bucladesine has been researched along with Interstitial Cell Tumor in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (32.73) | 18.7374 |
| 1990's | 24 (43.64) | 18.2507 |
| 2000's | 12 (21.82) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, R; Daly, E; Galano, M; Issop, L; Kaur, P; Lee, S; Papadopoulos, V; Sanyal, E; Taylor, L; Venugopal, S | 1 |
| Huhtaniemi, IT; Manna, PR; Stocco, DM | 1 |
| Keeney, DS; Mason, JI | 1 |
| Eubank, DW; Huhtaniemi, IT; Manna, PR; Stocco, DM; Wang, XJ | 1 |
| Azhar, S; Bose, HS; Jo, Y; Leers-Sucheta, S; Miller, WL; Rao, RM; Stocco, DM | 1 |
| Dyson, MT; Jo, Y; Stocco, DM; Wang, X | 1 |
| Dyson, MT; Eubank, DW; Jo, Y; Stocco, DM; Wang, XJ | 1 |
| Jo, Y; Khan, SA; King, SR; Stocco, DM | 1 |
| Grammas, P; King, SR; Schiffer, RB; Stocco, DM; Wang, X; Yin, X | 1 |
| Cooke, BA; Dix, CJ; Habberfield, AD | 1 |
| Bakker, GH; Hoogerbrugge, W; Rommerts, FF; van der Molen, HJ | 1 |
| Fishman, PH; Rebois, RV | 2 |
| Cooke, BA; Dix, CJ; Schumacher, M | 1 |
| Clark, BJ; King, SR; Orly, J; Ronen-Fuhrmann, T; Stocco, DM; Timberg, R | 1 |
| Clark, BJ; King, S; Stocco, DM | 1 |
| Bussmann, LE; Charreau, EH; Pignataro, OP; Vladusic, EA | 1 |
| Clark, BJ; Stocco, DM; Wells, J | 1 |
| Ascoli, M; Stocco, DM | 1 |
| Freeman, DA; Gocze, PM; Porpaczy, Z | 1 |
| Freeman, DA | 4 |
| Cooke, BA; Michael, AE; Peterson, S; Ramnath, HI; Stocco, DM | 1 |
| Freeman, DA; Porpaczy, Z; Tomasek, JJ | 1 |
| Choi, HS; Kwon, HB; Lee, HK; Soh, J; Yoo, MS | 1 |
| Stocco, DM; Walsh, LP; Wang, X | 1 |
| Chen, CF; Chuang, YM; Huang, BM; Leu, SF | 1 |
| Huang, BM; Lai, HY; Liu, MY; Tsai, ML; Yang, BC; Yang, HY | 1 |
| Kobayashi, A; Maeda, M; Nakagawa, R; Sakai, Y; Takashima, A; Terada, T | 1 |
| Lalli, E; Liu, Z; Murphy, BD; Sassone-Corsi, P; Soh, J; Stocco, DM; Walsh, LP | 1 |
| King, SR; Rommerts, FF; Span, PN | 1 |
| Khan, SA; Stocco, DM | 1 |
| Stocco, DM | 1 |
| Freeman, DA; Ontko, JA | 1 |
| Freeman, DA; Gocze, PM | 1 |
| Chen, CL; Feng, ZM; Pignataro, OP | 1 |
| Chaudhary, LR; Stocco, DM | 3 |
| Cooke, BA; West, AP | 1 |
| Chen, W; Stocco, DM | 1 |
| Freeman, DA; Nagy, L | 2 |
| Cooke, BA; Rose, MP; West, AP | 1 |
| Ascoli, M; Inagami, T; Pandey, KN | 1 |
| Ascoli, M; Euffa, J; Segaloff, DL | 1 |
| Kilgore, MW; Stocco, DM | 2 |
| Czerwiec, FS; Melner, MH; Puett, D | 1 |
| Ascoli, M; Segaloff, DL | 1 |
| Fishman, PH; Rebois, RV; Zaremba, T | 1 |
| Rommerts, FF; Terpstra, P; van der Molen, HJ | 1 |
| Longcope, C; Mordes, JP; Orczyk, GP | 1 |
55 other study(ies) available for bucladesine and Interstitial Cell Tumor
| Article | Year |
|---|---|
Dynamic Remodeling of Membranes and Their Lipids during Acute Hormone-Induced Steroidogenesis in MA-10 Mouse Leydig Tumor Cells.
