bufalin has been researched along with Lung Neoplasms in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (75.00) | 24.3611 |
| 2020's | 5 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, S; Li, F; Li, L; Liu, F; Lu, X; Shi, S; Tian, X; Xiang, L; Zang, H; Zhao, S | 1 |
| Cheng, X; Miao, Y; Qian, Z; Tian, X; Wu, M; Xu, X; Yu, Y | 1 |
| Kim, NY; Kim, S; Lee, C; Suh, YA | 1 |
| Dai, X; Huang, X; Liu, Y; Liu, Z; Wang, L; Xiang, Y; Xu, L; Yang, L; Zhao, C; Zhao, H; Zhou, F; Zhuang, Y | 1 |
| Jin, J; Qin, H; Wang, K; Xin, X; Yao, Z | 1 |
| Cao, F; Cui, YH; Kang, XH; Kou, WZ; Lu, P; Miao, ZH; Wang, LF; Wang, Y; Xu, ZY; Zhang, JH; Zhang, QQ | 1 |
| Fu, L; Zhang, C | 1 |
| Chen, Q; Liu, J | 1 |
| Cao, F; Gong, YB; Kang, XH; Liao, MJ; Lu, ZH; Miao, ZH; Wang, Y; Xu, ZY; Zhao, KL | 1 |
| Deng, HB; Gong, YB; Kang, XH; Wang, LF; Wang, ZQ; Wu, J; Xu, ZY; Zhao, XZ | 1 |
| Wu, WZ; Yang, YK; Zhang, ZJ | 1 |
| Chen, JC; Chung, JG; Hsia, TC; Hsiao, YT; Hsu, SC; Hsu, WH; Lin, JH; Wu, SH; Yang, ST | 1 |
| Chung, JG; Hsia, TC; Hsiao, YT; Hsu, SC; Hsu, WH; Lin, JH; Wu, SH; Wu, TY; Yang, ST | 1 |
| An, Q; Ding, DW; Huang, XE; Zhang, X; Zhang, YH | 1 |
| Che, X; Fan, Y; Hou, K; Hu, X; Li, C; Liu, S; Liu, Y; Ma, Y; Qu, X; Wen, T; Zhao, L | 1 |
| Chen, JC; Chung, JG; Hsia, TC; Hsiao, YT; Hsu, SC; Hsu, WH; Kuo, CL; Liu, HC; Wu, PP; Wu, SH; Yu, FS | 1 |
| Cui, Y; Gong, Y; Kang, X; Lu, P; Wang, Y; Xu, Z; Zhang, Q | 1 |
| Cheng, YD; Chung, JG; Hsia, TC; Hsiao, YT; Huang, AC; Kuo, CL; Lin, TS; Ma, YS; Peng, SF; Yang, MD | 1 |
| Li, E; Liu, Y; Wang, K; Yu, Y; Zhu, Z | 1 |
| Li, E; Liu, Y; Ma, G; Sun, H; Wang, Z; Zhu, Z | 1 |
20 other study(ies) available for bufalin and Lung Neoplasms
| Article | Year |
|---|---|
Molecular and metabolic mechanisms of bufalin against lung adenocarcinoma: New and comprehensive evidences from network pharmacology, metabolomics and molecular biology experiment.
Topics: Adenocarcinoma of Lung; Animals; Drugs, Chinese Herbal; Lung Neoplasms; Mice; Mice, Nude; Molecular Biology; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases | 2023 |
Bufalin inhibits the proliferation of lung cancer cells by suppressing Hippo-YAP pathway.
Topics: Adaptor Proteins, Signal Transducing; Cell Proliferation; Humans; Lung Neoplasms; Protein Serine-Threonine Kinases; Transcription Factors | 2023 |
Bufalin down-regulates Axl expression to inhibit cell proliferation and induce apoptosis in non-small-cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Axl Receptor Tyrosine Kinase; Bufanolides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lung Neoplasms; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Transcription, Genetic | 2020 |
Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting the CDK9/STAT3 signalling pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bufanolides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Enzyme Inhibitors; Female; G2 Phase Cell Cycle Checkpoints; Heterografts; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Molecular Docking Simulation; Prodrugs; Rats; RNA, Small Interfering; STAT3 Transcription Factor | 2021 |
Bufalin inhibits the malignant development of non-small cell lung cancer by mediating the circ_0046264/miR-522-3p axis.
