Page last updated: 2024-10-23

buformin and Breast Neoplasms

buformin has been researched along with Breast Neoplasms in 2 studies

Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"MTT, cell cycle, clonogenic/CFC, ALDEFLUOR, tumorsphere, and Western blot analyses were used to determine the effects of buformin on cell growth, stem cell populations, stem cell-like properties, and signaling pathways in SKBR3 and BT474 erbB-2-overexpressing breast cancer cell lines."7.85Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice. ( Howard, EW; Ma, Z; Parris, AB; Yang, X; Zhao, M; Zhao, Q, 2017)
"MTT, cell cycle, clonogenic/CFC, ALDEFLUOR, tumorsphere, and Western blot analyses were used to determine the effects of buformin on cell growth, stem cell populations, stem cell-like properties, and signaling pathways in SKBR3 and BT474 erbB-2-overexpressing breast cancer cell lines."3.85Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice. ( Howard, EW; Ma, Z; Parris, AB; Yang, X; Zhao, M; Zhao, Q, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parris, AB1
Zhao, Q1
Howard, EW1
Zhao, M1
Ma, Z1
Yang, X1
Dil'man, VM1
Bershteĭn, LM1
Tsyrlina, EV1
Bobrov, IuF1
Kovaleva, IG1

Other Studies

2 other studies available for buformin and Breast Neoplasms

ArticleYear
Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice.
    Journal of experimental & clinical cancer research : CR, 2017, 02-13, Volume: 36, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Buformin; Cell Line, Tumor; Cell Proliferation; Ce

2017
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
    Voprosy onkologii, 1975, Volume: 21, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C

1975