Topics: Animals; ATPases Associated with Diverse Cellular Activities; Bucladesine; Cell Line, Tumor; Cell Membrane; Cholesterol; Cyclic AMP; Endoplasmic Reticulum; Gene Knockdown Techniques; Leydig Cell Tumor; Lipidomics; Male; Membrane Lipids; Mice; Microscopy, Electron, Transmission; Mitochondrial Membranes; Mitochondrial Proteins; Models, Biological; Steroids; Testicular Neoplasms | 2021 |
Mechanisms of protein kinase C signaling in the modulation of 3',5'-cyclic adenosine monophosphate-mediated steroidogenesis in mouse gonadal cells.
Topics: Animals; Bucladesine; CREB-Binding Protein; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Granulosa Cell Tumor; Leydig Cell Tumor; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Phosphoproteins; Protein Kinase C; Receptors, Steroid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2009 |
Regulation of expression of 3β-hydroxysteroid dehydrogenase is mediated by cAMP in rat Leydig cells and H540 rat Leydig tumor cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cell Line, Tumor; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Testis | 1992 |
Mechanisms of epidermal growth factor signaling: regulation of steroid biosynthesis and the steroidogenic acute regulatory protein in mouse Leydig tumor cells.
Topics: Animals; Arachidonic Acid; Base Sequence; Bucladesine; Chorionic Gonadotropin; Epidermal Growth Factor; Iodine Radioisotopes; Leydig Cell Tumor; Male; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Phosphoproteins; Progesterone; Receptors, LH; RNA, Messenger; Signal Transduction; Steroids; Testicular Neoplasms; Tumor Cells, Cultured | 2002 |
Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport.
Topics: Animals; Base Sequence; Biological Transport, Active; Bucladesine; CD36 Antigens; Cholesterol; Cholesterol Esters; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Leydig Cell Tumor; Male; Membrane Proteins; Mice; Mitochondria; Phosphoproteins; Rats; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Steroids; Sterol Esterase; Testicular Neoplasms; Tumor Cells, Cultured | 2003 |
Inhibition of cyclooxygenase-2 activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells.
Topics: Animals; Bucladesine; COS Cells; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Indomethacin; Isoenzymes; Leydig Cell Tumor; Leydig Cells; Male; Membrane Proteins; Mice; Phosphoproteins; Progesterone; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Steroids; Transcription, Genetic; Transfection | 2003 |
Involvement of 5-lipoxygenase metabolites of arachidonic acid in cyclic AMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Base Sequence; Bucladesine; Cyclic AMP; DNA Primers; Female; Gene Expression Regulation; Genes, Reporter; Hydroxyeicosatetraenoic Acids; Kinetics; Leydig Cell Tumor; Luciferases; Membrane Proteins; Mice; Mutagenesis, Insertional; Ovarian Neoplasms; Phosphoproteins; Promoter Regions, Genetic; Recombinant Proteins; Sequence Deletion; Tumor Cells, Cultured | 2003 |
Involvement of protein kinase C and cyclic adenosine 3',5'-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells.
Topics: Animals; Blotting, Western; Bucladesine; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Leydig Cell Tumor; Leydig Cells; Male; Phosphoproteins; Progesterone; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; Steroids; Tetradecanoylphorbol Acetate | 2005 |
Inhibition of thromboxane a synthase activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells.