Topics: A549 Cells; Animals; Antineoplastic Agents; Bufanolides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; MicroRNAs; RNA, Circular; Xenograft Model Antitumor Assays | 2021 |
Degradation of Mcl-1 through GSK-3β Activation Regulates Apoptosis Induced by Bufalin in Non-Small Cell Lung Cancer H1975 Cells.
Topics: Apoptosis; Bufanolides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Enzyme Activation; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proteolysis | 2017 |
[Effects of bufalin combined with doxorubicin on the proliferation and apoptosis of human lung cancer cell line A549 in vitro].
Topics: A549 Cells; Apoptosis; Bufanolides; Cell Proliferation; Doxorubicin; Humans; Lung Neoplasms | 2017 |
Transferrin and folic acid co-modified bufalin-loaded nanoliposomes: preparation, characterization, and application in anticancer activity.
Topics: A549 Cells; Animals; Antineoplastic Agents; Bufanolides; Cell Death; Diagnostic Imaging; Drug Liberation; Female; Folic Acid; Humans; Inhibitory Concentration 50; Liposomes; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Optical Imaging; Transferrin; Xenograft Model Antitumor Assays | 2018 |
Degradation of MCL-1 by bufalin reverses acquired resistance to osimertinib in EGFR-mutant lung cancer.
Topics: Acrylamides; Aniline Compounds; Animals; Antineoplastic Agents; Bufanolides; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Fluorescent Antibody Technique; Genes, erbB-1; In Situ Nick-End Labeling; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation | 2019 |
[Effect of bufalin combined gefitinib on lung cancer H1975 cells and its mechanisms research].
Topics: Bufanolides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction | 2013 |
Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice.
Topics: Animals; Apoptosis; beta Catenin; Bufanolides; Cadherins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Nude; Necrosis; Neoplasm Staging; Proto-Oncogene Proteins c-akt; Signal Transduction; Survival Analysis; Xenograft Model Antitumor Assays | 2014 |
Bufalin alters gene expressions associated DNA damage, cell cycle, and apoptosis in human lung cancer NCI-H460 cells in vitro.
Topics: Apoptosis; Bufanolides; Cell Cycle; DNA Damage; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Lung Neoplasms | 2014 |
Bufalin induces cell death in human lung cancer cells through disruption of DNA damage response pathways.
Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; BRCA1 Protein; Bufanolides; Cell Cycle Proteins; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; DNA-Activated Protein Kinase; Exoribonucleases; Genes, cdc; Humans; Lung Neoplasms; Nuclear Proteins; Trans-Activators; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2014 |
Bufalin induces mitochondrial pathway-mediated apoptosis in lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Blotting, Western; Bufanolides; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Up-Regulation | 2014 |
Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors.
Topics: Antineoplastic Agents; Bufanolides; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Lung; Lung Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta | 2015 |
Bufalin Inhibits NCI-H460 Human Lung Cancer Cell Metastasis In Vitro by Inhibiting MAPKs, MMPs, and NF-κB Pathways.
Topics: Bufanolides; Cell Line, Tumor; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Signal Transduction | 2015 |
[Bufalin reverses hepatocyte growth factor-induced resistance to afatinib in H1975 lung cancer cells].
Topics: Afatinib; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bufanolides; Cadherins; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Hepatocyte Growth Factor; Humans; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Quinazolines; Signal Transduction; Tetrazolium Salts; Thiazoles | 2015 |
Bufalin inhibits gefitinib resistant NCI-H460 human lung cancer cell migration and invasion in vitro.
Topics: Antineoplastic Agents; Bufanolides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Quinazolines; rhoA GTP-Binding Protein; Signal Transduction; SOS1 Protein | 2016 |
[Effect of Bufalin on proliferation and apoptosis of human non-small cell lung cancer A549 cell].
Topics: Animals; Apoptosis; Bufanolides; Bufonidae; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms | 2010 |
Bufalin induces lung cancer cell apoptosis via the inhibition of PI3K/Akt pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Bufanolides; Cell Proliferation; Down-Regulation; Humans; Lung Neoplasms; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Signal Transduction; Tumor Cells, Cultured | 2012 |