buformin has been researched along with Metabolic Acidosis in 17 studies
Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A fatal case of lactic acidosis in a 84 year old diabetic woman taking buformin is reported." | 7.66 | Buformin concentrations in a case of fatal lactic acidosis. ( de Groot, G; Maes, RA; Sangster, B; van Heijst, AN; Verdonck, LF, 1981) |
| " All the patients had taken guanidine derivates (phenformine, buformine) because of diabetes mellitus." | 7.65 | [Lactic acidosis after administration of guanidine derivatives (buformine, phenformine) (author's transl)]. ( Butt, H; Reitinger, J, 1977) |
| "The paper presents an analysis of clinical symptoms, signs and laboratory data of 330 diabetic patients who developed lactic acidosis after having been treated with biguanides (phenformin, buformin, metformin)." | 4.75 | Lactic acidosis in biguanide-treated diabetics: a review of 330 cases. ( Eggstein, M; Luft, D; Schmülling, RM, 1978) |
| "A fatal case of lactic acidosis in a 84 year old diabetic woman taking buformin is reported." | 3.66 | Buformin concentrations in a case of fatal lactic acidosis. ( de Groot, G; Maes, RA; Sangster, B; van Heijst, AN; Verdonck, LF, 1981) |
| " In Austria, the association of lactic acidosis with biguanide therapy has led to a cancellation of the registration of buformin and phenformin." | 3.66 | [Biguanides: reasons for withdrawal of drugs and remaining indications]. ( Bolzano, K, 1978) |
| " All the patients had taken guanidine derivates (phenformine, buformine) because of diabetes mellitus." | 3.65 | [Lactic acidosis after administration of guanidine derivatives (buformine, phenformine) (author's transl)]. ( Butt, H; Reitinger, J, 1977) |
| "A survey of the literature leads to the conclusion that lactic acidosis should be considered as a side effect of therapy with biguanides." | 3.65 | [The importance of lactate acidosis as a side effect of biguanide therapy]. ( Förster, H, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verdonck, LF | 1 |
| Sangster, B | 1 |
| van Heijst, AN | 1 |
| de Groot, G | 1 |
| Maes, RA | 1 |
| Luft, D | 1 |
| Schmülling, RM | 1 |
| Eggstein, M | 1 |
| Offerhaus, L | 1 |
| Althoff, PH | 1 |
| Fassbinder, W | 1 |
| Neubauer, M | 1 |
| Koch, KM | 1 |
| Schöffling, K | 1 |
| Aro, A | 1 |
| Irsigler, K | 1 |
| Kritz, H | 1 |
| Regal, H | 1 |
| Foltin, E | 1 |
| Kimbel, KH | 1 |
| Deppermann, D | 1 |
| Heidland, A | 1 |
| Ritz, E | 1 |
| Hörl, W | 1 |
| Bolzano, K | 1 |
| Butt, H | 1 |
| Reitinger, J | 1 |
| Thimme, W | 1 |
| Buschmann, HJ | 1 |
| Dissmann, W | 1 |
| Amft, R | 1 |
| Buess, HJ | 1 |
| Mihatsch, MJ | 1 |
| Wunderlich, P | 1 |
| Berger, W | 2 |
| Förster, H | 1 |
| Mehnert-Aner, S | 1 |
| Mülly, K | 1 |
| Heierli, C | 1 |
| Ritz, R | 1 |
| Clavadetscher, P | 1 |
| Bischof, P | 1 |
| Wegmann, T | 1 |
| Ott, NT | 1 |
| Solé Violán, J | 1 |
| Martínez Chuecos, J | 1 |
| Molinero Somolinos, F | 1 |
| Marco Moreno, JM | 1 |
1 review available for buformin and Metabolic Acidosis
| Article | Year |
|---|---|
Lactic acidosis in biguanide-treated diabetics: a review of 330 cases.
Topics: Acidosis; Biguanides; Buformin; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemic Agen | 1978 |
1 trial available for buformin and Metabolic Acidosis
| Article | Year |
|---|---|
[The risk of lacticate acidosis: a comparison of the 3 biguanides in treatment of diabetics (authors' transl)].
Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Exercise Test; Female; Humans; Lactates; Male; Me | 1978 |
15 other studies available for buformin and Metabolic Acidosis
| Article | Year |
|---|---|
Buformin concentrations in a case of fatal lactic acidosis.
Topics: Acidosis; Aged; Biguanides; Buformin; Diabetes Complications; Female; Humans; Lactates; Tissue Distr | 1981 |
[Biguanides and lactate acidosis; consequences for registration advice].
Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Drug and Narcotic Control; Humans; Lactates; Neth | 1979 |
[Haemodialysis in the treatment of biguanide-induced lactate acidosis (author's transl)].
Topics: Acidosis; Acute Kidney Injury; Adult; Aged; Anuria; Biguanides; Buformin; Diabetes Mellitus; Female; | 1978 |
[Biguanides and lactic acidosis].
Topics: Acidosis; Biguanides; Buformin; Humans; Lactates; Metformin; Phenformin | 1978 |
[Biguanides].
Topics: Acidosis; Biguanides; Buformin; Humans; Metformin; Phenformin | 1978 |
[Lactic acidosis--a possible complication in buformin-treated diabetics (author's transl)].
Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Humans; Kinetics; Lactates; Pyruvates; Renal Dial | 1978 |
[Biguanides: reasons for withdrawal of drugs and remaining indications].
Topics: Acidosis; Austria; Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Legislation, Drug; Met | 1978 |
[Lactic acidosis after administration of guanidine derivatives (buformine, phenformine) (author's transl)].
Topics: Acidosis; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Female; Glomerular Filtration | 1977 |
[Lactic acidosis and biguanid therapy (author's transl)].
Topics: Acidosis; Aged; Anti-Bacterial Agents; Bicarbonates; Biguanides; Buffers; Buformin; Diabetes Mellitu | 1976 |
[Lactic acidosis in diabetes mellitus (author's transl)].
Topics: Acidosis; Aged; Alcoholism; Buformin; Diabetes Complications; Female; Heart Failure; Humans; Hyperte | 1976 |
[The importance of lactate acidosis as a side effect of biguanide therapy].
Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Drug Therapy, Combination; Ethanol; Humans; Kidne | 1976 |
[10 cases of lactic acidosis during biguanide therapy (buformin and phenformin)].
Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Glucagon; Humans; Lactates; Liver; Metformin; Phe | 1976 |
[Lactic acidosis after administration of buformine (author's transl)].
Topics: Acidosis; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Coma; Female; Humans | 1976 |
[Letter: Lactate acidosis].
Topics: Acidosis; Buformin; Humans; Lactates | 1976 |
[Overdose of biguanides].
Topics: Acidosis; Adolescent; Biguanides; Buformin; Female; Humans; Hypoglycemia; Lactates; Lactic Acid | 1985 |