Topics: Animals; Bucladesine; Cell Line, Tumor; Cyclic AMP; DAX-1 Orphan Nuclear Receptor; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation, Enzymologic; Leydig Cell Tumor; Leydig Cells; Male; Mice; Phosphoproteins; RNA, Small Interfering; Steroids; Testicular Neoplasms; Thromboxane A2; Thromboxane-A Synthase; Transcription, Genetic | 2008 |
Characterization of the homologous and heterologous desensitization of rat Leydig-tumour-cell adenylate cyclase.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Centrifugation, Density Gradient; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; In Vitro Techniques; Isoproterenol; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Prostaglandins E; Rats | 1984 |
LH-dependent steroid production and protein phosphorylation in culture of rat tumour Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Hydroxycholesterols; Leydig Cell Tumor; Luteinizing Hormone; Molecular Weight; Phosphoproteins; Pregnenolone; Protein Kinases; Rats | 1983 |
Down-regulation of gonadotropin receptors in a murine Leydig tumor cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Kinetics; Leydig Cell Tumor; Male; Mice; Receptors, Cell Surface; Receptors, LH; Temperature; Testicular Neoplasms | 1984 |
Desensitization of tumour Leydig cells by lutropin: evidence for uncoupling of the lutropin receptor from the guanine nucleotide-binding protein.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Membrane; Cholera Toxin; Cyclic AMP; GTP-Binding Proteins; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Rats; Receptors, Cell Surface; Receptors, LH | 1982 |
Steroid production after in vitro transcription, translation, and mitochondrial processing of protein products of complementary deoxyribonucleic acid for steroidogenic acute regulatory protein.
Topics: Animals; Bucladesine; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Female; Gene Expression; Leydig Cell Tumor; Mice; Microscopy, Immunoelectron; Mitochondria; Neoplasm Proteins; Phosphoproteins; Progesterone; Protein Biosynthesis; Protein Precursors; Rats; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Differential effects of dimethylsulfoxide on steroidogenesis in mouse MA-10 and rat R2C Leydig tumor cells.
Topics: Animals; Bucladesine; Cyclic AMP; Dimethyl Sulfoxide; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Mice; Mitochondria; Phosphoproteins; Phosphorylation; Progesterone; Protein Biosynthesis; Rats; Tumor Cells, Cultured | 1995 |
Regulation of the cholesterol ester cycle and progesterone synthesis by juvenile hormone in MA-10 Leydig tumor cells.
Topics: Bucladesine; Cell Membrane; Cholesterol; Cholesterol Esters; Hydroxycholesterols; Juvenile Hormones; Leydig Cell Tumor; Progesterone; Pyrans; Sesquiterpenes; Sterol Esterase | 1995 |
The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells.
Topics: Animals; Bucladesine; Hydrogen Peroxide; Hydroxycholesterols; Leydig Cell Tumor; Mice; Mitochondria; Neoplasm Proteins; Pregnenolone; Progesterone; Proteins; Steroids; Tumor Cells, Cultured | 1993 |
The use of genetic manipulation of MA-10 Leydig tumor cells to demonstrate the role of mitochondrial proteins in the acute regulation of steroidogenesis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Chorionic Gonadotropin; Clone Cells; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gentamicins; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Male; Metallothionein; Mice; Mitochondria; Molecular Weight; Progesterone; Promoter Regions, Genetic; Protein Biosynthesis; Protein Kinases; Proteins; Testicular Neoplasms; Transfection; Tumor Cells, Cultured; Zinc | 1993 |
Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Topics: Bucladesine; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, Gas; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Finasteride; Hydroxycholesterols; Leydig Cell Tumor; Osmolar Concentration; Progesterone; Tumor Cells, Cultured | 1993 |
Constitutive steroidogenesis does not require the actions of cAMP on cholesteryl ester hydrolysis or internalization of plasma membrane cholesterol.
Topics: Bucladesine; Cell Membrane; Cholesterol; Cholesterol Esters; Cyclic AMP; Hydrolysis; Leydig Cell Tumor; Phosphoproteins; Steroids; Tumor Cells, Cultured | 1996 |
Modulation of steroidogenesis by chloride ions in MA-10 mouse tumor Leydig cells: roles of calcium, protein synthesis, and the steroidogenic acute regulatory protein.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Blotting, Western; Bucladesine; Calcium; Cell Line; Cell Survival; Chlorides; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Kinetics; Leydig Cell Tumor; Leydig Cells; Male; Mice; Mitochondria; Neoplasm Proteins; Phosphoproteins; Progesterone; Rats | 1997 |
Internalized plasma membrane cholesterol passes through an endosome compartment that is distinct from the acid vesicle-lysosome compartment.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Brefeldin A; Bucladesine; Cell Fractionation; Cell Membrane; Chloroquine; Cholesterol; Cholesterol Esters; Cholesterol, LDL; Cyclopentanes; Endosomes; Fluorescent Dyes; Golgi Apparatus; Leydig Cell Tumor; Lysosomes; Mice; Progesterone; Protein Synthesis Inhibitors; Sphingosine; Tumor Cells, Cultured | 1997 |
Retinoic acids up-regulate steroidogenic acute regulatory protein gene.
