Page last updated: 2024-10-23

bumetanide and Cardiac Failure

bumetanide has been researched along with Cardiac Failure in 76 studies

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of acetazolamide on natriuresis, decongestion, kidney function and neurohumoral activation in acute heart failure (AHF)."9.30Acetazolamide to increase natriuresis in congestive heart failure at high risk for diuretic resistance. ( Ameloot, K; Droogné, W; Dupont, M; Haemels, V; Martens, P; Mullens, W; Penders, J; Tang, WHW; Verbrugge, FH, 2019)
"Four healthy subjects and six patients with congestive heart failure (CHF) were given 3 mg oral and intravenous doses of bumetanide in a random crossover fashion."9.06Kinetics, dynamics, and bioavailability of bumetanide in healthy subjects and patients with congestive heart failure. ( Cook, JA; Cornish, LA; Hyneck, ML; Nicklas, JM; Smith, DE; Tankanow, RM, 1988)
" bumetanide (25 micrograms kg-1) were prospectively studied in 24 patients with angiographically documented coronary artery disease and either acute exercise-induced (Group I, n = 12) or chronic (Group II, n = 12) heart failure."9.06Immediate effects of bumetanide on systemic haemodynamics and left ventricular volume in acute and chronic heart failure. ( Frais, MA; Muller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1987)
"Forty elderly patients, aged 68 to 89 years, with congestive cardiac failure, who were attending a hospital out-patients department, entered an open, parallel group, comparative study of two diuretic combinations, 40 mg frusemide plus 5 mg amiloride per tablet and 0."9.06An open comparative study of two diuretic combinations, frusemide/amiloride ('Frumil') and bumetanide/potassium chloride ('Burinex' K), in the treatment of congestive cardiac failure in hospital out-patients. ( Allman, S; Bailey, R; Crawford, RJ; Martin, A; Ramsay, F, 1988)
"The efficacy and safety of oral bumetanide, a pharmacologically new diuretic was compared with that of furosemide in 30 patients suffering from congestive cardiac failure and other edema states."9.05A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states. ( Sagar, S; Sharma, BK; Sharma, PL; Wahi, PL, 1984)
"0 mg) and to furosemide (40 and 80 mg) in 20 patients with stable, compensated congestive heart failure (CHF), comparing the two drugs and, in addition, examining differences from normal subjects."9.05Bumetanide and furosemide in heart failure. ( Anderson, S; Brater, DC; Burdette, A; Day, B, 1984)
"The additive natriuretic and diuretic effects of theophylline ethylenediamine and of bendroflumethiazide have been compared in permutation trial tests in patients with advanced congestive heart failure receiving long-term treatment with the highly potent diuretic, bumetanide."9.04Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure. ( Olesen, KH; Sigurd, B, 1978)
"Bumetanide, a new diuretic exerting its major effect on the ascending limb of the loop of Henle, was evaluated in 20 patients with congestive heart failure."9.04Bumetanide in congestive heart failure. ( Augoustakis, D; Christensen, O; Kourouklis, C, 1976)
"1 This study has compared the diuresis produced by a single oral administration of 6 mg piretanide, 9 mg piretanide and 1 mg bumetanide in a group of nine patients with cardiac failure using a balanced randomized design."9.04A single dose comparison of piretanide and bumetanide in congestive cardiac failure. ( Dombey, SL; Homeida, M; Roberts, CJ, 1979)
"Continuous intravenous (IV) infusion bumetanide has been associated with severe myalgia in case reports, and the package labeling lists a reported incidence of 0."7.91Evaluation of Severe Myalgia Induced by Continuous-Infusion Bumetanide in Patients with Acute Heart Failure. ( Chinaeke, EE; Cox, ZL; Lenihan, DJ; Lu, K; Merritt, TE; Xiong, L, 2019)
"Limited data exist comparing the efficacy and safety of bumetanide- or metolazone-based diuretic regimens to furosemide in acute heart failure (HF)."7.79Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. ( Elkayam, U; Han, SY; Hshieh, S; Hyderi, AF; Jeng, AI; Kim, BJ; Konopka, E; Lou, M; Ng, TM; Phan, DH; Tsuji, Y, 2013)
"To evaluate the effect of bumetanide, quinapril and a low-sodium diet on clinical response tolerance and side-effects on dogs with moderate congestive heart failure."7.71Effect of short-term treatment with bumetanide, quinapril and low-sodium diet on dogs with moderate congestive heart failure. ( Corbera, JA; Martinez-Alcaine, MA; Montoya, JA; Ynaraja, E, 2001)
"Two hundred and thirty-three patients (66 males and 167 females), aged 24 to 92 years, with congestive cardiac failure were entered into a long-term study to evaluate the efficacy and tolerability of treatment with a fixed dose combination tablet containing 1 mg bumetanide and 5 mg amiloride."7.68Bumetanide/amiloride ('Burinex A'): a new combined preparation for the control of patients with congestive cardiac failure. ( Hughes, IW; Lustman, F, 1990)
" We therefore measured lymphocyte free Mg2+ concentrations in patients with congestive cardiac failure treated with loop diuretics or a frusemide/amiloride mixture (Frumil) and compared them with control subjects."7.68Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics with and without amiloride. ( Brochwicz-Lewinski, MJ; Davies, JE; Garrido, MC; Ng, LL; Tan, LB, 1992)
"The hemodynamic variations brought about by the single intravenous infection of 0,5 mg bumetanide have been studied in 7 patients with chronic ischemic heart disease and in 3 patients with non-obstructive hypertrophic cardiomyopathy, all of them in congestive heart failure."7.66[Hemodynamic changes produced by intravenous bumetanide in congestive heart failure]. ( Lomanto, B; Rossi, A; Ziacchi, V, 1981)
"The effect of bumetanide in infants with congenital heart disease presenting with cardiac failure was studied."7.65Bumetanide in heart failure in infancy. ( Lam, LK; Ward, OC, 1977)
"It is recommended in severe congestive heart failure (HF)."6.71Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature. ( Galatius, S; Gustafsson, F; Hildebrandt, PR; Rosenberg, J, 2005)
