bufalin and Osteosarcoma

bufalin has been researched along with Osteosarcoma in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Fang, X; He, Z; Jiang, XH; Li, Y; Lu, SL; Su, ZC; Wang, H; Zheng, YD1
Chang, Y; Liu, T; Wei, X; Zhan, H; Zhao, Y; Zheng, B1
Bi, Z; Wang, D1
Huang, G; Liao, HY; Shen, JN; Wang, B; Wen, LL; Xie, XB; Yin, JQ; Zou, CY1
Cao, Y; Chang, Y; Gu, W; Pang, J; Shi, Y; Wang, S; Zhao, Y1
Chen, Y; Gao, P; Li, M; Li, Z; Zhang, J; Zhou, X1
Au, MK; Chen, YL; Chung, JG; Lee, CH; Lee, MH; Lu, HF; Shih, YL1
Huang, G; Jia, Q; Shen, JN; Wang, J; Xie, XB; Yin, JQ; Zou, CY1
Chen, YY; Chueh, FS; Chung, JG; Ho, HC; Huang, AC; Kuo, CL; Liao, CL; Yang, JS1
Colombo, C; Gao, ZH; He, WL; Huang, G; Jia, Q; Shen, JN; Tang, QL; Wang, J; Wen, LL; Xie, XB; Yin, JQ; Zou, CY1
Guo, QC; Huang, G; Jin, S; Li, FB; Li, HM; Shen, JN; Su, WW; Wang, J; Yin, JQ; Zou, CY1

Other Studies

11 other study(ies) available for bufalin and Osteosarcoma

ArticleYear
Bufalin induces apoptosis and autophagy via the Ca2+/CaMKKβ/AMPK/Beclin1 signaling pathway in osteosarcoma cells.
    Cell biology international, 2023, Volume: 47, Issue:8

    Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Beclin-1; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line, Tumor; Humans; Osteosarcoma; Signal Transduction

2023
Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:2

    Topics: AC133 Antigen; Animals; Antigens, CD; Bufanolides; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Mice; Neoplastic Stem Cells; Octamer Transcription Factor-3; Osteosarcoma; Peptides

2014
Bufalin inhibited the growth of human osteosarcoma MG-63 cells via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Bufanolides; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Membrane Potential, Mitochondrial; Mitochondria; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species

2014
[Proteomics research of bufalin-induced apoptosis in osteosarcoma cell lines].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:14

    Topics: Antineoplastic Agents; Apoptosis; Bufanolides; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Proteomics

2014
Bufalin Inhibits the Differentiation and Proliferation of Cancer Stem Cells Derived from Primary Osteosarcoma Cells through Mir-148a.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 36, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Bufanolides; Cell Differentiation; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation, Neoplastic; Humans; Medicine, Chinese Traditional; Mice; MicroRNAs; Neoplastic Stem Cells; Osteosarcoma; Primary Cell Culture; Signal Transduction

2015
Bufalin induces apoptosis in the U‑2OS human osteosarcoma cell line via triggering the mitochondrial pathway.
    Molecular medicine reports, 2016, Volume: 13, Issue:1

    Topics: Apoptosis; Blotting, Western; Bufanolides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclosporine; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Osteosarcoma; Signal Transduction

2016
Bufalin Induces Apoptosis of Human Osteosarcoma U-2 OS Cells through Endoplasmic Reticulum Stress, Caspase- and Mitochondria-Dependent Signaling Pathways.
    Molecules (Basel, Switzerland), 2017, Mar-10, Volume: 22, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Bone Neoplasms; Bufanolides; Calcium; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Humans; Membrane Potential, Mitochondrial; Mitochondria; Osteosarcoma; Protein Transport; Reactive Oxygen Species; Signal Transduction

2017
[Bufalin induces apoptosis in osteosarcoma U-2OS and U-2OS methotrexate 300-resistant cell lines in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Bufanolides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Methotrexate; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Tetrahydrofolate Dehydrogenase; Tumor Suppressor Protein p53

2010
Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways.
    Environmental toxicology, 2014, Volume: 29, Issue:1

    Topics: Antineoplastic Agents; Bone Neoplasms; Bufanolides; Cell Line, Tumor; Cell Movement; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Osteosarcoma; Protein Kinase Inhibitors

2014
Critical role of heat shock protein 27 in bufalin-induced apoptosis in human osteosarcomas: a proteomic-based research.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Bufanolides; Cell Line, Tumor; Cytochromes c; Female; Gene Expression Regulation, Neoplastic; HSP27 Heat-Shock Proteins; Humans; Mice; Osteosarcoma; Proteome; Proteomics; Proto-Oncogene Proteins c-akt; Transcription Factor RelA; Xenograft Model Antitumor Assays

2012
Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bufanolides; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Resistance, Neoplasm; Humans; Methotrexate; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Tetrahydrofolate Dehydrogenase

2007