Compounds > bu 224

bu 224 and Disease Models, Animal

bu 224 has been researched along with Disease Models, Animal in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Birch, AM; Davis, N; Golbano, A; Katsouri, L; Mirzaei, N; Mota, BC; Nagy, I; Nutt, DJ; Palmer, EOC; Riggall, LJ; Romero-Molina, C; Sastre, M; Tyacke, R1
Jia, S; Li, JX; Qiu, Y; Thorn, DA; Zhang, Y1
Cheng, JT; Chung, HH; Ko, WC; Liu, IM1
Cheng, JT; Chung, HH; Liu, IM; Su, CH1
Li, JX; Winter, JC; Zhang, Y1
Chen, MF; Cheng, JT; Chiu, NH; Chou, MT; Chung, HH; Mar, GY1

Other Studies

8 other study(ies) available for bu 224 and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.
    British journal of pharmacology, 2021, Volume: 178, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognition; Disease Models, Animal; Female; Imidazoles; Imidazolines; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic

2021
Antinociceptive effects of imidazoline I2 receptor agonists in the formalin test in rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Benzofurans; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Imidazoline Receptors; Injections, Intraperitoneal; Injections, Intraventricular; Locomotion; Male; Pain; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Time Factors

2016
Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats.
    Neuroscience letters, 2008, Dec-19, Volume: 448, Issue:1

    Topics: Agmatine; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Imidazoles; Imidazoline Receptors; Insulin; Insulin Resistance; Ligands; Male; Rats; Rats, Wistar

2008
Activation of I2-imidazoline receptors by agmatine improved insulin sensitivity through two mechanisms in type-2 diabetic rats.
    Neuroscience letters, 2009, Jul-03, Volume: 457, Issue:3

    Topics: Adrenalectomy; Agmatine; Analysis of Variance; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fructose; Glucose Clamp Technique; Hypoglycemic Agents; Imidazoles; Imidazoline Receptors; Insulin; Insulin Resistance; Male; Rats; Rats, Wistar

2009
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands.
    European journal of pharmacology, 2011, Nov-01, Volume: 669, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine

2011
Changes of imidazoline receptors in spontaneously hypertensive rats.
    International journal of experimental pathology, 2013, Volume: 94, Issue:1

    Topics: Agmatine; Animals; Antihypertensive Agents; Aorta, Thoracic; Benzofurans; Blood Pressure; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Imidazoline Receptors; KATP Channels; Male; Potassium Channel Blockers; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation; Vasodilation; Vasodilator Agents

2013