"Mild congestive cardiac failure symptoms (raised jugular venous pressure, oedema and dyspnoea at rest and on effort) were controlled in 9/10 patients receiving frusemide/amiloride but two patients receiving bumetanide/potassium chloride still had mild oedema after 8 weeks."6.67An open, randomized comparative study of a low-strength frusemide/amiloride combination and bumetanide/potassium chloride in the treatment of mild congestive cardiac failure. ( Allman, S; Dalton, K; Finnamore, VP; Latta, D, 1990)
"Bumetanide is a potent 'loop' diuretic for the treatment of oedema associated with congestive heart failure, hepatic and renal diseases, acute pulmonary congestion and premenstrual syndrome and in forced diuresis during and after surgery."6.15Bumetanide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use. ( Heel, RC; Ward, A, 1984)
"To investigate the effects of acetazolamide on natriuresis, decongestion, kidney function and neurohumoral activation in acute heart failure (AHF)."5.30Acetazolamide to increase natriuresis in congestive heart failure at high risk for diuretic resistance. ( Ameloot, K; Droogné, W; Dupont, M; Haemels, V; Martens, P; Mullens, W; Penders, J; Tang, WHW; Verbrugge, FH, 2019)
"Patients with severe congestive heart failure (New York Heart Association [NYHA] functional classes III-IV) often can tolerate only low doses of angiotensin-converting enzyme (ACE) inhibitors because pronounced hypotension caused by additional ACE inhibitor increments may decrease renal perfusion."5.29Spironolactone in congestive heart failure refractory to high-dose loop diuretic and low-dose angiotensin-converting enzyme inhibitor. ( Donker, AJ; Nauta, JJ; van Vliet, AA; Verheugt, FW, 1993)
"Bumetanide2 is a new diuretic with a rapid onset and short duration of action."5.25Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema. ( Avery, GS; Brogden, RN; Speight, TM, 1975)
"We examined diuretic response (defined as Δ weight kg/40 mg furosemide) in 1745 hospitalized acute heart failure patients from the PROTECT trial."5.19Diuretic response in acute heart failure: clinical characteristics and prognostic significance. ( Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Dittrich, HC; Fiuzat, M; Givertz, MM; Hillege, HL; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Valente, MA; Van Veldhuisen, DJ; Voors, AA, 2014)
"Eight patients with mild heart failure were treated in random order for 1 week with 2 mg bumethanide at 0800 and 1200 (treatment 1) h, 1 mg bumethanide at 0800, 1200, 1800, 2200 (treatment 2) and 5 mg bendroflumethiazide at 0800 and 1800 (treatment 3) h."5.07A comparison of three diuretic regimens in heart failure. ( Andreasen, F; Bech, OM; Bruun, P; Diamant, B; Eriksen, UH; Guul, SJ; Hartling, OJ; Hvidt, S; Kahr, O; Nielsen, LP, 1993)
"Four healthy subjects and six patients with congestive heart failure (CHF) were given 3 mg oral and intravenous doses of bumetanide in a random crossover fashion."5.06Kinetics, dynamics, and bioavailability of bumetanide in healthy subjects and patients with congestive heart failure. ( Cook, JA; Cornish, LA; Hyneck, ML; Nicklas, JM; Smith, DE; Tankanow, RM, 1988)
"Forty elderly patients, aged 68 to 89 years, with congestive cardiac failure, who were attending a hospital out-patients department, entered an open, parallel group, comparative study of two diuretic combinations, 40 mg frusemide plus 5 mg amiloride per tablet and 0."5.06An open comparative study of two diuretic combinations, frusemide/amiloride ('Frumil') and bumetanide/potassium chloride ('Burinex' K), in the treatment of congestive cardiac failure in hospital out-patients. ( Allman, S; Bailey, R; Crawford, RJ; Martin, A; Ramsay, F, 1988)
" bumetanide (25 micrograms kg-1) were prospectively studied in 24 patients with angiographically documented coronary artery disease and either acute exercise-induced (Group I, n = 12) or chronic (Group II, n = 12) heart failure."5.06Immediate effects of bumetanide on systemic haemodynamics and left ventricular volume in acute and chronic heart failure. ( Frais, MA; Muller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1987)
"The clinical use of continuous bumetanide infusion for acute heart failure and volume overload is common."5.05Treatment outcomes of bumetanide continuous infusion: A systematic review and meta-analysis. ( Cheungpasitporn, W; Dimech, CT; Hansrivijit, P; Khanal, R; Techorueangwiwat, C; Thongprayoon, C, 2020)
"0 mg) and to furosemide (40 and 80 mg) in 20 patients with stable, compensated congestive heart failure (CHF), comparing the two drugs and, in addition, examining differences from normal subjects."5.05Bumetanide and furosemide in heart failure. ( Anderson, S; Brater, DC; Burdette, A; Day, B, 1984)
"The efficacy and safety of oral bumetanide, a pharmacologically new diuretic was compared with that of furosemide in 30 patients suffering from congestive cardiac failure and other edema states."5.05A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states. ( Sagar, S; Sharma, BK; Sharma, PL; Wahi, PL, 1984)
"Bumetanide, a new diuretic exerting its major effect on the ascending limb of the loop of Henle, was evaluated in 20 patients with congestive heart failure."5.04Bumetanide in congestive heart failure. ( Augoustakis, D; Christensen, O; Kourouklis, C, 1976)
"The additive natriuretic and diuretic effects of theophylline ethylenediamine and of bendroflumethiazide have been compared in permutation trial tests in patients with advanced congestive heart failure receiving long-term treatment with the highly potent diuretic, bumetanide."5.04Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure. ( Olesen, KH; Sigurd, B, 1978)
"1 This study has compared the diuresis produced by a single oral administration of 6 mg piretanide, 9 mg piretanide and 1 mg bumetanide in a group of nine patients with cardiac failure using a balanced randomized design."5.04A single dose comparison of piretanide and bumetanide in congestive cardiac failure. ( Dombey, SL; Homeida, M; Roberts, CJ, 1979)
"Continuous intravenous (IV) infusion bumetanide has been associated with severe myalgia in case reports, and the package labeling lists a reported incidence of 0."3.91Evaluation of Severe Myalgia Induced by Continuous-Infusion Bumetanide in Patients with Acute Heart Failure. ( Chinaeke, EE; Cox, ZL; Lenihan, DJ; Lu, K; Merritt, TE; Xiong, L, 2019)
