buformin has been researched along with Breast Neoplasms in 2 studies
Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.
Breast Neoplasms: Tumors or cancer of the human BREAST.
Excerpt | Relevance | Reference |
---|---|---|
"MTT, cell cycle, clonogenic/CFC, ALDEFLUOR, tumorsphere, and Western blot analyses were used to determine the effects of buformin on cell growth, stem cell populations, stem cell-like properties, and signaling pathways in SKBR3 and BT474 erbB-2-overexpressing breast cancer cell lines." | 7.85 | Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice. ( Howard, EW; Ma, Z; Parris, AB; Yang, X; Zhao, M; Zhao, Q, 2017) |
"MTT, cell cycle, clonogenic/CFC, ALDEFLUOR, tumorsphere, and Western blot analyses were used to determine the effects of buformin on cell growth, stem cell populations, stem cell-like properties, and signaling pathways in SKBR3 and BT474 erbB-2-overexpressing breast cancer cell lines." | 3.85 | Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice. ( Howard, EW; Ma, Z; Parris, AB; Yang, X; Zhao, M; Zhao, Q, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Parris, AB | 1 |
Zhao, Q | 1 |
Howard, EW | 1 |
Zhao, M | 1 |
Ma, Z | 1 |
Yang, X | 1 |
Dil'man, VM | 1 |
Bershteĭn, LM | 1 |
Tsyrlina, EV | 1 |
Bobrov, IuF | 1 |
Kovaleva, IG | 1 |
2 other studies available for buformin and Breast Neoplasms
Article | Year |
---|---|
Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Buformin; Cell Line, Tumor; Cell Proliferation; Ce | 2017 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |