buflomedil has been researched along with Arterial Occlusive Diseases in 40 studies
buflomedil: RN given refers to parent cpd; synonym LL 1656 refers to HCl; structure
Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Buflomedil induced an increase of the same order of magnitude in plasma levels of adenosine and adenine nucleotides." | 2.68 | Increase in plasma levels of adenosine and adenine nucleotides after intravenous infusion of buflomedil in humans. ( Capecchi, PL; Chiavetta, M; De Lalla, A; Di Perri, T; Laghi Pasini, F; Sensi, S; Sodi, N; Volpi, L, 1995) |
| " and then orally, at a dosage of 600 mg/day." | 1.27 | Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV. ( Briguglio, E; Briguglio, F; Di Marco, V; Intilisano, A; Materia, G; Swat, M, 1986) |
| "Treatment with buflomedil for 3 months led to a significant improvement in signs and symptoms in all four clinical stages." | 1.27 | [Epidemiologic study of peripheral obstructive arteriopathies: clinical effects of treatment with buflomedil chlorhydrate (Loftyl). Processing of data furnished by a polycenter study]. ( , 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (82.50) | 18.7374 |
| 1990's | 6 (15.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paoletti, V | 1 |
| Mammarella, A | 1 |
| Alessandrini, A | 1 |
| Barlattani, M | 1 |
| Trübestein, G | 4 |
| Balzer, K | 2 |
| Bisler, H | 2 |
| Klüken, N | 2 |
| Muller-Wiefel, H | 2 |
| Unkel, B | 2 |
| Mahfoud, Y | 2 |
| Ziegler, W | 2 |
| Marshall, M | 1 |
| Sunder-Plassmann, L | 3 |
| Gandolfo, AM | 1 |
| Utz, C | 1 |
| Tallarida, G | 1 |
| Baldoni, F | 1 |
| Peruzzi, G | 1 |
| Raimondi, G | 1 |
| Grimaldi, I | 1 |
| Visigalli, G | 1 |
| Gristina, S | 1 |
| Massaro, M | 1 |
| De Martinis, L | 1 |
| Sangiorgi, M | 1 |
| Forconi, S | 2 |
| Pieragalli, D | 1 |
| Acciavatti, A | 2 |
| Del Bigo, C | 2 |
| Galigani, C | 1 |
| Ralli, L | 1 |
| Guerrini, M | 2 |
| Di Perri, T | 3 |
| Lemke, R | 1 |
| Klaus, D | 1 |
| Trübestein, R | 2 |
| Duong, QD | 1 |
| Perego, MA | 1 |
| Sergio, G | 1 |
| Espureo, M | 1 |
| Francisci, A | 1 |
| Artale, F | 1 |
| Materazzi, M | 1 |
| Rossi, C | 1 |
| Racenberg, J | 1 |
| Intaglietta, M | 1 |
| Messmer, K | 2 |
| Balas, P | 1 |
| Pagratis, N | 1 |
| Becker, HM | 1 |
| Tischler, R | 1 |
| Decrinis, M | 1 |
| Skursky-Roller, R | 1 |
| Capecchi, PL | 1 |
| Laghi Pasini, F | 1 |
| Sodi, N | 1 |
| Chiavetta, M | 1 |
| Sensi, S | 1 |
| De Lalla, A | 1 |
| Volpi, L | 1 |
| Marci, M | 1 |
| Albiani, B | 1 |
| Ricci, M | 1 |
| Russo, F | 1 |
| Joffre, F | 1 |
| Meites, G | 1 |
| Rousseau, H | 1 |
| Staffin, C | 1 |
| Allaert, FA | 1 |
| Pelat, P | 1 |
| Van den Brande, P | 1 |
| Maurel, A | 1 |
| Labs, KH | 1 |
| Eichlisberger, R | 1 |
| Jeanneret, C | 1 |
| Frauchiger, B | 1 |
| Aschwanden, M | 1 |
| Jäger, KA | 1 |
| Andreozzi, GM | 2 |
| Lepore, R | 2 |
| Ludwig, M | 1 |
| Mannarino, E | 1 |
| Pasqualini, L | 1 |
| Maragoni, G | 1 |
| Orlandi, U | 1 |
| Abate, S | 1 |
| Ferulano, GP | 1 |