"Limited data exist comparing the efficacy and safety of bumetanide- or metolazone-based diuretic regimens to furosemide in acute heart failure (HF)."3.79Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. ( Elkayam, U; Han, SY; Hshieh, S; Hyderi, AF; Jeng, AI; Kim, BJ; Konopka, E; Lou, M; Ng, TM; Phan, DH; Tsuji, Y, 2013)
"To evaluate the effect of bumetanide, quinapril and a low-sodium diet on clinical response tolerance and side-effects on dogs with moderate congestive heart failure."3.71Effect of short-term treatment with bumetanide, quinapril and low-sodium diet on dogs with moderate congestive heart failure. ( Corbera, JA; Martinez-Alcaine, MA; Montoya, JA; Ynaraja, E, 2001)
" We therefore measured lymphocyte free Mg2+ concentrations in patients with congestive cardiac failure treated with loop diuretics or a frusemide/amiloride mixture (Frumil) and compared them with control subjects."3.68Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics with and without amiloride. ( Brochwicz-Lewinski, MJ; Davies, JE; Garrido, MC; Ng, LL; Tan, LB, 1992)
"Two hundred and thirty-three patients (66 males and 167 females), aged 24 to 92 years, with congestive cardiac failure were entered into a long-term study to evaluate the efficacy and tolerability of treatment with a fixed dose combination tablet containing 1 mg bumetanide and 5 mg amiloride."3.68Bumetanide/amiloride ('Burinex A'): a new combined preparation for the control of patients with congestive cardiac failure. ( Hughes, IW; Lustman, F, 1990)
"The hemodynamic variations brought about by the single intravenous infection of 0,5 mg bumetanide have been studied in 7 patients with chronic ischemic heart disease and in 3 patients with non-obstructive hypertrophic cardiomyopathy, all of them in congestive heart failure."3.66[Hemodynamic changes produced by intravenous bumetanide in congestive heart failure]. ( Lomanto, B; Rossi, A; Ziacchi, V, 1981)
"The effect of bumetanide in infants with congenital heart disease presenting with cardiac failure was studied."3.65Bumetanide in heart failure in infancy. ( Lam, LK; Ward, OC, 1977)
"Forty patients with congestive heart failure or hypertensive heart disease were given long-term maintenance treatment with a combined bumetanide/slow-release potassium supplement preparation ('Burinex K')."3.65Patient tolerance of long-term diuretic/potassium supplement therapy. ( Singh, BB; Watt, DA, 1976)
"Heart failure is characterized by excess fluid accumulation, in both the vascular compartment and interstitial space, yet many heart failure patients have arterial underfilling because of low cardiac output, which may be aggravated by conventional diuretic treatment."2.87Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis. ( Boulton, DW; Greasley, PJ; Hallow, KM; Helmlinger, G; McMurray, JJV, 2018)
"It is recommended in severe congestive heart failure (HF)."2.71Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature. ( Galatius, S; Gustafsson, F; Hildebrandt, PR; Rosenberg, J, 2005)
" Eight hours after dosing began, we administered approximately 80 mEq sodium intravenously and examined its excretion over 4 hours."2.68Role of duration of diuretic effect in preventing sodium retention. ( Becker, PK; Brater, DC; Ferguson, JA; Gorski, JC; Rudy, DW; Sundblad, KJ, 1997)
"Mild congestive cardiac failure symptoms (raised jugular venous pressure, oedema and dyspnoea at rest and on effort) were controlled in 9/10 patients receiving frusemide/amiloride but two patients receiving bumetanide/potassium chloride still had mild oedema after 8 weeks."2.67An open, randomized comparative study of a low-strength frusemide/amiloride combination and bumetanide/potassium chloride in the treatment of mild congestive cardiac failure. ( Allman, S; Dalton, K; Finnamore, VP; Latta, D, 1990)
"In a random crossover study in general practice, sixty patients with heart failure were given one week's maintenance treatment with the recommended dosage of Burinex K or Lasix+K."2.64Patient acceptability of two diuretic/potassium supplement preparations. ( Bennion-Pedley, J; Donald, JF; Gould, CH; Lomas, DM; Postlethwaite, DL; Rivlin, R, 1976)
"Hypoalbuminemia is believed to decrease diuretic effectiveness and contribute to diuretic resistance that is observed in patients with nephrotic syndrome."1.39The effect of continuous infusion loop diuretics in patients with acute decompensated heart failure with hypoalbuminemia. ( Bleske, BE; Clark, MM; Dorsch, MP; Wu, AH, 2013)
"Treatment of congestive heart failure has changed dramatically during the past 20 years, but diuretic drugs remain an essential component."1.31Diuretic therapy and resistance in congestive heart failure. ( Ellison, DH, 2001)
"Patients with severe congestive heart failure (New York Heart Association [NYHA] functional classes III-IV) often can tolerate only low doses of angiotensin-converting enzyme (ACE) inhibitors because pronounced hypotension caused by additional ACE inhibitor increments may decrease renal perfusion."1.29Spironolactone in congestive heart failure refractory to high-dose loop diuretic and low-dose angiotensin-converting enzyme inhibitor. ( Donker, AJ; Nauta, JJ; van Vliet, AA; Verheugt, FW, 1993)
"03 L/kg) and the elimination half-life (13."1.28Pharmacokinetics and pharmacodynamics of bumetanide in neonates treated with extracorporeal membrane oxygenation. ( Fasules, JW; Kearns, GL; Taylor, BJ; Wells, TG, 1992)
"In advanced heart failure, mitral regurgitation increases the burden of the failing ventricle and decreases effective stroke volume."1.28Afterload reduction with vasodilators and diuretics decreases mitral regurgitation during upright exercise in advanced heart failure. ( Belil, D; Brunken, RC; Grover-McKay, M; Schelbert, HR; Schwaiger, M; Stevenson, LW; Tillisch, JH, 1990)
"Bumetanide2 is a new diuretic with a rapid onset and short duration of action."1.25Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema. ( Avery, GS; Brogden, RN; Speight, TM, 1975)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199037 (48.68)18.7374
1990's12 (15.79)18.2507
2000's10 (13.16)29.6817
2010's14 (18.42)24.3611
2020's3 (3.95)2.80

