buformin and Obesity
buformin has been researched along with Obesity in 8 studies
Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)." | 7.72 | Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004) |
| "The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia." | 7.65 | Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975) |
| " We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)." | 3.72 | Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004) |
| " In Austria, the association of lactic acidosis with biguanide therapy has led to a cancellation of the registration of buformin and phenformin." | 3.66 | [Biguanides: reasons for withdrawal of drugs and remaining indications]. ( Bolzano, K, 1978) |
| "The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia." | 3.65 | Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ohara, S | 1 |
| Komatsu, R | 1 |
| Matsuyama, T | 1 |
| Lefebvre, P | 1 |
| Luyckx, A | 1 |
| Mosora, F | 1 |
| Lacroix, M | 1 |
| Pirnay, F | 1 |
| Bolzano, K | 1 |
| Schräpler, P | 2 |
| Schulz, E | 2 |
| Nijssen, J | 1 |
| Adlung, J | 2 |
| Sekso, M | 1 |
| Solter, M | 1 |
| Zjacić, V | 1 |
| Cabrijan, T | 1 |
| Aylwin, CG | 1 |
| López, G | 1 |
| García de los Riós, M | 1 |
| Vial, T | 1 |
| Pinto, JL | 1 |
| Ojeda, A | 1 |
| Orellana, JL | 1 |
| Blatniczky, L | 1 |
| Kautzky, L | 1 |
| Péter, F | 1 |
Other Studies
8 other studies available for buformin and Obesity
| Article | Year |
|---|---|
Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus.
Topics: Buformin; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Insulin | 2004 |
Oxidation of an exogenous glucose load using naturally labelled 13C-glucose. Effect of butylbiguanide therapy in obese mildly diabetic subjects.
Topics: Adult; Biguanides; Blood Glucose; Buformin; Carbon Dioxide; Carbon Isotopes; Diabetes Mellitus; Fatt | 1978 |
[Biguanides: reasons for withdrawal of drugs and remaining indications].
Topics: Acidosis; Austria; Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Legislation, Drug; Met | 1978 |
[Effect of butylbiguanide in retard form on the glucose resorption and lactate-pyruvate concentration in blood].
Topics: Adult; Aged; Biguanides; Buformin; Delayed-Action Preparations; Glucose; Humans; Lactates; Middle Ag | 1977 |
[Effect of Buformin retard in adipose patients with impaired glucose tolerance].
Topics: Adult; Aged; Biguanides; Blood Glucose; Buformin; Fatty Acids, Nonesterified; Glucose; Glycerol; Hum | 1975 |
Treatment of reactive hypoglycemia with buformin.
Topics: Adult; Biguanides; Blood Glucose; Buformin; Female; Glucose Tolerance Test; Humans; Hypoglycemia; In | 1975 |
[Failure of oral hypoglycemic agents: clinical experiences in 20 years' follow-up].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Weight; Buformin; Diabetes | 1988 |
[The effect of adebit on carbohydrate and insulin metabolism in childhood obesity].
Topics: Adolescent; Age Factors; Biguanides; Buformin; C-Peptide; Child; Child, Preschool; Humans; Infant; I | 1986 |