| Vanni, L | 1 |
| Dilillo, S | 1 |
| Picilli, M | 1 |
| D'Alessio, E | 1 |
| Coglitore, S | 1 |
| Manganaro, A | 1 |
| Barbera, MC | 1 |
| Cento, D | 1 |
| Buda, D | 1 |
| Arrigo, F | 1 |
| Consolo, F | 1 |
| Dall'Antonia, F | 1 |
| Perbellini, A | 1 |
| Adami, CA | 1 |
| Dal Cortivo, G | 1 |
| Bucci, S | 1 |
| Licata, G | 1 |
| Parrinello, G | 1 |
| Scaglione, R | 1 |
| Indovina, A | 1 |
| Pinto, A | 2 |
| Capuana, G | 1 |
| Mazzola, G | 1 |
| Briguglio, F | 2 |
| Di Marco, V | 2 |
| Circosta, C | 1 |
| Padovano, I | 1 |
| Ragusa, S | 1 |
| Saija, A | 1 |
| Briguglio, E | 2 |
| Longo, FN | 1 |
| Potortì, F | 1 |
| Urbano, O | 1 |
| Perroni, GB | 1 |
| Visconti, W | 1 |
| Grillo, N | 1 |
| Frausini, G | 1 |
| Rotatori, P | 1 |
| Gaggi, S | 1 |
| Barone, A | 1 |
| Pupita, F | 1 |
| Romanò, M | 1 |
| Spinelli, A | 1 |
| Muzio, L | 1 |
| Cazzani, E | 1 |
| Baldini, MR | 1 |
| Lucisano, V | 1 |
| Margheriti, R | 1 |
| Matone, P | 1 |
| Morrieri, C | 1 |
| Rugolo, A | 1 |
| Corsi, V | 1 |
| Allegra, C | 1 |
| Avellone, G | 1 |
| Cospite, M | 1 |
| Del Guercio, R | 1 |
| Nuzzaci, G | 1 |
| Romeo, S | 1 |
| Swat, M | 1 |
| Materia, G | 1 |
| Intilisano, A | 1 |
| Heidrich, H | 1 |
| Dorigo, B | 1 |
| Raspanti, D | 1 |
| Trapani, M | 1 |
| Albanese, B | 1 |
| Cameli, AM | 1 |
| Digiesi, V | 1 |
| Mozzi, E | 1 |
| Chiurazzi, D | 1 |
| Spinola, A | 1 |
| Annoni, F | 1 |
| Germiniani, R | 1 |
1 review available for buflomedil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Treatment of chronic obliterative arteriopathy of the legs in the second Fontaine's stage. Personal experience with a buflomedil-pentoxifylline-defibrotide combination].
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Drug Therapy, Combination; Fe | 1995 |
12 trials available for buflomedil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Comparative study of various schedules of buflomedil treatment in peripheral arterial insufficiency of the lower limbs. Evaluation of its therapeutic efficacy].
Topics: Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Drug Administration Schedule; Fe | 1984 |
Buflomedil in arterial occlusive disease: results of a controlled multicenter study.
Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Hu | 1984 |
[Buflomedil in arterial occlusive disease. Results of a controlled study].
Topics: Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Femoral Ar | 1982 |
Comparative evaluation of the effectiveness of buflomedil and pentoxifylline in patients with arterial occlusive disease.
Topics: Adult; Aged; Analysis of Variance; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Bli | 1981 |
Increase in plasma levels of adenosine and adenine nucleotides after intravenous infusion of buflomedil in humans.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphospha | 1995 |
[Effect of buflomedil perfusion on peripheral tissue oxygenation during transluminal angioplasty in patients with advanced arteriopathy of the lower limbs].