Topics: Alitretinoin; Animals; Antineoplastic Agents; Bucladesine; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Kinetics; Leydig Cell Tumor; Mice; Mutagenesis, Site-Directed; Neoplasm Proteins; Phosphoproteins; Progesterone; Rats; RNA, Messenger; Sequence Deletion; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1999 |
The role of arachidonic acid on LH-stimulated steroidogenesis and steroidogenic acute regulatory protein accumulation in MA-10 mouse Leydig tumor cells.
Topics: Animals; Arachidonic Acid; Bucladesine; Enzyme Inhibitors; Leydig Cell Tumor; Luteinizing Hormone; Mice; Phospholipases A; Phosphoproteins; Progesterone; Quinacrine; Tumor Cells, Cultured | 1999 |
Effects of extracted Cordyceps sinensis on steroidogenesis in MA-10 mouse Leydig tumor cells.
Topics: Animals; Ascomycota; Bucladesine; Cycloheximide; Drugs, Chinese Herbal; Ethanol; Hypocreales; Leydig Cell Tumor; Leydig Cells; Male; Mice; Neoplasm Proteins; Phosphoproteins; Progesterone; Protein Synthesis Inhibitors; Stimulation, Chemical; Tumor Cells, Cultured; Water | 2000 |
The inhibitory effects of lead on steroidogenesis in MA-10 mouse Leydig tumor cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cadmium; Calcium Channel Blockers; Calcium Channels; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Hydroxycholesterols; Lead; Leydig Cell Tumor; Leydig Cells; Male; Mice; Organometallic Compounds; Phosphoproteins; Pregnenolone; Progesterone; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured | 2001 |
GATA DNA-binding protein expressed in mouse I-10 Leydig testicular tumor cells.
Topics: Animals; Base Sequence; Binding Sites; Bucladesine; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; GATA4 Transcription Factor; Gene Expression; Leydig Cell Tumor; Leydig Cells; Male; Mice; Neoplasm Proteins; Testicular Neoplasms; Transcription Factors; Tumor Cells, Cultured; Zinc Fingers | 2001 |
Heat shock interferes with steroidogenesis by reducing transcription of the steroidogenic acute regulatory protein gene.
Topics: Animals; Blotting, Northern; Blotting, Western; Bucladesine; Cholesterol; DNA; Hot Temperature; Leydig Cell Tumor; Mice; Mitochondria; Nuclear Proteins; Phosphoproteins; Progesterone; Promoter Regions, Genetic; RNA, Messenger; Steroids; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2001 |
Implications of progesterone metabolism in MA-10 cells for accurate measurement of the rate of steroidogenesis.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Antibodies; Bucladesine; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Male; Mice; Pregnenolone; Progesterone; Radioimmunoassay; Steroids; Time Factors; Tumor Cells, Cultured | 2001 |
Effects of steroidogenesis inducing protein (SIP) on steroid production in MA-10 mouse Leydig tumor cells: utilization of a non-cAMP second messenger pathway.
Topics: Animals; Bucladesine; Cyclic AMP; Cycloheximide; Female; Follicular Fluid; Humans; Isoquinolines; Leydig Cell Tumor; Luteinizing Hormone; Mice; Mitochondria; Progesterone; Protein Biosynthesis; Protein Kinase Inhibitors; Proteins; Second Messenger Systems; Signal Transduction; Sulfonamides; Tumor Cells, Cultured | 1992 |
Further evidence that the mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are involved in the acute regulation of steroidogenesis.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Mice; Mitochondria; Molecular Weight; Phenanthrolines; Progesterone; Protein Biosynthesis; Tumor Cells, Cultured | 1992 |
Accumulation and mobilization of triglycerides and cholesteryl esters in Leydig tumor cells.