Authors

AuthorsStudies
Doggrell, SA1
Hansrivijit, P1
Techorueangwiwat, C1
Khanal, R1
Dimech, CT1
Thongprayoon, C1
Cheungpasitporn, W1
Girerd, N1
Aubry, M1
Lantelme, P1
Huttin, O1
Rossignol, P1
Hallow, KM1
Helmlinger, G1
Greasley, PJ1
McMurray, JJV1
Boulton, DW1
Täger, T1
Fröhlich, H1
Grundtvig, M1
Seiz, M1
Schellberg, D1
Goode, K1
Kazmi, S1
Hole, T1
Katus, HA1
Atar, D1
Cleland, JGF1
Agewall, S1
Clark, AL1
Frankenstein, L1
Verbrugge, FH3
Martens, P1
Ameloot, K1
Haemels, V1
Penders, J3
Dupont, M3
Tang, WHW1
Droogné, W2
Mullens, W3
Xiong, L1
Chinaeke, EE1
Lu, K1
Lenihan, DJ1
Merritt, TE1
Cox, ZL1
Bleske, BE1
Clark, MM1
Wu, AH1
Dorsch, MP1
Ng, TM1
Konopka, E1
Hyderi, AF1
Hshieh, S1
Tsuji, Y1
Kim, BJ1
Han, SY1
Phan, DH1
Jeng, AI1
Lou, M1
Elkayam, U1
Valente, MA1
Voors, AA2
Damman, K2
Van Veldhuisen, DJ1
Massie, BM1
O'Connor, CM1
Metra, M1
Ponikowski, P1
Teerlink, JR1
Cotter, G1
Davison, B1
Cleland, JG1
Givertz, MM2
Bloomfield, DM1
Fiuzat, M1
Dittrich, HC1
Hillege, HL1
Jacobs, S1
Waelbers, V1
Bossche, KV1
Bollen, H1
Geens, J1
Rega, F1
Burkhoff, D1
Meyns, B1
Nijst, P2
Tang, WH3
Shisler, D1
Austin, TM1
Delpire, E1
Sawyer, DB1
Pandey, AK1
Bertrand, PB1
Dens, J1
Verhaert, D1
Vandervoort, P1
Testani, JM2
Hanberg, JS2
Cheng, S1
Rao, V1
Onyebeke, C1
Laur, O1
Kula, A1
Chen, M1
Wilson, FP1
Darlington, A1
Bellumkonda, L2
Jacoby, D1
Parikh, CR1
Ter Maaten, JM1
Rao, VS1
Perry Wilson, F1
Assefa, M1
Sam Broughton, J1
D'Ambrosi, J1
Wilson Tang, WH1
Ellison, DH2
De Smedt, RH1
Jaarsma, T1
van den Broek, SA1
Haaijer-Ruskamp, FM1
Mielniczuk, LM1
Tsang, SW1
Desai, AS1
Nohria, A1
Lewis, EF1
Fang, JC1
Baughman, KL1
Stevenson, LW2
Lapsia, V1
Kazory, A1
Earl, G1
Davenport, J1
Narula, J1
Rosenberg, J1
Gustafsson, F1
Galatius, S1
Hildebrandt, PR1
Eshaghian, S1
Horwich, TB1
Fonarow, GC1
Chuen, MJ1
MacFadyen, RJ1
Mehta, RL1
Cantarovich, F1
Shaw, A1
Hoste, E1
Murray, P1
Sagar, S1
Sharma, BK1
Sharma, PL1
Wahi, PL1
Ward, A1
Heel, RC1
Brater, DC3
Day, B1
Burdette, A1
Anderson, S1
Misra, NP1
Jain, SC1
Maheshwari, J1
Gabriel, R1
Baylor, P1
Humair, L1
Ziacchi, V1
Rossi, A1
Lomanto, B1
Mauro, G1
Cantino, G1
Vigiani, L1
Pellerito, R1
Bertola, D1
Soragna, A1
Varricchio, M1
Spiezia, R1
Giugliano, D1
Torella, R1
Giannetti, G1
Brady, JA1
Rock, CL1
Horneffer, MR1
van Vliet, AA1
Donker, AJ1
Nauta, JJ1
Verheugt, FW1
Silke, B2
Andreasen, F1
Eriksen, UH1
Guul, SJ1
Nielsen, LP1
Bech, OM1
Diamant, B1
Kahr, O1
Bruun, P1
Hartling, OJ1
Hvidt, S1
Varriale, P1
Mossavi, A1
Ferguson, JA1
Sundblad, KJ1
Becker, PK1
Gorski, JC1
Rudy, DW1
Martinez-Alcaine, MA1
Ynaraja, E1
Corbera, JA1
Montoya, JA1
Taylor, I1
Watters, M1
Kubik, MM2
Bowers, E2
Underwood, PN3
Sigurd, B4
Olesen, KH2
Homeida, M1
Roberts, CJ1
Dombey, SL1
Ward, OC1
Lam, LK1
Vichi, FL1
de Oliveira, AC1
Fariña, FR1
Bernardes F, J1
Martins, JD1
Mazotti, L1
Michalsen, H1
Stokkeland, M1
Ditlefsen, EM1
Sangvik, K1
Kourouklis, C1
Christensen, O1
Augoustakis, D1
Bennion-Pedley, J1
Donald, JF1
Gould, CH1
Lomas, DM1
Postlethwaite, DL1
Rivlin, R1
Lawson, DH1
Boddy, K1
Gray, JM1
Mahaffey, M1
Mills, E1
Johansson, BW1
Hesse, B2
Bollerup, AC1
Valentin, N1
Olsen, KH1
Steiness, E1
Leth, A1
Hunter, KR1
Brogden, RN1
Speight, TM1
Avery, GS1
Singh, BB1
Watt, DA1
Wells, TG1
Fasules, JW1
Taylor, BJ1
Kearns, GL1
Ng, LL1
Garrido, MC1
Davies, JE1
Brochwicz-Lewinski, MJ1
Tan, LB1
Bourgain, C1
Bienvenu, T1
Crémieux, AC1
Delage, A1
Carbon, C1
Latta, D1
Finnamore, VP1
Dalton, K1
Allman, S2
Hughes, IW1
Lustman, F1
Brunken, RC1
Belil, D1
Grover-McKay, M1
Schwaiger, M1
Schelbert, HR1
Tillisch, JH1
Wilken-Jensen, C1
Ring-Larsen, H2
Henriksen, JH2
Clausen, J2
Pals, H2
Christensen, NJ2
Wilken, C1
Cook, JA1
Smith, DE1
Cornish, LA1
Tankanow, RM1
Nicklas, JM1
Hyneck, ML1
Chaudhuri, ML1
Catania, J1
Denisenko, BA1
Gol'dberg, GA1
Solov'eva, NN1
Bichan, NA1
Kashnikova, LG1
Verma, SP1
Reynolds, G1
Muller, P1
Frais, MA1
Taylor, SH1
Ramsay, F1
Crawford, RJ1
Bailey, R1
Martin, A1
Darlington, LG1
Pines, A1
Sreedharan, KS1
Nandi, AR1
Marsh, BT1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diamox/Aldactone to Increase the URinary Excretion of Sodium: an Investigational Study in Congestive Heart Failure[NCT01973335]Phase 434 participants (Actual)Interventional2013-11-30Completed
A Randomized, Open-label Study of Dapagliflozin in Patients With or Without Type 2 Diabetes Admitted With Acute Heart Failure[NCT04298229]Phase 3240 participants (Actual)Interventional2020-04-01Completed
Reverse Remodeling is Associated With Hemodynamic Improvement and Stabilization in Outpatients With Heart Failure With Reduced Ejection Fraction Treated With Sacubitril/Valsartan: an Echocardiographic Study[NCT04397302]652 participants (Actual)Observational [Patient Registry]2019-01-13Completed
Effect of Furosemide Withdraw in Stable Chronic Heart Failure Outpatients With Left Ventricular Dysfunction - the Brazilian Research Network on Heart Failure[NCT02689180]Phase 3230 participants (Anticipated)Interventional2015-05-31Recruiting
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs: Randomized Controlled Trial[NCT03989700]Phase 360 participants (Anticipated)Interventional2019-07-01Not yet recruiting
Efficacy of Aquapheresis in Patients Treated as Outpatients With Decompensated Heart Failure at a Veterans Hospital[NCT04572867]0 participants (Actual)Interventional2021-06-08Withdrawn (stopped due to Due to low enrollment, COVID-19 pandemic causing suspension of most outpatient elective procedures, and no protected research time, Dr. Gelzer Bell is unable to continue this study.)
High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure[NCT02429388]Phase 40 participants (Actual)Interventional2014-05-31Withdrawn (stopped due to Principal Investigator left institution prior to subjects being enrolled)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Acetazolamide Arm: Natriuresis 24 h

