bumetanide has been researched along with Cystic Fibrosis of Pancreas in 21 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the loop diuretic bumetanide on Cl- transport in the human reabsorptive sweat duct (RSD) was studied to determine the properties of Cl- transport in this tissue with an emphasis on its role in cystic fibrosis." | 7.67 | Effects of bumetanide on chloride transport in human eccrine sweat ducts: implications for cystic fibrosis. ( Quinton, PM; Reddy, MM, 1987) |
| " In our pursuit to identify potent modulators of Cl(-) secretion that may be useful to overcome the Cl(-) secretory defect in cystic fibrosis (CF), we have identified chlorzoxazone [5-chloro-2(3H)-benzoxazolone], a clinically used centrally acting muscle relaxant, as a stimulator of Cl(-) secretion in several epithelial cell types, including T84, Calu-3, and human bronchial epithelium." | 3.70 | Stimulation of Cl(-) secretion by chlorzoxazone. ( Bridges, RJ; Devor, DC; Gerlach, AC; Gondor, M; Pilewski, JM; Singh, AK, 2000) |
| "To investigate cellular mechanisms involved in the regulation of basolateral Na-K-Cl cotransport in airway epithelia, we determined saturable basolateral [3H]bumetanide binding, a measure of functioning cotransporters, in primary cultures of canine tracheal and human nasal epithelial cells, including cells from patients with cystic fibrosis (CF)." | 3.68 | Dual mechanisms for Na-K-Cl cotransport regulation in airway epithelial cells. ( Haas, M; McBrayer, DG; Yankaskas, JR, 1993) |
| "Cystic fibrosis (CF) airway epithelia exhibit raised transepithelial Na+ transport rates, as determined by open-circuit isotope fluxes and estimates of the amiloride-sensitive equivalent short-circuit current (Ieq)." | 3.68 | Transcellular sodium transport in cultured cystic fibrosis human nasal epithelium. ( Boucher, RC; Willumsen, NJ, 1991) |
| "The effect of the loop diuretic bumetanide on Cl- transport in the human reabsorptive sweat duct (RSD) was studied to determine the properties of Cl- transport in this tissue with an emphasis on its role in cystic fibrosis." | 3.67 | Effects of bumetanide on chloride transport in human eccrine sweat ducts: implications for cystic fibrosis. ( Quinton, PM; Reddy, MM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, WJ | 1 |
| Goeckeler-Fried, JL | 1 |
| Havasi, V | 1 |
| Chiang, A | 1 |
| Rowe, SM | 1 |
| Plyler, ZE | 1 |
| Hong, JS | 1 |
| Mazur, M | 1 |
| Piazza, GA | 1 |
| Keeton, AB | 1 |
| White, EL | 1 |
| Rasmussen, L | 1 |
| Weissman, AM | 1 |
| Denny, RA | 1 |
| Brodsky, JL | 1 |
| Sorscher, EJ | 1 |
| Abdullah, LH | 1 |
| Evans, JR | 1 |
| Wang, TT | 1 |
| Ford, AA | 1 |
| Makhov, AM | 1 |
| Nguyen, K | 1 |
| Coakley, RD | 1 |
| Griffith, JD | 1 |
| Davis, CW | 2 |
| Ballard, ST | 2 |
| Kesimer, M | 1 |
| Saint-Criq, V | 1 |
| Kim, SH | 1 |
| Katzenellenbogen, JA | 1 |
| Harvey, BJ | 1 |
| Jeong, JH | 1 |
| Joo, NS | 1 |
| Hwang, PH | 1 |
| Wine, JJ | 1 |
| Garcia, MA | 1 |
| Yang, N | 1 |
| Quinton, PM | 3 |
| Trout, L | 2 |
| Townsley, MI | 1 |
| Bowden, AL | 1 |
| Tarran, R | 1 |
| Donaldson, SH | 1 |
| Boucher, RC | 3 |
| Grubb, BR | 1 |
| Faller, DP | 2 |
| Egan, DA | 1 |
| Ryan, MP | 2 |
| Slotki, IN | 1 |
| Breuer, WV | 1 |
| Greger, R | 1 |
| Cabantchik, ZI | 1 |
| O'Reilly, CM | 1 |
| Haas, M | 1 |
| McBrayer, DG | 1 |
| Yankaskas, JR | 1 |
| Clarke, LL | 1 |
| Harline, MC | 1 |
| Devor, DC | 2 |
| Pilewski, JM | 2 |
| Singh, AK | 1 |
| Gerlach, AC | 1 |
| Gondor, M | 1 |
| Bridges, RJ | 1 |
| Liedtke, CM | 1 |
| Papay, R | 1 |
| Cole, TS | 1 |
| Smith, SN | 1 |
| Alton, EW | 1 |
| Geddes, DM | 1 |
| Bell, CL | 1 |
| Willumsen, NJ | 2 |
| Reddy, MM | 1 |
21 other studies available for bumetanide and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways.
