buformin has been researched along with Acidosis, Lactic in 11 studies
Buformin: An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.
buformin : A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect.
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 7.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| "As a class, the biguanides induce lactic acidosis, a hallmark of mitochondrial impairment." | 3.74 | Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. ( Billis, PA; Dykens, JA; Jamieson, J; Marroquin, L; Nadanaciva, S; Will, Y, 2008) |
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 3.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dykens, JA | 1 |
| Jamieson, J | 1 |
| Marroquin, L | 1 |
| Nadanaciva, S | 1 |
| Billis, PA | 1 |
| Will, Y | 1 |
| Montero Alonso, M | 1 |
| Salvador Cervelló, G | 1 |
| Perelló Roso, A | 1 |
| Roig Osca, MA | 1 |
| Krishnamurthy, M | 1 |
| Sahouria, JJ | 1 |
| Desai, R | 1 |
| Caguiat, J | 1 |
| Matsuura, T | 1 |
| Miyao, M | 1 |
| Mizuno, Y | 1 |
| Martínez Laso, A | 1 |
| Yano, A | 1 |
| Kubota, M | 1 |
| Iguchi, K | 1 |
| Usui, S | 1 |
| Hirano, K | 1 |
| Blasco Navalpotro, MA | 1 |
| Zaragoza Crespo, R | 1 |
| Olivares Toledo, D | 1 |
| Alamán Laguarda, G | 1 |
| Rojas Hidalgo, E | 1 |
| Ros, P | 1 |
| Lorente, JA | 1 |
| León, M | 1 |
| Landín, L | 1 |
| García de los Ríos, M | 1 |
| Huidobro, F | 1 |
| Videla, C | 1 |
| Hernández, G | 1 |
| Torres, H | 1 |
| Jimenez, R | 1 |
| Pérez, H | 1 |
| Díaz, RA | 1 |
2 reviews available for buformin and Acidosis, Lactic
| Article | Year |
|---|---|
[A case of lactic acidosis caused by buformin in an oldest elderly diabetic patient].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Buformin; Diabetes Mellitus, Type 2; Humans; Hypoglycemic | 2005 |
[Antidiabetic biguanides and lactic acidosis].
Topics: Acidosis, Lactic; Biguanides; Buformin; Diabetes Mellitus; Humans; Hypoglycemic Agents; Models, Biol | 1997 |
9 other studies available for buformin and Acidosis, Lactic
| Article | Year |
|---|---|
Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro.
Topics: Acidosis, Lactic; Animals; Blood Glucose; Buformin; Cell Line; Cell Respiration; Cell Survival; Cult | 2008 |
[Lactic acidosis associated with buformine use].
Topics: Acidosis, Lactic; Aged; Buformin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents | 2003 |
Buformin-induced lactic acidosis--a symptom of modern healthcare malady.
Topics: Acidosis, Lactic; Aged; Buformin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents | 2004 |
[A new case of lactic acidosis caused by buformin].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Buformin; Female; Humans; Hypoglycemic Agents | 2005 |
Buformin suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase.
Topics: Acidosis, Lactic; Adenosine Triphosphate; Blotting, Western; Buformin; Cell Line; DNA, Complementary | 2006 |
[Lactic acidosis and buformin].
Topics: Acidosis, Lactic; Aged; Buformin; Female; Humans; Hypoglycemic Agents | 1996 |
[Lactic acidosis associated with the use of biguanides].
Topics: Acidosis, Lactic; Aged; Buformin; Female; Humans | 1991 |
[Lactic acidosis in diabetic patients associated with buformin].
Topics: Acidosis, Lactic; Buformin; Diabetes Mellitus; Diabetic Ketoacidosis | 1989 |
[Lactic acidosis in diabetic patients associated with buformin].
Topics: Acidosis, Lactic; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Angiopathies | 1989 |