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buformin and Obesity

buformin has been researched along with Obesity in 8 studies

Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)."7.72Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004)
"The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia."7.65Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975)
" We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)."3.72Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004)
" In Austria, the association of lactic acidosis with biguanide therapy has led to a cancellation of the registration of buformin and phenformin."3.66[Biguanides: reasons for withdrawal of drugs and remaining indications]. ( Bolzano, K, 1978)
"The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia."3.65Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohara, S1
Komatsu, R1
Matsuyama, T1
Lefebvre, P1
Luyckx, A1
Mosora, F1
Lacroix, M1
Pirnay, F1
Bolzano, K1
Schräpler, P2
Schulz, E2
Nijssen, J1
Adlung, J2
Sekso, M1
Solter, M1
Zjacić, V1
Cabrijan, T1
Aylwin, CG1
López, G1
García de los Riós, M1
Vial, T1
Pinto, JL1
Ojeda, A1
Orellana, JL1
Blatniczky, L1
Kautzky, L1
Péter, F1

Other Studies

8 other studies available for buformin and Obesity

ArticleYear
Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus.
    Diabetes research and clinical practice, 2004, Volume: 66, Issue:2

    Topics: Buformin; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Insulin

2004
Oxidation of an exogenous glucose load using naturally labelled 13C-glucose. Effect of butylbiguanide therapy in obese mildly diabetic subjects.
    Diabetologia, 1978, Jan-14, Volume: 14, Issue:1

    Topics: Adult; Biguanides; Blood Glucose; Buformin; Carbon Dioxide; Carbon Isotopes; Diabetes Mellitus; Fatt

1978
[Biguanides: reasons for withdrawal of drugs and remaining indications].
    Acta medica Austriaca, 1978, Volume: 5, Issue:3

    Topics: Acidosis; Austria; Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Legislation, Drug; Met

1978
[Effect of butylbiguanide in retard form on the glucose resorption and lactate-pyruvate concentration in blood].
    Die Medizinische Welt, 1977, Mar-04, Volume: 28, Issue:9

    Topics: Adult; Aged; Biguanides; Buformin; Delayed-Action Preparations; Glucose; Humans; Lactates; Middle Ag

1977
[Effect of Buformin retard in adipose patients with impaired glucose tolerance].
    Die Medizinische Welt, 1975, Oct-17, Volume: 26, Issue:42

    Topics: Adult; Aged; Biguanides; Blood Glucose; Buformin; Fatty Acids, Nonesterified; Glucose; Glycerol; Hum

1975
Treatment of reactive hypoglycemia with buformin.
    The American journal of clinical nutrition, 1975, Volume: 28, Issue:11

    Topics: Adult; Biguanides; Blood Glucose; Buformin; Female; Glucose Tolerance Test; Humans; Hypoglycemia; In

1975
[Failure of oral hypoglycemic agents: clinical experiences in 20 years' follow-up].
    Revista medica de Chile, 1988, Volume: 116, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Weight; Buformin; Diabetes

1988
[The effect of adebit on carbohydrate and insulin metabolism in childhood obesity].
    Orvosi hetilap, 1986, Jun-08, Volume: 127, Issue:23

    Topics: Adolescent; Age Factors; Biguanides; Buformin; C-Peptide; Child; Child, Preschool; Humans; Infant; I

1986