Compounds > buflomedil
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buflomedil and Arterial Obstructive Diseases

buflomedil has been researched along with Arterial Obstructive Diseases in 40 studies

buflomedil: RN given refers to parent cpd; synonym LL 1656 refers to HCl; structure

Research Excerpts

ExcerptRelevanceReference
"Buflomedil induced an increase of the same order of magnitude in plasma levels of adenosine and adenine nucleotides."2.68Increase in plasma levels of adenosine and adenine nucleotides after intravenous infusion of buflomedil in humans. ( Capecchi, PL; Chiavetta, M; De Lalla, A; Di Perri, T; Laghi Pasini, F; Sensi, S; Sodi, N; Volpi, L, 1995)
" and then orally, at a dosage of 600 mg/day."1.27Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV. ( Briguglio, E; Briguglio, F; Di Marco, V; Intilisano, A; Materia, G; Swat, M, 1986)
"Treatment with buflomedil for 3 months led to a significant improvement in signs and symptoms in all four clinical stages."1.27[Epidemiologic study of peripheral obstructive arteriopathies: clinical effects of treatment with buflomedil chlorhydrate (Loftyl). Processing of data furnished by a polycenter study]. ( , 1985)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199033 (82.50)18.7374
1990's6 (15.00)18.2507
2000's1 (2.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paoletti, V1
Mammarella, A1
Alessandrini, A1
Barlattani, M1
Trübestein, G4
Balzer, K2
Bisler, H2
Klüken, N2
Muller-Wiefel, H2
Unkel, B2
Mahfoud, Y2
Ziegler, W2
Marshall, M1
Sunder-Plassmann, L3
Gandolfo, AM1
Utz, C1
Tallarida, G1
Baldoni, F1
Peruzzi, G1
Raimondi, G1
Grimaldi, I1
Visigalli, G1
Gristina, S1
Massaro, M1
De Martinis, L1
Sangiorgi, M1
Forconi, S2
Pieragalli, D1
Acciavatti, A2
Del Bigo, C2
Galigani, C1
Ralli, L1
Guerrini, M2
Di Perri, T3
Lemke, R1
Klaus, D1
Trübestein, R2
Duong, QD1
Perego, MA1
Sergio, G1
Espureo, M1
Francisci, A1
Artale, F1
Materazzi, M1
Rossi, C1
Racenberg, J1
Intaglietta, M1
Messmer, K2
Balas, P1
Pagratis, N1
Becker, HM1
Tischler, R1
Decrinis, M1
Skursky-Roller, R1
Capecchi, PL1
Laghi Pasini, F1
Sodi, N1
Chiavetta, M1
Sensi, S1
De Lalla, A1
Volpi, L1
Marci, M1
Albiani, B1
Ricci, M1
Russo, F1
Joffre, F1
Meites, G1
Rousseau, H1
Staffin, C1
Allaert, FA1
Pelat, P1
Van den Brande, P1
Maurel, A1
Labs, KH1
Eichlisberger, R1
Jeanneret, C1
Frauchiger, B1
Aschwanden, M1
Jäger, KA1
Andreozzi, GM2
Lepore, R2
Ludwig, M1
Mannarino, E1
Pasqualini, L1
Maragoni, G1
Orlandi, U1
Abate, S1
Ferulano, GP1
Vanni, L1
Dilillo, S1
Picilli, M1
D'Alessio, E1
Coglitore, S1
Manganaro, A1
Barbera, MC1
Cento, D1
Buda, D1
Arrigo, F1
Consolo, F1
Dall'Antonia, F1
Perbellini, A1
Adami, CA1
Dal Cortivo, G1
Bucci, S1
Licata, G1
Parrinello, G1
Scaglione, R1
Indovina, A1
Pinto, A2
Capuana, G1
Mazzola, G1
Briguglio, F2
Di Marco, V2
Circosta, C1
Padovano, I1
Ragusa, S1
Saija, A1
Briguglio, E2
Longo, FN1
Potortì, F1
Urbano, O1
Perroni, GB1
Visconti, W1
Grillo, N1
Frausini, G1
Rotatori, P1
Gaggi, S1
Barone, A1
Pupita, F1
Romanò, M1
Spinelli, A1
Muzio, L1
Cazzani, E1
Baldini, MR1
Lucisano, V1
Margheriti, R1
Matone, P1
Morrieri, C1
Rugolo, A1
Corsi, V1
Allegra, C1
Avellone, G1
Cospite, M1
Del Guercio, R1
Nuzzaci, G1
Romeo, S1
Swat, M1
Materia, G1
Intilisano, A1
Heidrich, H1
Dorigo, B1
Raspanti, D1
Trapani, M1
Albanese, B1
Cameli, AM1
Digiesi, V1
Mozzi, E1
Chiurazzi, D1
Spinola, A1
Annoni, F1
Germiniani, R1

