:11

    Topics: Bumetanide; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans

1978
[Trial of the diuretic agent bumetanid (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1979, Jan-23, Volume: 68, Issue:4

    Topics: Adult; Aged; Bumetanide; Cardiovascular Diseases; Diuretics; Drug Evaluation; Edema; Female; Gastroi

1979
[New drugs: Fordiuran (Bumetanide)].
    Der Urologe. Ausg. A, 1977, Volume: 16, Issue:2

    Topics: Bumetanide; Chemical Phenomena; Chemistry; Diuretics; Edema; Humans

1977
Diuretic therapy in the elderly with a bumetanide/potassium combination.
    Irish medical journal, 1976, Nov-13, Volume: 69, Issue:18

    Topics: Aged; Bumetanide; Diuretics; Drug Therapy, Combination; Edema; Female; Humans; Male; Potassium

1976
Diuretics in malignant effusions and edemas of generalized cancer.
    Journal of medicine, 1976, Volume: 7, Issue:6

    Topics: Ascites; Body Weight; Bumetanide; Diuretics; Drinking; Edema; Furosemide; Humans; Neoplasms; Pleuris

1976
Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema.
    Drugs, 1975, Volume: 9, Issue:1

    Topics: Animals; Ascites; Bumetanide; Diuresis; Dogs; Drug Incompatibility; Edema; Heart Failure; Humans; Ki

1975
Severe musculoskeletal syndrome in patients with renal failure and hypoalbuminemia receiving bumetanide.
    Clinical pharmacy, 1987, Volume: 6, Issue:9

    Topics: Adult; Aged; Bone Diseases; Bumetanide; Diuretics; Edema; Female; Graft Rejection; Humans; Kidney Di

1987
Study to compare the relative hyperuricaemic effects of frusemide and bumetanide.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Aged; Bumetanide; Diuretics; Edema; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; M

1986
A clinical assessment of bumetanide in patients not responding to other diuretics.
    The British journal of clinical practice, 1974, Volume: 28, Issue:9

    Topics: Aged; Bumetanide; Diuretics; Edema; Electrolytes; Female; Heart Failure; Humans; Male; Middle Aged;

1974