Page last updated: 2024-10-23

bumetanide and Aging

bumetanide has been researched along with Aging in 15 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Half-life and mean residence time decreased markedly in the first month of life (p < 0."2.68Analysis of the variability in the pharmacokinetics and pharmacodynamics of bumetanide in critically ill infants. ( Blumer, JL; Myers, CM; Sullivan, JE; Witte, MK; Yamashita, TS, 1996)
"An important contributor to cerebral edema formation is the Na-K-Cl cotransporter (NKCC)."1.36Expression of Na-K-Cl cotransporter and edema formation are age dependent after ischemic stroke. ( Akella, P; Benashski, SE; Liu, F; McCullough, LD; Xu, Y, 2010)
"Pretreatment with bumetanide (0."1.35Age- and dose-specific anticonvulsant action of bumetanide in immature rats. ( Mares, P, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's7 (46.67)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koyama, Y1
Andoh, T1
Kamiya, Y1
Morita, S1
Miyazaki, T1
Uchimoto, K1
Mihara, T1
Goto, T1
Tao, K1
Ichikawa, J1
Matsuki, N1
Ikegaya, Y1
Koyama, R1
Kelly, T1
Kafitz, KW1
Roderigo, C1
Rose, CR1
Mares, P1
Liu, F1
Akella, P1
Benashski, SE1
Xu, Y1
McCullough, LD1
Davidovic, M1
Trailov, D1
Milosevic, D1
Radosavljevic, B1
Milanovic, P1
Djurica, S1
Loncar-Stevanovic, H1
Stevic, R1
Oberbauer, R1
Krivanek, P1
Turnheim, K1
Johanson, CE2
Preston, JE2
Dyas, M1
Sullivan, JE1
Witte, MK1
Yamashita, TS1
Myers, CM1
Blumer, JL1
Cox, JP1
Gibbs, CL1
Grubb, BR1
Pace, AJ1
Lee, E1
Koller, BH1
Boucher, RC1
Ihrig, I1
Schönheit, C1
Häussner, W1
Bernhardt, I1
Seagrave, JC1
Curry, M1
Ramsey, RC1
Martinez, JR1
Günther, R1
Kersten, L1
Bräunlich, H1

Trials

3 trials available for bumetanide and Aging

ArticleYear
Pharmacokinetics and pharmacodynamics of the diuretic bumetanide in the elderly.
    Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aging; Biological Availability; Blood Urea Nitrogen; Bumetanide;

1995
Analysis of the variability in the pharmacokinetics and pharmacodynamics of bumetanide in critically ill infants.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:4

    Topics: Aging; Bumetanide; Critical Illness; Diuretics; Female; Heart Diseases; Humans; Infant; Infant, Newb

1996
Skeletal muscle resting metabolism in cold-acclimated rats: effect of age, noradrenaline and hyperosmolarity.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:6

    Topics: Acclimatization; Aging; Animals; Basal Metabolism; Body Temperature Regulation; Bumetanide; Cold Tem

1997

Other Studies

12 other studies available for bumetanide and Aging

ArticleYear
Bumetanide, an inhibitor of cation-chloride cotransporter isoform 1, inhibits γ-aminobutyric acidergic excitatory actions and enhances sedative actions of midazolam in neonatal rats.
    Anesthesiology, 2013, Volume: 119, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Bumetanide; CA3 Region, Hippocampal; Calcium; Calcium Signaling; C

2013
Experimental febrile seizures induce age-dependent structural plasticity and improve memory in mice.
    Neuroscience, 2016, Mar-24, Volume: 318

    Topics: Aging; Animals; Bumetanide; Disease Models, Animal; Fever; Hippocampus; Memory; Mice; Neurogenesis;

2016
Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity.
    Glia, 2009, Volume: 57, Issue:9

    Topics: Aging; Animals; Aspartic Acid; Astrocytes; Biological Transport; Bumetanide; Cells, Cultured; Centra

2009
Age- and dose-specific anticonvulsant action of bumetanide in immature rats.
    Physiological research, 2009, Volume: 58, Issue:6

    Topics: Age Factors; Aging; Animals; Anticonvulsants; Bumetanide; Disease Models, Animal; Dose-Response Rela

2009
Expression of Na-K-Cl cotransporter and edema formation are age dependent after ischemic stroke.
    Experimental neurology, 2010, Volume: 224, Issue:2

    Topics: Aging; Animals; Brain; Brain Edema; Bumetanide; Infarction, Middle Cerebral Artery; Ischemic Attack,

2010
Magnesium, aging, and the elderly patient.
    TheScientificWorldJournal, 2004, Jul-29, Volume: 4

    Topics: Aged; Aged, 80 and over; Aging; Autopsy; Bumetanide; Diuretics; Female; Furosemide; Humans; Longevit

2004
Potassium efflux from infant and adult rat choroid plexuses: effects of CSF anion substitution, N-ethylmaleimide and Cl transport inhibitors.
    Neuroscience letters, 1994, Mar-14, Volume: 169, Issue:1-2

    Topics: Aging; Animals; Anions; Benzoates; Bumetanide; Chlorides; Choroid Plexus; Ethylmaleimide; Female; Fu

1994
Development of chloride transport by the rat choroid plexus, in vitro.
    Brain research, 1993, Oct-08, Volume: 624, Issue:1-2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Aging; Animals; Biological Transpor

1993
Alterations in airway ion transport in NKCC1-deficient mice.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Bronchi; Bumetanide; Carrier Proteins; Elect

2001
Characterisation of the potassium influx in rat erythrocytes.
    General physiology and biophysics, 1992, Volume: 11, Issue:4

    Topics: Aging; Animals; Bumetanide; Chlorides; Erythrocyte Membrane; Erythrocytes; Fatty Acids; In Vitro Tec

1992
Intracellular pH changes induced by exposure to weak acids and bases in submandibular cells of early postnatal rats.
    Archives of oral biology, 1992, Volume: 37, Issue:9

    Topics: Acetylcholine; Aging; Amiloride; Ammonium Chloride; Animals; Bumetanide; Butyrates; Butyric Acid; Ce

1992
Natriuretic effectiveness of bumetanide in rats with immature kidney function.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 286, Issue:1

    Topics: Aging; Animals; Bumetanide; Diuresis; Diuretics; Dose-Response Relationship, Drug; Female; Natriures

1987