For the acetazolamide arm of the study, the primary end-point is total natriuresis after 24 h (mmol). To assess this, urine is collected for 24 h after the first administration of diuretics according to the study protocol and natriuresis is calculated as the total amount of diuresis (L) multiplied by the urinary sodium concentration (mmol/L). Subsequently, patients receiving acetazolamide and low-dose loop diuretics (both the groups with and without upfront spironolactone together) are compared to patients not receiving acetazolamide but high-dose loop diuretics instead (both the groups with or without upfront spironolactone together) (NCT01973335)
Timeframe: 24h

Interventionmmol (Mean)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone324
High-dose Loop Diuretics, Upfront Spironolactone300
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone211
High-dose Loop Diuretics, no Spironolactone190

NT-proBNP Change After 72 h

Relative NT-proBNP change (%) after 72 h compared to baseline. (NCT01973335)
Timeframe: 72h

Interventionpercentage change from baseline (Mean)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone-20
High-dose Loop Diuretics, Upfront Spironolactone-11
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone-3
High-dose Loop Diuretics, no Spironolactone-6

Number of Participants With Worsening Renal Function

Worsening renal function is defined as a rise in serum creatine >0.3 mg/dL or a >20% decrease in estimated glomerular filtration rate by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula compared to baseline at any time point before 72 h. Serum creatinine values are assessed at three consecutive mornings after study inclusion. (NCT01973335)
Timeframe: 72h

InterventionParticipants (Count of Participants)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone2
High-dose Loop Diuretics, Upfront Spironolactone0
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone3
High-dose Loop Diuretics, no Spironolactone0

Peak Plasma Aldosterone Concentration After 72 h

At three consecutive mornings after study inclusion, blood samples will be taken to assess plasma aldosterone levels. The highest value will constitute the peak plasma aldosterone concentration (ng/L). (NCT01973335)
Timeframe: 72h

Interventionng/L (Median)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone196
High-dose Loop Diuretics, Upfront Spironolactone234
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone302
High-dose Loop Diuretics, no Spironolactone204

Peak Plasma Renin Activity After 72 h

At three consecutive mornings after study inclusion, blood samples will be taken to assess plasma renin activity. The highest value will constitute the peak plasma renin activity (ng/mL/h). (NCT01973335)
Timeframe: 72h

Interventionµg/L/h (Median)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone3.8
High-dose Loop Diuretics, Upfront Spironolactone5.0
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone12.0
High-dose Loop Diuretics, no Spironolactone2.5

Persistent Renal Impairment

Persistent renal impairment is defined as a persistently elevated serum creatine >0.3mg/dL or >20% decrease in estimated glomerular filtration rate by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, above the baseline value of the patient and will be assessed on a scheduled follow-up appointment 4 weeks after hospital discharge. (NCT01973335)
Timeframe: 4 weeks after hospital discharge

InterventionParticipants (Count of Participants)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone3
High-dose Loop Diuretics, Upfront Spironolactone1
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone0
High-dose Loop Diuretics, no Spironolactone1

Spironolactone Arm: Incidence of Hypo- (Serum Potassium <3.5 mmol/L) or Hyperkalemia (Serum Potassium >5.0 mmol/L)

For the spironolactone arm of the study, the primary end-point is the incidence of either hypo- (serum potassium <3.5 mmol/L) or hyperkalemia (serum potassium >5.0 mmol/L) at any of 3 morning blood samples at consecutive days after randomization. Patients receiving upfront spironolactone (both the group receiving acetazolamide+low dose loop diuretics and the group receiving high-dose loop diuretic therapy) are compared with them receiving no spironolactone (both the group receiving acetazolamide+low dose loop diuretics and the group receiving high-dose loop diuretic therapy). (NCT01973335)
Timeframe: 72h

InterventionParticipants (Count of Participants)
Acetazolamide/Low-dose Loop Diuretics, Upfront Spironolactone1
High-dose Loop Diuretics, Upfront Spironolactone2
Acetazolamide/Low-dose Loop Diuretics, no Spironolactone5
High-dose Loop Diuretics, no Spironolactone2

Reviews

4 reviews available for bumetanide and Cardiac Failure

ArticleYear
Treatment outcomes of bumetanide continuous infusion: A systematic review and meta-analysis.
    Nephrology (Carlton, Vic.), 2020, Volume: 25, Issue:10

    Topics: Acute Kidney Injury; Bumetanide; Dose-Response Relationship, Drug; Duration of Therapy; Heart Failur

2020
Bumetanide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use.
    Drugs, 1984, Volume: 28, Issue:5

    Topics: Animals; Bumetanide; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Diuretics; Heart Failu

1984
Central hemodynamic effects of diuretic therapy in chronic heart failure.
    Cardiovascular drugs and therapy, 1993, Volume: 7 Suppl 1

    Topics: Bumetanide; Cardiac Output; Diuresis; Diuretics; Furosemide; Heart Failure; Hemodynamics; Humans; Mu

1993
Disposition and response to bumetanide and furosemide.
    The American journal of cardiology, 1986, Jan-24, Volume: 57, Issue:2

    Topics: Adult; Aged; Biological Availability; Bumetanide; Diuretics; Furosemide; Heart Failure; Humans; Kidn

1986

Trials

30 trials available for bumetanide and Cardiac Failure

ArticleYear
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:3

    Topics: Adult; Benzhydryl Compounds; Blood Volume; Bumetanide; Diuresis; Diuretics; Drug Combinations; Drug

2018
Acetazolamide to increase natriuresis in congestive heart failure at high risk for diuretic resistance.
    European journal of heart failure, 2019, Volume: 21, Issue:11

    Topics: Acetazolamide; Adult; Aged; Bumetanide; Dose-Response Relationship, Drug; Drug Resistance; Drug Ther