Topics: Algestone; Animals; Bucladesine; Cholesterol Esters; Leydig Cell Tumor; Lipid Mobilization; Lipoproteins, LDL; Male; Mice; Oleic Acid; Oleic Acids; Progesterone; Triglycerides; Tumor Cells, Cultured | 1992 |
A cholesteryl ester hydrolase inhibitor blocks cholesterol translocation into the mitochondria of MA-10 Leydig tumor cells.
Topics: Biological Transport; Bucladesine; Cell Survival; Cholesterol; Humans; Hydroxycholesterols; Leydig Cell Tumor; Mitochondria; Organophosphorus Compounds; Progesterone; Sterol Esterase; Tumor Cells, Cultured; Umbelliferones | 1992 |
Cyclic adenosine 3',5'-monophosphate negatively regulates clusterin gene expression in Leydig tumor cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Bucladesine; Cell Line; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Clusterin; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Glycoproteins; Kinetics; Leydig Cell Tumor; Male; Mice; Molecular Chaperones; Poly A; Progesterone; Rats; RNA; RNA, Messenger; RNA, Neoplasm; Tubulin | 1992 |
Effect of different steroidogenic stimuli on protein phosphorylation and steroidogenesis in MA-10 mouse Leydig tumor cells.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Colforsin; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Leydig Cell Tumor; Leydig Cells; Male; Mice; Mitochondria; Phosphoproteins; Phosphorylation; Progesterone; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
A novel method to modulate desensitization and truncation of luteinizing hormone receptors using antisense oligodeoxynucleotides.
Topics: Animals; Base Sequence; Bucladesine; Cyclic AMP; Leydig Cell Tumor; Luteinizing Hormone; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Pregnenolone; Receptors, LH; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Isoelectric Point; Leydig Cell Tumor; Mice; Mitochondria; Molecular Weight; Peptide Mapping; Progesterone; Protein Biosynthesis; Rats; Serine Endopeptidases; Trypsin; Tumor Cells, Cultured | 1991 |
Effect of cholesterol transport inhibitors on steroidogenesis and plasma membrane cholesterol transport in cultured MA-10 Leydig tumor cells.
Topics: Biological Transport; Bucladesine; Cell Membrane; Cholesterol; Cholesterol, LDL; Colchicine; Cytochalasin D; Leydig Cell Tumor; Nigericin; Pregnenolone; Progesterone; Trifluoperazine; Tumor Cells, Cultured | 1990 |
Induction of lutropin receptors by lutropin and cyclic AMP in cultured mouse tumour (MA10) Leydig cells.
Topics: Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cycloheximide; Dactinomycin; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Mice; Receptors, LH; Trypsin; Tumor Cells, Cultured | 1990 |
Evidence for the functional coupling of cyclic AMP in MA-10 mouse Leydig tumour cells.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Leydig Cell Tumor; Mice; Mitochondria; Molecular Weight; Progesterone; Tumor Cells, Cultured | 1990 |
Cholesterol movement between the plasma membrane and the cholesteryl ester droplets of cultured Leydig tumour cells.
Topics: Animals; Bucladesine; Cell Membrane; Cholesterol; Cholesterol Esters; Epidermal Growth Factor; Fibroblasts; Humans; Intracellular Fluid; Iron Radioisotopes; Leydig Cell Tumor; Lipoproteins, LDL; Mice; Transferrin | 1990 |
Induction of renin activity by gonadotropic hormones in cultured Leydig tumor cells.