Reviews

1 review available for buflomedil and Arterial Obstructive Diseases

ArticleYear
[Treatment of chronic obliterative arteriopathy of the legs in the second Fontaine's stage. Personal experience with a buflomedil-pentoxifylline-defibrotide combination].
    La Clinica terapeutica, 1995, Volume: 146, Issue:3

    Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Drug Therapy, Combination; Fe

1995

Trials

12 trials available for buflomedil and Arterial Obstructive Diseases

ArticleYear
[Comparative study of various schedules of buflomedil treatment in peripheral arterial insufficiency of the lower limbs. Evaluation of its therapeutic efficacy].
    La Clinica terapeutica, 1984, Jul-15, Volume: 110, Issue:1

    Topics: Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Drug Administration Schedule; Fe

1984
Buflomedil in arterial occlusive disease: results of a controlled multicenter study.
    Angiology, 1984, Volume: 35, Issue:8

    Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Hu

1984
[Buflomedil in arterial occlusive disease. Results of a controlled study].
    Deutsche medizinische Wochenschrift (1946), 1982, Dec-24, Volume: 107, Issue:51-52

    Topics: Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Femoral Ar

1982
Comparative evaluation of the effectiveness of buflomedil and pentoxifylline in patients with arterial occlusive disease.
    Angiology, 1981, Volume: 32, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Bli

1981
Increase in plasma levels of adenosine and adenine nucleotides after intravenous infusion of buflomedil in humans.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphospha

1995
[Effect of buflomedil perfusion on peripheral tissue oxygenation during transluminal angioplasty in patients with advanced arteriopathy of the lower limbs].
    Annales de radiologie, 1994, Volume: 37, Issue:3

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Arterial Occlusive Diseases; Blood Gas Monitoring, Tr

1994
A placebo-controlled study of the effects of intravenous Buflomedil on foot skin microcirculation in patients with severe intermittent claudication.
    Angiology, 1998, Volume: 49, Issue:2

    Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Dose-Response Relationship, D

1998
[Action and tolerability of delayed-action buflomedil in obliterating arteriopathies of the lower limbs. A multicenter study].
    La Clinica terapeutica, 1990, Nov-30, Volume: 135, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Delayed-Action Preparations

1990
[Bencyclane in stage II arterial occlusive disease. Results of a controlled study].
    Fortschritte der Medizin, 1989, Dec-20, Volume: 107, Issue:36

    Topics: Aged; Arterial Occlusive Diseases; Bencyclane; Cycloheptanes; Double-Blind Method; Female; Humans; I

1989
[Effects of buflomedil on peripheral arteriopathies. An open clinical study].
    Minerva cardioangiologica, 1988, Volume: 36, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic

1988
[Multicenter study on the therapeutic activity of buflomedil chlorhydrate in obliterative arteriopathies of the legs].
    La Clinica terapeutica, 1986, Oct-15, Volume: 119, Issue:1

    Topics: Arterial Occlusive Diseases; Blood Volume; Clinical Trials as Topic; Female; Humans; Leg; Male; Pyrr

1986
[Vasoactive drugs in peripheral arterial perfusion disorders. Problems, principles and results of the determination of therapeutic efficacy].
    Deutsche medizinische Wochenschrift (1946), 1985, Aug-02, Volume: 110, Issue:31-32

