buformin has been researched along with Diabetes Mellitus, Adult-Onset in 10 studies
Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)." | 7.72 | Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004) |
| " We have investigated the short-term effect of buformin on insulin sensitivity, solved tumor necrosis factor receptors (sTNFRs), and serum lipids in overweight subjects with type 2 diabetes mellitus (DM)." | 3.72 | Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus. ( Komatsu, R; Matsuyama, T; Ohara, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kitamura, R | 1 |
| Tanaka, Y | 1 |
| Montero Alonso, M | 1 |
| Salvador Cervelló, G | 1 |
| Perelló Roso, A | 1 |
| Roig Osca, MA | 1 |
| Ogawa, S | 1 |
| Takeuchi, K | 1 |
| Ito, S | 1 |
| Krishnamurthy, M | 1 |
| Sahouria, JJ | 1 |
| Desai, R | 1 |
| Caguiat, J | 1 |
| Ohara, S | 1 |
| Komatsu, R | 1 |
| Matsuyama, T | 1 |
| Matsuura, T | 1 |
| Miyao, M | 1 |
| Mizuno, Y | 1 |
| Perusicová, J | 1 |
| Skrha, J | 1 |
| Hodinár, A | 1 |
| Bernovská, A | 1 |
| Cacáková, V | 1 |
| Richtrová, A | 1 |
| Mori, K | 1 |
| Nakamura, J | 1 |
| Koh, N | 1 |
| Sakakibara, F | 1 |
| Hamada, Y | 1 |
| Hara, T | 1 |
| Komori, T | 1 |
| Nakashima, E | 1 |
| Naruse, K | 1 |
| Takeuchi, N | 1 |
| Hotta, N | 1 |
| Kawaji, K | 1 |
| Fujita, Y | 1 |
| Yajima, Y | 1 |
| Shirataka, M | 1 |
| Kubo, H | 1 |
| Aylwin, CG | 1 |
| López, G | 1 |
| García de los Riós, M | 1 |
| Vial, T | 1 |
| Pinto, JL | 1 |
| Ojeda, A | 1 |
| Orellana, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study of PPAR-Gamma Agonist-Rosiglitazone for Determining Cardiac Adverse Effects in Type 2 Diabetic Patients[NCT00300911] | Phase 4 | 45 participants | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for buformin and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
[Clinical usefulness of treatment with biguanide and insulin].
Topics: Biguanides; Buformin; Clinical Trials as Topic; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug | 2002 |
[A case of lactic acidosis caused by buformin in an oldest elderly diabetic patient].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Buformin; Diabetes Mellitus, Type 2; Humans; Hypoglycemic | 2005 |
1 trial available for buformin and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Plasma BNP levels in the treatment of type 2 diabetes with pioglitazone.
Topics: Aged; Atrial Natriuretic Factor; Body Mass Index; Buformin; Diabetes Mellitus, Type 2; Female; Glyca | 2003 |
7 other studies available for buformin and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
[Lactic acidosis associated with buformine use].
Topics: Acidosis, Lactic; Aged; Buformin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents | 2003 |
Buformin-induced lactic acidosis--a symptom of modern healthcare malady.
Topics: Acidosis, Lactic; Aged; Buformin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents | 2004 |
Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus.
Topics: Buformin; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Insulin | 2004 |
[Levels of lactic acid in type II diabetics treated with buformin].
Topics: Adult; Aged; Buformin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Lactates; Mal | 1996 |
Increased alanine uptake and lipid synthesis from alanine in isolated hepatocytes of Wistar-Kyoto fatty rats: an inhibitory effect of biguanides.
Topics: Aging; Alanine; Animals; Body Weight; Buformin; Cells, Cultured; Diabetes Mellitus, Experimental; Di | 1997 |
Usefulness of anaerobic threshold in estimating intensity of exercise for diabetics.
Topics: Adult; Anaerobiosis; Blood Glucose; Buformin; Diabetes Mellitus, Type 2; Exercise; Female; Glucagon; | 1989 |
[Failure of oral hypoglycemic agents: clinical experiences in 20 years' follow-up].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Weight; Buformin; Diabetes | 1988 |