2019
Diuretic response in acute heart failure: clinical characteristics and prognostic significance.
    European heart journal, 2014, May-14, Volume: 35, Issue:19

    Topics: Acute Disease; Aged; Analysis of Variance; Atherosclerosis; Bumetanide; Diabetes Complications; Diur

2014
Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature.
    Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Blood Pressure; Body Weight; Bumetanide; Diuretics; Drug Therapy, Combinati

2005
A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Bumetanide; Clinical Trials as Topic; Diuretics; Doub

1984
Bumetanide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use.
    Drugs, 1984, Volume: 28, Issue:5

    Topics: Animals; Bumetanide; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Diuretics; Heart Failu

1984
Bumetanide and furosemide in heart failure.
    Kidney international, 1984, Volume: 26, Issue:2

    Topics: Absorption; Adult; Aged; Bumetanide; Diuretics; Dose-Response Relationship, Drug; Female; Furosemide

1984
Comparison of the chronic effects of bendrofluazide, bumetanide and frusemide on plasma biochemical variables.
    Postgraduate medical journal, 1981, Volume: 57, Issue:664

    Topics: Aged; Analysis of Variance; Bendroflumethiazide; Blood Chemical Analysis; Bumetanide; Clinical Trial

1981
A comparison of three diuretic regimens in heart failure.
    European journal of clinical investigation, 1993, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Blood Volume; Bumetanide; Circadian Rhythm; Diuretics;

1993
The benefit of low-dose dopamine during vigorous diuresis for congestive heart failure associated with renal insufficiency: does it protect renal function?
    Clinical cardiology, 1997, Volume: 20, Issue:7

    Topics: Acute Disease; Acute Kidney Injury; Aged; Aged, 80 and over; Bumetanide; Diuretics; Dopamine; Dose-R

1997
Role of duration of diuretic effect in preventing sodium retention.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:2

    Topics: Adult; Bumetanide; Cross-Over Studies; Diuretics; Female; Heart Failure; Humans; Infusions, Intraven

1997
Comparison of separate versus simultaneous administration of potassium supplement with the diuretic bumetanide.
    Current medical research and opinion, 1977, Volume: 5, Issue:3

    Topics: Aged; Bicarbonates; Bumetanide; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; H

1977
Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure.
    Acta medica Scandinavica, 1978, Volume: 203, Issue:1-2

    Topics: Bendroflumethiazide; Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Drug Evaluation; Dru

1978
A single dose comparison of piretanide and bumetanide in congestive cardiac failure.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:2

    Topics: Aged; Bumetanide; Calcium; Clinical Trials as Topic; Diuretics; Female; Heart Failure; Humans; Male;

1979
Longterm experience of the routine use of bumetanide.
    The British journal of clinical practice, 1976, Volume: 30, Issue:1

    Topics: Aged; Bumetanide; Clinical Trials as Topic; Coronary Disease; Diuretics; Female; Heart Failure; Huma

1976
[Bumetanide (Burinex) --furosemide (Lasix). A comparative study in congestive heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Sep-30, Volume: 96, Issue:27

    Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Drug Evaluation; Furosemide; Heart Failure; Humans

1976
Bumetanide in congestive heart failure.
    Current medical research and opinion, 1976, Volume: 4, Issue:6

    Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Electrolytes; Heart Failure; Humans

1976
Patient acceptability of two diuretic/potassium supplement preparations.
    The Journal of international medical research, 1976, Volume: 4, Issue:1

    Topics: Aged; Bumetanide; Clinical Trials as Topic; Deglutition; Delayed-Action Preparations; Diuretics; Dru

1976
[Bumetanide--a new potent diuretic for oral and intravenous use].
    Lakartidningen, 1975, Sep-10, Volume: 72, Issue:37

    Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Drug Evaluation; Furosemide; Heart Failure; Humans;

1975
Investigations with intravenous bumetanide.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 6

    Topics: Adolescent; Adult; Aged; Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Female; Glomerul

1975
Diuretic action of bumetanide in congestive heart failure.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 6

    Topics: Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Drug Evaluation; Glomerular Filtration Ra

1975
Evaluation of once-daily versus twice-daily bumetanide in heart failure.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 6

    Topics: Aged; Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Dose-Response Relationship, Drug; H

1975
An open, randomized comparative study of a low-strength frusemide/amiloride combination and bumetanide/potassium chloride in the treatment of mild congestive cardiac failure.
    The Journal of international medical research, 1990, Volume: 18 Suppl 2

    Topics: Adult; Amiloride; Blood Pressure; Bumetanide; Diuretics; Drug Combinations; Female; Furosemide; Hear

1990
[Effect of posture on the diuretic treatment of decompensated cirrhosis and heart failure].
    Ugeskrift for laeger, 1989, Jan-02, Volume: 151, Issue:1

    Topics: Adult; Aged; Bumetanide; Diuretics; Female; Heart Failure; Humans; Liver Cirrhosis, Alcoholic; Male;

1989
Diuretic treatment in decompensated cirrhosis and congestive heart failure: effect of posture.
    British medical journal (Clinical research ed.), 1986, May-24, Volume: 292, Issue:6532

    Topics: Adult; Aged; Aldosterone; Bumetanide; Diuretics; Female; Glomerular Filtration Rate; Heart Failure;

1986
Kinetics, dynamics, and bioavailability of bumetanide in healthy subjects and patients with congestive heart failure.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:5

    Topics: Administration, Oral; Adult; Aged; Biological Availability; Blood Proteins; Bumetanide; Diuretics; D

1988
A comparison of the effects of bumetanide (Burinex) and frusemide on carbohydrate metabolism in the elderly.
    The British journal of clinical practice, 1988, Volume: 42, Issue:10

    Topics: Aged; Aged, 80 and over; Blood Glucose; Bumetanide; Diuretics; Female; Furosemide; Glucose Tolerance

1988
[Clinical study of the effectiveness of a new Russian diuretic buphenox (bumetanide) in cardiac insufficiency].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:2

    Topics: Adult; Aged; Bumetanide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Heart Failure; Hu

1988
Immediate effects of bumetanide on systemic haemodynamics and left ventricular volume in acute and chronic heart failure.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:1

    Topics: Acute Disease; Adult; Aged; Bumetanide; Chronic Disease; Clinical Trials as Topic; Diuretics; Electr

1987
An open comparative study of two diuretic combinations, frusemide/amiloride ('Frumil') and bumetanide/potassium chloride ('Burinex' K), in the treatment of congestive cardiac failure in hospital out-patients.
    Current medical research and opinion, 1988, Volume: 10, Issue:10

    Topics: Aged; Aged, 80 and over; Ambulatory Care; Amiloride; Bumetanide; Diuretics; Drug Combinations; Femal