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Arterial Occlusive Diseases; Blood Gas Monitoring, Tr | 1994 |
A placebo-controlled study of the effects of intravenous Buflomedil on foot skin microcirculation in patients with severe intermittent claudication.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Dose-Response Relationship, D | 1998 |
[Action and tolerability of delayed-action buflomedil in obliterating arteriopathies of the lower limbs. A multicenter study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Delayed-Action Preparations | 1990 |
[Bencyclane in stage II arterial occlusive disease. Results of a controlled study].
Topics: Aged; Arterial Occlusive Diseases; Bencyclane; Cycloheptanes; Double-Blind Method; Female; Humans; I | 1989 |
[Effects of buflomedil on peripheral arteriopathies. An open clinical study].
Topics: Administration, Oral; Adolescent; Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic | 1988 |
[Multicenter study on the therapeutic activity of buflomedil chlorhydrate in obliterative arteriopathies of the legs].
Topics: Arterial Occlusive Diseases; Blood Volume; Clinical Trials as Topic; Female; Humans; Leg; Male; Pyrr | 1986 |
[Vasoactive drugs in peripheral arterial perfusion disorders. Problems, principles and results of the determination of therapeutic efficacy].
Topics: Arterial Occlusive Diseases; Cardiovascular Agents; Cinnarizine; Clinical Trials as Topic; Dihydroer | 1985 |
27 other studies available for buflomedil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Arterio-vascular diseases. New trends in diagnosis and therapy].
Topics: Arterial Occlusive Diseases; Humans; Intermittent Claudication; Pyrrolidines; Vasodilator Agents | 1983 |
[Effectiveness of buflomedil in arterial occlusive disease. Modification of transcutaneous oxygen pressure in a placebo-controlled double-blind study].
Topics: Arterial Occlusive Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Leg; Oxy | 1984 |
[Effects of the administration of buflomedil-hydrochloride on the arterial circulation of the legs in patients with obliterative arteriopathies].
Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Drug Evaluation; Female; Humans; Leg; Male; Middl | 1983 |
Positive effect of oral buflomedil on exercise-induced haemorheological damage and on claudication distance in peripheral obliterative arterial disease patients.
Topics: Administration, Oral; Arterial Occlusive Diseases; Blood Viscosity; Female; Humans; Hydrogen-Ion Con | 1984 |
[Acute affect of buflomedil hydrochloride (bufedil) on transcutaneously measured oxygen pressures in patients with peripheral arterial occlusive disease].
Topics: Arterial Occlusive Diseases; Humans; Oxygen; Pyrrolidines; Vasodilator Agents | 1984 |
Haemodynamic and haemorheological effects of buflomedil in patients with peripheral occlusive arterial disease.
Topics: Arterial Occlusive Diseases; Blood Circulation; Blood Pressure; Blood Viscosity; Erythrocytes; Femal | 1982 |
Protective effects of buflomedil against exercise-induced reductions in regional erythrocyte deformability of patients with peripheral arterial disease.
Topics: Arterial Occlusive Diseases; Erythrocytes; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; | 1982 |
[Effect of the vasoactive drug buflomedil in arterial occlusive disease].
Topics: Animals; Arterial Occlusive Diseases; Blood Viscosity; Collateral Circulation; Dogs; Hemodynamics; H | 1982 |
[Improved microcirculation and collateral circulation in arterial occlusive diseases of the lower extremity].
Topics: Animals; Arterial Occlusive Diseases; Collateral Circulation; Dogs; Hemodilution; Hindlimb; Intermit | 1981 |
Experience with buflomedil in peripheral arterial occlusive disease.
