bumetanide has been researched along with Acute Lung Injury in 3 studies
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bumetanide is a potent loop diuretic that acts as an inhibitor of sodium-potassium-chloride cotransporter 2 (NKCC2) and its isoform NKCC1." | 5.48 | Bumetanide attenuates acute lung injury by suppressing macrophage activation. ( Huang, KL; Hung, CM; Peng, CK; Wu, CP, 2018) |
| "Moreover, hyperglycemia is known to induce NKCC1 expression via the activation of the serum-glucocorticoid kinase 1 (SGK1)-NKCC1 pathway." | 1.56 | Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1-NKCC1 Pathway. ( Huang, KL; Lan, CC; Peng, CK; Wu, CP, 2020) |
| "Bumetanide is a potent loop diuretic that acts as an inhibitor of sodium-potassium-chloride cotransporter 2 (NKCC2) and its isoform NKCC1." | 1.48 | Bumetanide attenuates acute lung injury by suppressing macrophage activation. ( Huang, KL; Hung, CM; Peng, CK; Wu, CP, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CP | 3 |
| Huang, KL | 3 |
| Peng, CK | 3 |
| Lan, CC | 1 |
| Hung, CM | 1 |
| Shen, CH | 1 |
| Lin, JY | 1 |
| Chang, YL | 1 |
| Wu, SY | 1 |
3 other studies available for bumetanide and Acute Lung Injury
| Article | Year |
|---|---|
Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1-NKCC1 Pathway.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bumetanide; Hyperglycemia; Immediate-Early Pr | 2020 |
Bumetanide attenuates acute lung injury by suppressing macrophage activation.
Topics: Acute Lung Injury; Animals; Bumetanide; Cell Size; Gene Expression Regulation; Lipopolysaccharides; | 2018 |
Inhibition of NKCC1 Modulates Alveolar Fluid Clearance and Inflammation in Ischemia-Reperfusion Lung Injury via TRAF6-Mediated Pathways.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Bumetanide; Cell Line; Disease Models, Ani | 2018 |