1988

Other Studies

43 other studies available for bumetanide and Cardiac Failure

ArticleYear
A new role for an old drug: acetazolamide in decompensated heart failure.
    Expert opinion on pharmacotherapy, 2023, Volume: 24, Issue:3

    Topics: Acetazolamide; Bumetanide; Diuretics; Heart Failure; Humans; Quality of Life; Treatment Outcome

2023
Intravenous Mineralocorticoid Receptor Antagonist Use in Acutely Decompensated Heart Failure with Diuretic Resistance.
    International heart journal, 2021, Jan-30, Volume: 62, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Bumetanide; Canrenoic Acid; Creatinine; Diures

2021
Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure - A multicenter propensity score matched analysis.
    International journal of cardiology, 2019, 08-15, Volume: 289

    Topics: Aged; Blood Pressure; Bumetanide; Cause of Death; Europe; Female; Follow-Up Studies; Furosemide; Hea

2019
Evaluation of Severe Myalgia Induced by Continuous-Infusion Bumetanide in Patients with Acute Heart Failure.
    Pharmacotherapy, 2019, Volume: 39, Issue:8

    Topics: Bumetanide; Diuretics; Electronic Health Records; Female; Furosemide; Heart Failure; Humans; Inciden

2019
The effect of continuous infusion loop diuretics in patients with acute decompensated heart failure with hypoalbuminemia.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:4

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Bumetanide; Creatinine; Diuretics;

2013
Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:4

    Topics: Acute Disease; Adult; Aged; Blood Urea Nitrogen; Bumetanide; Cohort Studies; Diuretics; Drug Therapy

2013
Evolution of renal function after partial and full mechanical support for chronic heart failure.
    The International journal of artificial organs, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Bumetanide; Creatinine; Diuretics; Female; Heart Failure; Heart-Assist Devices; Humans;

2014
Urinary composition during decongestive treatment in heart failure with reduced ejection fraction.
    Circulation. Heart failure, 2014, Volume: 7, Issue:5

    Topics: Administration, Oral; Aged; Biomarkers; Bumetanide; Chlorides; Diuretics; Dose-Response Relationship

2014
Syndrome of severe pain associated with a continuous bumetanide infusion.
    International journal of cardiology, 2014, Dec-15, Volume: 177, Issue:2

    Topics: Aged; Bumetanide; Diuretics; Female; Heart Failure; Humans; Hyperalgesia; Infusions, Intravenous; Mu

2014
Determinants and impact of the natriuretic response to diuretic therapy in heart failure with reduced ejection fraction and volume overload.
    Acta cardiologica, 2015, Volume: 70, Issue:3

    Topics: Aged; Bumetanide; Cohort Studies; Diuretics; Female; Heart Failure; Humans; Male; Natriuresis; Prosp

2015
Rapid and Highly Accurate Prediction of Poor Loop Diuretic Natriuretic Response in Patients With Heart Failure.
    Circulation. Heart failure, 2016, Volume: 9, Issue:1

    Topics: Acute Disease; Administration, Intravenous; Aged; Biomarkers; Bumetanide; Drug Monitoring; Drug Resi

2016
Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure.
    European journal of heart failure, 2017, Volume: 19, Issue:8

    Topics: Acute Disease; Administration, Intravenous; Biomarkers; Bumetanide; Dose-Response Relationship, Drug

2017
Decompensation of chronic heart failure associated with pregabalin in a 73-year-old patient with postherpetic neuralgia: a case report.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:2

    Topics: Aged; Anticonvulsants; Bumetanide; Chronic Disease; gamma-Aminobutyric Acid; Heart Failure; Herpes Z

2008
The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients.
    Journal of cardiac failure, 2008, Volume: 14, Issue:5

    Topics: Ambulatory Care; Ambulatory Care Facilities; Antihypertensive Agents; Bumetanide; Comorbidity; Diure

2008
The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients.
    Journal of cardiac failure, 2008, Volume: 14, Issue:5

    Topics: Ambulatory Care; Ambulatory Care Facilities; Antihypertensive Agents; Bumetanide; Comorbidity; Diure

2008
The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients.
    Journal of cardiac failure, 2008, Volume: 14, Issue:5

    Topics: Ambulatory Care; Ambulatory Care Facilities; Antihypertensive Agents; Bumetanide; Comorbidity; Diure

2008
The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients.
    Journal of cardiac failure, 2008, Volume: 14, Issue:5

    Topics: Ambulatory Care; Ambulatory Care Facilities; Antihypertensive Agents; Bumetanide; Comorbidity; Diure

2008
Loop diuretics for heart failure-associated hyponatremia.
    The American journal of medicine, 2010, Volume: 123, Issue:8

    Topics: Bumetanide; Female; Heart Failure; Humans; Hyponatremia; Middle Aged; Sodium; Sodium Potassium Chlor

2010
Furosemide challenge in patients with heart failure and adverse reactions to sulfa-containing diuretics.
    Annals of internal medicine, 2003, Feb-18, Volume: 138, Issue:4

    Topics: Aged; Bumetanide; Diuretics; Drug Hypersensitivity; Female; Furosemide; Heart Failure; Humans; Male

2003
Relation of loop diuretic dose to mortality in advanced heart failure.
    The American journal of cardiology, 2006, Jun-15, Volume: 97, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bumetanide; California; Creatinine; Diuretics; Dose-Resp

2006
Dose-dependent association between use of loop diuretics and mortality in advanced systolic heart failure.
    The American journal of cardiology, 2006, Nov-15, Volume: 98, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bumetanide; California; Creatinine; Diuretics; Dose-Resp

2006
Pharmacologic approaches for volume excess in acute kidney injury (AKI).
    The International journal of artificial organs, 2008, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Ascites; Bumetanide; Diuretics; Fluid Therapy; Furosemide; Heart Failure; Hepat

2008
Bumetanide in congestive cardiac failure.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:12

    Topics: Bumetanide; Diuresis; Diuretics; Heart Failure; Humans

1983
[Bumetanide in renal insufficiency].
    Schweizerische medizinische Wochenschrift, 1982, Feb-27, Volume: 112, Issue:9

    Topics: Aged; Bumetanide; Diuretics; Female; Heart Failure; Humans; Hypertension; Kidney Failure, Chronic; L

1982
[Hemodynamic changes produced by intravenous bumetanide in congestive heart failure].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:1

    Topics: Aged; Bumetanide; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged

1981
[Clinical evaluation of bumetanide in the diuretic treatment of heart failure and liver cirrhosis].
    La Clinica terapeutica, 1981, Mar-15, Volume: 96, Issue:5