Topics: Adult; Aged; Ankle; Arterial Occlusive Diseases; Female; Humans; Hyperemia; Leg; Male; Middle Aged; | 1981 |
Tissue pO2 and transcutaneous pO2 as guidelines in experimental and clinical drug evaluation.
Topics: Animals; Arterial Occlusive Diseases; Arteriosclerosis; Chronic Disease; Collateral Circulation; Dog | 1981 |
[Can vasomotion be modified by vasoactive substances or hemodilution?].
Topics: Alprostadil; Arterial Occlusive Diseases; Blood Flow Velocity; Capillaries; Combined Modality Therap | 1994 |
Assessment of collateral perfusion: a pharmacodynamic study with buflomedil hydrochloride.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Collateral Circulation; Female; Femoral | 2000 |
Effect of buflomedil chlorhydrate on local oxygen delivery in peripheral vascular disease.
Topics: Aged; Arterial Occlusive Diseases; Blood Gas Monitoring, Transcutaneous; Female; Humans; Leg; Male; | 1989 |
[Doppler flowmeter evaluation of the effects of the administration of buflomedil (irrodan) on peripheral circulation in patients with obstructive chronic arteriopathy].
Topics: Aged; Arterial Occlusive Diseases; Drug Evaluation; Humans; Male; Middle Aged; Pyrrolidines; Regiona | 1985 |
[Vascular and hemorheologic effects of buflomedil chlorhydrate in chronic obliterative arteriopathies of the legs].
Topics: Aged; Arterial Occlusive Diseases; Exercise Test; Humans; Leg; Male; Middle Aged; Pyrrolidines; Rheo | 1986 |
[Buflomedil chlorhydrate in peripheral vasculopathies].
Topics: Aged; Arterial Occlusive Diseases; Humans; Leg; Middle Aged; Pyrrolidines; Thermography; Vasodilator | 1986 |
[Scintigraphy with thallium-201 in the evaluation of vasoactive treatment in subjects with obliterative arteriopathies of the lower limbs].
Topics: Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Complications; Exercise Test; Female; | 1987 |
Metabolic effects of buflomedil hydrochloride.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adenylyl Cyclases; Adult; Aged; Arterial Occlusive D | 1985 |
[Buflomedil in the treatment of chronic peripheral arterial diseases. Case contribution].
Topics: Aged; Arterial Occlusive Diseases; Drug Tolerance; Female; Humans; Intermittent Claudication; Male; | 1985 |
[Digital blood flow in peripheral vascular diseases. Action of drugs: buflomedil].
Topics: Aged; Arterial Occlusive Diseases; Diabetic Angiopathies; Drug Evaluation; Female; Fingers; Humans; | 1988 |
[Acute severe coronary insufficiency during intravenous therapy with buflomedil hydrochloride. Description of 4 cases].
Topics: Acute Disease; Aged; Arterial Occlusive Diseases; Coronary Disease; Electrocardiography; Female; Hum | 1988 |
[Clinical experience and instrumental evaluation of buflomedil hydrochloride in the therapy of chronic obliterative arteriopathies of the legs].
Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Leg; Male; Middle Aged; Pyrrolidines; Rheology; U | 1986 |
Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV.
Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Leg; Male; Middle Aged; Pyrrolidines; Skin Ulcer; | 1986 |
[Flowmetric, thermometric and rheologic studies in obliterating arterial diseases of the lower extremities treated with buflomedil].
Topics: Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Viscosity; Drug Administration Schedul | 1985 |
[Epidemiologic study of peripheral obstructive arteriopathies: clinical effects of treatment with buflomedil chlorhydrate (Loftyl). Processing of data furnished by a polycenter study].
Topics: Administration, Oral; Age Factors; Aged; Arterial Occlusive Diseases; Female; Humans; Infusions, Par | 1985 |
Effects of buflomedil in a group of patients with chronic peripheral arterial diseases. Clinical and hemorheological evaluation.
Topics: Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Viscosity; Chronic Disease; Female; Hu | 1985 |