Compounds > bufalin

bufalin and Colonic Neoplasms

bufalin has been researched along with Colonic Neoplasms in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, C; Liu, T; Qiu, YY; Shi, XJ; Yin, PH; Yu, H; Yuan, YX1
Fan, G; Gao, F; Han, L; He, X; Huang, X; Qiu, Y; Tang, X; Xu, K; Yin, P; Yuan, Y; Yuan, Z; Zhang, Y1
Fang, L; Lin, XT; Wu, D; Xie, CM; Zhou, WY1
Chan, WY; Cheng, CH; Xie, CM; Yu, S; Zhao, J1
Duan, Y; Hou, L; Li, Q; Liu, P; Liu, X; Qin, J; Qiu, M; Qiu, Y; Wang, Y; Yin, P1
Gao, Y; Li, E; Liu, X; Liu, Y; Ma, G; Qu, X; Sun, H; Wang, Q; Wang, Z; Yu, Y; Zhu, Z1

Other Studies

6 other study(ies) available for bufalin and Colonic Neoplasms

ArticleYear
Increasing the anticancer performance of bufalin (BUF) by introducing an endosome-escaping polymer and tumor-targeting peptide in the design of a polymeric prodrug.
    Colloids and surfaces. B, Biointerfaces, 2018, Jun-01, Volume: 166

    Topics: Animals; Antineoplastic Agents; Bufanolides; Cell Survival; Colonic Neoplasms; Drug Delivery Systems; Endosomes; Methacrylates; Mice; Nanoparticles; Polyethylene Glycols; Polymers; Prodrugs

2018
Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bufanolides; Chitosan; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Mice, Nude; Micelles; Oligopeptides; Oligosaccharides; Rhodamine 123; Tumor Burden; Vitamin E

2018
Bufalin induces apoptosis via mitochondrial ROS-mediated caspase-3 activation in HCT-116 and SW620 human colon cancer cells.
    Drug and chemical toxicology, 2019, Volume: 42, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Bufanolides; Caspase 3; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Mitochondria; Reactive Oxygen Species

2019
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
    Free radical biology & medicine, 2011, Oct-01, Volume: 51, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Blotting, Western; Bufanolides; Bufonidae; Caspase 3; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression; Gene Silencing; Humans; MAP Kinase Kinase 4; Membrane Proteins; Microtubule-Associated Proteins; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Small Interfering; Up-Regulation

2011
Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Animals; Antineoplastic Agents; Bufanolides; Cell Survival; Colonic Neoplasms; Drug Carriers; Female; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Oligopeptides; Particle Size; Polyesters; Polyethylene Glycols; Polylysine; Spectrophotometry, Ultraviolet; Tissue Distribution; Xenograft Model Antitumor Assays

2012
Inhibition of Jak-STAT3 pathway enhances bufalin-induced apoptosis in colon cancer SW620 cells.
    World journal of surgical oncology, 2012, Oct-30, Volume: 10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bufanolides; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Enzyme Inhibitors; Humans; Janus Kinase 1; Mitotic Index; STAT3 Transcription Factor; Tumor Cells, Cultured; Tyrphostins

2012