Page last updated: 2024-10-23

buformin and Experimental Neoplasms

buformin has been researched along with Experimental Neoplasms in 3 studies

Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.

Research Excerpts

ExcerptRelevanceReference
"Chronic treatment of female rats with buformin (k mg/day per rat) is shown to decrease the body weight, to increase the average life span by 9% and to reduce the incidence of spontaneous tumors."3.66[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]. ( Anisimov, VN, 1980)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anisimov, VN3
Aleksandrov, VA1
Belous, NM2
Vasil'eva, IA1
Matson, VB1
Alexandrov, VA1
Vasilyeva, IA1
Mazon, VB1

Other Studies

3 other studies available for buformin and Experimental Neoplasms

ArticleYear
[Inhibition of the transplacental blastomogenic effect of N-nitrosomethylurea in rats by buformin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:7

    Topics: Animals; Antineoplastic Agents; Biguanides; Blood Glucose; Buformin; Castration; Cholesterol; Female

1980
[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats].
    Voprosy onkologii, 1980, Volume: 26, Issue:6

    Topics: Animals; Biguanides; Body Weight; Buformin; Estrus; Female; Longevity; Neoplasms, Experimental; Phen

1980
The inhibition of the transplacental blastomogenic effect of nitrosomethylurea by postnatal administration of buformin to rats.
    Carcinogenesis, 1980, Volume: 1, Issue:12

    Topics: Animals; Buformin; Cholesterol; Dietary Carbohydrates; Diethylstilbestrol; Energy Metabolism; Female

1980