Topics: Angiotensin I; Animals; Bucladesine; Cells, Cultured; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Enzyme Induction; Epidermal Growth Factor; Leydig Cell Tumor; Luteinizing Hormone; Male; Mice; Protein Biosynthesis; Renin; RNA; Trypsin | 1985 |
Epidermal growth factor activates steroid biosynthesis in cultured Leydig tumor cells without affecting the levels of cAMP and potentiates the activation of steroid biosynthesis by choriogonadotropin and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Aminoglutethimide; Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Epidermal Growth Factor; Leydig Cell Tumor; Mice; Phosphodiesterase Inhibitors; Progesterone; Steroids | 1987 |
Initial characterization of a subclone of the MA-10 mouse Leydig tumor cell line.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Clone Cells; Cyclic AMP; Leydig Cell Tumor; Mice; Pregnenolone; Progesterone; Testosterone; Tumor Cells, Cultured | 1989 |
Transiently elevated levels of c-fos and c-myc oncogene messenger ribonucleic acids in cultured murine Leydig tumor cells after addition of human chorionic gonadotropin.
Topics: Animals; Blotting, Northern; Bucladesine; Chorionic Gonadotropin; Kinetics; Leydig Cell Tumor; Mice; Nucleic Acid Hybridization; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tumor Cells, Cultured | 1989 |
Inhibition of hCG- and cAMP-stimulated progesterone production in MA-10 mouse Leydig tumor cells by ketoconazole.
Topics: Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Hydroxycholesterols; Ketoconazole; Kinetics; Leydig Cell Tumor; Mice; Progesterone | 1989 |
Regulation of the differentiated functions of Leydig tumor cells by epidermal growth factor.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Epidermal Growth Factor; In Vitro Techniques; Leydig Cell Tumor; Mice; Receptors, LH; Steroids; Time Factors; Tumor Cells, Cultured | 1989 |
Cyclic AMP mediated modification of cholesterol traffic in Leydig tumor cells.
Topics: Animals; Bucladesine; Cell Line; Cell Membrane; Cholesterol; Cholesterol, LDL; Cyclic AMP; Fibroblasts; Humans; Kinetics; Leydig Cell Tumor; Male; Membrane Lipids; Progesterone; Skin | 1987 |
Induction of mitochondrial proteins in MA-10 Leydig tumour cells with human choriogonadotropin.
Topics: Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Leydig Cell Tumor; Mice; Mitochondria; Neoplasm Proteins; Progesterone; Stimulation, Chemical | 1988 |
Down-regulation of gonadotropin and beta-adrenergic receptors by hormones and cyclic AMP.
Topics: Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Glioma; Isoproterenol; Kinetics; Leydig Cell Tumor; Mice; Rats; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, LHRH | 1985 |
Are polyphosphorylated phospholipids involved in the hormonal control of cholesterol side-chain cleavage activity in tumour Leydig cells?
Topics: Animals; Bucladesine; Cardiolipins; Cycloheximide; Cytochrome P-450 Enzyme System; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mitochondria; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Pregnenolone; Quinacrine | 1985 |
Gonadotropin-mediated desensitization in a murine Leydig tumor cell line does not alter the regulatory and catalytic components of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Drug Tolerance; Guanosine Triphosphate; Isoproterenol; Leydig Cell Tumor; Membrane Fusion; Mice; Protein Biosynthesis; Receptors, Adrenergic, beta | 1986 |
Constitutive steroidogenesis in the R2C Leydig tumor cell line is maintained by the adenosine 3',5'-cyclic monophosphate-independent production of a cycloheximide-sensitive factor that enhances mitochondrial pregnenolone biosynthesis.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Cytoplasm; Lactates; Leydig Cell Tumor; Leydig Cells; Male; Mitochondria; Pregnenolone; Progesterone; Protein Kinases; Rats | 1987 |
Aromatase activity in a rat Leydig cell tumor.
Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Estrone; Leydig Cell Tumor; Male; Neoplasm Transplantation; Rats; Rats, Inbred WF; Testicular Neoplasms; Testosterone; Tetradecanoylphorbol Acetate; Water | 1987 |
Regulation of the cholesterol ester cycle of cultured Leydig tumor cells.
Topics: Animals; Bucladesine; Cell Line; Cholesterol Esters; Cyclic AMP; Hydrolysis; Kinetics; Leydig Cell Tumor; Mice; Steroids; Sterol O-Acyltransferase | 1987 |