    Topics: Adult; Aged; Bumetanide; Diuresis; Diuretics; Electrolytes; Ethacrynic Acid; Female; Furosemide; Hea

1981
[Clinical use of bumetanide].
    La Clinica terapeutica, 1981, Sep-30, Volume: 98, Issue:6

    Topics: Blood Pressure; Bumetanide; Diuresis; Diuretics; Edema; Electrolytes; Female; Heart Failure; Humans;

1981
[Clinical evaluation of bumetanide in congestive heart failure].
    Il Farmaco; edizione pratica, 1980, Volume: 35, Issue:7

    Topics: Adult; Aged; Bumetanide; Diuretics; Female; Heart Failure; Humans; Male; Middle Aged

1980
Thiamin status, diuretic medications, and the management of congestive heart failure.
    Journal of the American Dietetic Association, 1995, Volume: 95, Issue:5

    Topics: Adult; Aged; Bumetanide; Cross-Sectional Studies; Diet Records; Female; Food-Drug Interactions; Furo

1995
Spironolactone in congestive heart failure refractory to high-dose loop diuretic and low-dose angiotensin-converting enzyme inhibitor.
    The American journal of cardiology, 1993, Jan-21, Volume: 71, Issue:3

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Bumetanide; Drug Resistance; Drug

1993
Effect of short-term treatment with bumetanide, quinapril and low-sodium diet on dogs with moderate congestive heart failure.
    Australian veterinary journal, 2001, Volume: 79, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bumetanide; Diet, Sodium-Restricted; Diuretics; D

2001
Pulmonary oedema after ophthalmic regional anaesthesia in an unfasted patient undergoing elective surgery.
    Anaesthesia, 2001, Volume: 56, Issue:5

    Topics: Aged; Anesthesia, Conduction; Bumetanide; Diuretics; Fasting; Female; Heart Failure; Humans; Intubat

2001
Diuretic therapy and resistance in congestive heart failure.
    Cardiology, 2001, Volume: 96, Issue:3-4

    Topics: Benzothiadiazines; Bumetanide; Diuretics; Drug Resistance; Drug Synergism; Drug Therapy, Combination

2001
Diuretic therapy and resistance in congestive heart failure.
    Cardiology, 2001, Volume: 96, Issue:3-4

    Topics: Benzothiadiazines; Bumetanide; Diuretics; Drug Resistance; Drug Synergism; Drug Therapy, Combination

2001
Diuretic therapy and resistance in congestive heart failure.
    Cardiology, 2001, Volume: 96, Issue:3-4

    Topics: Benzothiadiazines; Bumetanide; Diuretics; Drug Resistance; Drug Synergism; Drug Therapy, Combination

2001
Diuretic therapy and resistance in congestive heart failure.
    Cardiology, 2001, Volume: 96, Issue:3-4

    Topics: Benzothiadiazines; Bumetanide; Diuretics; Drug Resistance; Drug Synergism; Drug Therapy, Combination

2001
The supra-additive natriuretic effect addition of theophylline ethylenediamine and bumetanide in congestive heart failure. Permutation trial tests in patients in long-term treatment with bumetanide.
    American heart journal, 1977, Volume: 94, Issue:2

    Topics: Adult; Bumetanide; Diuretics; Drug Therapy, Combination; Ethylenediamines; Heart Failure; Humans; Lo

1977
Bumetanide in heart failure in infancy.
    Archives of disease in childhood, 1977, Volume: 52, Issue:11

    Topics: Acute Disease; Bumetanide; Diuresis; Diuretics; Heart Defects, Congenital; Heart Failure; Humans; In

1977
[Bumetanide in the treatment of congestive heart failure and arterial hypertension].
    Arquivos brasileiros de cardiologia, 1978, Volume: 31, Issue:4

    Topics: Body Weight; Bumetanide; Diuresis; Diuretics; Drug Therapy, Combination; Heart Failure; Humans; Hype

1978
Potassium supplements in patients receiving long-term diuretics for oedema.
    The Quarterly journal of medicine, 1976, Volume: 45, Issue:179

    Topics: Bendroflumethiazide; Body Composition; Bumetanide; Diuretics; Edema, Cardiac; Female; Furosemide; He

1976
Bumetanide: A preliminary report of its pharmacological properties and therapeutic efficacy in oedema.
    Drugs, 1975, Volume: 9, Issue:1

    Topics: Animals; Ascites; Bumetanide; Diuresis; Dogs; Drug Incompatibility; Edema; Heart Failure; Humans; Ki

1975
Patient tolerance of long-term diuretic/potassium supplement therapy.
    Current medical research and opinion, 1976, Volume: 4, Issue:2

    Topics: Adult; Aged; Bumetanide; Diuretics; Drug Combinations; Female; Heart Diseases; Heart Failure; Humans

1976
Pharmacokinetics and pharmacodynamics of bumetanide in neonates treated with extracorporeal membrane oxygenation.
    The Journal of pediatrics, 1992, Volume: 121, Issue:6

    Topics: Analysis of Variance; Bumetanide; Combined Modality Therapy; Diuresis; Extracorporeal Membrane Oxyge

1992
Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics with and without amiloride.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:3

    Topics: Amiloride; Bumetanide; Cations, Divalent; Drug Therapy, Combination; Furosemide; Heart Failure; Huma

1992
[Bumetanide as replacement therapy in furosemide-induced vasculitis].
    Presse medicale (Paris, France : 1983), 1990, Oct-06, Volume: 19, Issue:32

    Topics: Aged; Bumetanide; Female; Furosemide; Heart Failure; Humans; Vasculitis, Leukocytoclastic, Cutaneous

1990
Bumetanide/amiloride ('Burinex A'): a new combined preparation for the control of patients with congestive cardiac failure.
    Current medical research and opinion, 1990, Volume: 12, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiloride; Bumetanide; Drug Administration Schedule; Drug Combinatio

1990
Afterload reduction with vasodilators and diuretics decreases mitral regurgitation during upright exercise in advanced heart failure.
    Journal of the American College of Cardiology, 1990, Volume: 15, Issue:1

    Topics: Bumetanide; Diuretics; Exercise; Female; Ferricyanides; Furosemide; Heart; Heart Failure; Humans; Ma

1990
Study to compare the relative hyperuricaemic effects of frusemide and bumetanide.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Aged; Bumetanide; Diuretics; Edema; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; M

1986
A clinical assessment of bumetanide in patients not responding to other diuretics.
    The British journal of clinical practice, 1974, Volume: 28, Issue:9

    Topics: Aged; Bumetanide; Diuretics; Edema; Electrolytes; Female; Heart Failure; Humans; Male; Middle Aged;

1974