    Topics: Arterial Occlusive Diseases; Cardiovascular Agents; Cinnarizine; Clinical Trials as Topic; Dihydroer

1985

Other Studies

27 other studies available for buflomedil and Arterial Obstructive Diseases

ArticleYear
[Arterio-vascular diseases. New trends in diagnosis and therapy].
    MMW, Munchener medizinische Wochenschrift, 1983, May-13, Volume: 125, Issue:19

    Topics: Arterial Occlusive Diseases; Humans; Intermittent Claudication; Pyrrolidines; Vasodilator Agents

1983
[Effectiveness of buflomedil in arterial occlusive disease. Modification of transcutaneous oxygen pressure in a placebo-controlled double-blind study].
    MMW, Munchener medizinische Wochenschrift, 1984, Mar-02, Volume: 126, Issue:9

    Topics: Arterial Occlusive Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Leg; Oxy

1984
[Effects of the administration of buflomedil-hydrochloride on the arterial circulation of the legs in patients with obliterative arteriopathies].
    Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:8

    Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Drug Evaluation; Female; Humans; Leg; Male; Middl

1983
Positive effect of oral buflomedil on exercise-induced haemorheological damage and on claudication distance in peripheral obliterative arterial disease patients.
    The Journal of international medical research, 1984, Volume: 12, Issue:3

    Topics: Administration, Oral; Arterial Occlusive Diseases; Blood Viscosity; Female; Humans; Hydrogen-Ion Con

1984
[Acute affect of buflomedil hydrochloride (bufedil) on transcutaneously measured oxygen pressures in patients with peripheral arterial occlusive disease].
    VASA. Zeitschrift fur Gefasskrankheiten, 1984, Volume: 13, Issue:2

    Topics: Arterial Occlusive Diseases; Humans; Oxygen; Pyrrolidines; Vasodilator Agents

1984
Haemodynamic and haemorheological effects of buflomedil in patients with peripheral occlusive arterial disease.
    Current medical research and opinion, 1982, Volume: 8, Issue:3

    Topics: Arterial Occlusive Diseases; Blood Circulation; Blood Pressure; Blood Viscosity; Erythrocytes; Femal

1982
Protective effects of buflomedil against exercise-induced reductions in regional erythrocyte deformability of patients with peripheral arterial disease.
    The Journal of international medical research, 1982, Volume: 10, Issue:6

    Topics: Arterial Occlusive Diseases; Erythrocytes; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged;

1982
[Effect of the vasoactive drug buflomedil in arterial occlusive disease].
    Fortschritte der Medizin, 1982, Nov-04, Volume: 100, Issue:41

    Topics: Animals; Arterial Occlusive Diseases; Blood Viscosity; Collateral Circulation; Dogs; Hemodynamics; H

1982
[Improved microcirculation and collateral circulation in arterial occlusive diseases of the lower extremity].
    Fortschritte der Medizin, 1981, Nov-19, Volume: 99, Issue:43

    Topics: Animals; Arterial Occlusive Diseases; Collateral Circulation; Dogs; Hemodilution; Hindlimb; Intermit

1981
Experience with buflomedil in peripheral arterial occlusive disease.
    Angiology, 1981, Volume: 32, Issue:10

    Topics: Adult; Aged; Ankle; Arterial Occlusive Diseases; Female; Humans; Hyperemia; Leg; Male; Middle Aged;

1981
Tissue pO2 and transcutaneous pO2 as guidelines in experimental and clinical drug evaluation.
    Angiology, 1981, Volume: 32, Issue:10

    Topics: Animals; Arterial Occlusive Diseases; Arteriosclerosis; Chronic Disease; Collateral Circulation; Dog

1981
[Can vasomotion be modified by vasoactive substances or hemodilution?].
    Acta medica Austriaca, 1994, Volume: 21, Issue:5

    Topics: Alprostadil; Arterial Occlusive Diseases; Blood Flow Velocity; Capillaries; Combined Modality Therap

1994
Assessment of collateral perfusion: a pharmacodynamic study with buflomedil hydrochloride.
    Angiology, 2000, Volume: 51, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Collateral Circulation; Female; Femoral

