bumetanide and Asthma studies

bumetanide and Asthma

bumetanide has been researched along with Asthma in 5 studies

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

Excerpt	Relevance	Reference
"A randomized, double-blind, placebo-controlled study was conducted to compare the effects of two chemically unrelated "loop" diuretics, furosemide (40 mg) and bumetanide (2 mg) on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate (AMP) in 12 subjects with asthma."	9.07	Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma. ( Church, MK; Holgate, ST; Polosa, R; Prosperini, G; Rajakulasingam, K, 1993)
" The provocative concentration causing a 20% fall in FEV1 (logPC20) was calculated by linear interpolation of log dose-response curves."	6.67	Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. ( Barnes, PJ; Chen-Worsdell, YM; Chung, KF; Fuller, RW; O'Connor, BJ, 1991)
"A randomized, double-blind, placebo-controlled study was conducted to compare the effects of two chemically unrelated "loop" diuretics, furosemide (40 mg) and bumetanide (2 mg) on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate (AMP) in 12 subjects with asthma."	5.07	Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma. ( Church, MK; Holgate, ST; Polosa, R; Prosperini, G; Rajakulasingam, K, 1993)
" The provocative concentration causing a 20% fall in FEV1 (logPC20) was calculated by linear interpolation of log dose-response curves."	2.67	Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. ( Barnes, PJ; Chen-Worsdell, YM; Chung, KF; Fuller, RW; O'Connor, BJ, 1991)

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

4 (80.00)

18.2507

2000's

1 (20.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Polosa, R	2
Rajakulasingam, K	2
Prosperini, G	2
Magrì, S	1
Mastruzzo, C	1
Holgate, ST	2
Church, MK	1
Danahay, H	1
Atherton, H	1
Jones, G	1
Bridges, RJ	1
Poll, CT	1
Chung, KF	2
Barnes, PJ	2
O'Connor, BJ	1
Chen-Worsdell, YM	1
Fuller, RW	1

Studies

Polosa, R

Rajakulasingam, K

Prosperini, G

Magrì, S

Mastruzzo, C

Holgate, ST

Church, MK

Danahay, H

Atherton, H

Jones, G

Bridges, RJ

Poll, CT

Chung, KF

Barnes, PJ

O'Connor, BJ

Chen-Worsdell, YM

Fuller, RW

Reviews

1 review available for bumetanide and Asthma

Article	Year
Loop diuretics and asthma. Pulmonary pharmacology, 1992, Volume: 5, Issue:1 Topics: Animals; Asthma; Bronchoconstriction; Bumetanide; Cough; Diuretics; Furosemide; Humans	1992

Article

Year

Loop diuretics and asthma.

Pulmonary pharmacology, 1992, Volume: 5, Issue:1

Topics: Animals; Asthma; Bronchoconstriction; Bumetanide; Cough; Diuretics; Furosemide; Humans

1992

Trials

3 trials available for bumetanide and Asthma

Article	Year
Inhaled loop diuretics and basal airway responsiveness in man: evidence of a role for cyclo-oxygenase products. The European respiratory journal, 1995, Volume: 8, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Adult; Aerosols; Asthma; Bronchial Hyperreactivity	1995
Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma. The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:2 Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation T	1993
Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. The American review of respiratory disease, 1991, Volume: 143, Issue:6 Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bro	1991

Article

Year

Inhaled loop diuretics and basal airway responsiveness in man: evidence of a role for cyclo-oxygenase products.

The European respiratory journal, 1995, Volume: 8, Issue:4

Topics: Administration, Inhalation; Administration, Oral; Adult; Aerosols; Asthma; Bronchial Hyperreactivity

1995

Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma.

The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:2

Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation T

1993

Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects.

The American review of respiratory disease, 1991, Volume: 143, Issue:6

Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bro

1991

Other Studies

1 other study available for bumetanide and Asthma

Article	Year
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Asthma; Body Fluids; Bronchi; Bumetanid	2002

Article

Year

Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells.

American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2

Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Asthma; Body Fluids; Bronchi; Bumetanid

2002