Topics: Amiloride; Animals; Bronchi; Bumetanide; Cells, Cultured; Cystic Fibrosis; Humans; In Vitro Techniqu | 2017 |
Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium.
Topics: Amiloride; Bronchi; Bumetanide; Cell Line; Colforsin; Cyclic AMP; Cystic Fibrosis; Epithelial Cells; | 2013 |
Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea.
Topics: Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Bronchodilator Agents; Bumetanide; Calci | 2014 |
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Bumetanide; Cystic Fibrosis | 2009 |
Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lung.
Topics: Adrenergic beta-Agonists; Algorithms; Amiloride; Animals; Anions; Bethanechol; Bicarbonates; Bronchi | 2003 |
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.
Topics: Adenosine; Adenosine Triphosphate; Aprotinin; Bronchi; Bumetanide; Cells, Cultured; Chlorides; Cilia | 2006 |
Ion transport across the jejunum in normal and cystic fibrosis mice.
Topics: Animals; Bicarbonates; Bumetanide; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Electric Condu | 1995 |
Evidence for location of the CFTR in human placental apical membrane vesicles.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Anions; Bumetanide; Cell M | 1995 |
Long-term cAMP activation of Na(+)-K(+)-2Cl- cotransporter activity in HT-29 human adenocarcinoma cells.
Topics: Adenocarcinoma; Bumetanide; Carrier Proteins; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; C | 1993 |
Amiloride-sensitive sodium uptake into human placental brush border membrane vesicles.
Topics: Amiloride; Biological Transport, Active; Bumetanide; Cystic Fibrosis; Female; Humans; In Vitro Techn | 1994 |
Dual mechanisms for Na-K-Cl cotransport regulation in airway epithelial cells.
Topics: Adenosine Triphosphate; Animals; Bumetanide; Carrier Proteins; Cells, Cultured; Cystic Fibrosis; Dog | 1993 |
CFTR is required for cAMP inhibition of intestinal Na+ absorption in a cystic fibrosis mouse model.
Topics: Animals; Bicarbonates; Bumetanide; Calcium; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cystic | 1996 |
UTP inhibits Na+ absorption in wild-type and DeltaF508 CFTR-expressing human bronchial epithelia.
Topics: Amiloride; Biological Transport; Bronchi; Bumetanide; Calcium; Cells, Cultured; Chlorides; Cystic Fi | 1999 |
Stimulation of Cl(-) secretion by chlorzoxazone.
Topics: Amiloride; Anions; Bronchi; Bumetanide; Cell Membrane; Cells, Cultured; Charybdotoxin; Chlorine; Chl | 2000 |
Modulation of Na-K-2Cl cotransport by intracellular Cl(-) and protein kinase C-delta in Calu-3 cells.
Topics: Acetophenones; Adrenergic alpha-Agonists; Benzopyrans; Biological Transport; Bumetanide; Cells, Cult | 2002 |
Ion transport characteristics of the murine trachea and caecum.
Topics: Amiloride; Animals; Bumetanide; Cecum; Chlorides; Colforsin; Cystic Fibrosis; Electric Conductivity; | 1992 |
T84 cells: anion selectivity demonstrates expression of Cl- conductance affected in cystic fibrosis.
Topics: Amiloride; Anions; Azides; Bumetanide; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cystic F | 1992 |
Transcellular sodium transport in cultured cystic fibrosis human nasal epithelium.
Topics: Adolescent; Adult; Amiloride; Amphotericin B; Biological Transport; Bumetanide; Cells, Cultured; Chi | 1991 |
Cellular Cl- transport in cultured cystic fibrosis airway epithelium.
Topics: Adolescent; Adult; Amiloride; Biological Transport; Bumetanide; Cells, Cultured; Child; Child, Presc | 1989 |
Effects of bumetanide on chloride transport in human eccrine sweat ducts: implications for cystic fibrosis.
Topics: Absorption; Bumetanide; Cystic Fibrosis; Diuretics; Eccrine Glands; Epithelium; Humans; In Vitro Tec | 1987 |