2000
Effect of buflomedil chlorhydrate on local oxygen delivery in peripheral vascular disease.
    Angiology, 1989, Volume: 40, Issue:6

    Topics: Aged; Arterial Occlusive Diseases; Blood Gas Monitoring, Transcutaneous; Female; Humans; Leg; Male;

1989
[Doppler flowmeter evaluation of the effects of the administration of buflomedil (irrodan) on peripheral circulation in patients with obstructive chronic arteriopathy].
    Minerva cardioangiologica, 1985, Volume: 33, Issue:11

    Topics: Aged; Arterial Occlusive Diseases; Drug Evaluation; Humans; Male; Middle Aged; Pyrrolidines; Regiona

1985
[Vascular and hemorheologic effects of buflomedil chlorhydrate in chronic obliterative arteriopathies of the legs].
    Minerva cardioangiologica, 1986, Volume: 34, Issue:11

    Topics: Aged; Arterial Occlusive Diseases; Exercise Test; Humans; Leg; Male; Middle Aged; Pyrrolidines; Rheo

1986
[Buflomedil chlorhydrate in peripheral vasculopathies].
    La Clinica terapeutica, 1986, Dec-15, Volume: 119, Issue:5

    Topics: Aged; Arterial Occlusive Diseases; Humans; Leg; Middle Aged; Pyrrolidines; Thermography; Vasodilator

1986
[Scintigraphy with thallium-201 in the evaluation of vasoactive treatment in subjects with obliterative arteriopathies of the lower limbs].
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:11

    Topics: Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Complications; Exercise Test; Female;

1987
Metabolic effects of buflomedil hydrochloride.
    The Journal of international medical research, 1985, Volume: 13, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adenylyl Cyclases; Adult; Aged; Arterial Occlusive D

1985
[Buflomedil in the treatment of chronic peripheral arterial diseases. Case contribution].
    Minerva medica, 1985, May-12, Volume: 76, Issue:19-20

    Topics: Aged; Arterial Occlusive Diseases; Drug Tolerance; Female; Humans; Intermittent Claudication; Male;

1985
[Digital blood flow in peripheral vascular diseases. Action of drugs: buflomedil].
    Minerva cardioangiologica, 1988, Volume: 36, Issue:6

    Topics: Aged; Arterial Occlusive Diseases; Diabetic Angiopathies; Drug Evaluation; Female; Fingers; Humans;

1988
[Acute severe coronary insufficiency during intravenous therapy with buflomedil hydrochloride. Description of 4 cases].
    Minerva cardioangiologica, 1988, Volume: 36, Issue:9

    Topics: Acute Disease; Aged; Arterial Occlusive Diseases; Coronary Disease; Electrocardiography; Female; Hum

1988
[Clinical experience and instrumental evaluation of buflomedil hydrochloride in the therapy of chronic obliterative arteriopathies of the legs].
    La Clinica terapeutica, 1986, Jun-30, Volume: 117, Issue:6

    Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Leg; Male; Middle Aged; Pyrrolidines; Rheology; U

1986
Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV.
    The Journal of international medical research, 1986, Volume: 14, Issue:3

    Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Leg; Male; Middle Aged; Pyrrolidines; Skin Ulcer;

1986
[Flowmetric, thermometric and rheologic studies in obliterating arterial diseases of the lower extremities treated with buflomedil].
    Minerva medica, 1985, Feb-25, Volume: 76, Issue:7

    Topics: Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Viscosity; Drug Administration Schedul

1985
[Epidemiologic study of peripheral obstructive arteriopathies: clinical effects of treatment with buflomedil chlorhydrate (Loftyl). Processing of data furnished by a polycenter study].
    Minerva medica, 1985, Oct-13, Volume: 76, Issue:39

    Topics: Administration, Oral; Age Factors; Aged; Arterial Occlusive Diseases; Female; Humans; Infusions, Par

1985
Effects of buflomedil in a group of patients with chronic peripheral arterial diseases. Clinical and hemorheological evaluation.
    The Journal of international medical research, 1985, Volume: 13, Issue:6

    Topics: Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Viscosity; Chronic Disease; Female; Hu

1985